Discussion of the Background The malfunctioning of protein kinases (PKs) is the hallmark of numerous diseases.

A large share of the oncogenes and proto-oncogenes involved in human cancers code for PKs. The enhanced activities of PKs are also implicated in many non-malignant diseases such as benign prostate hyperplasia, familial adenomatosis, polyposis, neuro-fibromatosis, psoriasis, vascular smooth cell proliferation associated with atherosclerosis, pulmonary fibrosis, arthritis glomerulonephritis and post-surgical stenosis and restenosis.

PKs are also implicated in inflammatory conditions and in the multiplication of viruses and parasites. PKs may also play a major role in the pathogenesis and development of neurodegenerative disorders.

For a general reference to PKs malfunctioning or disregulation see, for instance, Current Opinion in Chemical Biology 1999,3, 459-465.

SUMMARY OF THE INVENTION The present inventors have now discovered that some hydroxyphenyl-pyrazoles are endowed with multiple protein kinase inhibiting activity and are thus useful in therapy in the treatment of diseases caused by and/or associated with disregulated protein kinases.

As such, it is an object of the invention to provide compounds which are useful as therapeutic agents against a host of diseases caused by a disregulated protein kinase activity.

It is another object to provide compounds endowed with multiple protein kinase inhibiting activity.

More specifically, the hydroxyphenyl-pyrazoles of this invention are useful in the treatment of a variety of cancers including, but not limited to: carcinoma such as bladder, breast, colon, kidney, liver, lung, including small cell lung cancer, esophagus, gall-bladder, ovary, pancreas, stomach, cervix, thyroid, prostate, and skin, including squamous cell carcinoma; hematopoietic tumors of lymphoid lineage, including leukemia, acute lymphocitic leukemia, acute lymphoblastic leukemia, B-cell lymphoma, T-cell-lymphoma, Hodgkin's lymphoma, non-Hodgkin's lymphoma, hairy cell lymphoma and Burkett's lymphoma ; hematopoietic tumors of myeloid lineage, including acute and chronic myelogenous leukemias, myelodysplastic syndrome and promyelocytic leukemia; tumors of mesenchymal origin, including fibrosarcoma and rhabdomyosarcoma; tumors of the central and peripheral nervous system, including astrocytoma, neuroblastoma, glioma and schwannomas; other tumors, including melanoma, seminoma, teratocarcinoma, osteosarcoma, xeroderma pigmentosum, keratocanthoma, thyroid follicular cancer and Kaposi's sarcoma.

Due to the key role of PKs in the regulation of cellular proliferation, these hydroxyphenyl- pyrazoles are also useful in the treatment of a variety of cell proliferative disorders such as, for instance, benign prostate hyperplasia, familial adenomatosis, polyposis, neuro- fibromatosis, psoriasis, vascular smooth cell proliferation associated with atherosclerosis, pulmonary fibrosis, arthritis glomerulonephritis and post-surgical stenosis and restenosis.

The compounds of the invention can be useful in the treatment of Alzheimer's disease, as suggested by the fact that cdk5 is involved in the phosphorylation of tau protein (J.

Biochem. , 117,741-749, 1995).

The compounds of this invention, as modulators of apoptosis, may also be useful in the treatment of cancer, viral infections, prevention of AIDS development in HIV-infected individuals, autoimmune diseases and neurodegenerative disorders.

The compounds of this invention may be useful in inhibiting tumor angiogenesis and metastasis.

The compounds of the invention are useful as cyclin dependent kinase (cdk) inhibitors and also as inhibitors of other protein kinases such as, for instance, protein kinase C in different isoforms, Met, PAK-4, PAK-5, ZC-1, STLK-2, DDR-2, Aurora 1, Aurora 2, Bub-1, PLK, Chkl, Chk2, HER2, rafl, MEK1, MAPK, EGF-R, PDGF-R, FGF-R, IGF-R, VEGF-R, PI3K, weel kinase, Src, Abl, Akt, ILK, MK-2, IKK-2, Cdc7, Nek, and thus be effective in the treatment of diseases associated with other protein kinases.

Accordingly, the present invention provides a method for treating diseases caused by and/or associated with an altered protein kinase activity which comprises administering to a mammal in need thereof an effective amount of a hydroxyphenyl-pyrazole derivative represented by formula (I) : wherein R1 to R4 independently represent - hydrogen or halogen atom, hydroxy, nitro or NR8R9 group, wherein R8 and Rg independently represent hydrogen or an optionally substituted group selected from Cl-C6 alkyl, aryl, aryl Cl-C6 alkyl, C3-C7 cycloalkyl and saturated or unsaturated heterocyclyl group, or a residue of formula CORIO, CONHRIO or S02Rio in which Rio is hydrogen atom or an optionally substituted group selected from Cl-C6 alkyl, aryl, aryl Cl-C6 alkyl, saturated or unsaturated C3-C7 cycloalkyl or saturated or unsaturated heterocyclyl group, or - an optionally substituted group selected from a straight or branched Cl-C6 alkyl, aryl, aryl Cl-C6 alkyl, a saturated or unsaturated C3-C7 cycloalkyl or cycloalkoxy group, saturated or unsaturated heterocyclyl, Cl-C6 alkoxy, aryloxy, aryl Cl-C6 alkoxy ; R5 and R6 independently represent hydrogen or an optionally substituted group selected from Cl-C6 alkyl, aryl, aryl Cl-C6 alkyl, C3-C7 cycloalkyl and saturated or unsaturated heterocyclyl, R7 is a substituent attached at one of the two nitrogen atoms of the pyrazole ring having the formula CONHRzo, CSNHRio, SO2Rio, CORIO or COORio, in which Rio is as above defined, or a pharmaceutically acceptable salt thereof.

In a preferred embodiment of the method described above, the disease caused by and/or associated with an altered protein kinase activity is selected from the group consisting of cancer, cell proliferative disorders, Alzheimer's disease, viral infections, auto-immune diseases and neurodegenerative disorders.

Specific types of cancer that may be treated according to the invention include carcinoma, squamous cell carcinoma, hematopoietic tumors of myeloid or lymphoid lineage, tumors of mesenchymal origin, tumors of the central and peripheral nervous system, melanoma, seminoma, teratocarcinoma, osteosarcoma, xeroderoma pigmentosum, keratoxanthoma, thyroid follicular cancer and Kaposi's sarcoma.

In another preferred embodiment of the method described above, the cell proliferative disorder is selected from the group consisting of benign prostate hyperplasia, familial adenomatosis polyposis, neuro-fibromatosis, psoriasis, vascular smooth cell proliferation associated with atherosclerosis, pulmonary fibrosis, arthritis glomerulonephritis and post- surgical stenosis and restenosis. In addition, the method object of the present invention, provides tumor angiogenesis and metastasis inhibition.

The present invention also provides a hydroxyaryl-pyrazole derivative represented by formula (I): wherein Rl to R4 independently represent - hydrogen or halogen atom, hydroxy, nitro or NRsR9 group, wherein Rg and Rg independently represent hydrogen or an optionally substituted group selected from Cl-C6 alkyl, aryl, aryl Cl-C6 alkyl, C3-C7 cycloalkyl and saturated or unsaturated heterocyclyl group, or a residue of formula CORIO, CONHRIO or SO2Rzo in which Rio is hydrogen atom or an optionally substituted group selected from Cl-C6 alkyl, aryl, aryl Cl-C6 alkyl, saturated or unsaturated C3-C7 cycloalkyl or saturated or unsaturated heterocyclyl group, or - an optionally substituted group selected from a straight or branched Cl-C6 alkyl, aryl, aryl Cl-C6 alkyl, a saturated or unsaturated C3-C6 cycloalkyl or cycloalkoxy group, saturated or unsaturated heterocyclyl, Cl-C6 alkoxy, aryloxy, aryl Cl-C6 alkoxy ; R5 and R6 independently represent hydrogen or an optionally substituted group selected from Cl-C6 alkyl, aryl, aryl Cl-C6 alkyl, C3-C7 cycloalkyl and saturated or unsaturated heterocyclyl, R7 is a substituent attached at one of the two nitrogen atoms of the pyrazole ring having the formula CONHRIO, CSNHRIO, S02Rio, CORIO or COORIO, in which Rio is as above defined, with the following provisos: - when R7 is CONH2 or CSNH2 and R5 is H or CH3, then R6 is not H, CH3 or phenyl group, - when R7 is CO R'll in which R'n is an optionally substituted Cl-C6 alkyl, phenyl, or saturated or unsaturated heterocyclyl group, and R5 is H or phenyl group, then R6 is not H, CH3 or an optionally substituted phenyl, -when R7 is C02C (CH3) 3 or C02CH3 and R5 is H, then R6 is not an optionally substituted phenyl group; or a pharmaceutically acceptable salt thereof.

The hydroxyphenyl-pyrazole derivatives of formula (1), object of the invention, are obtainable through a synthetic process comprising well known reactions carried out according to conventional techniques, as well as through a new and extremely versatile solid-phase combinatorial process, being both comprised within the scope of the invention.

The present invention also provides a pharmaceutical composition comprising the hydroxyaryl-pyrazole derivatives of formula (I) and at least one pharmaceutically acceptable excipient, carrier or diluent.

A more complete appreciation of the invention and many of the attendant advantages thereof will be readily obtained as the same becomes better understood by reference to the following detailed description.

DETAILED DESCRIPTION OF THE INVENTION Some hydroxyphenyl-pyrazole derivatives structurally close to the compounds of formula (1) are known in the art. Among them are, as an example, certain pyrazoles active as antibacterial agents were studied (Mogilaiah et al, Indian J. Chem. , B, 2001,40B (1), p. 43- 48; Naik, S. M. et al. Asian J. Chem. , 11 (4), 1537-1539 and 1522-1524,1999), and the reactivity of other derivatives was for instance discussed in Hamed, Ashraf et al., An.

Quim. (1994), 90 (5-6), 359-64 and in Rampey, Mary E. et al. Photochem. Photobiol., 70 (2), 176-183, 1999.

The compounds of formula (I), object of the present invention, may have asymmetric carbon atoms and may therefore exist either as racemic admixtures or as individual optical isomers. Accordingly, all the possible isomers and their admixtures and of both the metabolites and the pharmaceutically acceptable bio-precursors (otherwise referred to as pro-drugs) of the compounds of formula (I), as well as any therapeutic method of treatment comprising them, are also within the scope of the present invention.

As stated above, as will be readily appreciated, the R7 substituent on the pyrazole ring may be on one of the two nitrogens in the compounds of the invention: wherein Rl to R4, R5, R6 and R7 are as defined above.

Accordingly, in the present invention and unless otherwise indicated, the general formula I comprises both the compounds of formula (I') and the other of formula (I").

As used herein, unless otherwise specified, with the term straight or branched Ci-C6 alkyl, we intend a group such as, for instance, methyl, ethyl, n-propyl, isopropyl, n-butyl, isobutyl, sec-butyl, tert-butyl, n-pentyl, neopentyl, n-hexyl, isohexyl, and the like.

With the term aryl we intend an aromatic carbocycle such as, for instance, phenyl, biphenyl, 1-naphthyl, 2-naphthyl, and the like.

With the term saturated or unsaturated C3-C7 cycloalkyl group we intend, for instance, cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, cyclopentenyl, cyclohexenyl, and the like.

Unless otherwise specified, saturated or unsaturated cycloalkyl groups can be further condensed with 1 or 2 benzene rings are, for instance, 1, 2,3, 4-tetrahydro-naphthalene-2-yl, fluorene-9-yl, and the like.

The term"heterocyclyl"as used herein refers to a 3-to 7-membered, substituted or unsubstituted, saturated or unsaturated heterocyclyl ring, containing at least one heteroatom selected from O, S and N, any ring carbon may be oxidized as a carbonyl, and wherein said heterocyclyl ring may be optionally fused to a second 5-or 6-membered, saturated or unsaturated heterocyclyl ring, or to a C3-C7 cycloalkyl ring, or to a benzene or naphthalene ring. With the term 3-to 7-membered heterocycle with at least one heteroatom selected among nitrogen, oxygen or sulphur, we intend a saturated, partly unsaturated or fully unsaturated either aromatic or non aromatic heterocycle such as, for instance, thiophene, furan, pyrrole, imidazole, pyrazole, thiazole, isothiazole, oxazole, isoxazole, pyridine, pyrazine, pyrimidine, pyridazine, pyrrolidine, pyrroline, imidazolidine, imidazoline, piperidine, piperazine, morpholine, tetrahydrofuran, tetrahydropyran, tetrahydrothiopyran, and the like.

With the term optionally fused heterocycle and unless otherwise indicated we intend any of the above defined heterocycles further condensed, through any one of the available bonds, with 5-or 6-membered, saturated or unsaturated heterocyclyl ring, or to a C3-C7 cycloalkyl ring, or to a benzene or naphthalene ring such as, for instance, quinoline, isoquinoline, chroman, chromene, thionaphthene, indoline, and the like.

The term"aryl Cl-C6 alkyl"refer to a straight or branched chain alkyl moiety having from 1 to 6 carbon atoms substituted with at least one aryl group as defined above, such as, for instance, benzyl, phenylethyl, benzhydryl, benzyloxy and the like.

With the term halogen atom, we intend fluoro, bromo, chloro or iodo atom.

The term"optionally substituted"means that the group may be substituted or unsubstituted ; the substituents which may be present in the alkyl, cycloalkyl, aryl, arylcycloalkyl, alkoxy, aryloxy, cycloalkoxy, alkenyl or heterocyclyl groups in any of the above definitions of Rl-Rlo include the following: - halo (i. e. , fluoro, bromo, chloro or iodo) ; - hydroxy ; - nitro ; - azido ; - mercapto (i. e. ,-SH), and acetyl or phenylacetyl esters thereof (i. e. ,-SCOCH3 and- SCOCH2C6H5) ; - amino (i. e.,-NH2 or-NHRI or-NRIRn, wherein Rl and Roll, which are the same or different, are straight or branched Ci-C6 alkyl, phenyl, biphenyl (i. e.,-C6H4-C6Hs), or benzyl groups, optionally substituted by hydroxy, methoxy, methyl, amino, methylamino, dimethylamino, chloro or fluoro; or RI and Ru taken together with the nitrogen atom to which they are attached form a heterocyclic ring such as morpholino, pyrrolidino, piperidino, pyperazino or N-methylpyperazino; - guanidino, i. e.,-NHC (=NH) NH2; - formyl (i. e. -CHO) ; - cyano ; - carboxy (i. e. -COOH), or esters thereof (i. e., -COORI), or amides thereof (i. e.,-CONH2,- CONHRI or-CONHRIRIl), wherein Rl and Rll are as defined above, and including morpholino-amides, pyrrolidino-amides, and carboxymethylamides-CONHCH2COOH ; - sulfo (i. e., -SO3H) ; - acyl, i. e.,-C (O) RI, wherein RI is as defined above, including monofluoroacetyl, difluoroacetyl, trifluoroacetyl; - carbamoyloxy (i. e.,-OCONH2) and N-methylcarbamoyloxy ; -acyloxy, i. e.,-OC (O) RI wherein RI is as defined above, or formyloxy ; -acylamino, i. e.,-NHC (O) RI, or-NHC (O) ORI, wherein RI is as defined above or is a group -(CH2)tCOOH where t is 1,2 or 3; - ureido, i. e. ,-NH (CO) NH2,-NH (CO) NHRI,-NH (CO) NRIRII, wherein RI and Ri are as defined above, including-NH (CO)- (4-morpholino),-NH (CO)- (l-pyrrolidino),-NH (CO)- (1- piperazino), -NH (CO)- (4-methyl-1-piperazino) ; - sulfonamido, i. e., -NHSO2RI wherein RI is as defined above; - a group -(CH2) tCOOH, and esters and amides thereof, i. e.,-(CH2) tCOORl and- (CH2) tCONH2, -(CH2)tCONHRI, -(CH2)tCONRIRII, wherein t, RI and RII are as defined above ; -a group-NH (SO2) NH2,-NH (SO2) NHRl,-NH (SO2) NRlRll, wherein RI and 0 are as defined above, including-NH (S02)- (4-morpholino),-NH (S02)- (l-pyrrolidino),-NH (S02)- (1-piperazino),-NH (SO2)- (4-methyl-1-piperazino) ; - a group-OC (O) OR', wherein RI is as defined above; -a group-ORl, wherein RI is as defined above, including-OCH2COOH ; - a group -O-CH2-O-, methylendioxy or-0-CH2-CH2-0-, ethylendioxy ; -a group-SRl, wherein Rl is as defined above, including-SCH2COOH ; - a group-S (O) RI, wherein RI is as defined above; - a group-S (O2) RI, wherein RI is as defined above; -a group-SO2NH2,-SO2NHRl, or-SO2NRlRll, wherein RI and RII are as defined above; -Cl-C6 alkyl or C2-C6 alkenyl; - C3-C7 cycloalkyl ; - substituted methyl selected from chloromethyl, fluoromethyl, difluoromethyl, trifluoromethyl, aminomethyl, N,N-dimethylaminomethyl, azidomethyl, cyanomethyl, carboxymethyl, sulfomethyl, carbamoylmethyl, carbamoyloxymethyl, hydroxymethyl, methoxycarbonylmethyl, ethoxycarbonylmethyl, tert-butoxycarbonyhnethyl and guanidinomethyl.

Most preferred substituents are methoxy, trifluoromethyl, methylendioxy, dimethylamino, and ethoxycarbonyl groups.

When present, carboxy, hydroxy, mercapto and amino groups may be either free or in a protected form. Protected forms of said groups are any of those generally known in the art.

Preferably, carboxy groups are protected as esters thereof, in particular methyl, ethyl, tert- butyl, benzyl, and 4-nitrobenzyl esters. Preferably, hydroxy groups are protected as silyl- ethers, ethers or esters thereof, in particular trimethyl silyl, tert-butyldiphenyl silyl, triethyl silyl, triisopropyl silyl or tert-butyldimethylsilyl ethers, methoxymethyl ethers, tetrahydropyranyl ethers, benzyl ethers, acetates or benzoates. Preferably, mercapto groups are protected as thioethers or thioesters, in particular tert-butyl thioethers, thioacetates or thiobenzoates. Preferably, amino groups are protected as carbamates, e. g. tert- butoxycarbonyl derivatives, or as amides, e. g. acetamides and benzamides.

Furthermore, hydrates, solvates of compounds of formula (1), and physiologically hydrolyzable derivatives (i. e. , prodrugs) of compounds of formula (1) are included within the scope of the present invention.

With the term oxo we intend a carbonyl (>C=O) group.

With the term perfluorinated alkyl we intend any alkyl group as above defined being substituted by two or more fluorine atoms such as, for instance, trifluoromethyl, 2,2, 2- trifluoroethyl, 1, 1-difluoroethyl, and the like.

From all of the above, it is clear to the skilled man that any of the groups or substituents being defined, for instance, as arylalkyl, alkoxy, cycloalkoxy, aryloxy, arylalkyloxy and the like, have to be construed from the names of the groups from which they originate.

As an example, unless specifically noted otherwise, any arylalkyloxy group has to be intended as an alkyloxy wherein the alkyl moiety is substituted by at least one aryl, both aryl and alkyl being as above defined.

Pharmaceutically acceptable salts of the compounds of formula (I) are the acid addition salts with inorganic or organic, e. g. nitric, hydrochloric, hydrobromic, sulphuric, perchloric, phosphoric, acetic, trifluoroacetic, propionic, glycolic, lactic, oxalic, malonic, malic, maleic, tartaric, citric, benzoic, cinnamic, mandelic, methanesulphonic, isethionic and salicylic acid, as well as the salts with inorganic or organic bases, e. g. alkali or alkaline-earth metals, especially sodium, potassium, calcium or magnesium hydroxides, carbonates or bicarbonates, acyclic or cyclic amines, preferably methylamine, ethylamine, diethylamine, triethylamine or piperidine.

Within the compounds of formula (1) object of the invention, the R7 group can be on one of the two nitrogen atoms of the pyrazole ring ; preferably, the said R7 is on the nitrogen in position meta with respect to the hydroxy-phenyl ring, as depicted in the formula I'above.

Preferred compounds of formula (1) are the compounds wherein Ri, R4 and R5 are hydrogen atoms.

Other preferred compounds of formula (I) are the compounds wherein Ra and R3 are independently selected from - hydrogen or halogen atom, - an optionally substituted straight or branched Cl-C6 alkyl or Cl-C6 alkoxy, and - NR8R9 group, wherein R8 and Rg independently represent hydrogen atom or a residue of formula CORIO wherein Rio is an optionally substituted group selected from aryl and saturated or unsaturated heterocyclyl group.

Still more preferred, within this class, are the compounds of formula (1) wherein R2 and R3 are selected from hydrogen, chlorine or fluorine atom, optionally substituted straight or branched Cl-C6 alkyl or Cl-C6 alkoxy and NRsR9 group, wherein R8 and R9 independently represent hydrogen atom or a residue of formula CORIO wherein Rio is an optionally substituted group selected from phenyl, 1-naphthyl, 2-naphtyl, biphenyl, pyridyl, pyrazolyl, thienyl, isoxazolyl, thiazolyl, pyrazolyl, fluorene-9-yl, piperidine or tetrahydroquinoline.

Another preferred class of compounds of formula (I) are the compounds wherein R6 is an optionally substituted group selected from Cl-C6 alkyl, aryl, C3-C7 cycloalkyl and saturated or unsaturated heterocyclyl group.

Still more preferred, within this class, are the compounds of formula (I) wherein R6 is an optionally substituted group selected from straight or branched Cl-C6 alkyl, C3-C7 cycloalkyl, phenyl, 1-naphthyl, 2-naphtyl, biphenyl, pyridyl, pyrazolyl, thienyl, isoxazolyl, thiazolyl, pyrazolyl, fluorene-9-yl, piperidine or tetrahydroquinoline.

According to another preferred embodiment of the invention, the compounds of formula (I) are pyrazole derivatives wherein R7 represents a group of formula CONHRIO, in which Rio is hydrogen atom or an optionally substituted group selected from Cl-C6 alkyl, aryl, aryl Cl-C6 alkyl, C2-C8 alkenyl, C3-C7 cycloalkyl or saturated or unsaturated heterocyclyl group. More preferably, R7 represents a group of formula CONHRIO, in which Rio is Ci-C6 alkyl, phenyl, 1-naphthyl, 2-naphtyl, biphenyl, benzyl, allyl or phenethyl group.

Specific, not limiting, examples of the compounds of formula (I) of the invention, whenever appropriate in the form of pharmaceutically acceptable salts, are the following: Ia. 5-Cyclopropyl-3- [2-hydroxy-4- (4-methoxy-benzoylamino)-phenyl]-pyrazole-1- carboxylic acid butylamide; Ib. N-ethyl-3-(2-hydroxyphenyl)-5-pyridin-4-yl-lH-pyrazole-l-car boxamide ; Ic. 5-cyclopropyl-3-(2-hydroxyphenyl)-N-propyl-1H-pyrazole-1-car boxamide ; Id. ethylN-{[5-cyclopropyl-3-(2-hydroxyphenyl)-lH-pyrazol-l-yl] carbonyl} glycinate; Ie. N-allyl-5-cyclopropyl-3- (2-hydroxyphenyl)-lH-pyrazole-l-carboxamide ; If. N-cyclohexyl-5-cyclopropyl-3- (2-hydroxyphenyl)-lH-pyrazole-l-carboxamide ; Ig. 5-cyclopropyl-N-ethyl-3-(2-hydroxy-4-{[3- (trifluoromethyl) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide ; Ih. ethyl-N- { [5- [2- (dimethylamino) ethyl]-3- (2-hydroxyphenyl)-1H-pyrazol-1- yl] carbonyl} glycinate ; Ii. 5-cyclopropyl-N-ethyl-3- (2-hydroxy-4-methoxyphenyl)-lH-pyrazole-l- carboxamide; Ij. ethyl-N- {[5-cyclopropyl-3-(2-hydroxy-4-methoxyphenyl)-lH-pyrazol-l- yl] carbonyl} glycinate; Ik. 5-cyclopropyl-N-ethyl-3- H-pyrazole-1- carboxamide; Il. 5-cyclopropyl-N-ethyl-3-(2-hydroxy-5-methylphenyl)-1H-pyrazo le-1-carboxamide ; Im. ethyl-N- { [5-cyclopropyl-3-(2-hydroxy-5-methylphenyl)-lH-pyrazol-1- yl] carbonyl} glycinate; In. N-butyl-5-cyclopropyl-3-(2-hydroxy-4-methoxyphenyl)-1H-pyraz ole-1- carboxamide : Io. N-butyl-5-cyclopropyl-3-(2-hydroxy-5-methylphenyl)-lH-pyrazo le-l-carboxamide ; Ip. N- (3- {l- [ (butylamino) carbonyl]-5-cyclopropyl-lH-pyrazol-3-yl}-4- hydroxyphenyl) isonicotinamide ; Iq. N- (4- {1- [ (butylamino) carbonyl]-5-cyclopropyl-1H-pyrazol-3-yl}-3- hydroxyphenyl) isonicotinamide ; Ir. 3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-N-butyl-5- cyclobutyl-lH-pyrazole-l-carboxamide ; Is. 3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-N-butyl-5- cyclopentyl-1 H-pyrazole-1-carboxamide ; It. N-allyl-5-cyclopropyl-3- (4-fluoro-2-hydroxyphenyl)-lH-pyrazole-l-carboxamide ; Iu. 5- (3, 4-dimethoxyphenyl)-N-ethyl-3- (2-hydroxy-5-methoxyphenyl)-lH-pyrazole-l- carboxamide; Iv. N-allyl-5- [2- (dimethylamino) ethyl]-3- (2-hydroxy-5-methylphenyl)-lH-pyrazole-1- carboxamide ; Iw. 5-[2-(dimethylamino) ethyl]-3-(2-hydroxy-5-methoxyphenyl)-N-(2-phenylethyl)- 1H-pyrazole-1-carboxamide ; <BR> <BR> <BR> Ix. ethyl-N-{[5-(3, 4-dimethoxyphenyl)-3-(2-hydroxy-5-methoxyphenyl)-lH-pyrazol- 1-yl] carbonyl} glycinate ; Iy. 5-cyclopropyl-N-ethyl-3-(4-fluoro-2-hydroxyphenyl)-1H-pyrazo le-1-carboxamide Iz. ethyl-N- [3- (5-chloro-2-hydroxyphenyl)-5-cyclopropyl-lH-pyrazol-l- yl] carbonyl} glycinate; Iaa. 5-cyclopropyl-3- (2-hydroxy-5-methoxyphenyl)-N- (2-phenylethyl)-lH-pyrazole-l- carboxamide; Ibb. 5-cyclopropyl-N-ethyl-3- (2-hydroxyphenyl)-lH-pyrazole-l-carboxamide ; Icc. N-allyl-5- (3, 4-dimethoxyphenyl)-3- (2-hydroxy-5-methoxyphenyl)-lH-pyrazole-l- carboxamide; Idd. N-benzyl-5- (3, 4-dimethoxyphenyl)-3- (2-hydroxy-5-methylphenyl)-lH- pyrazole-1-carboxamide ; Iee. N-allyl-5-cyclopropyl-3-(2-hydroxy-5-methoxyphenyl)-lH-pyraz ole-l- carboxamide; Iff. N-benzyl-5- [2- (dimethylamino) ethyl]-3- (2-hydroxy-5-methoxyphenyl)-lH- pyrazole-1-carboxamide ; Igg. 5-cyclopropyl-3- (2-hydroxy-5-methylphenyl)-N- (2-phenylethyl)-lH- pyrazole-1-carboxamide ; Ihh. 5-[2-(dimethylmaino)ethyl]-N-ethyl-3-(2-hydroxyphenyl)-1H-py razole-1- carboxamide; Iii. Ethyl N- [ (5-cyclobutyl-3- {2-hydroxy-4- [ (3-methoxybenzoyl) amino] phenyl}-1H- pyrazol-l-yl) carbonyl] glycinate and Ijj. Ethyl N- [ (5-cyclopropyl-3- {2-hydroxy-4- [ (3-methoxybenzoyl) amino] phenyl}-lH- pyrazol-l-yl) carbonyl] glycinate.

