Title:
HYDROXYAMIDE DERIVATIVE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/222115
Kind Code:
A1
Abstract:
Provided in the present application is a hydroxyamide derivative represented by formula (I), and a tautomer, stereoisomer, solvate, metabolite, isotopically-labeled compound, pharmaceutically acceptable salt or co-crystal thereof. The compound provided in the present application has an inhibitory effect on both HDAC and LSD1, and can be used for treating diseases mediated by LSD1 and/or HDAC.
Inventors:
CHEN SHOUJUN (CN)
YAN JIAMING (CN)
DING ZHAO (CN)
LI MIN (CN)
WANG HAIBO (CN)
YAN JIAMING (CN)
DING ZHAO (CN)
LI MIN (CN)
WANG HAIBO (CN)
Application Number:
PCT/CN2023/095304
Publication Date:
November 23, 2023
Filing Date:
May 19, 2023
Export Citation:
Assignee:
SICHUAN HUIYU PHARMACEUTICAL CO LTD (CN)
SICHUAN HUIYU SEACROSS PHARMACEUTICAL TECH CO LTD (CN)
SICHUAN HUIYU SEACROSS PHARMACEUTICAL TECH CO LTD (CN)
International Classes:
C07D401/04; A61K31/439; A61K31/4427; A61K31/4545; A61K31/506; A61P35/00; A61P37/00; C07D207/14; C07D211/58; C07D401/14; C07D403/10; C07D405/14; C07D409/06; C07D409/14; C07D413/04; C07D413/14; C07D417/14; C07D471/08; C07D471/10; C07D487/04
Domestic Patent References:
| WO2019134087A1 | 2019-07-11 | |||
| WO2003076430A1 | 2003-09-18 | |||
| WO2010100475A1 | 2010-09-10 | |||
| WO2020193431A1 | 2020-10-01 |
Foreign References:
| CN103328446A | 2013-09-25 | |||
| CN106928198A | 2017-07-07 | |||
| CN101445469A | 2009-06-03 | |||
| CN109810108A | 2019-05-28 | |||
| CN1639125A | 2005-07-13 | |||
| US20050234033A1 | 2005-10-20 |
Attorney, Agent or Firm:
MERITS IP LTD. (CN)
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