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Title:
HYDROGEL FOR CELL CULTURE, GEL KIT, METHOD FOR PRODUCING CELL CULTURE, AND METHOD FOR PRODUCING HYDROGEL FOR CELL CULTURE
Document Type and Number:
WIPO Patent Application WO/2020/004646
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a technique for controlling gene expression while reducing growth activity caused by unknown growth factors mixed in scaffold raw materials during cell culture using hydrogel as the scaffold. The present invention provides a hydrogel for cell culture: having cell growth activity, as calculated in terms of fibroblast growth factor-1 activity, of 100 pg/mL or less; an elastic modulus of 0.1-500 kPa; and a radiation-induced cross linked structure of a hydrophilic polymer.

Inventors:
TAGUCHI MITSUMASA (JP)
OYAMA TOMOKO (JP)
KIMURA ATSUSHI (JP)
OYAMA KOTARO (JP)
ISHIHARA HIROSHI (JP)
SHIMOKAWA TAKASHI (JP)
Application Number:
PCT/JP2019/025916
Publication Date:
January 02, 2020
Filing Date:
June 28, 2019
Export Citation:
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Assignee:
NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECH (JP)
International Classes:
C12M3/00; C12N5/00; C07K14/78
Foreign References:
JP2008212026A2008-09-18
JP2015035978A2015-02-23
JP2013155354A2013-08-15
JP2004091450A2004-03-25
JP2004115413A2004-04-15
JP2014507135A2014-03-27
Other References:
OYAMA, TOMOKO: "Development of radiation cross-linked gelatin hydrogel and application to functional scaffold materials", RADIATION CHEMISTR Y, vol. 103, 2017, pages 39 - 40
Attorney, Agent or Firm:
NIIYAMA Yuichi (JP)
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