As formerly indicated, it is a further object of the invention a process for preparing the compounds of formula (I) and pharmaceutically acceptable salts thereof, which process comprises: a) removing Q from a compound of formula (IT) wherein Rl to R7 are as defined above and Q is a hydroxy-phenyl protecting group or a solid support, so as to obtain the compound of formula (I) as defined above and, if desired, b) converting the resultant compound of formula (I) into another compound of formula (I) and/or into a salt or free form thereof.

The above process is an analogy process which can be carried out according to well known methods. It is clear to the person skilled in the art that if a compound of formula (I), prepared according to the above process, is obtained as an admixture of isomers, their separation into the single isomers of formula (I), carried out according to conventional techniques, is still within the scope of the present invention.

Likewise, the salification of a compound of formula (0 or the conversion of its salt into the free compound (I), carried out according to well-known procedures in the art, are still within the scope of the invention.

According to step a) of the process, the removal of Q as defined above from a compound of formula (IT) is preferably carried out under acidic conditions, that is in the presence of suitable acids such as, for instance, hydrochloric, trifluoroacetic, methanesulphonic or p- toluensulphonic acid, as well as by using conventional acid ion exchange resins.

The reaction is carried out under conventional methods, for instance by using a solution of the acid, e. g. a 10% to 100% (v/v) of trifluoroacetic acid in dichlorometane, at a temperature ranging from about 0°C to reflux, and for a suitable time, for instance from about 5 minutes to about 2 hours.

From the above it is clear to the skilled man that the optional conversion of a compound of formula (1) into another compound of formula (I) may be carried out by conventional methods. Likewise, a compound of formula (IT) may be converted into another compound of formula (IV before undergoing deprotection. The conversion of a compound of formula I or II into another different compound of formula I or II may be carried out in several ways, depending on the meanings of the substituents and the presence of other substituents in the molecule.

For example, a conversion can be a hydrolysis, an oxidation, a reduction, a condensation with an appropriate reagent or a combination of these reactions.

Also the optional salification of a compound of formula (I) or the conversion of its salt into the free compound, as well as the separation of a mixture of isomers into the single isomers, may be all carried out by conventional methods.

The compound of formula (II) with a suitable hydroxy-phenyl protecting group or a solid support may be prepared by i) reacting the compound of formula (in) wherein Rl to Rs are as above defined, with a suitable hydroxy-phenyl protecting agent or a solid support, so as to obtain a compound of formula (IV) wherein Rl to Rs are as above defined and Q is the said hydroxy-phenyl protecting group or a solid support; ia) optionally converting the compound of formula (IV) wherein one of Ri to R4 is an amino group into a different compound of formula (IV) wherein one of Rl to R4 is a group of formula NHCOR10, NHCONHR10 or NHSO2R10 wherein Rio is as defined above, by reaction with any one of the compounds of the formula (V), (VI) or (VII) : Rio-COX (V); Rio-N=C=O (VI) ; Rio-S02X' (VII) wherein Rio is as above defined, X is hydroxy or a suitable leaving group and X'is a suitable leaving group; ii) reacting the compound of formula (IV) with a derivative of formula (V2) wherein Ra is a Cl-C6 alkyl group, so as to obtain a compound of formula (IX) wherein Q, Rl to R6 are as above defined; iii) reacting the compound of formula (IX) with hydrazine hydrate so as to obtain the compound of formula (X) wherein Q, Rl to R6 are as above defined; iv) reacting the compound of formula (X) with any one of the compounds of formula (V), (VI), (vit, (XI) or (XII) : Rio-COX (V); Rio-N=C=0 (VI) R10-SO2X' (VII) ; Rio-N=C=S (XI) Rio-OCOX (XII) wherein Rlo, X'and X are as above defined, so as to obtain the compound of formula (II) as defined above.

According to step i) of the process, the compound of formula (in) is reacted with a suitable hydroxy-phenyl protecting agent such as, for instance, benzyl group; or with a solid support such as, for instance, a benzyloxy-polystyrene resin.

Preferably, the oxygen-phenol protecting agent or the solid support is selected from benzyl or a benzyloxy-polystyrene resin.

The reaction is carried out in the presence of a base such as cesium carbonate or potassium carbonate and a salt as tetrabutilamonium iodide or sodium iodide to enhance the solubility of carbonate, in a suitable solvent such as, for instance, N, N-dimethylacetamide or N, N-dimethylformamide, at a temperature ranging from about 0°C to room temperature and for a suitable time, for instance from about 30 minutes to about 96 hours.

According to the optional step ia) of the process, the compound of formula (IV) is reacted with any one of the compounds of formula (V), (VI) or (VII), so as to obtain the corresponding different derivative of formula (IV). In this respect, it is clear to the skilled man that a carboxamido derivative of formula (IV) wherein one of Rl to R4 is NHCORio is obtained through reaction with a compound of formula (V); an ureido derivative of formula (IV) wherein one of Rl to R4 is NHCONHRIO is obtained through reaction with a compound of formula (VI) and a sulphonamido derivative of formula (VIR) wherein one of Rl to R4 is NHSO2RIo is obtained through reaction with a compound of formula (VII).

As formerly indicated, within the compound of formula (V) X is a hydroxy group or a suitable leaving group such as, for instance, a halogen atom. Preferably, in the reaction with a compound of formula (V) X is hydroxy, chlorine or bromine.

The reaction between a compound of formula (IV) and a carboxylic acid derivative of formula (V) wherein X is hydroxy group can be carried out in the presence of a coupling agent such as, for instance, benzotriazol-1-yloxytris (pyrrolidino) phosphonium hexafluorophosphate carbo diimide, 1,3-dicyclohexylcarbodiimide, bromo-tris- pyrrolidino-phosphonium hexafluorophosphate, 1,3-diisopropylcarbodiimide, o-benzotriazol-1-yl-n, n, n', n'-tetramethyluronium tetrafluoroborate, 1- (3- dimethylaminopropyl)-3-ethylcarbodiimide, N-cyclohexylcarbodiimide-N'- propyloxymethyl polystyrene or N-cyclohexylcarbodiimide-N'-methyl polystyrene, in a suitable solvent such as, for instance, dichloromethane, chloroform, tetrahydrofuran, diethyl ether, 1,4-dioxane, acetonitrile, toluene or N, N-dimethylformamide, at a temperature ranging from about-10°C to reflux and for a suitable time ranging from about 30 minutes to about 96 hours.

The said reaction is optionally carried out in the presence of a suitable catalyst, for instance 4-dimethylaminopyridine, or in the presence of a further coupling agent such as N-hydroxybenzotriazole. The reaction between a compound of formula (IV) and a compound of formula (V) can also be carried out through a mixed anhydride method, that is by using an alkyl chloroformate such as ethyl, isobutyl, or isopropyl chloroformate, in the presence of a tertiary base such as triethylamine, N, N-diisopropylethylamine or pyridine, in a suitable solvent such as toluene, dichloromethane, chloroform, tetrahydrofuran, acetonitrile, diethyl ether, 1, 4-dioxane or N, N-dimethylformamide, and at a temperature ranging from about-30°C to room temperature.

The reaction between a compound of formula (IV) and a compound of formula (V) wherein X is a suitable leaving group, for instance chlorine or bromine, can be carried out in the presence of a tertiary base such as triethylamine, N, N-diisopropylethylamine or pyridine, in a suitable solvent such as toluene, dichloromethane, chloroform, diethyl ether, tetrahydrofuran, acetonitrile or N, N-dimethylformamide, and at a temperature ranging from about-10°C to reflux.

The reaction of the compound of formula (IV) with an isocyanate derivative of formula (VI) can be carried out in the presence of a suitable catalyst, for instance 4- dimethylaminopyridine or a tertiary base such as N, N-diisopropylethylamine, in a suitable solvent such as toluene, diethyl ether, tetrahydrofuran, acetonitrile, or N, N- dimethylformamide, and at a temperature ranging from about 20°C to 60°C.

As per step ia) of the process, within the compound of formula (VII) X'is a suitable leaving group such as, for instance, a halogen atom. Preferably, X'is chlorine or bromine.

The reaction between a compound of formula (IV) and a sulphonyl derivative of formula (VII) can be carried out in the presence of a tertiary base such as triethylamine, N, N- diisopropylethylamine or pyridine, in a suitable solvent such as toluene, dichloromethane, chloroform, diethyl ether, tetrahydrofuran, acetonitrile or N, N-dimethylformamide, at a temperature ranging from about-10°C to reflux.

According to step ii) of the process, the compound of formula (V2) is reacted with the compound of formula (IV) under basic conditions, for instance in the presence of a base such as sodium hydryde or potassium ter-butoxide.

The reaction is carried out in a suitable solvent such as, for instance, N, N- dimethylformamide, N, N-dimethylacetamide at a temperature comprised from about 70°C to 100°C and for a suitable time, for instance from about 30 minutes to about 5 hours.

According to step iii) of the process, the reaction between a compound of formula (IX) and hydrazine hydrate is carried out in a suitable solvent such as, for instance, tetrahydrofuran, acetonitrile, 1,4-dioxane, N, N-dimethylacetamide or N, N-dimethylformamide, and at a temperature ranging from about 60°C to 90°C.

According to step iv) of the process, the reaction between a compound of formula (X) and a derivative of formula (V), (VI) or (VII) can be carried out as described in the detailed reaction description under step ia) above.

The reaction of a compound of formula (X) with an or isothiocyanate derivative of formula (XI) can be carried out in the presence of a suitable catalyst, for instance 4- dimethylaminopyridine or a tertiary base such as N, N-diisopropylethylamine, in a suitable solvent such as toluene, diethyl ether, tetrahydrofuran, acetonitrile, or N, N- dimethylformamide, and at a temperature ranging from about 20°C to 60°C. The reaction of a compound of formula (X) with a derivative of formula (XII) can be carried out analogously to that between compound of formula (X) and the derivative of formula (V).

As it will be really appreciated by the man skilled in the art, when preparing the compounds of formula (I) object of the invention, optional functional groups within both the starting materials or the intermediates thereof which could give rise to unwanted side reactions, need to be properly protected according to conventional techniques. Likewise, the conversion of these latter into the free deprotected compounds may be carried out according to known procedures.

The compounds of formula (ILL), (V), (VI), (VIn, (VE), (XI) and (XII) of the process are known or can be prepared according to known methods.

In addition to the above, it is also clear to the skilled man that the compounds of formula (k of the invention can be advantageously prepared by combining the above described reactions in a combinatorial fashion, for example according to solid-phase-synthesis (SPS) techniques, so as to get a combinatorial chemical library of compounds of formula (I).

It is therefore a further object of the invention a library of two or more compounds of formula (I) : wherein Rl to R7 are as defined above.

As such, it is a further object of the present invention a compound of formula (I) which is obtainable, for instance through a combinatorial chemistry technique, as depicted in the following scheme, wherein Pol and Pol-Y are respectively a solid support and its activated form, X, X', Ra, Ri, R2, R3, R4 R5 R6, R7 and Rio are as defined above and the steps are carried out preferably under the reaction conditions set forth herein above. More preferably, one of R2 and R3 represents a group of formula NHCOR10, NHCONHR10 or NHS02Rlo, wherein RIO is as defined above, and the resultant compound has one of the following formula: wherein R6, R7 and RIO are as defined above.

SCHEME 1 OH 0 Pol 0 step i Iz (rv - R w R3 R3 T A . 13 < T ? " ! Pol Y"2 t 4 3 R (IV) (tell) Rio-Cox (V) orR10-N=C=O (VI) stepia or Rlo-S02X' (VI if RZ or R3 is NHZ 0 PolO O OH PolO O stem il R'\ Ru R R 4 \R4 R QRa R3 lA'1 6 T step iii step iv N H am. +N. Pol O i N Rio-COX (V). Ri or Rlo-N=C=O (VI) R6 or Rlo-so2x (VII)/Rs /t/aX or Rro-N=C=S (IX) 4 RZ R4 or Rlo OCOX (XII) 4 ' (X) . (X)/ R7/ OH Nl+N. I Rl R6 R3 (1) 4 R3 (I) Each of the compounds of formula (IV)-obtained from the reaction between the solid support and a derivative of formula (m), as set forth in table I, is optionally reacted with any one of the derivatives of formula (V) or (VI) of table II and IV, and subsequently operating as per the process of the invention by reacting any one of the resultant derivatives of formula (IV) with any one of the derivatives of formula (VIH) as set forth in table III ; reacting the resultant compounds (IX) with hydrazine hydrate and subsequently reacting the resultant compounds (X) with any one of the derivatives of formula (V) or (VI) as set forth in tables II and IV.

Table I: 2-hydroxyacetophenones derivatives of formula (III) 1 4-amino-2-hydroxyacetophenone 2 5-amino-2-hydroxyacetophenone Table II: Acyl chlorides derivatives of formula (V) 1 2-CHLOROBENZOYL CHLORIDE 2 2, 6-DICHLOROBENZOYL CHLORIDE 3 2-METHOXYBENZOYL CHLORIDE 40-TOLUOYL CHLORIDE 53- (TRIFLUOROMETHYL) BENZOYL CHLORIDE 6 4-CHLOROBENZOYL CHLORIDE 7 4-ETHOXYBENZOYL CHLORIDE 8 4-TERT-BUTYLBENZOYL CHLORIDE 9 P-TOLUOYL CHLORIDE 10 4-ETHYLBENZOYL CHLORIDE 11 ISOBUTYRYL CHLORIDE 12 ACETYL CHLORIDE 13 ISOVALERYL CHLORIDE 14 PROPIONYL CHLORIDE 15 CYCLOPROPANECARBONYL CHLORIDE 16 2-FUROYL CHLORIDE 17 THIOPHENE-2-CARBONYL CHLORIDE 18 2-QUINOXALOYL CHLORIDE 19 NICOTINOYL CHLORIDE HYDROCHLORIDE 20 ISONICOTINOYL CHLORIDE HYDROCHLORIDE 21 3, 4-METHYLENEDIOXYBENZOYL CHLORIDE 22 2-ETHYLBUTYRYL CHLORIDE 23 BENZO [B] THIOPHENE-2-CARBONYL CHLORIDE 24 2-CHLORONICOTINOYL CHLORIDE 254- (TRIFLUOROMETHOXY) BENZOYL CHLORIDE 26 ISOXAZOLE-5-CARBONYL CHLORIDE 27 1-METHYLPYRROLE-2-CARBONYL CHLORIDE Table III. Esters derivatives offormula (VIII) 1 ETHYL CYCLOPROPANECARBOXYLATE 2 ETHYL CYCLOBUTANECARBOXYLATE 3 METHYL CYCLOPENTANECARBOXYLATE Table IV : Isocyanates derivatives offormula (VI) 1 ISOPROPYL ISOCYANATE 2 ETHYL ISOCYANATE 3 ALLYL ISOCYANATE 4 N-PROPYL ISOCYANATE 5 ISOCYANATE 6 ISOCYANATE 7 2-METHYLBENZYL ISOCYANATE 8 3-METHYLBENZYL ISOCYANATE 9 4-METHYLBENZYL ISOCYANATE 10 2-CHLOROBENZYL ISOCYANATE 11 4-FLUOROBENZYL ISOCYANATE 12 3, 4-DICHLOROBENZYL ISOCYANATE 13 4-METHOXYBENZYL ISOCYANATE 14 SEC-BUTYL ISOCYANATE 15 2-FLUOROBENZYL ISOCYANATE 16 3-FLUOROBENZYL ISOCYANATE 17 CYCLOPROPYL ISOCYANATE All of the compounds of formula (1) which are prepared according to combinatorial chemistry techniques, for instance as reported in the examples, whenever appropriate in the form of pharmaceutically acceptable salts, are herewith conveniently indicated and defined as"products by process", that is as compounds of formula (I) which are obtainable through a given process.

As such, it is a further object of the present invention a compound of formula (I) which is obtainable, for instance through a combinatorial chemistry technique, by reacting each of the derivatives obtained from a compound of formula (MI), as set forth in table I, with any one of the carboxylic acid derivatives of formula (VET), as set forth in table II, and by subsequently operating as per the process of the invention.

It is a further object of the present invention a compound of formula (I) which is obtainable, for instance through a combinatorial chemistry technique, by reacting each of the derivatives obtained from a compound of formula (m) wherein R2 or R3 is an amino group, as set forth in table I, with any one of the acyl chloride or isocyanate derivatives of formula (V) and (VI), as set forth in tables II and IV, and by subsequently operating as per the process of the invention.

Pharmacology The compounds of formula (I) are active as protein kinase inhibitors and are therefore useful, for instance, to restrict the unregulated proliferation of tumor cells.

In therapy, they may be used in the treatment of various tumors such as, for instance, carcinomas, e. g. mammary carcinoma, lung carcinoma, bladder carcinoma, colon carcinoma, ovary and endometrial tumors, sarcomas, e. g. soft tissue and bone sarcomas, and the hematological malignancies such as, e. g. , leukemias.

In addition, the compounds of formula (I) are also useful in the treatment of other cell proliferative disorders such as psoriasis, vascular smooth cell proliferation associated with atherosclerosis and post-surgical stenosis and restenosis and in the treatment of Alzheimer's disease.

The inhibiting activity of putative protein kinase inhibitors and the potency of selected compounds was determined through a method of assay based on the use of the MultiScreen-PH 96 well plate (Millipore), in which a phosphocellulose filter paper was placed at each well bottom allowing binding of positive charged substrate after a washing/filtration step.

When a radioactivity labeled phosphate moiety was transferred by the ser/threo kinase to the filter-bound histone, light emitted was measured in a scintillation counter.

Inhibition assay of cdk2/Cvclin A activity Kinase reaction: 1. 5, uM histone H1 substrate, 25, uM ATP (0.2 uCi P330-ATP), 30 ng of baculovirus co-expressed cdk2/Cyclin A, 10 pM inhibitor in a final volume of 100 las buffer (TRIS Hui 10 mM pH 7.5, MgCl2 10 mM, 7.5 mM DTT) were added to each well of a 96 U bottom well plate. After 10 min at 37 °C incubation, reaction was stopped by 20 , 1 EDTA 120 mM.

Capture: 100 p1 were transferred from each well to MultiScreen plate, to allow substrate binding to phosphocellulose filter. Plates were then washed 3 times with 150 µl/well PBS Ca++/Mg++ free and filtered by MultiScreen filtration system.

Detection: filters were allowed to dry at 37°C, then 100 ul/well scintillant were added and 33P labeled histone H1 was detected by radioactivity counting in the Top-Count instrument.

Results: data were analyzed and expressed as % inhibition referred to total activity of enzyme (=100%).

All compounds showing inhibition > 50 % were further analyzed in order to study and define potency (IC50) as well as the kinetic-profile of inhibitor through Ki calculation.

IC50 determination: the protocol used was the same described above, where inhibitors were tested at different concentrations ranging from 0.0045 to 10 suM. Experimental data were analyzed by the computer program GraphPad Prizm using the four parameter logistic equation : y = bottom+ (top-bottom)/ (1+10^ ( (logIC50-x) *slope)) where x is the logarithm of the inhibitor concentration, y is the response; y starts at bottom and goes to top with a sigmoid shape.

Ki calculation: either the concentration of ATP and histone H1 substrate were varied: 4,8, 12,24, 48 uM for ATP (containing proportionally diluted P33y-ATP) and 0.4, 0.8, 1.2, 2.4, 4.8 pM for histone were used in absence and presence of two different, properly chosen inhibitor concentrations.

Experimental data were analyzed by the computer program"SigmaPlot"for Ki determination, using a random bireactant system equation: Vmax (A) (B) <BR> <BR> <BR> <BR> aKAKB<BR> <BR> <BR> <BR> <BR> <BR> aKAKB 1+ (A+ (B) + (A) (B) KA KB aKAKB where A=ATP and B=histone H1.

In addition the selected compounds have been characterized on a panel of ser/threo kinases strictly related to cell cycle (cdk2/cyclin E, cdk1/cyclin Bl, cdk4/Cyclin D1), and also for specificity on MAPK, PKA, EGFR, IGF1-R, Cdc7/dbf4 and aurora-2.

Inhibition assay of cdk2/Cyclin E activity Kinase reaction: 1. 5 µM histone H1 (Sigma # H-5505) substrate, 25 uM ATP (0.2 OCi P33y-ATP), 15 ng of baculovirus co-expressed cdk2/GST-Cyclin E, suitable concentrations of inhibitor in a final volume of 100 1ll buffer (TRIS HCl 10 mM pH 7.5, MgCl2 10 mM, 7.5 mM DTT+ 0. 2mg/ml BSA) were added to each well of a 96 U bottom well plate. After 10 min at 37 °C incubation, reaction was stopped by 20 Uul EDTA 120 mM.

Capture: 100 J. l were transferred from each well to MultiScreen plate, to allow substrate binding to phosphocellulose filter. Plates were then washed 3 times with 150 Ol/well PBS Ca++/Mg++ free and filtered by MultiScreen filtration system.

Detection: filters were allowed to dry at 37°C, then 100 µl/well scintillant were added and 33P labeled histone H1 was detected by radioactivity counting in the Top-Count instrument.

Inhibition assay of cdkl/Cyclin Bl activity Kinase reaction: 1.5 µM histone Hl (Sigma # H-5505) substrate, 25 elm ATP (0.2 µCi P33γ-ATP), 30 ng of baculovirus co-expressed cdkl/Cyclin B1, suitable concentrations of inhibitor in a final volume of 100 tl buffer (TRIS Hic110 mM pH 7.5, MgCl2 10 mM, 7.5 mM DTT+ 0.2mg/ml BSA) were added to each well of a 96 U bottom well plate. After 10 min at 37 °C incubation, reaction was stopped by 20 al EDTA 120 mM.

Capture: 100 u. l were transferred from each well to MultiScreen plate, to allow substrate binding to phosphocellulose filter. Plates were then washed 3 times with 150 Ill/well PBS Ca/Mg free and filtered by MultiScreen filtration system.

Detection: filters were allowed to dry at 37°C, then 100 µl/well scintillant were added and 33P labeled histone Hl was detected by radioactivity counting in the Top-Count instrument.

Inhibition assay cdk4/Cyclin Dl activity Kinase reaction: 0,4 uM, uM mouse GST-Rb (769-921) (# sc-4112 from Santa Cruz) substrate, 10, uM ATP (0.5 LCi P33y-ATP), 100 ng of baculovirus expressed GST- cdk4/GST-Cyclin D1, suitable concentrations of inhibitor in a final volume of 50 p. 1 buffer (TRIS Hui 10 mM pH 7.5, MgC12 10 mM, 7.5 mM DTT+ 0.2mg/ml BSA) were added to each well of a 96 U bottom well plate. After 40 min at 37 °C incubation, reaction was stopped by 20 ul EDTA 120 mM.

Capture: 60 1ll were transferred from each well to MultiScreen plate, to allow substrate binding to phosphocellulose filter. Plates were then washed 3 times with 150 Ol/well PBS Ca+F/MgX free and filtered by MultiScreen filtration system.

Detection: filters were allowed to dry at 37°C, then 100 µl/well scintillant were added and 33P labeled Rb fragment was detected by radioactivity counting in the Top-Count instrument.

Inhibition assay of MAPK activity Kinase reaction: 10 µM MBP (Sigma # M-1891) substrate, 25 µM ATP (0.2 µCi P33γ- ATP), 25 ng of bacterially expressed GST-MAPK (Upstate Biotechnology # 14-173), suitable concentrations of inhibitor in a final volume of 100 ul buffer (TRIS HCl 10 mM pH 7.5, MgC12 10 mM, 7.5 mM DTT + 0.1 mg/ml BSA) were added to each well of a 96 U bottom well plate. After 15 min at 37 °C incubation, reaction was stopped by 20 EDTA 120 mM.

