Title:
HYDROXAMIC ACID DERIVATIVES AS METALLOPROTEASE INHIBITORS
Document Type and Number:
WIPO Patent Application WO2005117882
Kind Code:
A9
Abstract:
The present invention provides compounds of Formula (I ) or (II), salt form or prodrug thereof, wherein variables are defined herein, that are modulators of metalloproteases such as matrix metalloproteases (MMPs) and ADAMs. The compounds or compositions described herein can be used to treat diseases associated with metalloprotease activity including, for example, arthritis, cancer, cardiovascular disorders, skin disorders, inflammation or allergic conditions.
Inventors:
BURNS DAVID M (US)
YAO WENQING (US)
HE CHUNHONG (US)
YAO WENQING (US)
HE CHUNHONG (US)
Application Number:
PCT/US2005/013434
Publication Date:
March 01, 2007
Filing Date:
April 19, 2005
Export Citation:
Assignee:
INCYTE CORP (US)
BURNS DAVID M (US)
YAO WENQING (US)
HE CHUNHONG (US)
BURNS DAVID M (US)
YAO WENQING (US)
HE CHUNHONG (US)
International Classes:
C07D207/00; A61K31/452; A61K31/4545; A61K31/4709; A61K31/496; C07D209/04; C07D209/52; C07D211/00; C07D211/96; C07D223/00; C07D295/00; C07D401/00; C07D401/14; C07D405/00; C07D405/12; C07D405/14; C07D409/00; C07D411/00; C07D413/00; C07D417/00; C07D419/00; C07D421/00; C07D487/00
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