Capture: 100 µl were transferred from each well to MultiScreen plate, to allow substrate binding to phosphocellulose filter. Plates were then washed 3 times with 150 µl/well PBS Ca++/Mg-'"+ free and filtered by MultiScreen filtration system.

Detection: filters were allowed to dry at 37°C, then 100 µl/well scintillant were added and 33P labeled MBP was detected by radioactivity counting in the Top-Count instrument.

Inhibition assay of PKA activity Kinase reaction: 10 iM histone Hl (Sigma # H-5505) substrate, 10 I ATP (0.2 u. Ci P33y-ATP), 1U of bovine heart PKA (Sigma # 2645), suitable concentrations of inhibitor in a final volume of 100 al buffer (TRIS HCl 10 mM pH 7.5, MgCl2 10 mM, 7.5 mM DTT+ 0.2mg/ml BSA) were added to each well of a 96 U bottom well plate. After 5 min at 37 °C incubation, reaction was stopped by 20 p1 EDTA 120 mM.

Capture : 100 pi were transferred from each well to MultiScreen plate, to allow substrate binding to phosphocellulose filter. Plates were then washed 3 times with 150 Ill/well PBS Ca+F/Mgw free and filtered by MultiScreen filtration system.

Detection: filters were allowed to dry at 37°C, then 100 pl/well scintillant were added and 33P labeled histone H1 was detected by radioactivity counting in the Top-Count instrument.

Inhibition assay of EGFR activity Kinase reaction: 25 nM in house biotinylated PolyGluTyr (Sigma # 0275) substrate, 2,5 pM ATP (0. 3 µCi P33γ-ATP), 80 ng baculovirus expressed GST-EGFR, suitable concentrations of inhibitor in a final volume of 100 pi buffer (Hepes 50 mM pH 7,5, MnCl2-MgCl2 3mM, 1mM DTT + 3 µM NaVO3, 0.1 mg/ml BSA) were added to each well of a 96 U bottom well plate. After 5 min. at 37 °C incubation, reaction was stopped by20plEDTA120mM.

Capture: 100 pi were transferred from each well to streptavidin-Flashplate, to allow biotinylated-substrate binding to plate. Plates were then washed 3 times with 150 pl/well PBS Ca++/Mg+ free.

Detection: radioactivity counting in the Top-Count instrument.

Inhibition assay of IGF1-R activity The inhibition assay of IGF1-R activity was performed according to the following protocol.

Kinase reaction: 10 pM biotinylated MBP (Sigma cat. &num M-1891) substrate, 0-20 LM inhibitor, 6 LM cold ATP, 2 nM 33P-ATP, and 22.5 ng IGF1-R (pre-incubated for 30 min at room temperature with cold 60, uM cold ATP) in a final volume of 30 pi buffer (50 mM HEPES pH 7.9, 3 mM MnCl2, 1 mM DTT, 3 µM NaVO3) were added to each well of a 96 U bottom well plate. After incubation for 35 min at room temperature, the reaction was stopped by addition of 100 µl PBS buffer containing 32 mM EDTA, 500 pM cold ATP, 0.1% Triton X100 and lOmg/ml streptavidin coated SPA beads. After 15 min incubation, 110 pi of suspension were withdrawn and transferred into 96-well OPTIPLATEs containing 100 pi of 5M CsCl. After 4 hours, the plates were read for 2 min in a Packard TOP-Count radioactivity reader.

Results: Experimental data were analyzed with the program GraphPad Prizm.

In addition, the inhibiting activity of putative protein kinase inhibitors and the potency of selected compounds was also determined through a method of assay based on the use of a SPA (Scintillation Proximity Assay) 96 well plate assay. The assay is based on the ability of streptavidin coated SPA beads to capture a biotinylated peptide derived from a phosphorylation site of histone.

When a radioactivity labeled phosphate moiety was transferred by the ser/threo kinase to the biotinylated histone peptide, light emitted was measured in a scintillation counter.

Inhibition assay of cdk5/p25 activity The inhibition assay of cdk5/p25 activity was performed according to the following protocol.

Kinase reaction: 1.0 uM biotinylated histone peptide substrate, 0.25 uCi P33g-ATP, 4 nM cdk5/p25 complex, 0-100 uM inhibitor in a final volume of 100 p. l buffer (Hepes 20 mM pH 7.5, MgC12 15 mM, 1 mM DTT) were added to each well of a 96 U bottom well plate. After 20 min at 37 °C incubation, the reaction was stopped by the addition of 500 ug SPA beads in phosphate-buffered saline containing 0. 1% Triton X-100, 50 uM ATP and 5 mM EDTA. The beads were allowed to settle, and the radioactivity incorporated in the 33P-labelled peptide was detected in a Top Count scintillation counter.

Results: Data were analyzed and expressed as % Inhibition using the formula : 1 OOX (1- (Unknown-Bkgd)/ (Enz. Control-Bkgd)) IC50 values were calculated using a variation of the four parameter logistics equation: Y 100/[1 + 10 ^ ( (LogEC50-X) *Slope) ] Where X =log (uM) and Y = % Inhibition.

Inhibition assay of Cdc7/dbf4 activity The inhibition assay of Cdc7/dbf4 activity was performed according to the following protocol.

The Biotin-MCM2 substrate is trans-phosphorylated by the Cdc7/Dbf4 complex in the presence of ATP traced with 733-ATP. The phosphorylated Biotin-MCM2 substrate is then captured by Streptavidin-coated SPA beads and the extent of phosphorylation evaluated by ß counting.

The inhibition assay of Cdc7/dbf4 activity was performed in 96 wells plate according to the following protocol.

To each well of the plate were added : -10 111 substrate (biotinylated MCM2,6 uM final concentration) - 10 p. 1 enzyme (Cdc7/Dbf4,12. 5 nM final concentration) all test compound (12 increasing concentrations in the nM to tM range to generate a dose-response curve) -10 pL of a mixture of cold ATP (10 pM final concentration) and radioactive ATP (1/2500 molar ratio with cold ATP) was then used to start the reaction which was allowed to take place at 37°C.

Substrate, enzyme and ATP were diluted in 50 mM HEPES pH 7.9 containing 15 mM MgCl2, 2 mM DTT, 3 tM NaV03,2mM glycerophosphate and 0. 2mg/ml BSA. The solvent for test compounds also contained 10% DMSO.

After incubation for 20 minutes, the reaction was stopped by adding to each well 100 0 1 of PBS pH 7. 4 containing 50 mM EDTA, 1 mM cold ATP, 0.1% Triton X100 and 10 mg/ml streptavidin coated SPA beads.

After 15 minutes of incubation at room temperature to allow the biotinylated MCM2- streptavidin SPA beads interaction to occur, beads were trapped in a 96 wells filter plate (UnifilterR GFBTM) using a Packard Cell Harvester (Filtermate), washed with distilled water and then counted using a Top Count (Packard).

Counts were blank-subtracted and then the experimental data (each point in triplicate) were analyzed for IC50 determination using a non-linear regression analysis (Sigma Plot).

Inhibition assay of aurora-2 activity The inhibiting activity and the potency of selected compounds was determined through a method of assay based on the use of the streptavidin scintillation proximity assay beads (amershampharmacia biotech) run in a 96 well plates. At the end of the reaction, the biotinylated peptide substrate was captured with the beads and subsequently allowed to stratify using CsC12.

When a radioactivity labeled phosphate moiety was transferred by the kinase to the beads- bound peptide, light emitted was measured in a scintillation counter.

The inhibition assay of Aurora-2 activity was performed in 96 wells plate according to the following protocol.

Kinase reaction: 8 uM biotinylated peptide (4 repeats of LRRWSLG), 10 uM ATP (0. 5 uCi P33g-ATP), 10 nM Aurora2,10 inhibitor in a final volume of 60 p buffer (HEPES 50 mM pH 7.0, MgCl2 10 mM, 1 mM DTT, 0.125 mg/ml BSA, 3, uM orthovanadate) were added to each well of a 96 U bottom well plate. After 30 minutes at room temperature incubation, reaction was stopped and biotinylated peptide captured by adding 100 jj. l of bead suspension.

Stratification : 100 ul of CsC12 7.5 M were added to each well and let stand one hour before radioactivity was counted in the Top-Count instrument.

Results: data were analyzed and expressed as % inhibition referred to total activity of enzyme (=100%).

All compounds showing inhibition > 60 % were further analyzed in order to study the potency of the inhibitor through IC50 calculation.

The protocol used was the same described above, except that serial dilution of the inhibitor was used. Experimental data were fitted by nonlinear regression using the following equation: With vb as the baseline velocity, v as the observed reaction velocity, vo as the velocity in the absence of inhibitors, and [I] as the inhibitor concentration.

The compounds of formula (I) of the present invention, suitable for administration to a mammal, e. g. to humans, can be administered by the usual routes and the dosage level depends upon the age, weight, conditions of the patient and the administration route.

For example, a suitable dosage adopted for oral administration of a compound of formula (I) may range from about 10 to about 500 mg pro dose, from 1 to 5 times daily.

The compounds of the invention can be administered in a variety of dosage forms, e. g. orally, in the form of tablets, capsules, sugar or film coated tablets, liquid solutions or suspensions; rectally in the form of suppositories; parenterally, e. g. intramuscularly, or by intravenous and/or intrathecal and/or intraspinal injection or infusion.

In addition, the compounds of the invention can be administered either as single agents or, alternatively, in combination with known anticancer treatments such as radiation therapy or chemotherapy regimen in combination with cytostatic or cytotoxic agents, antibiotic- type agents, alkylating agents, antimetabolite agents, hormonal agents, immunological agents, interferon-type agents, cyclooxygenase inhibitors (e. g. COX-2 inhibitors), metallomatrixprotease inhibitors, telomerase inhibitors, tyrosine kinase inhibitors, anti- growth factor receptor agents, anti-HER agents, anti-EGFR agents, anti-angiogenesis agents, farnesyl transferase inhibitors, ras-raf signal transduction pathway inhibitors, cell cycle inhibitors, other cdks inhibitors, tubulin binding agents, topoisomerase I inhibitors, topoisomerase II inhibitors, and the like.

As an example, the compounds of the invention can be administered in combination with one or more chemotherapeutic agents such as, for instance, exemestane, formestane, anastrozole, letrozole, fadrozole, taxane, taxane derivatives, encapsulated taxanes, CPT- 11, camptothecin derivatives, anthracycline glycosides, e. g. , doxorubicin, idarubicin, epirubicin, etoposide, navelbine, vinblastine, carboplatin, cisplatin, estramustine, celecoxib, tamoxifen, raloxifen, Sugen SU-5416, Sugen SU-6668, Herceptin, and the like, optionally within liposomal formulations thereof.

If formulated as a fixed dose, such combination products employ the compounds of this invention within the dosage range described above and the other pharmaceutically active agent within the approved dosage range.

Compounds of formula (I) may be used sequentially with known anticancer agents when a combination formulation is inappropriate.

It is therefore a further object of the invention a product or kit comprising the compound of formula (I) of the invention and one or more chemotherapeutic agents for simultaneous, separate or sequential use in anticancer therapy or for the treatment of cell proliferative disorders.

The present invention also includes pharmaceutical compositions comprising an effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof in association with a pharmaceutically acceptable excipient, carrier or diluent.

The pharmaceutical compositions containing the compounds of the invention are usually prepared following conventional methods and are administered in a pharmaceutically suitable form.

For example, the solid oral forms may contain, together with the active compound, diluents, e. g. lactose, dextrose, saccharose, sucrose, cellulose, corn starch or potato starch ; lubricants, e. g. silica, talc, stearic, magnesium or calcium stearate, and/or polyethylene glycols ; binding agents, e. g. starches, arabic gum, gelatine, methylcellulose, carboxymethylcellulose or polyvinyl pyrrolidone ; disaggregating agents, e. g. a starch, alginic, alginates or sodium starch glycolate; effervescing mixtures; dyestuffs ; sweeteners; wetting agents such as lecithin, polysorbates, laurylsulphates; and, in general, non-toxic and pharmacologically inactive substances used in pharmaceutical formulations. Said pharmaceutical preparations may be manufactured in known manner, for example, by means of mixing, granulating, tabletting, sugar-coating, or film-coating processes.

The liquid dispersions for oral administration may be e. g. syrups, emulsions and suspensions.

The syrups may contain as carrier, for example, saccharose or saccharose with glycerine and/or mannitol and/or sorbitol.

The suspensions and the emulsions may contain as carrier, for example, a natural gum, agar, sodium alginate, pectin, methylcellulose, carboxymethylcellulose, or polyvinyl alcohol.

The suspension or solutions for intramuscular injections may contain, together with the active compound, a pharmaceutically acceptable carrier, e. g. sterile water, olive oil, ethyl oleate, glycols, e. g. propylene glycol, and, if desired, a suitable amount of lidocaine hydrochloride. The solutions for intravenous injections or infusions may contain as carrier, for example, sterile water or preferably they may be in the form of sterile, aqueous, isotonic saline solutions or they may contain as a carrier propylene glycol.

The suppositories may contain together with the active compound a pharmaceutically acceptable carrier, e. g. cocoa butter, polyethylene glycol, a polyoxyethylene sorbitan fatty ester surfactant or lecithin.

EXAMPLES The following examples are herewith intended to better illustrate the present invention without posing any limitation to it.

General Methods Flash chromatografy was performed on silica gel (Merck grade 9385, 60A). SPE (Solid Phase Extraction) was performed using prepacked cartridges with silica gel available from several vendors. FT-IR was obtained using a Perkin-Elmer spectrophotometer with the micropellets. HPLC/MS was performed on a Waters X Terra RP 18 (4.6 x 50 mm, 3. 5 urn) column using a Waters 2790 HPLC system equipped with a 996 Waters PDA detector and a Micromass mod. ZQ single quadrupole mass spectrometer, equipped with an electrospray (ESI) ion source. Mobile phase A was ammonium acetate 5 mM buffer (pH 5.5 with acetic acid/acetonitrile 95: 5), and Mobile phase B was H2O/acetonitrile (5: 95).

Gradient from 10 to 90% B in 8 minutes, hold 90% B 2 min. UV detection at 220 nm and 254 nm. Flow rate 1 ml/min. Injection volume 10 kl. Full scan, mass range from 100 to 800 amu. Capillary voltage was 2.5 KV ; Source temp. was 120°C ; Cone was 10 V.

Retention Times (HPLC r. t. ) are given in minutes at 220 nm or 254 nm. Mass are given as m/z ratio.

When necessary compounds have been purified by Preparative HPLC on a Waters Symmetry C18 (19 x 50 nun, 5um) column using a Waters preparative HPLC 600 equipped with a 996 Waters PDA detector and a Micromass mod. ZMD single quadrupole mass spectrometer, electrospray ionisation, positive mode. Mobile phase A was water 0. 01% TFA, and Mobile phase B was acetonitrile. Gradient from 10 to 90% B in 8 min, hold 90% B 2 min. Flow rate 20 ml/m.

IH-NMR spectroscopy was performed on a Mercury VX 400 operating at 400.45 MHz equipped with a 5mm double resonance probe (1H {15N-31P} ID_PFG Varian).

Example 1 1- [4-Amino-2- (4-benzyloxy-benzyloxy)-phenyl]-ethanone To 0. 83 mmol of resin 2 (1 g) in 15 ml of DMA were added 6.64 mmol of 4-amino-2- hydroxyacetophenone (8 eq 1.0 g), 4.15 mmol of cesium carbonate (5 eq 1.35 g), and 0.83 mmol of tetrabutylammonium iodide (1 eq 0.3 g). The slurry was left under magnetic stirring for 24 h at room temperature, then the resin was filtered, washed with DMF (2x), MeOH, THF, MeOH, DCM (3x) and dried in vacuo to give 1.1 g of resin.

FT-IRKBrmicropellet O cm~l : 1675 (C=O, s, st).

Example 2 N- [4-Acetyl-3- (4-benzyloxy-benzyloxy-polystyrene)-phenyl]-4-methoxy-benzam ide 1- [4-Amino-2- (4-benzyloxy-benzyloxy)-phenyl]-ethanone (0.166 mmol, 0.2 g) was suspended with 0.5 ml of DiPEA (excess), 10 mg of DMAP in 5 ml of DCM. To the slurry was added under argon, 0.49 mmol of p-anisoyl chloride (3 eq, 85 mg). The mixture was stirred at room temperature for 18h. The slurry was filtered and the resin washed with DMF, MeOH, DMF, MeOH, THF, MeOH, DCM (3x). The resin was dried under vacuum to give 0.22g of product.

FT-IR KBr micropellet Cl cm-1 : 1679 (C=O, s, b, st).

Example 3 N- [4-Acetyl-3- (4-benzyloxy-benzyloxy-polystyrene)-phenyl]-4-methoxy-benzam ide N- [4-Acetyl-3- (4-benzyloxy-benzyloxy-polystyrene)-phenyl]-4-methoxy-benzam ide, (0.166 mmol, 0.2 g) was suspended in a solution of 3.32 mmol of ethyl cyclopropyl carboxylate (20 eq, 568 mg) in 5 ml of DMA. To the slurry was added under argon, 4.98 mmol of sodium hydride (30 eq, 199 mg as 60% dispersion in paraffin oil). The mixture was heated under stirring at 90° for lh. The slurry was filtered and the resin washed with DMF, AcOH 20%, H20, DMF, MeOH, THF, MeOH, DCM (3x).

The resin was dried under vacuum and 0.22 g was obtained.

FT-llt KBr micropellet # cm-1: 1603 (C=O, s, b, st).

Example 4 <BR> <BR> N- [3- (4-Benzyloxy-benzyloxypolystyrene)-4- (3-cyclopropyl-3-oxo-propionyl)-phenyl]-<BR> <BR> <BR> <BR> <BR> <BR> 4-methoxy-benzamide N- [3- (4-Benzyloxy-benzyloxypolystyrene)-4- (3-cyclopropyl-3-oxo-propionyl)-phenyl]-4- methoxy-benzamide (0.166 mmol, 0.2 g) was swelled in a solution of 16 mmol of hydrazine hydrate (100 eq), in 3 ml of DMA. The suspension was heated at 80° under magnetic stirring overnight. The resin was filtered and washed with DMF (2x), MeOH, THF, MeOH, DCM (3x) consecutively.

The resin was dried under vacuum and 0.21 g was obtained.

FT-IR KBrmicropellet D cm'' : 3442 (N-H, b, st).

As further analytical investigation an aliquot of resin was incubated with TFA/DCM 50% for one hour, then filtered off and the solution was evaporated under nitrogen to dryness.

We obtained from 5 mg of resin (loading 0. 83mMol/g) 0.76 mg of N- [4- (5-Cyclopropyl- lH-pyrazol-3-yl)-3-hydroxy-phenyl]-4-methoxy-benzamide. The final product was obtained in 80% yield with 95% HPLC purity (according to HPLC analysis at 220nm).

[M+H] + = 350 [M] -= 348, HPLC r. t. 5. 35.'H-NMR (DMSO-d6), (ppm) : 10.06 (s, 1H), 9.79 (s, 1H), 7.94 (d, 2H), 7.73 (d, 1H), 7.55 (s, 1H), 7.26 (d, 1H), 7.04 (d, 2H), 6.60 (s, 1H), 3. 83 (s, 3H), 2. 82 (m, 1H), 1.02 (m, 2H), 0.74 (m, 2H).

Example 5 3- [2- (4-Benzyloxy-benzyloxypolystyrene)-4- (4-methoxy-benzoylamino)-phenyl]-5- cyclopropyl-pyrazole-1-carboxylic acid butylamide N- [3- (4-Benzyloxy-benzyloxypolystyrene)-4- (5-cyclopropyl-lH-pyrazol-3-yl)-phenyl]-4- methoxy-benzamide (0.124 mmol 0.15 g) was suspended in a solution of 0.124 mmol of DiPEA (1 eq, 22 p. L) in 3 ml of toluene and to the suspension was added 1.2 mmol of n- butylisocyanate (10 eq, 100 uL) and stirred at 60° overnight. The resin was filtered and washed with DMF (2x), MeOH, THF, MeOH, DCM (3x) and dried in vacuo, to obtain 0.124 mg of resin.

FT-IR KBr micropellet D cm-1: 3442 (N-H, b, st, ), 1745 (C=O uerea, s, st) 1679 (C=O amide, s, st,).

Example 6 5-Cyclopropyl-3-[2-hydroxy-4-(4-methoxy-benzoylamino) phenyl]-pyrazole-1- carboxylic acid butylamide 0.124 mmol, of 3- [2- (4-Benzyloxy-benzyloxypolystyrene)-4- (4-methoxy-benzoylamino)- phenyl]-5-cyclopropyl-pyrazole-1-carboxylic acid butylamide resin were swelled in 2 ml of 50% TFA in DCM. The resulting suspension was gently stirred or shaken at 22°C for lh. The resin was filtered and washed with DCM, the solution was collected in a test tube and evaporated to dryness under nitrogen.

We obtained 20 mg (yield 40%) of product. LC/MS analysis showed 50 % purity @ 254 nm. After filtration through 250 mg of silica gel packed in a 3 ml cartridge was recovered 11. 5 mg.

LC/MS analysis gave 90 % of purity HPLC r. t. 8.24 [M+H] + =449, [M-H] -= 447.

1H-NMR (DMSO-d6), (ppm) : 10.06 (s, 1H), 9.79 (s, 1H), 8.56 (t, 1H), 7.94 (d, 2H), 7.73 (d, 1H), 7.55 (s, 1H), 7.26 (d, 1H), 7.04 (d, 2H), 6.60 (s, 1H), 3. 83 (s, 3H), 3.25 (m, 2H), 2.82 (m, 1H), 1.54 (m, 2H), 1.33 (m, 2H), 1.02 (m, 2H), 0.91 (t, 3H), 0.74 (m, 2H).

By working in an analogous way and by using the appropriate 2- hydroxyacetophenones derivatives, the appropriate carboxylic ester derivatives and the appropriate isocyanates derivatives, the following compounds were prepared: N-ethyl-3- H-pyrazole-l-carboxamide, [M+H] + = 309. IH-NMR (DMSO d6) diagnostic signals (ppm): 8. 73 (d, 2H), 7.20 (dd, 1H), 6.92 (d, 1H), 6.91 (dd, 1H), 2. 81 (q, 2H), 1.12 (t, 3H).

5-Cyclopropyl-3- (2-hydroxyphenyl)-N-propyl-lH-pyrazole-l-carboxamide, [M+H] + = 285. 1H-NMR (DMSO d6) diagnostic signals (ppm): 9.78 (s, 1H), 8. 67 (t, 1H), 7. 78 (d, 1H), 7.21 (m, 1H), 6.84 (m, 2H), 6.63 (s, 1H), 3.22 (m, 2H), 2.75 (m, 1H), 1.58 (m, 1H), 1. 01 (m, 2H), 0. 89 (t, 3H), 0.74 (m, 2H).

Ethyl N-{[5-cyclopropyl-3-(2-hydroxyphenyl)-lH-pyrazol-1-yl] carbonyl} glycinate [M+H] + = 330. IH-NMR (DMSO d6) diagnostic signals (ppm): 9.78 (s, 1H), 8.95 (t, 1H) 7.8 (d, 1H), 7.22 (dd, 1H), 6.93 (m, 2H), 6.68 (s, 1H), 4.15 (q, 2H), 4.01 (d, 2H), 2.73 (m, IH), 1.21 (t, 3H), 1.01 (m, 2H), 0.76 (m, 2H).

N-allyl-5-cyclopropyl-3- (2-hydroxyphenyl)-1H-pyrazole-1-carboxamide, [M+H] + =284.'H-NMR (DMSO d6) diagnostic signals (ppm): 9. 85 (s, 1H), 8.82 (t, 1H), 7.81 (d, 1H), 7.2 (dd, 1H), 6.92 (m, 2H), 6.65 (s, 1H), 5.92 (m, 1H) 5.2 (d, 1H), 5.12 (d, 1H), 3.88 (dd, 2H), 2.75 (m, 1H), 1.02 (m, 2H), 0.75 (m, 2H).

N-cyclohexyl-5-cyclopropyl-3- (2-hydroxyphenyl)-lH-pyrazole-1-carboxamide [M+H] + = 326. 1H-NMR (DMSO d6) diagnostic signals (ppm): 9.88 (s, 1H), 8.23 (d, 1H), 7.79 (d, 1H), 7.2 (dd, 1H), 6.91 (d, 1H), 6. 87 (dd, 1H), 6.62 (s, 1H), 3.62 (m, 1H), 2.75 (m, 1H), 1. 82-1. 15 (m, 10H), 1.02 (m, 2H), 0.75 (m, 2H). <BR> <BR> <BR> <BR> <P>5-Cyclopropyl-N-ethyl-3-(2-hydroxy-4-{[3-(trifluoro methyl) benzoyl] amino} phenyl)-<BR> <BR> <BR> <BR> <BR> <BR> IH-pyrazole-l-carboxamide, [M+H] + = 459.'H-NMR (DMSO d6) diagnostic signals (ppm): 10.41 (s, 1H), 9.82 (s, 1H), 8.57 (t, 1H), 8.25 (s, 1H), 8.22 (d, 1H), 7.95 (d, 1H), 7.80 (d, 1H), 7.57 (s, 1H), 7.27 (d, 1H), 6.62 (s, 1H), 3. 28 (m, 2H), 2.75 (m, 1H), 1.16 (t, 3H), 1.02 (m, 2H), 0.75 (m, 2H).

Ethyl-N-{[5-[2-(dimethylamino) ethyl]-3-(2-hydroxyphenyl)-lH-pyrazol-1- yl]carbonyl} glycinate, [M+H] + = 361 IH-NMR (DMSO d6) diagnostic signals (ppm): 9.02 (s, 1H), 9.05 (t, 1H), 7.90 (d, 1H), 7.22 (dd, 1H), 6.97 (s, lHl), 6.95 (d, 1H), 6.9 (dd, 1H), 4.13 (q, 2H), 4.02 (d, 2H), 3.41 (bs, 4H), 2.83 (s, 6H), 1.21 (t, 3H). <BR> <BR> <BR> <BR> <P>5-Cyclopropyl-N-ethyl-3-(2-hydroxy-4-methoxyphenyl) -lH-pyrazole-1-carboxamide, [M+H] + = 302. lH-NMR (DMSO d6) diagnostic signals (ppm): 9.91 (s, 1H), 8. 55 (t, 1H), 7.67 (d, 1H), 6.56 (s, 1H), 6.46 (m, 2H), 3.74 (s, 3H), 3. 22 (m, 2H), 2.75 (m, 1H), 1.15 (t, 3H), 1.02 (m, 2H), 0.75 (m, 2H).

Ethyl-N-{[5-cyclopropyl-3-(2-hydroxy-4-methoxyphenyl)-lH- pyrazol-1- yl] carbonyl} glycinate, [M+H] + = 360.'H-NMR (DMSO d6) diagnostic signals (ppm): 9.89 (s, 1H), 8.94 (t, 1H), 7.66 (d, 1H), 6.61 (s, 1H), 6.48 (m, 2H), 4.13 (q, 2H), 4.02 (d, 2H), 3.74 (s, 3H), 2.75 (m, 1H), 1.21 (t, 3H), 1.02 (m, 2H), 0.75 (m, 2H). <BR> <BR> <BR> <BR> <P>5-Cyclopropyl-N-ethyl-3-(2-hydroxy-5-methoxyphenyl) -lH-pyrazole-1-carboxamide, [M+H] + = 302. lH-NMR (DMSO d6) diagnostic signals (ppm): 9.33 (s, 1H), 8. 58 (t, 1H), 7.34 (d, 1H), 6.82 (m, 2H), 6.68 (s, 1H), 3.72 (s, 3H), 3.22 (m, 2H), 2.74 (m, 1H), 1.15 (t, 3H), 1.02 (m, 2H), 0.75 (m, 2H). <BR> <BR> <BR> <P>5-Cyclopropyl-N-ethyl-3- (2-hydroxy-5-methylphenyl)-lH-pyrazole-l-carboxamide, [M+H] + = 286. IH-NMR (DMSO d6) diagnostic signals (ppm): 9.33 (s, 1H), 8.57 (t, 1H), 7.34 (d, 1H), 6.81 (m, 2H), 6.68 (s, 1H), 3.22 (m, 2H), 2.74 (m, 1H), 2.22 (s, 3H), 1.15 (t, 3H), 1.02 (m, 2H), 0.75 (m, 2H).

Ethyl-N-{[5-eyelopropyl-3-(2-hydroxy-5-methylphenyl)-lH-pyra zol-1- yl] carbonyl} glycinate, [M+H] + = 344. 1H-NMR (DMSO d6) diagnostic signals (ppm): 9.52 (s, 1H), 8. 58 (t, 1H), 7.59 (d, 1H), 7.02 (d, 1H), 6. 81 (d, 1H), 6.62 (s, 1H), 3.22 (m, 2H), 2.75 (m, 1H), 2.23 (s, 3H), 1.15 (t, 3H), 1.02 (m, 2H), 0.75 (m, 2H). <BR> <BR> <BR> <BR> <P>N-butyl-5-cyclopropyl-3- (2-hydroxy-4-methoxyphenyl)-lH-pyrazole-l-carboxamide, [M+H] + = 330. lH-NMR (DMSO d6) diagnostic signals (ppm): 9.82 (s, 1H), 8. 57 (t, 1H), 7.67 (d, 1H), 6.56 (s, 1H), 6.47 (m, 2H), 3.74 (s, 3H), 3.25 (m, 2H), 2.75 (m, 1H), 1.55 (m, 2H), 1.33 (m, 2H), 1.02 (m, 2H), 0.90 (t, 3H), 0.75 (m, 2H).

N-butyl-5-cyclopropyl-3-(2-hydroxy-5-methylphenyl)-1H-pyr azole-1-carboxamide, [M+H] += 314. IH-NMR (DMSO d6) diagnostic signals (ppm): 9.55 (s, 1H), 8. 58 (t, 1H), 7.58 (d, 1H), 7.0 (d, 1H), 6. 81 (d, 1H), 6.63 (s, 1H), 3.25 (m, 2H), 2.75 (m, 1H), 2.23 (s, 3H), 1.56 (m, 2H), 1.34 (m, 2H), 1.01 (m, 2H), 0.91 (t, 3H), 0.75 (m, 2H).

N-(3-{1-[(butylamino)carbonyl]-5-cyclopropyl-1H-pyrazol-3 -yl}-4- hydroxyphenyl) isonicotinamide, [M+H] + = 420. IH-NMR (DMSO d6) diagnostic signals (ppm): 9. 68 (s, 1H), 8. 78 (d, 1H), 8.52 (t, 1H), 8. 02 (s, 1H), 7. 86 (d, 1H), 7.55 (dd, 1H), 6.94 (d, 1H), 6.51 (s, 1H), 3.25 (m, 2H), 2.75 (m, 1H), 1.56 (m, 2H), 1.34 (m, 2H), 1.01 (m, 2H), 0.87 (t, 3H), 0.75 (m, 2H).

N-(4-{1-[(butylamino)carbonyl]-5-cyclopropyl-1H-pyrazol-3 -yl}-3- hydroxyphenyl) isonicotinamide, [M+H] + = 420. IH-NMR (DMSO d6) diagnostic signals (ppm): 10.48 (s, 1H), 9.87 (s, 1H), 8.78 (d, 1H), 8. 55 (t, 1H), 7.86 (d, 2H), 7.78 (d, 1H), 7.55 (s, 1H), 7.27 (dd, 1H), 6.61 (s, 1H), 3.23 (m, 2H), 2.76 (m, 1H), 1.56 (m, 2H), 1.34 (m, 2H), 1.01 (m, 2H), 0.91 (t, 3H), 0.75 (m, 2H). <BR> <BR> <BR> <BR> <P>3- {4- [ (1, 3-Benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-N-butyl-5-cyclobutyl-<BR> <BR> <BR> <BR> <BR> <BR> <BR> 1H-pyrazole-l-carboxamide, [M+H] + = 477. 1H-NMR (DMSO d6) diagnostic signals (ppm): 10.0 (s, 1H), 8.52 (t, 1H), 7.61 (d, 1H), 7.59 9d, 1H), 7.56 (d, 1H), 7.45 (d, 1H), 7.27 (d, 1H), 7.05 (d, 1H) 6.65 (s, 1H), 6.11 (s, 2H), 3.58 (m, 1H), 3.23 (m, 2H), 2.31 (m, 2H), 2.19 (m, 2H), 1.97 (m, 2H), 1.56 (m, 2H), 1.34 (m, 2H), 0.91 (t, 3H). <BR> <BR> <BR> <BR> <P>3- {4- [ (1, 3-Benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-N-butyl-5-<BR> <BR> <BR> <BR> <BR> <BR> cyclopentyl-lH-pyrazole-l-carboxamide, [M+H] + = 491. 1H-NMR (DMSO d6) diagnostic signals (ppm): 10.05 (s, 1H), 8.52 (t, 1H), 7.60 (d, 1H), 7. 58 (d, 1H), 7.48 (d, 1H), 7.42, (s, 1H), 7.04 (d, 1H), 6.58 (s, 1H), 6.11 (s, 2H), 3.23 (m, 2H), 3.11 (m, 1H), 2.1 (m, 2H), 1.75 (m, 2H), 1.6 (m, 4H), 1.56 (m, 2H), 1.34 (m, 2H), 0.91 (t, 3H).

N-Allyl-5-cyclopropyl-3- (4-fluoro-2-hydroxyphenyl)-lH-pyrazole-l-carboxamide, [M+H] + = 302. HPLC r. t. = 6.21 5- (3, 4-Dimethoxyphenyl)-N-ethyl-3- (2-hydroxy-5-methoxyphenyl)-lH-pyrazole-l- carboxamide, [M+H] + = 398. HPLC r. t. = 4.59 N-Allyl-5-[2-(dimethylamino) ethyl]-3-(2-hydroxy-5-methylphenyl)-lH-pyrazole-1- carboxamide, [M+H] + =329 HPLC r. t. = 3. 75. <BR> <BR> <BR> <BR> <P>5-[2-(Dimethylamino) ethyl]-3-(2-hydroxy-5-methoxyphenyl)-N-(2-phenylethyl)-lH-&l t;BR> <BR> <BR> <BR> <BR> pyrazole-1-carboxamide, [M+H] + = 409. HPLC r. t. = 4. 39.

Ethyl-N- [5-(3,4-dimethoxyphenyl)-3-(2-hydroxy-5-methoxyphenyl)-1H-py razol-1- yl] carbonyl} glycinate, [M+H] + = 456. HPLC r. t. = 4.69 <BR> <BR> <BR> <BR> 5-Cyclopropyl-N-ethyl-3-(4-fluoro-2-hydroxyphenyl)-lH-pyrazo le-1-carboxamide, [M+H] + = 290. HPLC r. t. = 6.01 Ethyl-N- [3- (5-chloro-2-hydroxyphenyl)-5-cyclopropyl-lH-pyrazol-l- yl] carbonyl} glycinate, [M+H] + = 364. HPLC r. t. = 6.21 5-Cyclopropyl-3-(2-hydroxy-5-methoxyphenyl)-N-(2-phenylethyl )-lH-pyrazole-l- carboxamide, [M+H] + = 377. HPLC r. t. = 6.55.

5-Cyclopropyl-N-ethyl-3- (2-hydroxyphenyl)-lH-pyrazole-l-carboxamide, [M+H] + = 271. HPLC r. t. = 5. 76.

N-allyl-5- (3, 4-dimethoxyphenyl)-3- (2-hydroxy-5-methoxyphenyl)-lH-pyrazole-1- carboxamide, [M+H] + = 410. HPLC r. t. = 4.71.

N-benzyl-5- (3, 4-dimethoxyphenyl)-3- (2-hydroxy-5-methylphenyl)-lH-pyrazole-l- carboxamide, [M+H] + = 444. HPLC r. t. = 5. 41. <BR> <BR> <BR> <BR> <P>N-allyl-5-cyclopropyl-3-(2-hydroxy-5-methoxyphenyl) -lH-pyrazole-l-carboxamide, [M+H] + = 314. HPLC r. t. = 5.80. <BR> <BR> <BR> <BR> <P>N-benzyl-5- [2-(dimethylamino) ethyl]-3-(2-hydroxy-5-methoxyphenyl)-lH-pyrazole-l- carboxamide, [M+H] + = 394. HPLC r. t. = 4.20.

5-Cyclopropyl-3-(2-hydroxy-5-methylphenyl)-N-(2-phenyleth yl)-1H-pyrazole-1- carboxamide, [M+H] + = 362. HPLC r. t. = 6.90.

5-[2-(Dimethylamino) ethyl]-N-ethyl-3-(2-hydroxyphenyl)-lH-pyrazole-1- carboxamide, [M+H] + = 302. HPLC r. t. = 3.24.

Ethyl N-[(5-cyclobutyl-3-{2-hydroxy-4-[(3-methoxybenzoyl) amino] phenyl}-lH- pyrazol-1-yl) carbonyl] glycinate, [M+H] + = 493. HPLC r. t. = 7.27.

Ethyl N- [ (5-cyclopropyl-3- {2-hydroxy-4- [ (3-methoxybenzoyl) amino] phenyl}-lH- pyrazol-1-yl) carbonyl] glycinate, [M+H] + = 479. HPLC r. t. = 6.87.

Operting in an analogous way, the following compounds are also obtained: 3- {4-[(2-chlorobenzoyl) atnino]-2-hydroxyphenyl}-5-cyclopropyl-N-isopropyl-lH- 1pyrazole-1-carboxamide 3- {4-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N-ethyl-lH- 2 yrazole-1-carboxamide N-allyl-3- {4- [ (2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-lH- 3 pyrazole-1-carboxamide 3- {4- [ (2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N-propyl-1H- 4 pyrazole-1-carboxamide N-benzyl-3- {4- [ (2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-1H- 5 pyrazole-l-carboxamide 3- {4-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N-(2- 6 phenylethyl)-1 H-pyrazole-1-carboxamide 3- 4- [ (2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (2- 7 methylbenzyl)-lH-pyrazole-l-carboxamide 3-14- [ (2-chlorobenzoyl) amino]-2-hydroxyphenyll-5-cyclopropyl-N- (3- 8 methylbenzyl)-1 H-pyrazole-1-carboxamide 3- 4- [ (2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (4- 9 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {4-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-N-(2-chlorobenzyl)-5- 10 cyclopropyl-lH-pyrazole-l-carboxamide 3- {4- [ (2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (4- 11 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {4-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N-(3, 4- 12 dichlorobenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (4- 13 methoxybenzyl)-lH-pyrazole-1-carboxamide N-(sec-butyl)-3- {4-[(2-chlorobenzoyl) arnino]-2-hydroxyphenyl}-5-cyclopropyl- 14 1H-pyrazole-l-carboxamide 3- {4-[(2-chlorobenzoyl) amino3-2-hydroxyphenyl}-5-cyclopropyl-N-(2- 15 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (3- 16 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {4-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-N, 5-dicyclopropyl-lH- 17 pyrazole-1-carboxamide 3- {4-[(2-chlorobenzoyl) amino3-2-hydroxyphenyl}-5-cyclobutyl-N-isopropyl-lH- 18 pyrazole-1-carboxamide 3- {4-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-ethyl-lH- 19 pyrazole-1-carboxamide N-allyl-3- {4- [ (2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-lH- 20 pyrazole-l-carboxamide 3- {4-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-propyl-lH- 21 pyrazole-1-carboxamide N-benzyl-3- {4-[(2-chlorobenzoyl) amino3-2-hydroxyphenyl}-5-cyclobutyl-lH- 22 pyrazole-1-carboxamide 23 3- {4-[(2-chlorobenzoyl) arnino]-2-hydroxyphenyl}-5-cyclobutyl-N-(2- phenylethyl)-1 H-pyrazole-1-carboxamide 3- {4-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-(2- 24 methylbenzyl)-1 H-pyrazole-1-carboxamide 3- {4- [ (2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (3- 25 methylbenzyl)-lH-pyrazole-l-carboxamide 3- 4- [ (2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (4- 26 methylbenzyl)-1 H-pyrazole-1-carboxamide 3- 4- [ (2-chlorobenzoyl) amino]-2-hydroxyphenyl}-N- (2-chlorobenzyl)-5- 27 cyclobutyl-1 H-pyrazole-1-carboxamide 3- {4- [ (2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (4- 28 fluorobenzyl)-IH-pyrazole-1-carboxamide 3- {4-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-(3, 4- 29 dichlorobenzyl)-lH-pyrazole-l-carboxamide 3- {4-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-(4- 30 methoxybenzyl)-lH-pyrazole-1-carboxamide N-(sec-butyl)-3- {4-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-lH- 31 pyrazole-1-carboxamide 3- {4-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-(2- 32 fluorobenzyl)-1 H-pyrazole-1-carboxamide 3- 4- [ (2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (3- 33 fluorobenzyl)-lH-pyrazole-1-carboxamide 3-g4-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-cyclopropyl- 34 1H-yrazole-1-carboxamide 3- {4-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-isopropyl-lH- 35 pyrazole-l-carboxamide 3-{4-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-ethyl-lH- 36 pyrazole-1-carboxamide N-allyl-3- {4-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-lH- 37 pyrazole-1-carboxamide 3- {4-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-propyl-lH- 38 pyrazole-1-carboxamide N-benzyl-3- {4- [(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-1 H- 39 pyrazole-1-carboxamide 3- {4-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-(2- 40 phenylethyl)-IH-pyrazole-l-carboxamide 3- {4-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-(2- 41 methylbenzyl)-1 H-pyrazole-1-carboxamide 3- {4-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-(3- 42 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {4-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cycIopentyl-N-(4- 43 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {4-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-N-(2-chlorobenzyl)-5- 44 cyclopentyl-1 H-pyrazole-1-carboxamide 3- {4-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-(4- 45 fluorobenzyl)-1 H-pyrazole-I-carboxamide 5-cyclopropyl-3- {4-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-isopropyl- 46 1 H-pyrazole-1-carboxamide 3- {4-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-(4- 47 methoxybenzyl)-1 H-pyrazole-1-carboxamide N-(sec-butyl)-3- {4-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl- 48 1H-pyrazole-I-carboxamide 3- {4-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-(2- 49 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (3- 50 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- 4- [ (2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-cyclopropyl- 51 1 H-pyrazole-1-carboxamide 5-cyclopropyl-3- {4- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-isopropyl- 52 IH-pyrazole-l-carboxamide 5-cyclopropyl-3- {4-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-ethyl-lH- 53 pyrazole-1-carboxamide N-allyl-5-cyclopropyl-3- {4- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-1H- 54 pyrazole-1-carboxamide 5-cyclopropyl-3- {4-[82, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-propyl- 55 IH-pyrazole-l-carboxamide N-benzyl-5-cyclopropyl-3- {4- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}- 56 1H-pyrazole-l-carboxamide 5-cyclopropyl-3- {4-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (2- 57 phenylethyl)-1 H-pyrazole-1-carboxamide 5-cyclopropyl-3-f 4- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (2- 58 methylbenzyl)-1 H-pyrazole-1-carboxamide 5-cyclopropyl-3- {4-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (3, 4- 59 dichlorobenzyl)-1 H-pyrazole-1-carboxamide 5-cyclopropyl-3- {4-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl3-N-(4- 60 methylbenzyl)-1H-pyrazole-1-carboxamide N-(2-chlorobenzyl)-5-cyclopropyl-3- {4-[(2, 6-dichlorobenzoyl) amino]-2- 61 hydroxyphenyl}-lH-pyrazole-1-carboxamide 5-cyclopropyl-3- {4-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-(4- 62 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {4- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (3, 4- 63 dichlorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {4-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (4- 64 methoxybenzyl)-lH-pyrazole-l-carboxamide N-(sec-butyl)-5-cyclopropyl-3- {4-[(2, 6-dichlorobenzoyl) amino]-2- 65 hydroxyphenyl}-1 H-pyrazole-1-carboxamide 5-cyclopropyl-3- {4-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-(2- 66 fluorobenzyl)-1 H-pyrazole-1-carboxamide -cyclopropyl-3- {4- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (3- 67 fluorobenzyl)-1H-pyrazole-1-carboxamide N, 5-dicyclopropyl-3- {4-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-lH- 68 pyrazole-1-carboxamide 5-cyclobutyl-3- {4-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-isopropyl- 69 1H-pyrazole-l-carboxamide 5-cyclobutyl-3- {4-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-ethyl-1H- 70 pyrazole-1-carboxamide N-allyl-5-cyclobutyl-3- {4- [ (2, 6-dichlorobenzoyl) arnino]-2-hydroxyphenyl}-1H- 71 yrazole-1-carboxamide 5-cyclobutyl-3- {4-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-propyl-lH- 72 pyrazole-1-carboxamide N-benzyl-5-cyclobutyl-3-f 4- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-1H- 73 pyrazole-1-carboxamide 5-cyclobutyl-3- {4-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (2- 74 phenylethyl)-1 H-pyrazole-1-carboxamide 5-cyclobutyl-3- {4-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-(2- 75 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {4- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyI}-N- (3- 76 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {4-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (4- 77 methylbenzyl)-lH-pyrazole-1-carboxamide N-(2-chlorobenzyl)-5-cyclobutyl-3- {4-[(2, 6-dichlorobenzoyl) amino]-2- 78 hydroxyphenyl-lH-pyrazole-1-carboxamide 5-cydobutyl-3- {4- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (4-. 79 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {4-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-(3, 4- 80 dichlorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3-f 4- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (4- 81 methoxybenzyl)-lH-pyrazole-l-carboxamide N- (sec-butyl)-5-cyclobutyl-3- {4- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}- 82 lH-syrazole-l-carboxamide 5-cyclobutyl-3- {4-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (2- 83 fluorobenzyl)-lH-pyrazole-1-carboxamide 5-cyclobutyl-3- {4-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-(3- 84 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-N-cyclopropyl-3- {4- [ (2, 6-dichlorobenzoyl) amino]-2- 85 hydroxyphenyl}-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {4-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-isopropyl- 86 1H-pyrazole-1-carboxamide 5-cyclopentyl-3-f 4- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-ethyl-lH- 87 pyrazole-1-carboxamide N-allyl-5-cyclopentyl-3- {4-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-1H- 88 pyrazole-1-carboxamide 5-cyclopentyl-3- {4- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-propyl- 89 1 H-pyrazole-1-carboxamide N-benzyl-5-cyclopentyl-3- {4- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}- 90 1H-yrazole-1-carboxamide 5-cyclopentyl-3-14- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (2- 91 phenylethyl)-IH-pyrazole-l-carboxamide 5-cyclopentyl-3- {4-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (2- 92 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {4-[(2, 6-dichlorobenzoyl) arnino]-2-hydroxyphenyl}-N-(3- 93 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {4-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-(4- 94 methylbenzyl)-lH-pyrazole-l-carboxamide N-(2-chlorobenzyl)-5-cyclopentyl-3- {4-[(2, 6-dichlorobenzoyl) amino]-2- 95 hydroxyphenyl-lH-pyrazole-1-carboxamide 5-cyclopentyl-3- {4- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (4- 96 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {4-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (3, 4- 97 dichlorobenzyl)-1 H-pyrazole-1-carboxamide 5-cyclopentyl-3- {4-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (4- 98 methoxybenzyl)-lH-pyrazole-l-carboxamide N- (sec-butyl)-S-cyclopentyl-3- f 4- [ (2, 6-dichlorobenzoyl) amino]-2- 99 hydroxyphenyl-lH-pyrazole-1-carboxamide 5-cyclopentyl-3- {4- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (2- 100 fluorobenzyl)-1 H-pyrazole-1-carboxamide 5-cyclopentyl-3- {4-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-(3- 101 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-N-cyclopropyl-3- {4-[(2, 6-dichlorobenzoyl) amino]-2- 102 hydroxyphenyl}-lH-pyrazole-l-carboxamide . 5-cyclopropyl-3- {2-hydroxy-4-[(2-methoxybenzoyl) amino] phenyl}-N-isopropyl- 103 1 H-pyrazole-1-carboxamide 5-cyclopropyl-N-ethyl-3- {2-hydroxy-4-[(2-methoxybenzoyl) arnino] phenyl}-lH- 104 pyrazole-1-carboxamide N-allyl-5-cyclopropyl-3- {2-hydroxy-4- [ (2-methoxybenzoyl) amino] phenyl}-lH- 105 pyrazole-I-carboxamide 5-cyclopropyl-3- {2-hydroxy-4-[(2-methoxybenzoyl) amino] phenyl}-N-propyl-lH- 106 pyrazole-1-carboxamide N-benzyl-5-cyclopropyl-3- {2-hydroxy-4-[(2-methoxybenzoyl) amino] phenyl}-lH- 107 pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-4-[(2-methoxybenzoyl) amino] phenyl}-N- (2- 108 phenylethyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {2-hydroxy-4-[(2-methoxybenzoyl) amino] phenyl}-N-(2- 109 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {2-hydroxy-4-[(2-methoxybenzoyl) aInino] phenyl}-N-(3- 110 methylbenzyl)-lH-pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-4- [ (2-methoxybenzoyl) amino] phenyl}-N- (4- 111 methylbenzyl)-lH-pyrazole-l-carboxamide N-(2-chlorobenzyl)-5-cyclopropyl-3- {2-hydroxy-4-[(2- 112 methoxybenzoyl) amino] phenyl-lH-pyrazole-l-carboxamide 5-cyclopropyl-N- (4-fluorobenzyl)-3-12-hydroxy-4- [ (2- 113 methoxybenzoyl) amino phenyl}-l H-pyrazole-1-carboxamide S-cyclopropyl-N- (3, 4-dichlorobenzyl)-3- f 2-hydroxy-4- [ (2- 114 methoxybenzoyl) amino]phenyl-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {2-hydroxy-4- [ (2-methoxybenzoyl) amino] phenyl}-N- (4- 115 methoxybenzyl)-lH-pyrazole-l-carboxamide N-(sec-butyl)-5-cyclopropyl-3- {2-hydroxy-4-[(2-methoxybenzoyl) amino] phenyl} 116 IH-pyrazole-l-carboxamide 5-cyclopropyl-N- (2-fluorobenzyl)-3- {2-hydroxy-4- [ (2- 117 methoxybenzoyl) amino henyl}-lH-pyrazole-l-carboxamide 5-cyclopropyl-N-(3-fluorobenzyl)-3- {2-hydroxy-4-[(2- 118 methoxybenzoyl) amino phenyl-lH-pyrazole-l-carboxamide N, 5-dicyclopropyl-3- {2-hydroxy-4-[(2-methoxybenzoyl) amino] phenyl}-1H- 119 pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-4- [ (2-methoxybenzoyl) amino] phenyl}-N-isopropyl- 120 IH-pyrazole-l-carboxamide 5-cyclobutyl-N-ethyl-3- {2-hydroxy-4-[(2-methoxybenzoyl) amino] phenyl}-1H- 121 yrazole-1-carboxamide N-allyl-5-cyclobutyl-3- {2-hydroxy-4-[(2-methoxybenzoyl) amino] phenyl}-1H- 122 pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-4-[(2-methoxybenzoyl) amino] phenyl}-N-propyl-1H- 123 pyrazole-1-carboxamide N-benzyl-5-cyclobutyl-3- {2-hydroxy-4- [ (2-methoxybenzoyl) amino] phenyl}-1 H- 124 pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-4-[(2-methoxybenzoyl) amino] phenyl}-N-(2- 125 phenylethyl)-lH-pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-4-[(2-methoxybenzoyl) amino] phenyl}-N- (2- 126 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- f 2-hydroxy-4- [ (2-methoxybenzoyl) amino] phenyl}-N- (3- 127 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {2-hydroxy-4-[(2-methoxybenzoyl) ainino] phenyl}-N-(4- 128 methylbenzyl)-1H-yrazole-1-carboxamide N-(2-chlorobenzyl)-5-cyclobutyl-3- {2-hydroxy-4-[(2- 129 methoxybenzoyl) amino] phenyl}-1 H-pyrazole-1-carboxamide 5-cyclobutyl-N- (4-fluorobenzyl)-3- f 2-hydroxy-4- [ (2- 130 methoxybenzoyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclobutyl-N- (3, 4-dichlorobenzyl)-3- {2-hydroxy-4- [ (2- 131 methoxybenzoyl) amino] phenyl}-1 H-pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-4-[(2-methoxybenzoyl) amino] phenyl}-N-(4- 132 methoxybenzyl)-lH-pyrazole-l-carboxamide N-(sec-butyl)-5-cyclobutyl-3- {2-hydroxy-4-[(2-methoxybenzoyl) amino] phenyl}- 133 IH-pyrazole-l-carboxamide 5-cyclobutyl-N-(2-fluorobenzyl)-3- {2-hydroxy-4-[(2- 134 methoxybenzoyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclobutyl-N- (3-fluorobenzyl)-3- {2-hydroxy-4- [ (2- 135 methoxybenzoyl) amino] phenyl-lH-pyrazole-1-carboxamide 5-cyclobutyl-N-cyclopropyl-3- {2-hydroxy-4- [(2-methoxybenzoyl) amino] phenyl}- 136 lH-Dyrazole-l-carboxamide A 5-cyclopentyl-3- {2-hydroxy-4-[(2-methoxybenzoyl) amino] phenyl}-N-isopropyl- 137 1H-yrazole-1-carboxamide 5-cyclopentyl-N-ethyl-3- {2-hydroxy-4-[(2-methoxybenzoyl) amino] phenyl}-1H- 138 pyrazole-1-carboxamide N-allyl-5-cyclopentyl-3- {2-hydroxy-4- [(2-methoxybenzoyl) amino] phenyl}-1 H- 139 pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-4-[(2-methoxybenzoyl) arnino] phenyl}-N-propyl-lE- 140 pyrazole-1-carboxamide N-benzyl-5-cyclopentyl-3-2-hydroxy 4- [ (2-methoxybenzoyl) amino] phenyl-1H- 141 pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-4-[(2-methoxybenzoyl) amino] phenyl}-N-(2- 142 phenylethyl)-lH-pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-4-[(2-methoxybenzoyl) aminojphenyl}-N-(2- 143 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {2-hydroxy-4-[(2-methoxybenzoyl) aminoaphenyl}-N-(3- 144 methylbenzyl)-1H-pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-4-[(2-methoxybenzoyl) amino] phenyl}-N-(4- 145 methylbenzyl)-1 H-pyrazole-1-carboxamide a N-(2-chlorobenzyl)-5-cyclopentyl-3- {2-hydroxy-4-[(2- 146 methoxybenzoyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclopentyl-N-(4-fluorobenzyl)-3- {2-hydroxy-4-[(2- 147 methoxybenzoyl) amino] phenyl}-1 H-yrazole-1-carboxamide A 5-cyclopentyl-N- (3, 4-dichlorobenzyl)-3- {2-hydroxy-4- [ (2- 148 methoxybenzoyl) amino] phenyl}-IH-pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-4-[(2-methoxybenzoyl) amino] phenyl}-N-(4- 149 methoxybenzyl)-lH-pyrazole-1-carboxamide N-(sec-butyl)-5-cyclopentyl-3- {2-hydroxy-4-[(2-methoxybenzoyl) amino] phenyl}- 150 1H-yrazole-1-carboxamide 5-cyclopentyl-N-(2-fluorobenzyl)-3- {2-hydroxy-4-[(2- 151 methoxybenzoyl) amino] phenyl}-IH-pyrazole-l-carboxamide 5-cyclopentyl-N-(3-fluorobenzyl)-3- {2-hydroxy-4-[(2- 152 methoxybenzoyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclopentyl-N-cyclopropyl-3- {2-hydroxy-4-[(2- 153 methoxybenzoyl) amino] phenyl}-IH-pyrazole-l-carboxamide 5-cyclopropyl-3- {2-hydroxy-4-[(2-methylbenzoyl) amino] phenyl}-N-isopropyl- 154 IH-pyrazole-l-carboxamide 5-cyclopropyl-N-ethyl-3- {2-hydroxy-4-[(2-methylbenzoyl) amino] phenyl}-1H- 155 pyrazole-1-carboxamide N-allyl-5-cyclopropyl-3- {2-hydroxy-4-[(2-methylbenzoyl) arnino] phenyl}-1H- 156 pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-4- [(2-methylbenzoyl) amino] phenyl}-N-propyl-1H- 157 pyrazole-1-carboxamide N-benzyl-5-cyclopropyl-3- {2-hydroxy-4-[(2-methylbenzoyl) amino] phenyl}-lH- 158 pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-4-[(2-methylbenzoyl) aminoaphenyl}-N-(2- 159 phenylethyl)-IH-pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-4-[(2-methylbenzoyl) amino] phenyl}-N-(2- 160 methylbenzyl)-1 H-pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-4-[(2-methylbenzoyl) amino] phenyl}-N-(3- 161 methylbenzyl)-1 H-pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-4-[(2-methylbenzoyl) amino] phenyl}-N-(4- 162 methylbenzyl)-lH-pyrazole-l-carboxamide N-(2-chlorobenzyl)-5-cyclopropyl-3- {2-hydroxy-4-[(2- 163 methylbenzoyl) amino phenyl-lH-pyrazole-1-carboxamide 5-cyclopropyl-N- (4-fluorobenzyl)-3- {2-hydroxy-4- [ (2- 164 methylbenzoyl) amino] phenyl-IH-pyrazole-l-carboxamide 5-cyclopropyl-N-(3, 4-dichlorobenzyl)-3- {2-hydroxy-4-[(2- 165 methylbenzoyl) amino] phenyl-lH-pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-4-[(2-methylbenzoyl) amino] phenyl}-N-(4 166 methoxybenzyl)-lH-pyrazole-l-carboxamide N-(sec-butyl)-5-cyclopropyl-3- {2-hydroxy-4-[(2-methylbenzoyl) amino] phenyl}- 167 1H-pyrazole-1-carboxamide S-cyclopropyl-N- (2-fluorobenzyl)-3- {2-hydroxy-4- [ (2- 168 methylbenzoyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclopropyl-N- (3-fluorobenzyl)-3- f 2-hydroxy-4- [ (2- 169 methylbenzoyl) amino] phenyl-IH-pyrazole-l-carboxamide N, 5-dicyclopropyl-3- {2-hydroxy-4-[(2-methylbenzoyl) amino] phenyl}-1H- 170 pyrazole-1-carboxamide e 5-cyclobutyl-3- {2-hydroxy-4-[(2-methylbenzoyl) amino] phcnyl}-N-isopropyl-lH- 171 pyrazole-1-carboxamide 5-cyclobutyl-N-ethyl-3- {2-hydroxy-4- [(2-methylb enzoyl) amino] phenyl}-1 H- 172 pyrazole-1-carboxamide N-allyl-5-cyclobutyl-3- {2-hydroxy-4-[(2-methylbenzoyl) amino] phenyl}-lH- 173 pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-4-[(2-methylbenzoyl) amino] phenyl}-N-propyl-1 H- 174 pyrazole-1-carboxamide N-benzyl-5-icyclobutyl-3- {2-hydroxy-4-[(2-methylbenzoyl) amino3phenyl}-1H- 175 pyrazole-l-carboxamide 5-cyclobutyl-3- {2-hydroxy-4-[(2-methylbenzoyl) amino] phenyl}-N-(2- 176 phenylethyl)-lH-pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-4-[(2-methylbenzoyl) amino] phenyl}-N- (2- 177 methylbenzyl)-1 H-pyrazole-1-carboxamide o 5-cyclobutyl-3- {2-hydroxy-4-[(2-melylbenzoyl) amino] phenyl}-N-(3- 178 methylbenzyl)-1H-pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-4-[(2-methylbenzoyl) amino] phenyl}-N- (4- 179 methylbenzyl)-lH-pyrazole-l-carboxamide N-(2-chlorobenzyl)-5-cyclobutyl-3- {2-hydroxy-4-[(2- 180 methylbenzoyl) amino phenyl}-lH-pyrazole-l-carboxamide 5-cyclobutyl-N- (4-fluorobenzyl)-3- {2-hydroxy-4- [ (2- 181 methylbenzoyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclobutyl-N- (3, 4-dichlorobenzyl)-3- f 2-hydroxy-4- [ (2- 182 methylbenzoyl) amino] phenyl-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {2-hydroxy-4-[(2-methylbenzoyl) amino] phenyl}-N-(4- 183 methoxybenzyl)-1 H-pyrazole-1-carboxamide N- (sec-butyl)-5-cyclobutyl-3- {2-hydroxy-4- [ (2-methylbenzoyl) amino] phenyl}- 184 lH-pyrazole-1-carboxamide 5-cyclobutyl-N-(2-fluorobenzyl)-3- {2-hydroxy-4-[(2- 185 methylbenzoyl) amino phenyl}-lH-pyrazole-l-carboxamide 5-cyclobutyl-N-(3-fluorobenzyl)-3- {2-hydroxy-4-[(2- 186 methylbenzoyl) amino phenyl}-lH-pyrazole-l-carboxamide 5-cyclobutyl-N-cyclopropyl-3- {2-hydroxy-4-[(2-methylbenzoyl) alnino] phenyl}- 187 1H-yrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-4-[(2-methylbenzoylamino] phenyl3-N-isopr 188 1H-pyrazole-l-carboxamide 5-cyclopentyl-N-ethyl-3- {2-hydroxy-4-[(2-methylbenzoyl) amino] phenyl}-1H- 18 pyrazole-1-carboxamide N-allyl-5-cyclopentyl-3-{2-hydroxy-4 [(2 methylbenzoyl) amino] phenyl}-1H- 190 pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-4-[(2-methylbenzoyl) amino] phenyl}-N-propyl-lH- 191 pyrazole-1-carboxamide N-benzyl-5-cyclopentyl-3- {2-hydroxy-4-[(2-methylbenzoyl) amino] phenyl}-1H- 192 pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-4-[(2-methylbenzoyl) amino] phenyl}-N-(2- 193 phenylethyl)-1 H-pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-4- [ (2-methylbenzoyl) amino] phenyl}-N- (2- 194 methylbenzyl)-lH-yrazole-l-carboxamide 5-cyclopentyl-3- {2-hydroxy-4-[(2-methylbenzoyl) amino] phenyl}-N-(3- 195 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {2-hydroxy-4- [ (2-methylbenzoyl) amino] phenyl}-N- (4- 196 methylbenzyl)-1 H-pyrazole-1-carboxamide N- (2-chlorobenzyl)-5-cyclopentyl-3- {2-hydroxy-4- [ (2- 197 methylbenzoyl) amino phenyl}-lH-pyrazole-l-carboxamide 5-cyclopentyl-N- (4-fluorobenzyl)-3- {2-hydroxy-4- [ (2- 198 methylbenzoyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclopentyl-N-(3, 4-dichlorobenzyl)-3- {2-hydroxy-4-[(2- 199 methylbenzoyl) amino] phenyl-lH-pyrazole-l-carboxamide e . 5-cyclopentyl-3- {2-hydroxy-4-[(2-methylbenzoyl) amino] phenyl}-N-(4- 200 methoxybenzyl)-lH-pyrazole-l-carboxamide N-(sec-butyl)-5-cyclopentyl-3- {2-hydroxy-4-[(2-methylbenzoyl) amino] phenyl}- 201 1H-yrazole-1-carboxamide 5-cyclopentyl-N-(2-fluorobenzyl)-3- {2-hydroxy-4-[(2- 202 methylbenzoyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclopentyl-N- (3-fluorobenzyl)-3- {2-hydroxy-4- [ (2- 203 methylbenzoyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclopentyl-N-cyclopropyl-3- {2-hydroxy-4-[(2-methylbenzoyl) amino] phenyl}- 204 lH-pyrazole-l-carboxamide 5-cyclopropyl-3- (2-hydroxy-4- { [3- (triftuoromethyl) benzoyl] ammo} phenyl)-N- 205 isopropyl-lH-pyrazole-l-carboxamide 5-cyclopropyl-N-ethyl-3- (2-hydroxy-4- { [3- 206 (trifluoromethyl) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide N-allyl-5-cyclopropyl-3- (2-hydroxy-4- { [3- 207 (trifluoromethyl) benzoyl] amino} phenyl)-1H-pyrazole-1-carboxamide 5-cyclopropyl-3-(2-hydroxy-4- {[3-(trifluoromethyl) benzoyl] amino} phenyl)-N- 208 propyl-IH-pyrazole-l-carboxamide N-benzyl-5-cyclopropyl-3-(2-hydroxy-4- { [3- 209 (trifluoromethyl) benzoyl] amino henyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3-(2-hydroxy-4- {[3-(trifluoromethyl) benzoyl] amino} phenyl)-N- (2- 210 phenylethyl)-1 H-pyrazole-1-carboxamide 5-cyclopropyl-3-(2-hydroxy-4- {[3-(trifluoromethyl) benzoyl] ammo} phenyl)-N- (2- 211 methylbenzyl)-IH-pyrazole-l-carboxamide 5-cyclopropyl-3-(2-hydroxy-4- {[3-(trifluoromethyl) benzoyl] amino} phenyl)-N- (3- 212 methylbenzyl)-IH-pyrazole-l-carboxamide 5-cyclopropyl-3-(2-hydroxy-4- {[3-(trifluoromethyl) benzoyl] amino} phenyl)-N- (4- 213 methylbenzyl)-lH-pyrazole-1-carboxamide N-(2-chlorobenzyl)-5-cyclopropyl-3-(2-hydroxy-4- {[3- 214 (trifluoromethyl) benzoyl amino henyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-N-(4-fluorobenzyl)-3-(2-hydroxy-4- {[3- 215 (trifluoromethyl) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-N- (3, 4-dichlorobenzyl)-3- (2-hydroxy-4- { [3- 216 (trifluoromethyl) benzoyl] amino henyl)-1 H-pyrazole-1-carboxamide 5-cyclopropyl-3-(2-hydroxy-4- {[3-(trifluoromethyl) benzoyl] amino} phenyl)-N-(4- 217 methoxybenzyl)-1 H-pyrazole-1-carboxamide N-(sec-butyl)-5-cyclopropyl-3-(2-hydroxy-4- { [3- 218 (trifluoromethyl) benzoyl] amino}phenyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-N-(2-fluorobenzyl)-3-(2-hydroxy-4- {[3- 219 (trifluoromethyl) benzoyl] amino}phenyl)-1H-pyrazole-1-carboxamide N-allyl-5-cyclobutyl-3-(2-hydroxy-4- { [3- 220 (trifluoromethyl) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide N, 5-dicyclopropyl-3-(2-hydroxy-4- {[3-(trifluoromethyl) benzoyl] aminophenyl)- 221 lH-Dyrazole-l-carboxamide A 5-cyclobutyl-3- (2-hydroxy-4- { [3- (trifluoromethyl) benzoyl] amino} phenyl)-N- 222 iso ro yl-1H-yrazole-l-carboxamide x A 5-cyclobutyl-N-ethyl-3- (2-hydroxy-4- { [3- 223 (trifluoromethyl) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide N-allyl-5-cyclobutyl-3- (2-hydroxy-4- {[3- 224 (trifluoromethyl) benzoyllamino} phenyl)-lH-yrazole-l-carboxamide 5-cyclobutyl-3-(2-hydroxy-4- {[3-(trifluoromethyl) benzoyllamino} phenyl)-N- 225 propyl-lH-pyrazole-1-carboxamide N-benzyl-5-cyclobutyl-3-(2-hydroxy-4- {[3- 226 (trifluoromethyl benzoyl] amino phenyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- (2-hydroxy-4- { [3- (trifluoromethyl) benzoyl] amino} phenyl)-N- (2- 227 ohenylethyl)-lH-syrazole-1-carboxamide 5-cyclobutyl-3-(2-hydroxy-4- {[3-(trifluoromethyl) benzoyl] amino3phenyl)-N-(2- 228 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3-(2-hydroxy-4- {[3-(trifluoromethyl) benzoyl] amino} phenyl)-N- (3- 229 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3-(2-hydroxy-4- {[3-(trifluoromethyl) benzoyl] amino} phenyl)-N- (4- 230 methylbenzyl)-lH-pyrazole-l-carboxamide N- (2-chlorobenzyl)-5-cyclobutyl-3- (2-hydroxy-4- { [3- 231 (trifluoromethyl) benzoyl] amino henyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-N- (4-fluorobenzyl)-3- (2-hydroxy-4- { [3- 232 (trifluoromethyl) benzoyllamino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-N- (3, 4-dichlorobeuzyl)-3- (2-hydroxy-4- { [3- 233 (trifluoromethyl) benzoyllarnìno} phenyl)-lH-pyrazole-l-carboxamide a 5-cyclobutyl-3-(2-hydroxy-4-{[3-(trifluoromethyl) benzoyl] amino} phenyl)-N-(4- 234 methoxybenzyl)-lH-pyrazole-1-carboxamide N- (sec-butyl)-5-cyclobutyl-3- (2-hydroxy-4- { [3- 235 (trifluoromethyl) benzoyl] amino henyl)-1H-pyrazole-1-carboxamide 5-cyclobutyl-N-(2-fluorobenzyl)-3-(2-hydroxy-4- {[3- 236 (trifluoromethyl) benzoyllamino} Phenyl)-lH-eyrazole-l-carboxamide 5-cyclobutyl-N- (3-fluorobenzyl)-3- (2-hydroxy-4-f [3- 237 (trifluoromethyl) benzoyl] aminoTphenyl)-lH-yrazole-l-carboxarnide 5-cyclobutyl-N-cyclopropyl-3- (2-hydroxy-4- { [3- 238 (trifluoromethyl) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxarilide 5-cyclopentyl-3-(2-hydroxy-4- {[3-(trifluoromethyl) benzoyl] amino} phenyl)-N- 239 isopropyl-1 H-pyrazole-1-carboxamide 5-cyclopentyl-N-ethyl-3-(2-hydroxy-4- {[3- 240 (trifluoromethyl) benzoyl] amino phenyl)-1 H-pyrazole-1-carboxamide N-allyl-5-cyclopentyl-3-(2-hydroxy-4- {[3- 241 (trifluoromethyl) benzoyl aminolPhenyl)-1 H-Pyrazole-1-carboxaltide 5-cyclopentyl-3-(2-hydroxy-4- {[3-(trifluoromethyl) benzoyl] amino} phenyl)-N- 242 propyl-lH-pyrazole-1-carboxamide A A A N-benzyl-5-cyclopentyl-3-(2-hydroxy-4- { [3- 243 (trifluoromethyl) benzoyl] amino}phenyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3-(2-hydroxy-4- {[3-(trifluoromethyl) benzoyl] amino} phenyl)-N-(2- 244 phenylethyl)-1 H-pyrazole-1-carboxamide 5-cyclopentyl-3-(2-hydroxy-4- {[3-(trifluoromethyl) benzoyl] amino} phenyl)-N-(2- 245 methylbenzyl)-I H-pyrazole-1-carboxamide 5-cyclopentyl-3-(2-hydroxy-4- {[3-(trifluoromethyl) benzoyl] amino} phenyl)-N- (3- 246 methylbenzyl)-1 H-pyrazole-1-carboxamide 5-cyclopentyl-3-(2-hydrox, y-4- {[3-(tri, fluoromethyl) benzoyl] amino} phenyl)-N-(4- 247 methylbenzyl)-lH-pyrazole-l-carboxamide A N- (2-chlorobenzyl)-5-cyclopentyl-3- (2-hydroxy-4- { [3- 248 (trifluoromethyl) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide A A 5-cyclopentyl-N- (4-fltzorobenzyl)-3- (2-hydroxy-4- f [3- 249 (trifluoromethyl) benzoyllamino} nhenyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-N- (3, 4-dichlorobenzyl)-3- (2-hydroxy-4- { [3- 250 (trifluoromethyl) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- (2-hydroxy-4- { [3- (trifluoromethyl) benzoyl] amino} phenyl)-N- (4- 251 methoxybenzyl)-lH-pyrazole-l-carboxamide A N- (sec-butyl)-5-cyclopentyl-3- (2-hydroxy-4- { [3- 252 (trifluoromethyl) benzoyll amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-N-(2-fluorobenzyl)-3-(2-hydroxy-4- {[3- 253 (trifluoromethyl) benzoyl] amino} phenyl)-1H-pyrazole-1-carboxamide 5-cyclopentyl-N-(3-fluorobenzyl)-3-(2-hydroxy-4- {[3- 254 (trifluoromethyl) benzoyl] amino henyl)-lH-pyrazole-l-carboxamide . 5-cyclopentyl-N-cyclopropyl-3-(2-hydroxy-4- {[3- 255 (trifluoromethyl) benzoyl] amino} phenyl)-1H-pyrazole-1-carboxamide 3- {4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N-isopropyl-lH- 256 pyrazole-1-carboxamide 3- 4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N-ethyl-lH- 257 pyrazole-1-carboxamide N-allyl-3- {4-[(4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-lH- 258 yrazole-1-carboxamide 3- 4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N-propyl-1H- 259 pyrazole-l-carboxamide N-benzyl-3- {4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-lH- 260 yrazole-1-carboxamide 3- 4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (2- 261 phenylethyl)-1H-pyrazole-l-carboxamide 3- {4-[(4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N-(4- 262 fluorobenzyl)-lH-pyrazole-l-carboxatnide 3- 4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (3- 263 methylbenzyl)-lH-yrazole-l-carboxamide 3- 4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (4- 264 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (4-chlorobenzoyl) ammo]-2-hydroxyphenyl}-N- (2-chlorobenzyl)-5- 265 cyclopropyl-lH-pyrazole-l-carboxamide 3- {4- [ (4-chlorobenzpyl) ammo]-2-hydroxyphenyl}-5-cyclopropyl-N- (4- 266 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (3, 4- 267 dichlorobenzyl)-1 H-pyrazole-1-carboxamide 3- 4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (4- 268 methoxybenzyl)-lH-pyrazole-l-carboxamide N- (sec-butyl)-3- {4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl- 269 1 H-pyrazole-1-carboxamide 3- {4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (2- 270 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (3- 271 fluorobenzyl)-lH-pyrazole-1-carboxamide 3- {4-[(4-chlorobenzoyl) amino]-2-hydroxyphenyl}-N, 5-dicyclopropyl-lH- 272 pyrazole-1-carboxamide 3- {4-[(4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-isopropyl-lH- 273 pyrazole-1-carboxamide 3- {4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-ethyl-1H- 274 pyrazole-1-carboxamide N-allyl-3- {4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-lH- 275 pyrazole-1-carboxamide 3- {4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-propyl-1 H- 276 pyrazole-1-carboxamide N-benzyl-3- {4-[(4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-lH- 277 pyrazole-1-carboxamide 3- {4-[(4-chlorobenzoyl) aArnino]-2-hydroxyphenyl}-5-cyclobutyl-N-(2- 278 phenylethyl)-1 H-pyrazole-1-carboxamide 3- {4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (2- 279 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (3- 280 methylbenzyl)-1H-pyrazole-1-carboxamide 3- {4- [ (4-chlorobenzoyl) aniino]-2-hydroxyphenyll-5-cyclobutyl-N- (4- 281 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (4-chlorobenzoyl) ammo]-2-hydroxyphenyl}-N- (2-chlorobenzyl)-5- 282 cyclobutyl-lH-pyrazole-l-carboxamide 3- {4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (4- 283 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (3, 4- 284 dichlorobenzyl)-lH-pyrazole-l-carboxamide 314- [ (4-chlorobenzoyl) aniinol-2-hydroxyphenyl}-5-cyclobutyl-N- (4- 285 xybenzyl)-lH-pyrazole-l-carboxamide N-(sec-butyl)-3- {4-[(4-chlorobenzoyl) arnAino]-2-hydroxyphenyl}-5-cyclobutyl-lH 286 pyrazole-1-carboxamide 3- {4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (2- 287 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (3- 288 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (4-chlorobenzoyl) ammo]-2-hydroxyphenyl}-5-cyclobutyl-N-cyclopropyl- 289 1H-pyrazole-1-carboxamide 3- {4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-isopropyl-lH- 290 pyrazole-1-carboxamide 3- {4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopcntyl-N-ethyl-lH- 291 pyrazole-1-carboxamide N-allyl-3- {4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-1H- 292 pyrazole-1-carboxamide 3- {4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-propyl-lH- 293 pyrazole-I-carboxamide N-benzyl-3- {4- [ (4-chlorobenzoyl) ammo]-2-hydroxyphenyl}-5-cyclopentyl-lH- 294 pyrazole-1-carboxaxnide 3-f4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (2- 295 phenylethyl)-l H-pyrazole-1-carboxawnide 3- {4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (2- 296 methylbenzyl)-1 H-pyrazole-I-carboxamide 3-f 4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (3- 297 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (4- 298 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {4-[(4-chlorobenzoyl) amino]-2-hydroxyphenyl}-N-(2-chlorobenzyl)-5- 299 cyclopentyl-lH-pyrazole-l-carboxamide 3- {4- [ (4-chlorobenzoyl) ammo]-2-hydroxyphenyl}-5-cyclopentyl-N- (4- 300 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- 4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (3, 4- 301 dichlorobenzyl)-1 H-pyrazole-1-carboxamide 3- {4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (4- 302 methoxybenzyl)-lH-pyrazole-l-carboxamide N- (sec-butyl)-3- {4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl- 303 1H-pyrazole-l-carboxamide 3- 4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (2- 304 fluorobenzyl)-1 H-pyrazole-1-carboxamide 3- {4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (3- 305 fluorobenzyl)-1 H-pyrazole-1-carboxamide 3-f4- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-cyclopropyl- 306 1H-pyrazole-l-carboxamide 5-cyclopropyl-3- {4-[(4-ethoxybenzoyi) amino]-2-hydroxyphenyl}-N-isopropyl- 307 1H-pyrazole-l-carboxamide 5-cyclopropyl-3- {4-[(4-ethoxybenzoyl) atnino]-2-hydroxyphenyl}-N-ethyl-lH- 308 pyrazole-l-carboxamide N-allyl-5-cyclopropyl-3- {4-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-lH- 309 yrazole-1-carboxamide 5-cyclopropyl-3- {4-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-propyl-1H- 310 pyrazole-1-carboxamide N-benzyl-5-cyclopropyl-3- {4-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-IH- 311 pyrazole-l-carboxamide 5-cyclopropyl-3- {4-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-(2- 312 phenylethyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {4-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-(2- 313 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {4- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N- (3- 314 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- 4- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N- (4- 315 methylbenzyl)-lH-pyrazole-1-carboxamide N-(2-chlorobenzyl)-5-cyclopropyl-3- {4-[(4-ethoxybenzoyl) amino]-2- 316 hydroxyphenyl}-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {4- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N- (4- 317 fluorobenzyl)-lH-pyrazole-1-carboxamide 5-cyclopropyl-N-(3, 4-dichlorobenzyl)-3- {4-[(4-ethoxybenzoyl) amino]-2- 318 hydroxyphenyl}-lH-pyrazole-1-carboxarnide 5-cyclopropyl-3- {4-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-(4- 319 methoxybenzyl)-lH-pyrazole-l-carboxamide N- (sec-butyl)-5-cyclopropyl-3- {4- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}- 320 IH-pyrazole-l-carboxamide 5-cyclopropyl-3- {4-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-(2- 321 fluorobenzyl)-lH-pyrazole-1-carboxamide 5-cyclopropyl-3- {4- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N- (3- 322 fluorobenzyl)-1H-pyrazole-1-carboxamide N, 5-dicyclopropyl-3- {4-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-1H- 323 pyrazole-1-carboxamide 5-cyclobutyl-3- {4- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-i soprop yl-1 H- 324 pyrazole-I-carboxamide 5-cyclobutyl-3-{4-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-ethyl-lH- 325 pyrazole-1-carboxamide N-allyl-5-cyclobutyl-3- {4- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-lH- 326 pyrazole-l-carboxamide 5-cyclobutyl-3-{4-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-propyl-lH- 327 yrazole-1-carboxamide E N-benzyl-5-cyclobutyl-3- {4- [ (4-ethoxybenzoyl) ammo]-2-hydroxyphenyl}-lH- 328 pyrazole-1-carboxamide 5-cyclobutyl-3- {4-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-(2- 329 phenylethyl)-lH-pyrazole-1-carboxamide 5-cyclobutyl-3- {4-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-(2- 330 methylbenzyl-IH-yrazole-1-carboxamide 5-cyclobutyl-3- {4-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-(3- 331 methylbenzyl)-lH-pyrazole-l-carboxamide A 5-cyclobutyl-3- {4-[(4-ethoxybenzoyl) amino3-2-hydroxyphenyl}-N-(4- 332 methylbenzyl)-lH-pyrazole-l-carboxamide N- (2-chlorobenzyl)-5-cyclobutyl-3- {4- [ (4-ethoxybenzoyl) amino]-2- 333 hydrox henyl}-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {4- [ (4-cthoxybenzoyl) ammo]-2-hydroxyphenyl}-N- (4- 334 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-N- (3, 4-dichlorobenzyl)-3- {4- [ (4-ethoxybenzoyl) amino]-2- 335 hydrox henyl-1H-yrazole-1-carboxamide 5-cyclobutyl-3- 4- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N- (4- 336 methoxybenzyl)-lH-pyrazole-l-carboxamide N- (sec-butyl)-5-cyclobutyl-3- {4- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}- 337 1H-pyrazole-1-carboxamide 5-cyclobutyl-3- {4- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N- (2- 338 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3-f 4- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N- (3- 339 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-N-cyclopropyl-3- {4-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}- 340 1 H-pyrazole-1-carboxamide 5-cyclopentyl-3- {4- [ (4-ethoxybenzoyl) ammo]-2-hydroxyphenyl}-N-isopropyl-lH- 341 yrazole-1-carboxamide 5-cyclopentyl-3- {4-[(4-ethoxybenzoyl) arnino]-2-hydroxyphenyl}-N-ethyl-1H- 342 yrazole-1-carboxamide N-allyl-5-cyclopentyl-3- {4- [ (4rethoxybenzoyl) amino]-2-hydroxyphenyl}-1H- 343 pyrazole-1-carboxamide 5-cyclopentyl-3- {4- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-propyl-lH- 344 pyrazole-1-carboxamide N-benzyl-5-cyclopentyl-3- {4-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-lH- 345 pyrazole-1-carboxamide 5-cyclopentyl-3- 4- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N- (2- 346 phenylethyl)-1 H-pyrazole-1-carboxamide 5-cyclopentyl-3- {4- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N- (2- 347 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {4-[(4-ethoxybenzoyl) aAino]-2-hydroxyphenyl}-N-(3- 348 methylbenzyl)-1 H-pyrazole-1-carboxamide 5-cyclopentyl-3-t4-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-(4- 349 methylbenzyl)-lH-pyrazole-l-carboxamide N-(2-chlorobenzyl)-5-cyclopentyl-3-{4-[(4-ethoxybenzoyl) arnino]-2- 350 hydroxyphenyl}-lHXpyrazole-1-carboxamide 5-cyclopentyl-3- {4-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-(4- 351 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-N-(3, 4-dichlorobenzyl)-3- {4-[(4-ethoxybenzoyl) amino]-2- 352 hydroxyphenyl}-1H-pyrazole-1-carboxamide 5-cyclopentyl-3-f4- [ (4-ethoxybenzoyl) atnino]-2-hydroxyphenyl}-N- (4- 353 methoxybenzyl)-lH-pyrazole-l-carboxamide N-(sec-butyl)-5-cyclopentyl-3- {4-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}- 354 1H-pyrazole-1-carboxamide 5-cyclopentyl-3- {4- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N- (2- 355 fluorobenzyl)-H-pyrazole-1-carboxamide 5-cyclopentyl-3- {4- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N- (3- 356 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-N-cyclopropyl-3- {4- [ (4-ethoxybenzoyl) ammo]-2-hydroxyphenyl}- 357 lH-pyrazole-1-carboxamide 3- {4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N-propyl-lH- 358 pyrazole-l-carboxamide 3- {4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N-ethyl-1H- 359 pyrazole-I-carboxamide N-allyl-3- {4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-lH- 360 pyrazole-1-carboxamide 3- {4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N-propyl-lH- 361 pyrazole-1-carboxamide N-benzyl-3- 4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-lH- 362 pyrazole-1-carboxamide 3- {4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (2- 363 phenylethyl)-lH-pyrazole-l-carboxamide 3- {4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (2- 364 methylbenzyl)-IH-pyrazole-1-carboxamide 3- {4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (3- 365 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (4-tert-butylbenzoyl) ammo]-2-hydroxyphenyl}-5-cyclopropyl-N- (4- 366 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {4-[(4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-N-(2-chlorobenzyl)-5- 367 cyclopropyl-lH-pyrazole-l-carboxamide 3- {4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (4- 368 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (4-tert-butylbenzoyl) ammo]-2-hydroxyphenyl}-5-cyclopropyl-N- (3, 4- 369 dichlorobenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (4- 370 methoxybenzyl)-lH-pyrazole-l-carboxamide N- (sec-butyl)-3- {4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5- 371 cyclopropyl-1 H-pyrazole-1-carboxamide 3- {4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (2- 372 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (3- 373 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-N, 5-dicyclopropyl-lH- 374 pyrazole-1-carboxamide 3- {4-[(4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-isopropyl- 375 1 H-pyrazole-1-carboxamide 3- {4- [ (4-tert-butylbenzoyl) ammo]-2-hydroxyphenyl}-5-cyclobutyl-N-ethyl-lH- 376 pyrazole-l-carboxamide N-allyl-3-{4-[(4-tert-butylbenzoyl) arnino]-2-hydroxyphenyl}-5-cyclobutyl-lH- 377 pyrazole-l-carboxamide 3- {4-[(4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-propyl-lH- 378 pyrazole-I-carboxamide N-benzyl-3- {4-[(4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-1 H- 379 pyrazole-1-carboxamide 3- {4- [ (4-tcrt-butylbenzoyl) ammo]-2-hydroxyphenyl}-5-cyclobutyl-N- (2- 380 phenylethyl)-lH-pyrazole-l-carboxamide 3- {4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (2- 381 methylbenzyl)-1 H-pyrazole-1-carboxamide 3- 4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (3- 382 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {4-[(4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-(4- 383 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-N- (2-chlorobenzyl)-5- 384 cyclobutyl-lH-pyrazole-l-carboxamide 3- 4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (4- 385 fluorobenzyl)-1 H-pyrazole-1-carboxamide 3- {4-[(4-tert-butylbenzoyl) aminoJ-2-hydroxyphenyl}-5-cyclobutyl-N-(3, 4- 386 dichlorobenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (4- 387 methoxybenzyl)-lH-pyrazole-l-carboxamide N- (sec-butyl)-3- {4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl- 388 1 H-pyrazole-1-carboxamide 3- {4- [ (4-tert-butylbenzoyI) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (2- 389 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (3- 390 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-cyclopropyl- 391 1 H-pyrazole-1-carboxamide 3- {4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-isopropyl- 392 1 H-pyrazole-1-carboxamide 3- {4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-ethyl-lH- 393 pyrazole-1-carboxamide N-allyl-3- {4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-lH- 394 pyrazole-1-carboxamide 3- {4-[(4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-propyl-lH- 395 pyrazole-1-carboxamide N-benzyl-3- {4-[(4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-lH- 396 pyrazole-1-carboxamide 3- {4-[(4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-(2- 397 phenylethyl)-1 H-pyrazole-1-carboxamide 3-f{4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (2- 398 methylbenzyl)-lH-pyrazole-1-carboxamide 3- {4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (3- 399 methylbenzyl)-1H-pyrazole-l-carboxamide 3- {4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (4- 400 methylbenzyl)-1 H-pyrazole-1-carboxamide 3- 4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-N- (2-chlorobenzyl)-5- 401 cyclopentyl-lH-pyrazole-l-carboxamide 3-f{4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (4- 402 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (3, 4- 403 dichlorobenzyl)-lH-pyrazole-l-carboxamide 3-14- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyll-5-cyclopentyl-N- (4- 404 methoxybenzyl)-1H-pyrazole-1-carboxamide N- (sec-butyl)-3- {4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl- 405 1H-pyrazole-1-carboxamide 3- {4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (2- 406 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- (4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (3- 407 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 408 cyclopropyl-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {2-hydroxy-4- [ (4-methylbenzoyl) amino] phenyl}-N-isopropyl- 409 1 H-pyrazole-1-carboxamide 5-cyclopropyl-N-ethyl-3- {2-hydroxy-4-[(4-methylbenzoyl) amino] phenyl}-1H- 410 pyrazole-1-carboxamide N-allyl-5-cyclopropyl-3- {2-hydroxy-4- [ (4-methylbenzoyl) amino] phenyl}-lH- 411 pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-4- [ (4-methylbenzoyl) amino] phenyl}-N-propyl-lH- 412 yrazole-1-carboxamide N-benzyl-5-cyclopropyl-3- {2-hydroxy-4-[(4-methylbenzoyl) amino] phenyl}-1H- 413 pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-4- [ (4-methylbenzoyl) amino] phenyl}-N- (2- 414 henylethyl)-1 H-pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-4-[(4-methylbenzoyl) arnino] phenyl}-N-(2-- 415 methylbenzyl)-1 H-Dyrazole-1-carboxamide A 5-cyclopropyl-3- {2-hydroxy-4- [ (4-methylbenzoyl) ammo] phenyl}-N- (3- 416 methylbenzyl)-lH-pyrazole-l-carboxamide A 5-cyclopropyl-3- {2-hydroxy-4- [ (4-methylbenzoyl) amino] phenyl}-N- (4- 417 methylbenzyl)-1H-pyrazole-1-carboxamide A N- (2-chlorobenzyl)-5-cyclopropyl-3- {2-hydroxy-4- [ (4- 418 methylbenzoyl) amino] phenyl}-1 H-pyrazole-1-carboxamide 5-cyclopropyl-N- (4-fluorobenzyl)-3- {2-hydroxy-4- [ (4- 419 methylbenzoyl) amino phenyl-lH-pyrazole-1-carboxamide 5-cyclopropyl-N- (3, 4-dichlorobenzyl)-3- {2-hydroxy-4- [ (4- 420 methylbenzoyl) amino] phenyl}-lH-pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-4- [ (4-methylbenzoyl) amino] phenyl}-N- (4- 421 methoxybenzyl)-1 H-pyrazole-1-carboxamide N- (sec-butyl)-5-cyclopropyl-3- {2-hydroxy-4- [ (4-methylbenzoyl) amino] phenyl}- 422 1H-pyrazole-l-carboxamide 5-cyclopropyl-N- (2-fluorobenzyl)-3- {2-hydroxy-4- [ (4- 423 methylbenzoyl) amino] phenyl-lH-pyrazole-l-carboxamide 5-cyclopropyl-N- (3-fluorobenzyl)-3- {2-hydroxy-4- [ (4- 424 methylbenzoyl) amino henyl}-lH-pyrazole-l-carboxamide N, 5-dicyclopropyl-3- {2-hydroxy-4- [ (4-methylbenzoyl) amino] phenyl}-1H- 425 pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-4- [ (4-methylbenzoyl) amino] phenyl}-N-isopropyl-lH- 426 pyrazole-1-carboxamide 5-cyclobutyl-N-ethyl-3- {2-hydroxy-4-[(4-methylbenzoyl) amino] phenyl}-lH- 427 pyrazole-1-carboxamide N-allyl-5-cyclobutyl-3-{2-hydroxy-4-[(4-methylbenzoyl) amino] phenyl}-lH- 428 pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-4-[(4-methylbenzoyl) amino] phenyl}-N-propyl-lH- 429 pyrazole-1-carboxamide N-benzyl-5-cyclobutyl-3- {2-hydroxy-4-[(4-methylbenzoyl) amino] phenyl}-1H- 430 pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-4- [ (4-methylbenzoyl) amino] phenyl}-N- (2- 431 phenylethyl)-1 H-pyrazole-1-carboxamide 5-eyelobutyl-3- {2-hydroxy-4-[(4-methylbenzoyl) aminogphenyl}-N-(2- 432 methylbenzyl)-1 H-pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-4- [ (4-methylbenzoyl) amino] phenyl}-N- (3- 433 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {2-hydroxy-4- [ (4-methylbenzoyl) amino] phenyl}-N- (4- 434 methylbenzyl)-lH-Dyrazole-l-carboxamide N- (2-chlorobenzyl)-5-cyclobutyl-3- {2-hydroxy-4- [ (4- 435 methylbenzoyl) aminolPhenyl}-lH-pyrazole-l-earboxamide 5-eyelobutyl-N-(4-fluorobenzyl)-3- {2-hydroxy-4-[(4- 436 methylbenzoyl) aminolshenyl}-1 H-pyrazole-1-earboxarnide 5-cyclobutyl-N- (3, 4-dichlorobenzyl)-3- {2-hydroxy-4- [ (4- 437 methylbenzoyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclobutyI-3- {2-hydroxy-4- [ (4-mcthylbenzoyl) amino] phenyl}-N- (4- 438 methoxybenzyl)-lH-pyrazole-l-carboxamide -N-(see-butyl)-5-cyclobutyl-3- {2-hydroxy-4-[(4-methylbenzoyl) amino] phenyl}- 439 1H-yrazole-1-carboxamide 5-cyclobutyl-N-(2-fluorobenzyl)-3- {2-hydroxy-4-[(4- 440 methylbenzoyl) amino H-Pvrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-4- [ (4-methylbenzoyl) amino] phenyl}-N-propyl-1 H- 441 pyrazole-I-carboxamide A 5-cyclobutyl-N-cyclopropyl-3- {2-hydroxy-4- [ (4-methylbenzoyl) ammo] phenyl}- 442 1H-azole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-4- [ (4-methylbenzoyl) amino] phenyl}-N-isopropyl- 443 1 H-pyrazole-1-carboxamide 5-cyclopentyl-N-ethyl-3- {2-hydroxy-4- [ (4-methylbenzoyl) amino] phenyl}-lH- 444 pyrazole-1-carboxamide N-allyl-5-cyclopentyl-3- {2-hydroxy-4-[(4-methylbenzoyl) amino] phenyl}-1H- 445 pyrazole-1-carboxamide 5-cyclopentyl-3-f 2-hydroxy-4- [ (4-methylbenzoyl) amino] phenyl}-N-propyl-lH- 446 pyrazole-1-carboxamide N-benzyl-5-cyclopentyl-3- {2-hydroxy-4- [ (4-methylbenzoyl) amino] phenyl}-lH- 447 pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-4- [ (4-methylbenzoyl) amino] phenyl}-N- (2- 448 phenylethyl)-1H-pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-4- [ (4-methylbenzoyl) ammo] phenyl}-N- (2- 449 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {2-hydroxy-4- [ (4-methylbenzoyl) amino] phenyl}-N- (3- 450 methylbenzyl)-1H-pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-4- [ (4-methylbenzoyl) amino] phenyl}-N- (4- 451 methylbenzyl)-lH-pyrazole-l-carboxamide N- (2-chlorobenzyl)-5-cyclopentyl-3- {2-hydroxy-4- [ (4- 452 methylbenzoyl) amino]phenyl}-lH-pyrazole-1-carboxamide 5-cyclopentyl-N- (4-fluorobenzyl)-3- {2-hydroxy-4- [ (4- 453 methylbenzoyl) amino] phenyl}-1 H-pyra zole-1-earboxamide 5-cyclopentyl-N- (3, 4-dichlorobenzyl)-3- {2-hydroxy-4- [ (4- 454 methylbenzoyl) amino] phenyl-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {2-hydroxy-4-[(4-methylbenzoyl) amino] phenyl3-N-(4- 455 methoxybenzyl)-lH-pyrazole-l-carboxamide N- (sec-butyl)-5-cyclopentyl-3- {2-hydroxy-4- [ (4-methylbenzoyl) amino] phenyl}- 456 1H-pyrazole-l-carboxamide 5-cyclopentyl-N- (2-fluorobenzyl)-3- {2-hydroxy-4- [ (4- 457 methylbenzoyl) amino phenyl-IH-pyrazole-l-carboxamide 5-cyclopentyl-N- (3-fluorobenzyl)-3- {2-hydroxy-4- [ (4- 458 methylbenzoyl) amino] phenyl-lH-pyrazole-l-carboxamide 5-cyclopentyl-N-cyclopropyl-3- {2-hydroxy-4-[(4-methylbenzoyl) amino3phenyl}- 459 1H-pyrazole-l-carboxamide 5-cyclopropyl-3- {4- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-isopropyl-lH- 460 pyrazole-l-carboxamide 5-cyclopropyl-N-ethyl-3- {4- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-lH- 461 pyrazole-1-carboxamide N-allyl-5-cyclopropyl-3- {4- [(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-1 H- 462 pyrazole-1-carboxamide 5-cyclopropyl-3- {4- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-propyl-lH- 463 pyrazole-1-carboxamide N-benzyl-5-cyclopropyl-3- {4-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-lH- 464 pyrazole-1-carboxamide 5-cyclopropyl-3- {4- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N- (2- 465 phenylethyl)-1 H-pyrazole-1-carboxamide 5-cyclopropyl-3- {4- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N- (2- 466 methylbenzyl)-lH-pyrazole-1-carboxamide 5-cyclopropyl-3- {4- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N- (3- 467 methylbenzyl)-lH-pyrazole-1-carboxamide 5-cyclobutyl-3- {4-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-isopropyl-lH- 468 pyrazole-1-carboxamide N- (2-chlorobenzyl)-5-cyclopropyl-3- {4- [ (4-ethylbenzoyl) amino]-2- 469 hydroxyphenyl}-lH pyrazole-1-carboxamide 5-cyclopropyl-3- {4-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-(4- 470 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-N- (3, 4-dichlorobenzyl)-3- {4- [ (4-ethylbenzoyl) amino]-2- 471 hydroxyphenyl}-lH-pyrazole-1-carboxarnide 5-cyclopropyl-3- {4- [ (4-ethylbenzoyl) ammo]-2-hydroxyphenyl}-N- (4- 472 methoxybenzyl)-1 H-pyrazole-1-carboxamide N- (sec-butyl)-5-cyclopropyl-3- {4- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-1H- 473 pyrazole-1-carboxamide 5-cyclopropyl-3- {4-[(4-ethylbenzoyl) ainino]-2-hydroxyphenyl}-N-(2- 474 fluorobenzyl)-1 H-pyrazole-1-carboxarnide 5-cyclopropyl-3- {4- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyll-N- (3- 475 fluorobenzyl)-1 H-pyrazole-1-carboxamide N, 5-dicyclopropyl-3- {4- [ (4-ethylbcnzoyl) ammo]-2-hydroxyphenyI}-lH-pyrazole- 476 1-carboxamide 5-cyclobutyl-3- {4-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-isopropyl-1H- 477 yrazole-1-carboxamide 5-cyclobutyl-N-ethyl-3- {4-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-1H- 478 pyrazole-l-carboxamide N-allyl-5-cyclobutyl-3- {4-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-1H- 479 pyrazole-1-carboxamide 5-cyclobutyl-3- {4- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-propyl-lH- 480 pyrazole-l-carboxamide N-benzyl-5-cyclobutyl-3- 4- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-lH- 481 pyrazole-1-carboxamide 5-cyclobutyl-3-14- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl)-N- (2-phenylethyl)- 482 IH-pyrazole-l-carboxamide 5-cyclobutyl-3- {4-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-(2- 483 methylbenzyl)-lH-pyrazole-l-carboxarnide 5-cyclobutyl-3- {4- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N- (3- 484 methylbenzyl)-1 H-pyrazole-1-carboxamide 5-cyclobutyl-3- {4- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N- (4- 485 methylbenzyl)-lH-pyrazole-l-carboxamide N- (2-chlorobenzyl)-5-cyclobutyl-3- {4- [ (4-ethylbenzoyl) amino]-2- 486 hydroxyphenyl}-lH-pyrazole-l-carboxarnide 5-cyclobutyl-3- {4-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-(4- 487 fluorobenzyl)-lH-pyrazole-l-carboxarnide 5-cyclobutyl-N- (3, 4-dichlorobenzyl)-3- {4- [ (4-ethylbenzoyl) amino]-2- 488 hydroxyphenyl}-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- 4- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N- (4- 489 methoxybenzyl)-IH-pyrazole-1-carboxamide N- (sec-butyl)-5-cyclobutyl-3- {4- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-lH- 490 yrazole-1-carboxamide 5-cyclobutyl-3- {4-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-(2- 491 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {4- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N- (3- 492 fluorobenzyl)-1 H-pyrazole-l-carboxamide 5-cyclobutyl-N-cyclopropyl-3- {4- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-1 H- 493 pyrazole-1-carboxamide 5-cyclopentyl-3- {4- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-isopropyl-1H- 494 pyrazole-l-carboxamide 5-cyclopentyl-N-ethyl-3- {4-[(4-ethylbenzoyl) åmino]-2-hydroxyphenyl}-1H- 495 pyrazole-l-carboxamide N-allyl-5-cyclopentyl-3- {4-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-lH- 496 pyrazole-1-carboxamide 5-cyclopentyl-3- {4-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-propyl-lH- 497 yrazole-1-carboxamide N-benzyl-5-cyclopentyl-3- {4-[(4-ethylbenzoyl) arnino]-2-hydroxyphenyl}-lH- 498 pyrazole-l-carboxarnide 5-cyclopentyl-3- {4- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N- (2- 499 phenylethyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {4- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N- (2- 500 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3-4- [ (4-ethylbenzoyl) amino] _2-hydroxyphenyl}-N- (3- 501 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {4- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N- (4- 502 methylbenzyl)-1H-yrazole-1-carboxamide N- (2-chlorobenzyl)-5-cyclopentyl-3- {4- [ (4-ethylbenzoyl) amino]-2- 503 hydroxyphenyl}-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {4- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N- (4- 504 fluorobenzyl)-lH-pyrazole-1-carboxamide 5-cyclopentyl-N- (3, 4-dichlorobenzyl)-3- {4- [ (4-ethylbenzoyl) arnino]-2- 505 hydroxyphenyl}-1 H-pyrazole-1-carboxamide 5-cyclopentyl-3- {4-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-(4- 506 methoxybenzyl)-1H-yrazole-1-carboxamide 06 N- (sec-butyl)-5-cyclopentyl-3- {4- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-1H- 507 yrazole-1-carboxamide 5-cyclopentyl-3- {4-[(4-ethylbenzoyl) amíno]-2-hydroxyphenyl}-N-(2- 508 fluorobenzyl)-1H-pyrazole-1-carboxamide 5-cyclopentyl-3- {4-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-(3- 509 fluorobenzyl)-1 H-pyrazole-1-carboxamide 5-cyclopentyl-N-cyclopropyl-3- {4-[(4-ethylbenzoyl) atnino]-2-hydroxyphenyl}- 510 1 H-pyrazole-1-carboxamide 5-cyclopropyl-3-[2-hydroxy-4-(isobutyrylamino) phenyl]-N-isopropyl-1 H- 511 pyrazole-l-carboxamide A 5-cyclopropyl-N-ethyl-3-r2-hydroxy-4-(isobutyrylamino) phenyl]-lH-pyrazole-l- 512 carboxamide N-allyl-5-cyclopropyl-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-lH-pyrazole-l- 513 carboxamide 5-cyclopropyl-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-N-propyl-1H-pyrazole-1- 514 carboxamide N-benzyl-5-cyclopropyl-3-[2-hydroxy-4-(isobutyrylamino) phenyl]-lH-pyrazole-l- 515 carboxamide 5-cyclopropyl-3- [2-hydroxy-4-(isobutyrylamino) phenyl]-N-(2-phenylethyl)-1 H- 516 yrazole-1-caxboxamide 5-cyclopropyl-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-N- (2-methylbenzyl)-lH- 517 pyrazole-1-carboxamide 5-cyclopropyl-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-N- (3-methylbenzyl)-1 H- 518 pyrazole-1-carboxamide 5-cyclopropyl-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-N- (4-methylbenzyl)-lH- 519 pyrazole-l-carboxamide N- (2-chlorobenzyl)-5-cyclopropyl-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-lH- 520 pyrazole-1-carboxamide 5-cyclopropyl-N- (4-fluorobenzyl)-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-lH- 521 pyrazole-1-carboxamide 5-cyclopropyl-N- (3, 4-dichlorobenzyl)-3- [2-hydroxy-4- (isobutyrylamino) phenyl]- 522 lH-pyrazole-l-carboxamide 5-cyclopropyl-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-N- (4-methoxybenzyl)- 523 1H-pyrazole-l-carboxamide N-(sec-butyl)-5-cyclopropyl-3-[2-hydroxy-4-(isobutyrylamino) phenyl]-lH- 524 pyrazole-l-carboxamide 5-cyclopropyl-N- (2-fluorobenzyl)-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-1H- 525 pyrazole-l-carboxamide 5-cyclopropyl-N- (3-fluorobenzyl)-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-1 H- 526 yrazole-1-carboxamide N, 5-dicyclopropyl-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-lH-pyrazole-l- 527 carboxamide 5-cyclobutyl-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-N-isopropyl-lH-pyrazole- 528 1-carboxamide 5-cyclobutyl-N-ethyl-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-lH-pyrazole-1- 529 carboxamide N-allyl-5-cyclobutyl-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-lH-pyrazole-l- 530 carboxamide 5-cyclobutyl-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-N-propyl-lH-pyrazole-l- 531 carboxamide N-benzyl-5-cyclobutyl-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-lH-pyrazole-l- 532 carboxamide 5-eyelobutyl-3-[2-hydroxy-4-(isobutyrylarnino) phenyl]-N-(2-phenylethyl)-1H- 533 yrazole-1-carboxamide 5-cyclobutyl-3- [2-hydroxy-4- (isobutyrylaxnino) phenyl]-N- (2-methylbenzyl)-1 H- 534 pyrazole-1-carboxamide A 5-cyelobutyl-3-[2-hydroxy-4-(isobutyrylarnino) phenyl]-N-(3-methylbenzyl)-1H- 535 pyrazole-l-carboxamide 5-cyclobutyl-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-N- (4-methylbenzyl)-lH- 536 yrazole-1-carboxamide N- (2-chlorobenzyl)-5-cyclobutyl-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-1H- 537 yrazole-1-carboxamide 5-cyclobutyl-N- (4-fluorobenzyl)-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-lH- 538 yrazole-I-carboxamide 5-cyclobutyl-N- (3, 4-dichlorobenzyl)-3- [2-hydroxy-4- (isobutyrylamino) phenyl]- 539 1H-pyrazole-l-carboxamide 5-cyclobutyl-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-N- (4-methoxybenzyl)-lH- 540 pyrazole-l-carboxamide N- (sec-butyl)-5-cyclobutyl-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-1H- 541 pyrazole-l-carboxamide 5-cyclobutyl-N- (2-fluorobenzyl)-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-lH- 542 pyrazole-1-carboxamide 5-eyclobutyl-N-(3-fluorobenzyl)-3-[2-hydroxy-4-(isobutyrylam ino) phenyl]-lH- 543 pyrazole-1-carboxamide 5-cyclobutyl-N-cyclopropyl-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-lH- 544 yrazole-1-carboxamide 5-cyclopentyl-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-N-isopropyl-lH- 545 pyrazole-l-carboxamide 5-cyclopentyl-N-ethyl-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-lH-pyrazole-l- 546 carboxamide N-allyl-5-cyclopentyl-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-lH-pyrazole-l- 547 carboxamide 5-eyelopentyl-3-[2-hydroxy-4-(isobutyrylamino) phenyl]-N-propyl-lH-pyrazole-1- 548 carboxamide N-benzyl-5-cyclopentyl-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-lH-pyrazole-1- 549 carboxamide 5-cyclopentyl-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-N- (2-phenylethyl)-lH- 550 yrazole-1-carboxamide 5-cyclopentyl-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-N- (2-methylbenzyl)-lH- 551 yrazole-1-carboxamide 5-cyclopentyl-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-N- (3-methylbenzyl)-lH- 552 pyrazole-1-carboxamide 5-cyclopentyl-3-[2-hydroxy-4-(isobutyrylamino) phenyl]-N-(4-methylbenzyl)-lH- 553 pyrazole-1-carboxarnide N- (2-chlorobenzyl)-5-cyclopentyl-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-lH- 554 pyrazole-l-carboxamide 5-cyclopentyl-N- (4-fluorobenzyl)-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-lH- 555 pyrazole-1-carboxamide 5-cyclopentyl-N- (3, 4-dichlorobenzyl)-3- [2-hydroxy-4- (isobutyrylamino) phenyl]- 556 1H-yrazole-1-carboxamide 5-cyclopentyl-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-N- (4-methoxybenzyl)- 557 1H-pyrazole-l-carboxamide N-(sec-butyl)-5-cyclopentyl-3-[2-hydroxy-4-(isobutyrylamino) phenyl]-lH- 558 pyrazole-1-carboxamide 5-cyclopentyl-N-(2-fluorobenzyl)-3-[2-hydroxy-4-(isobutyryla mino) phenyl]-lH- 559 pyrazole-1-carboxamide 5-cyclopentyl-N- (3-fluorobenzyl)-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-lH- 560 pyrazole-1-carboxamide 5-cyclopentyl-N-cyclopropyl-3- [2-hydroxy-4- (isobutyrylamino) phenyl]-1H- 561 pyrazole-1-carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclopropyl-N-isopropyl-lH- pyrazole-l- 562 carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclopropyl-N-ethyl-lH-pyra zole-l- 563 carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-N-allyl-5-cyclopropyl-lH-pyra zole-l- 564 carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclopropyl-N-propyl-lH-pyr azole-l- 565 carboxamide 3-L4-(acetylamino)-2-hydroxyphenyl]-5-cyclopropyl-N-(2-pheny lethyl)-lH- 566 pyrazole-l-carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclopropyl-N- (2-phenylethyl)-lH- 567 yrazole-1-carboxamide 1 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclopropyl-N- (2-methylbenzyl)-lH- 568 yrazole-1-carboxamide 8 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclopropyl-N- (3-methylbenzyl)-lH- 569 pyrazole-I-carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclopropyl-N- (4-methylbenzyl)-lH- 570 yrazole-1-carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-N- (2-chlorobenzyl)-5-cyclopropyl-lH- 571 yrazole-1-carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclopropyl-N- (4-fluorobenzyl)-lH- 572 pyrazole-1-carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclopropyl-N- (3, 4-dichlorobenzyl)-lH- 573 pyrazole-l-carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclopropyl-N- (4-methoxybenzyl)-1H- 574 pyrazole-1-carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-N- (sec-butyl)-5-cyclopropyl-lH-pyrazole-l- 575 carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclopropyl-N- (2-fluorobenzyl)-lH- 576 yrazole-1-carboxamide A 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclopropyl-N- (3-fluorobenzyl)-lH- 577 pyrazole-1-carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-N, 5-dicyclopropyl-lH-pyrazole-l- 578 carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclobutyl-N-isopropyl-lH-p yrazole-l- 579 carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclobutyl-N-ethyl-1 H-pyrazole-1- 580 carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-N-allyl-5-cyclobutyl-1 H-pyrazole-1- 581 carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclobutyl-N-propyl-1 H-pyrazole-1- 582 carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-N-benzyI-5-cyclobutyl-lH-pyra zole-l- 583 carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclobutyl-N- (2-phenylethyl)-lH- 584 pyrazole-1-carboxamide 3- 4- (acetylamino)-2-hydroxyphenyl]-5-cyclobutyl-N- (2-methylbenzyl)-lH- 585 pyrazole-l-carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclobutyl-N- (3-methylbenzyl)-1 H- 586 pyrazole-1-carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclobutyl-N- (4-methylbenzyl)-lH- 587 pyrazole-1-carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-N- (2-chlorobenzyl)-5-cyclobutyl-1 H- pyrazole-l-carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclobutyl-N- (4-fluorobenzyl)-lH- 589 pyrazole-l-carboxamide 3- [4- (acetylaxnino)-2-hydroxyphenyl]-5-cyclobutyl-N- (3, 4-dichlorobenzyl)-lH- 590 pyrazole-1-carboxamide v 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclobutyl-N- (4-methoxybenzyl)-lH- 591 pyrazole-1-carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-N- (sec-butyl)-5-cyclobutyl-1H-pyrazole-l- 592 carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclobutyl-N- (2-fluorobenzyl)-lH- 593 pyrazole-l-carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclobutyl-N- (3-fluorobenzyl)-lH- 594 pyrazole-l-carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclobutyl-N-cyclopropyl-lH -pyrazole-l- 595 carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclopentyl-N-isopropyl-lH- pyrazole-1- 596 carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclopentyl-N-ethyl-lH-pyra zole-l- 597 carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-N-allyl-5-cyclopentyl-lH-pyra zole-l- 598 carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclopentyl-N-propyl-lH-pyr azole-l- 599 carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-N-benzyl-5-cyclopentyl-lH-pyr azole-l- 600 carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclopentyl-N- (2-phenylethyl)-lH- 601 pyrazole-1-carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclopentyl-N- (2-methylbenzyl)-1H- 602 pyrazole-1-carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclopentyl-N- (3-methylbenzyl)-lH- 603 pyrazole-1-carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclopentyl-N- (4-methylbenzyl)-lH- 604 pyrazole-1-carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-N- (2-chlorobenzyl)-5-cyclopentyl-lH- 605 pyrazole-1-carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclopentyl-N- (4-fluorobenzyl)-lH- 606 yrazole-1-carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclopentyl-N- (3, 4-dichlorobenzyl)-lH- 607 pyrazole-1-carboxarriide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclopentyl-N- (4-methoxybenzyl)-lH- 608 pyrazole-1-carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-N- (sec-butyl)-5-cyclopentyl-1 H-pyrazole-1- 609 carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclopentyl-N- (2-fluorobenzyl)-lH- 610 pyrazole-1-carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclopentyl-N- (3-fluorobenzyl)-lH- 611 pyrazole-1-carboxamide 3- [4- (acetylamino)-2-hydroxyphenyl]-5-cyclopentyl-N-cyclopropyl-l H-pyrazole- 612 1-carboxamide 5-cyclopropyl-3- {2-hydroxy-4- [ (3-methylbutanoyl) amino] phenyl}-N-isopropyl- 613 IH-pyrazole-l-carboxamide 5-cyclopropyl-N-ethyl-3- {2-hydroxy-4- [ (3-methylbutanoyl) amino] phenyl}-1H- 614 pyrazole-I-carboxamide N-allyl-5-cyclopropyl-3- {2-hydroxy-4-[(3-methylbutanoyl) aminogphenyl}-1H- 615 yrazole-1-carboxamide A 5-cyclopropyl-3- {2-hydroxy-4-[(3-methylbutanoyl) amino] phenyl}-N-propyl-lH- 616 pyrazole-I-carboxamide s N-benzyl-5-cyclopropyl-3- {2-hydroxy-4-[(3-methylbutanoyl) amino] phenyl}-1H- 617 pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-4-[(3-methylbutanoyl) amino] phenyl}-N-(2- 618 phenylethyl)-lH-pyrazole-1-carboxamide 5-cyclopropyl-3-f 2-hydroxy-4- [ (3-methylbutanoyl) amino] phenyl}-N- (2- 619 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {2-hydroxy-4- [ (3-methylbutanoyl) amino] phenyl}-N- (3- 620 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {2-hydroxy-4- [ (3-methylbutanoyl) amino] phenyl}-N- (4- 621 methylbenzyl)-1 H-pyrazole-1-carboxamide N- (2-chlorobenzyl)-5-cyclopropyl-3- f2-hydroxy-4- [ (3- 622 methylbutanoyl) amino phenyl}-lH-pyrazole-l-carboxamide 5-cyclopropyl-N- (4-fluorobenzyl)-3- {2-hydroxy-4- [ (3- 623 methylbutanoyl) amino] phenyl}-1 H-pyrazole-1-carboxamide 5-cyclopropyl-N- (3, 4-dichlorobenzyl)-3- {2-hydroxy-4- [ (3- 624 methylbutanoyl) amino] phenyl}-1 H-pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-4-[(3-methylbutanoyl) amino] phenyl}-N-(4- 625 methoxybenzyl)-1 H-pyrazole-1-carboxamide N- (sec-butyl)-5-cyclopropyl-3- {2-hydroxy-4- [ (3-methylbutanoyl) amino] phenyl}- 626 IH-pyrazole-1-carboxarnide 5-cyclopropyl-N- (2-fluorobenzyl)-3- {2-hydroxy-4- [ (3- 627 methylbutanoyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclopropyl-N- (3-fluorobenzyl)-3- {2-hydroxy-4- [ (3- 628 methylbutanoyl) amino] phenyl}-IH-pyrazole-l-carboxamide N, 5-dicyclopropyl-3- {2-hydroxy-4- [ (3-methylbutanoyl) amino] phenyl}-lH- 629 pyrazole-1-carboxamide 5-cyclobutyl-N-ethyl-3- {2-hydroxy-4-[(3-methylbutanoyl) amino] phenyl}-1H- 630 pyrazole-l-carboxamide v 5-cyclobutyl-N-ethyl-3- {2-hydroxy-4- [ (3-methylbutanoyl) amino] phenyl}-lH- 631 pyrazole-l-carboxamide N-allyl-5-cyclobutyl-3- {2-hydroxy-4- [ (3-methylbutanoyl) amino] phenyl}-1H- 632 pyrazole-l-carboxamide 5-cyclobutyl-3- {2-hydroxy-4-[(3-methylbutanoyl) amino] phenyl}-N-propyl-lH- 633 pyrazole-1-carboxamide A N-benzyl-5-cyclobutyl-3- {2-hydroxy-4-[(3-methylbutanoyl) amino] phenyl}-1H- 634 pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-4- [ (3-methylbutanoyl) amino] phenyl}-N-(2- 635 phenylethyl)-1 H-pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-4-[(3-methylbutanoyl) amino] phenyl}-N-(2- 636 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {2-hydroxy-4- [ (3-methylbutanoyl) amino] phenyl}-N- (3- 637 methylbenzyl)-lH-pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-4-[(3-methylbutanoyl) amino] phenyl}-N-(4- 638 methylbenzyl)-1 H-pyrazole-1-carboxamide N- (2-chlorobenzyl)-5-cyclobutyl-3- {2-hydroxy-4- [ (3- 639 methylbutanoyl) amino henyl}-IH-pyrazole-l-carboxamide 5-cyclobutyl-N- (4-Ruorobenzyl)-3- {2-hydroxy-4- [ (3- 640 methylbutanoyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclobutyl-N-(3, 4-dichlorobenzyl)-3- {2-hydroxy-4-[(3- 641 methylbutanoyl) amino] phenyl}-1 H-pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-4- [ (3-methylbutanoyl) ammo] phenyI}-N- (4- 642 methoxybenzyl)-lH-pyrazole-l-carboxamide N- (sec-butyl)-5-cyclobutyl-3- {2-hydroxy-4- [ (3-methylbutanoyl) amino] phenyl}- 643 IH-pyrazole-1-carboxamide 5-cyclobutyl-N- (2-fluorobenzyl)-3- {2-hydroxy-4- [ (3- 644 methylbutanoyl) amino]phenyl}-1H-pyrazole-l-carboxamide 5-cyclobutyl-N- (3-fluorobenzyl)-3- {2-hydroxy-4- [ (3- 645 methylbutanoyl) amino] phenyl-lH-pyrazole-l-carboxamide 5-cyclobutyl-N-cyclopropyl-3-f2-hydroxy-4- [ (3-methylbutanoyl) amino] phenyl}- 646 1H-pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-4- [ (3-methylbutanoyl) amino] phenyl}-N-isopropyl- 647 1 H-pyrazole-I-carboxamide 5-cyclopentyl-N-ethyl-3- {2-hydroxy-4- [ (3-methylbutanoyl) amino] phenyl}-lH- 648 pyrazole-1-carboxamide N-allyl-5-cyclopentyl-3- {2-hydroxy-4-[(3-methylbutanoyl) amino] phenyl}-1H- 649 yrazole-1-carboxamide 5-cyclopentyl-3- 2-hydroxy-4- [ (3-methylbutanoyl) amino] phenyl}-N-propyl-lH- 650 pyrazole-1-carboxamide N-benzyl-5-cyclopentyl-3- {2-hydroxy-4-[(3-methylbutanoyl) amino] phenyl}-1H- 651 pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-4- [ (3-methylbutanoyl) amino] phenyl}-N- (2- 652 phenylethyl)-lH-pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-4- [ (3-methylbutanoyl) amino] phenyl}-N- (2- 653 methylbenzyl)-1H-pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-4- [ (3-methylbutanoyl) amino] phenyl}-N- (3- 654 methylbenzyl)-1 H-pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-4- [ (3-methylbutanoyl) amino] phenyl}-N-(4- 655 methylbenzyl)-lH-pyrazole-l-carboxamide N- (2-chlorobenzyl)-5-cyclopentyl-3- {2-hydroxy-4- [ (3- 656 methylbutanoyl) amino phenyl}-lH-pyrazole-l-carboxamide 5-cyclopentyl-N- (4-fluorobenzyl)-3- {2-hydroxy-4- [ (3- 657 methylbutanoyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclopentyl-N- (3, 4-dichlorobenzyl)-3- {2-hydroxy-4- [ (3- 658 methylbutanoyl) aminoXphenyl}-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {2-hydroxy-4- [ (3-methylbutanoyl) amino] phenyl}-N- (4- 659 methoxybenzyl)-lH-pyrazole-l-carboxamide N- (sec-butyl)-5-cyclopentyl-3- {2-hydroxy-4- [ (3-methylbutanoyl) amino] phenyl}- 660 1H-pyrazole-1-carboxamide 5-cyclopentyl-N- (2-fluorobenzyl)-3- {2-hydroxy-4- [ (3- 661 methylbutanoyl) aminogphenyl}-1 H-pyrazole-1-carboxamide 5-cyclopentyl-N- (3-fluorobenzyl)-3- {2-hydroxy-4- [ (3- 662 methylbutanoyl) amino] phenyl}-IH-pyrazole-1-carboxamide 5-cyclopentyl-N-cyclopropyl-3- {2-hydroxy-4- [ (3-methylbutanoyl) amino] phenyl}- 663 IH-pyrazole-l-carboxamide S-cyclopropyl-3-[2-hydroxy-4-(propionylamino) phenylJ-N-isopropyl-lH- 664 pyrazole-1-carboxamide 5-cyclopropyl-N-ethyl-3- [2-hydroxy-4- (propionylamino) phenyl]-lH-pyrazole-l- 665 carboxamide -allyl-5-cyclopropyl-3- [2-hydroxy-4- (propionylamino) phenyl]-lH-pyrazole-l- 666 carboxamide 5-cyclopropyl-3-[2-hydroxy-4-(propionylamino) phenyl]-N-propyl-lH-pyrazole-l- 667 carboxamide N-benzyl-5-cyclopropyl-3-[2-hydroxy-4-(propionylamino) phenyl]-lH-pyrazole-1- 668 carboxamide 5-cyclopropyl-3-[2-hydroxy-4-(propionylarnino) phenyl]-N-(2-phenylethyl)-lH- 669 pyrazole-1-carboxamide 5-cyclopropyl-3- [2-hydroxy-4- (propionylamino) phenyl]-N- (2-methylbenzyl)-1H- 670 pyrazole-l-carboxamide 5-cyclopropyl-3- [2-hydroxy-4- (propionylamino) phenyl]-N- (3-methylbenzyl)-lH- 671 pyrazole-I-carboxamide N, 5-dicyclopropyl-3- [2-hydroxy-4- (propionylamino) phenyl]-lH-pyrazole-l- 672 carboxamide N- (2-chlorobenzyl)-5-cyclopropyl-3- [2-hydroxy-4- (propionylamino) phenyl]-lH- 673 pyrazole-l-carboxamide 5-cyclopropyl-N- (4-fluorobenzyl)-3- [2-hydroxy-4- (propionylamino) phenyl]-lH- 674 pyrazole-1-carboxamide 5-cyclopropyl-N- (3, 4-dichlorobenzyl)-3- [2-hydroxy-4- (propionylamino) phenyl]- 675 1H-yrazole-1-carboxamide 5-cyclopropyl-3- [2-hydroxy-4- (propionylamino) phenyl]-N- (4-methoxybenzyl)- 676 IH-pyrazole-l-carboxamide N- (sec-butyl)-5-cyclopropyl-3- [2-hydroxy-4- (propionylamino) phenyl]-lH- 677 pyrazole-I-carboxamide 5-cyclopropyl-N-(2-fluorobenzyl)-3-[2-hydroxy-4-(propionylam ino) phenyl]-lH- 678 pyrazole-1-carboxamide 5-cyclopropyl-N-(3-fluorobenzyl)-3-[2-hydroxy-4-(propionylai nino) phenyl]-lH- 679 yrazole-1-carboxamide N, 5-dicyclopropyl-3-[2-hydroxy-4-(propionylarnino) phenyl]-lH-pyrazole-1- 680 carboxamide 5-cyclobutyl-3- [2-hydroxy-4- (propionylamino) phenyl]-N-isopropyl-lH-pyrazole- 681 1-carboxamide 5-cyclobutyl-N-ethyl-3- [2-hydroxy-4- (propionylamino) phenyl]-1 H-pyrazole-1- 682 carboxamide N-allyl-5-cyclobutyl-3-[2-hydroxy-4-(propionylamino) phenyl]-1 H-pyrazole-1- 683 carboxamide 5-cyclobutyl-3- [2-hydroxy-4- (propionylamino) phenyl]-N-propyl-lH-pyrazole-l- 684 carboxamide N-benzyl-5-cyclobutyl-3- [2-hydroxy-4- (propionylamino) phenyl]-lH-pyrazole-l- 685 carboxamide 5-cyclobutyl-3- [2-hydroxy-4- (propionylamino) phenyl]-N- (2-phenylethyl)-lH- 686 pyrazole-l-carboxamide 5-cyclobutyl-3- [2-hydroxy-4-(propionylamino) phenyl]-N-(2-methylbenzyl)-1 H- 687 pyrazole-1-carboxamide 5-cyclobutyl-3- [2-hydroxy-4- (propionylamino) phenyl]-N- (3-methylbenzyl)-1H- 688 pyrazole-1-carboxamide 5-cyclobutyl-3-[2-hydroxy-4-(propionylamino) phenyl3-N-(4-methylbenzyl)-lH- 689 pyrazole-l-carboxamide N- (2-chlorobenzyl)-5-cyclobutyl-3- [2-hydroxy-4- (propionylarnino) phenyl]-lH- 690 pyrazole-l-carboxamide 5-cyclobutyl-N- Ruorobenzyl)-3-[2-hydroxy-4-(propionylarnino) phenyl]-iH- 691 yrazole-1-carboxamide 5-cyclobutyl-N- (3, 4-dichlorobenzyl)-3- [2-hydroxy-4- (propionylamino) phenyl]- 692 IH-pyrazole-l-carboxamide 5-cyclobutyl-3- [2-hydroxy-4- (propionylamino) phenyl]-N- (4-methoxybenzyl)-lH- 693 pyrazole-l-carboxamide N- (sec-butyl)-5-cyclobutyl-3- [2-hydroxy-4- (propionylamino) phenyl]-lH- 694 pyrazole-1-carboxamide 5-cyclobutyl-N- (2-fluorobenzyl)-3- [2-hydroxy-4- (propionylamino) phenyl]-IH- 695 pyrazole-l-carboxamide 5-cyclobutyl-N- (3-fluorobenzyl)-3- [2-hydroxy-4- (propionylamino) phenyl]-lH- 696 pyrazole-1-carboxamide 5-cyclobutyl-N-cyclopropyl-3- [2-hydroxy-4- (propionylamino) phenyl]-lH- 697 pyrazole-l-carboxamide 5-cyclopentyl-3-[2-hydroxy-4-(propionylamino) phenyl]-N-isopropyl-lH-pyrazole- 698 1-carboxamide 5-cyclopentyl-N-ethyl-3-[2-hydroxy-4-(propionylamino) phenyl]-lH-pyrazole-l- 699 carboxamide N-allyl-5-cyclopentyl-3-[2-hydroxy-4-(propionylamino) phenylJ-lH-pyrazole-l- 700 carboxamide 5-cyclopentyl-3-[2-hydroxy-4-(propionylamino) phenyl]-N-propyl-lH-pyrazole-l- 701 carboxamide N-benzyl-5-cyclopentyl-3- [2-hydroxy-4- (propionylamino) phenyl]-lH-pyrazole-1- 702 carboxamide 5-cyclopentyl-3-[2-hydroxy-4-(propionylamino) phenyl]-N-(2-phenylethyl)-1 H- 703 pyrazole-l-carboxamide 5-cyclopentyl-3- [2-hydroxy-4- (propionylamino) phenyl]-N- (2-methylbenzyl)-lH- 704 pyrazole-l-carboxamide 5-cyclopentyl-3-[2-hydroxy-4-(propionylamino) phenyl]-N-(3-methylbenzyl)-lH- 705 pyrazole-1-carboxamide 5-cyclopentyl-3- [2-hydroxy-4- (propionylamino) phenyl]-N- (4-methylbenzyl)-lH- 706 pyrazole-1-carboxamide N- (2-chlorobenzyl)-5-cyclopentyl-3- [2-hydroxy-4- (propionylamino) phenyl]-lH- 707 pyrazole-l-carboxamide A 5-cyclopentyl-N-(4-fluorobenzyl)-3-[2-hydroxy-4-(propionylam ino) phenyl]-lH- 708 pyrazole-1-carboxamide 5-cyclopentyl-N-(3, 4-dichlorobenzyl)-3-[2-hydroxy-4-(propionylamino) phenyl]- 709 1H-yrazole-1-carboxamide 5-cyclopentyl-3- [2-hydroxy-4- (propionylamino) phenyl]-N- (4-methoxybenzyl)- 710 1H-pyrazole-1-carboxamide N- (sec-butyl)-5-cyclopentyl-3- [2-hydroxy-4- (propionylamino) phenyl]-IH- 711 pyrazole-l-carboxamide 5-cyclopentyl-N-(2-fluorobenzyl)-3-[2-hydroxy-4-(propionylam ino) phenyl]-lH- 712 pyrazole-l-carboxamide 5-cyclopentyl-N- (3-fluorobenzyl)-3- [2-hydroxy-4- (propionylamino) phenyl]-1H- 713 pyrazole-l-carboxamide 5-cyclopentyl-N-cyclopropyl-3- [2-hydroxy-4- (propionylamino) phenyl]-lH- 714 pyrazole-1-carboxamide 5-cyclopropyl-3- {4-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N- 715 isopropyl-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {4- [(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-ethyl-1 H- 716 pyrazole-1-carboxamide N-allyl-5-cyclopropyl-3- {4-[(cyclopropylcarbonyl) arnino]-2-hydroxyphenyl}-1H- 717 pyrazole-l-carboxamide 5-cyclopropyl-3- {4-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-propyl- 718 1H-pyrazole-1-carboxamide N-benzyl-5-cyclopropyl-3- {4-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}- 719 1H-pyrazole-1-carboxamide 5-cyclopropyl-3- 4- [ (cyclopropylcarbonyl) amino]-2-hydroxyphenyll-N- (2- 720 phenylethyl)-IH-pyrazole-1-carboxamide 5-cyclopropyl-3- {4-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-(2- 721 methylbenzyl)-lH-pyrazole-1-carboxamide 5-cyclopropyl-3- {4-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-(3- 722 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {4-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-(4- 723 methylbenzyl)-lH-pyrazole-l-carboxamide N-(2-chlorobenzyl)-5-cyclopropyl-3- {4-[(cyclopropylcarbonyl) amino]-2- 724 hydroxyphenyl}-lH-pyrazole-l-carboxarnide 5-cyclopropyl-3- {4-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-(4- 725 fluorobenzyl)-lH-pyrazole-1-carboxamide 5-cyclopropyl-3- {4- [ (cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N- (3, 4- 726 dichlorobenzyl)-1 H-pyrazole-1-carboxamide 5-cyclopropyl-3- {4-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-(4- 727 methoxybenzyl)-lH-pyrazole-l-carboxamide N-(sec-butyl)-5-cyclopropyl-3- {4-[(cyclopropylcarbonyl) amino]-2- 728 hydroxyphenyl}-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {4-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-(2- 729 fluorobenzyl)-1 H-pyrazole-1-carboxamide 5-cyclopropyl-3-14- [ (cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N- (3- 730 fluorobenzyl)-T H-pyrazole-1-carboxamide N, 5-dicyclopropyl-3- {4-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-1H- 731 yrazole-1-carboxamide 5-cyclobutyl-3-f{4- [ (cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-isopropyl- 732 IH-yrazole-l-carboxamide 5-cyclobutyl-3- {4- [ (cyclopropylcarbonyl) ammo]-2-hydroxyphenyl}-N-ethyl-1H- 733 pyrazole-1-carboxamide N-allyl-5-cyclobutyl-3- {4-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-lH- 734 pyrazole-1-carboxamide 5-cyclobutyl-3- {4-[(cyclopropylcarbonyl) arnino]-2-hydroxyphenyl}-N-propyl-lH- 735 pyrazole-1-carboxamide N-benzyl-5-cyclobutyl-3-{4-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-1H- 736 pyrazole-l-carboxamide 5-cyclobutyl-3- {4-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-(2- 737 phenylethyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {4-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-(2- 738 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {4-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-(3- 739 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {4- [ (cyclopropylcarbonyl) ammo]-2-hydroxyphenyl}-N- (4- 740 methylbenzyl)-lH-pyrazole-l-carboxamide N- (2-chlorobenzyl)-5-cyclobutyl-3- {4- [ (cyclopropylcarbonyl) amino]-2- 741 hydroxyphenyl-lH-pyrazole-l-carboxamide 5-cyclobutyl-3-f4- [ (cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N- (4- 742 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- 4- [ (cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N- (3, 4- 743 dichlorobenzyl)-lH-pyrazole-1-carboxamide 5-cyclobutyl-3- {4- [ (cyclopropylcarbonyl) amino]-2-hydroxyphenyl-N- (4- 744 methoxybenzyl)-lH-pyrazole-1-carboxamide N- (sec-butyl)-5-cyclobutyl-3- {4- [ (cyclopropylcarbonyl) amino]-2- 745 hydroxyphenyl}-1 H-pyrazole-1-earboxamide 5-cyclobutyl-3- {4- [ (cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N- (2- 746 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {4- [ (cyclopropylcarbonyl) ammo]-2-hydroxyphenyl}-N- (3- 747 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-N-cyclopropyl-3- {4- [ (cyclopropylcarbonyl) amino]-2- 748 hydroxyphenyl}-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {4-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-isopropyl- 749 1 H-pyrazole-1-earboxamide S-cyclopentyl-3- {4- [ (cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-ethyl-1H- 750 pyrazole-1-carboxamide N-allyl-5-cyclopentyl-3- {4- [ (cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-lH- 751 pyrazole-1-carboxamide 5-cyclopentyl-3- {4- [ (cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-propyl- 752 IH-pyrazole-l-carboxamide N-benzyl-5-eyelopentyl-3- {4-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}- 753 IH-pyrazole-l-carboxamide 5-cyclopentyl-3- {4-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-(2- 754 phenylethyl)-lH-pyrazole-1-carboxamide 5-cyclopentyl-3- {4-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-(2- 755 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {4- [ (cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N- (3- 756 methylbenzyl)-lH-pyrazole-l-carboxamide 5-eyelopentyl-3- {4-[(cyelopropylcarbonyl) amino]-2-hydroxyphenyl}-N-(4- 757 methylbenzyl)-lH-pyrazole-l-carboxamide N- (2-chlorobenzyl)-5-cyclopentyl-3- {4- [ (cyclopropylcarbonyl) amino]-2- 758 hydroxyphenyl}-lH-pyrazole-l-carboxaJnide 5-cyclopentyl-3- {4- [ (cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N- (4- 759 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {4- [ (cyclopropylcarbonyl) ammo]-2-hydroxyphenyl}-N- (3, 4- 760 dichlorobenzyl)-1 H-pyrazole-1-carboxamide 5-cyclopcntyl-3- {4- [ (cyclopropylcarbonyI) ammo]-2-hydroxyphenyl}-N- (4- 761 methoxybenzyl)-lH-pyrazole-1-carboxamide N- (sec-butyl)-5-cyclopentyl-3- {4- [ (cyclopropylcarbonyl) amino]-2- 762 hydroxyphenyl-IH-pyrazole-1-carboxamide 5-cyclopentyl-3- {4- [ (cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N- (2- 763 fluorobenzyl)-lH-pyrazole-1-earboxamide __ 5-cyclopentyl-3- {4-[(eyelopropylearbonyl) amino]-2-hydroxyphenyl}-N-(3- 764 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-N-cyclopropyl-3- {4- [ (cyclopropylcarbonyl) ammo]-2- 765 hydroxyphenyl-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-N-isopropyl-lH-pyrazole- 766 1-carboxamide 5-cyclopropyl-N-ethyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-lH-pyrazole-l- 767 carboxamide N-allyl-5-cyclopropyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-lH-pyrazole-l- 768 carboxamide 5-cyclopropyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-N-propyl-lH-pyrazole-l- 769 carboxamide N-benzyl-5-cyclopropyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-lH-pyrazole-l- 770 carboxamide 5-cyclopropyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-N- (2-phenylethyl)-1 H- 771 pyrazole-l-carboxamide 5-cyclopropyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-N- (2-methylbenzyl)-IH- 772 pyrazole-1-carboxamide 5-cyclopropyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-N- (3-methylbenzyl)-1H- 773 pyrazole-1-carboxamide 5-cyclopropyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-N- (4-methylbenzyl)-lH- 774 pyrazole-l-carboxamide N- (2-chlorobenzyl)-5-cyclopropyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-lH- 775 pyrazole-1-carboxamide 5-cyclopropyl-N- (4-fluorobenzyl)-3- [4- (2-furoylamino)-2-hydroxyphenyl]-1 H- 776 pyrazole-I-carboxamide 5-cyclopropyl-N- (3, 4-dichlorobenzyl)-3- [4- (2-furoylamino)-2-hydroxyphenyl]- 777 IH-pyrazole-1-carboxamide 5-cyclopropyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-N- (4-methoxybenzyl)-lH- 778 pyrazole-l-carboxamide N- (sec-butyl)-5-cyclopropyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-lH-pyrazole- 779 1-carboxamide 5-cyclopropyl-N- (2-fluorobenzyl)-3- [4- (2-furoylamino)-2-hydroxyphenyl]-lH- 780 pyrazole-l-carboxamide 5-cyclopropyl-N- (3-fluorobenzyl)-3- [4- (2-furoylamino)-2-hydroxyphenyl]-1 H- 781 pyrazole-1-carboxamide N, 5-dicyclopropyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-lH-pyrazole-l- 782 carboxamide 5-cyclobutyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-N-isopropyl-lH-pyrazole-l- 783 carboxamide 5-cyclobutyl-N-ethyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-lH-pyrazole-1- 784 carboxamide N-allyl-5-cyclobutyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-lH-pyrazole-l- 785 carboxamide 5-cyclobutyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-N-propyl-lH-pyrazole-1- 786 carboxamide N-benzyl-5-cyclobutyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-lH-pyrazole-l- 787 carboxamide 5-cyclobutyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-N- (2-phenylethyl)-lH- 788 pyrazole-l-carboxamide 5-cyclobutyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-N- (2-methylbenzyl)-lH- 789 yrazole-1-carboxamide 5-cyclobutyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-N- (3-methylbenzyl)-1 H- 790 pyrazole-1-carboxamide 5-cyclobutyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-N- (4-methylbenzyl)-lH- 791 yrazole-1-carboxamide A N- (2-chlorobenzyl)-5-cyclobutyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-lH- 792 pyrazole-l-carboxamide 5-cyclobutyl-N- (4-fluorobenzyl)-3- [4- (2-furoylamino)-2-hydroxyphenyl]-2 H- 793 pyrazole-l-carboxamide 5-cyclobutyl-N- (3, 4-dichlorobenzyl)-3- [4- (2-furoylamino)-2-hydroxyphenyl]-1H- 794 pyrazole-l-carboxamide 5-cyclobutyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-N- (4-methoxybenzyl)-lH- 795 pyrazole-l-carboxamide N- (sec-butyl)-5-cyclobutyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-lH-pyrazole- 796 1-carboxamide 5-cyclobutyl-N- (2-fluorobenzyl)-3- [4- (2-furoylamino)-2-hydroxyphenyl]-IH- 797 pyrazole-1-carboxamide 5-cyclobutyl-N- (3-fluorobenzyl)-3- [4- (2-furoylamino)-2-hydroxyphenyl]-lH- 798 pyrazole-1-carboxamide . 5-cyclobutyl-N-cyclopropyl-3-[4-(2-furoylamino)-2-hydroxyphe nyl]-lH-pyrazole- 799 1-carboxamide 5-cyclopentyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-N-isopropyl-lH-pyrazole- 800 1-carboxamide 5-cyclopentyl-N-ethyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-lH-pyrazole-1- 801 carboxamide N-allyl-5-cyclopentyl-3- [4- H-pyrazole-1- 802 carboxamide 5-cyclopentyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-N-propyl-lH-pyrazole-l- 803 carboxamide 5-cyclopentyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-N- (2-methylbenzyl)-lH- 804 pyrazole-l-carboxamide 5-cyclopentyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-N- (2-phenylethyl)-lH- 805 pyrazole-l-carboxamide 5-cyclopentyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-N- (2-methylbenzyl)-lH- 806 pyrazole-1-carboxamide 5-cyclopentyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-N- (3-methylbenzyl)-1 H- 807 yrazole-l-carboxamide A 5-cyclopentyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-N- (4-methylbenzyl)-lH- 808 pyrazole-1-carboxamide N- (2-chlorobenzyl)-5-cyclopentyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-1 H- 809 pyrazole--carboxamide 5-cyclopentyl-N- (4-fluorobenzyl)-3- [4- (2-furoylamino)-2-hydroxyphenyl]-1 H- 810 pyrazole-1-carboxamide 5-cyclopentyl-N- (3, 4-dichlorobenzyl)-3- [4- (2-furoylamino)-2-hydroxyphenyl]- 811 IH-pyrazole-l-carboxamide 5-cyclopentyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-N- (4-methoxybenzyl)-lH- 812 pyrazole-1-carboxamide N- (sec-butyl)-5-cyclopentyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-IH-pyrazole- 813 1-carboxamide 5-cyclopentyl-N- (2-fluorobenzyl)-3- [4- (2-furoylamino)-2-hydroxyphenyl]-lH- 814 pyrazole-l-carboxamide 5-cyclopentyl-N- (3-fluorobenzyl)-3- [4- (2-furoylamino)-2-hydroxyphenyl]-lH- 815 pyrazole-1-carboxamide 5-cyclopentyl-N-cyclopropyl-3- [4- (2-furoylamino)-2-hydroxyphenyl]-lH- 816 pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-4-[(thien-2-ylcarbonyl) amino] phenyl}-N-isopropyl- 817 IH-pyrazole-l-carboxarnide 5-cyclopropyl-N-ethyl-3- {2-hydroxy-4-[(thien-2-ylcarbonyl) axnino] phenyl}-1H- 818 pyrazole-1-carboxamide N-allyl-5-cyclopropyl-3- {2-hydroxy-4-[(thien-2-ylcarbonyl) amino] phenyl}-lH- 819 pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-4- [ (thien-2-ylcarbonyl) amino] phenyl}-N-propyl-lH- 820 pyrazole-1-carboxamide N-benzyl-5-cyclopropyl-3- {2-hydroxy-4-[(thien-2-ylcarbonyl) amino] phenyl}-lH- 821 pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-4-[(thien-2-ylcarbonyl) arnino] phenyl}-N-(2- 822 phenylethyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {2-hydroxy-4-[(thien-2-ylcarbonyl) amino] phenyl}-N-(2- 823 methylbenzyl)-1 H-pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-4- [ (thien-2-ylcarbonyl) amino] phenyl}-N- (3- 824 methylbenzyl)-1 H-pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-4-[(thien-2-ylcarbonyl) amino] phenyl}-N-(4- 825 methylbenzyl)-lH-pyrazole-l-carboxamide N- (2-chlorobenzyl)-5-cyclopropyl-3- {2-hydroxy-4- [ (thien-2- 826 ylcarbonyl) aminolphenyl}-lH-pyrazole-l-carboxamide 5-cyclopropyl-N-(4-fluorobenzyl)-3- {2-hydroxy-4-[(thien-2- 827 ylcarbonyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclopropyl-N- (3, 4-dichlorobenzyl)-3- {2-hydroxy-4- [ (thien-2- 828 ylcarbonyl) amino] phenyl}-IH-pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-4- [ (thien-2-ylcarbonyl) amino] phenyl}-N- (4- 829 methoxybenzyl)-lH-pyrazole-l-carboxamide N-(sec-butyl)-5-cyclopropyl-3- {2-hydroxy-4-[(thien-2-ylcarbonyl) amino] phenyl}- 830 lH-pyrazole-1-carboxamide 5-cyclopropyl-N- (2-fluorobenzyl)-3- f 2-hydroxy-4- [ (thien-2- 831 ylcarbonyl) amino] phenyl-lH-pyrazole-l-carboxamide 5-cyclopropyl-N- (3-fluorobenzyl)-3- {2-hydroxy-4- [ (thien-2- 832 ylcarbonyl) amino phenyl-lH-pyrazole-l-carboxamide N, 5-dicyclopropyl-3- {2-hydroxy-4-[(thien-2-ylcarbonyl) aminogphenyl}-lH- 833 pyrazole-l-carboxamide 5-cyclobutyl-3- {2-hydroxy-4-[(ien-2-ylcarbonyl) amino] phenyl}-N-isopropyl- 834 IH-pyrazole-l-carboxamide 5-cyclobutyl-N-ethyl-3- {2-hydroxy-4- [(ien-2-ylcarbonyl) ani no] phenyl}-1 H- 835 pyrazole-l-carboxamide N-allyl-5-cyclobutyl-3- {2-hydroxy-4- [ (thien-2-ylcarbonyl) amino] phenyl}-1H- 836 pyrazole-l-carboxamide 5-cyclobutyl-3- {2-hydroxy-4-[(thiën-2-ylcarbonyl) aminoXphenyl}-N-propyl-lH 837 pyrazole-1-carboxamide N-benzyl-5-cyclobutyl-3- {2-hydroxy-4-[(thien-2-ylcarbonyl) amino] phenyl}-lH- 838 yrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-4- [ (thien-2-ylcarbonyl) ammo] phenyl}-N- (2- 839 phenylethyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {2-hydroxy-4-[(thien-2-ylcarbonyl) atnino] phenyl}-N-(2- 840 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {2-hydroxy-4-[(thien-2-ylcarbonyl) amino] phenyl3-N-(3- 841 methylbenzyl)-lH-pyrazole-1-carboxatnide 5-cyclobutyl-3- {2-hydroxy-4-[(thien-2-ylcarbonyl) atnino] phenyl}-N-(4- 842 methylbenzyl)-lH-pyrazole-l-carboxamide N-(2-chlorobenzyl)-5-cyclobutyl-3- {2-hydroxy-4-[(thien-2- 843 ylcarbonyl) amino phenyl}-lH-pyrazole-l-carboxamide 5-cyclobutyl-N- (4-fluorobenzyl)-3- {2-hydroxy-4- [ (thien-2- 844 ylcarbonyl) amino] phenyl}-1 H-pyrazole-1-carboxamide 5-cyclobutyl-N- (3, 4-dichlorobenzyl)-3- {2-hydroxy-4-[(thien-2- 845 ylcarbonyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {2-hydroxy-4- [(thien-2-ylcarbonyl) arnino] phenyl}-N-(4- 846 methoxybenzyl)-lH-pyrazole-1-carboxamide .. N-(sec-butyl)-5-cyclobutyl-3- {2-hydroxy-4-[(thien-2-ylcarbonyl) arnino] phenyl}- 847 1 H-pyrazole-1-carboxamide 5-cyclobutyl-N-(2-fluorobenzyl)-3- {2-hydroxy-4-[(thien-2- 848 ylcarbonyl) amino henyl}-1H-pyrazole-1-carboxamide 5-cyclobutyl-N-(3-fluorobenzyl)-3- {2-hydroxy-4-[(thien-2- 849 ylcarbonyl) amino henyl}-IH-pyrazole-1-carboxamide 5-cyclobutyl-N-cyclopropyl-3- {2-hydroxy-4-[(thien-2-ylcarbonyl) amino] phenyl}- 850 lH-pyrazole-l-carboxarnide A 5-cyclopentyl-3- {2-hydroxy-4- [(thien-2-ylcarbonyl) arnino] phenyl}-N-isopropyl- 851 1H-pyrazole-l-carboxamide 5-cyclopentyl-N-ethyl-3- {2-hydroxy-4-[(thien-2-ylcarbonyl) amino] phenyl}-lH- 852 pyrazole-l-carboxamide N-allyl-5-cyclopentyl-3- {2-hydroxy-4-[(thien-2-ylcarbonyl) arnino] phenyl}-1H- 853 pyrazole-l-carboxamide 5-cyclopentyl-3-{2-hydroxy-4-[(thien-2-ylcarbonyl) amino] phenyl}-N-propyl-lH- 854 pyrazole-l-carboxamide N-benzyl-5-cyclopentyl-3- {2-hydroxy-4-[(thien-2-ylcarbonyl) amino] phenyl}-1H- 855 pyrazole-l-carboxamide 5-cyclopentyl-3-{2-hydroxy-4-[(thien-2-ylcarbonyl) amino] phenyl}-N- (2- 856 henylethyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {2-hydroxy-4-[(thien-2-ylcarbonyl) arnino] phenyl}-N-(2- 857 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {2-hydroxy-4-[(thien-2-ylcarbonyl) amino] phenyl}-N-(3- 858 methylbenzyl)-1 H-pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-4-[(thien-2-ylcarbonyl) amino] phenyl}-N-(4- 859 methylbenzyl)-lH-pyrazole-l-carboxamide N-(2-chlorobenzyl)-5-cyclopentyl-3- {2-hydroxy-4-[(thien-2- 860 ylcarbonyl) amino phenyl-lH-pyrazole-1-carboxamide 5-cyclopentyl-N- (4-fluorobenzyl)-3-12-hydroxy-4- [ (thien-2- 861 ylcarbonyl) amino] phenyl}-1H-azole-l-carboxamide 5-cyclopentyl-N- (3, 4-dichlorobenzyl)-3- f2-hydroxy-4- [ (thien-2- 862 ylcarbonyl) amino henyl}-IH-pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-4- [ (thien-2-ylcarbonyl) amino] phenyl}-N- (4- 863 methoxybenzyl)-lH-pyrazole-l-carboxamide N-(sec-butyl)-5-cyclopentyl-3- {2-hydroxy-4-[(thien-2-ylcarbonyl) amino] phenyl}- 864 1H-pyrazole-l-carboxamide 5-cyclopentyl-N-(2-fluorobenzyl)-3- {2-hydroxy-4-[(thien-2- 865 ylcarbonyl) amino] phenyl-IH-pyrazole-1-carboxamide 5-cyclopentyl-N- (3-fluorobenzyl)-3- f 2-hydroxy-4- [ (thien-2- 866 ylcarbonyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclopentyl-N-cyclopropyl-3- {2-hydroxy-4-[(thien-2- 867 ylcarbonyl) amino] phenyl}-1 H-pyrazole-1-carboxamide N- {5-cyclopropyl-1-[(isopropylamino) carbonyl]-lH-pyrazol-3-yl}-3- 868 hydroxyphenyl) quinoxaline-2-carboxamide N- {5-cyclopropyl-1-[(ethylamino) carbonyl]-lH-pyrazol-3-yl}-3- 869 hydroxyphenyl) quinoxaline-2-carboxamide N-(4- {1-[(allylamino) carbonyl]-5-cyclopropyl-lH-pyrazol-3-yl}-3- 870 hydroxyphenyl) quinoxaline-2-carboxamide N- {5-cyclopropyl-1-[(propylatnino) carbonyl]-lH-pyrazol-3-yl}-3- 871 hydroxyphenyl) quinoxaline-2-carboxamide N- {1-[(benzylamino) carbonyl]-5-cyclopropyl-lH-pyrazol-3-yl}-3- 872 hydroxyphenyl) quinoxaline-2-carboxamide N- [4- (5-cyclopropyl-l- { [ (2-phenylethyI) amino] carbonyl}-lH-pyrazol-3-yl)-3- 873 hydroxyphenyl] quinoxaline-2-carboxamide N- [4- (5-cyclopropyl-1- { [ (2-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 874 hydroxyphenyl]quinoxaline-2-carboxamide N- [4- (5-cyclopropyl-l- { [ (3-methylbenzyl) ammo] carbonyl}-lH-pyrazol-3-yl)-3- 875 hydroxyphenyl] quinoxaline-2-carboxamide A a s _ N- [4- (5-cyclopropyl-l- { [ (4-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yI)-3- 876 hydroxyphenyl] quinoxaline-2-carboxamide a N- [4- (1- { [ (2-chlorobenzyl) amino] carbonyl}-5-cyclopropyl-lH-pyrazol-3-yl)-3- 877 hydroxyphenyl uinoxaline-2-carboxamide N- [4- (5-cyclopropyl-1- { [ (4-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 878 hydroxyPhenyl. l auinoxaline-2-carboxamide v N- [4- (5-cyclopropyl-l-f [ (3, 4-dichlorobenzyl) amino] carbonyl}-1 H-pyrazol-3-yl)- 879 3-hydroxyphenyl] quinoxaline-2-carboxamide N- [4- (5-cyclopropyl-1- {[ (4-methoxybenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 880 hydroxyphenyl] uinoxaline-2-carboxamide N-(4- {1-f (sec-butylamino) carbonyl]-5-cyclopropyl-lH-pyrazol-3-yl}-3- hydroxyphenyl) quinoxaline-2-carboxamide N- [4- (5-cyclopropyl-l- { [ (2-fluorobenzyl) amino] carbonyl}-IH-pyrazol-3-yl)-3- 882 hydrox henyl] uinoxaline-2-carboxamide N- [4- (5-cyclopropyl-1-1 [ (3-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 883 hydroxyPhenyl3uuinoxaline-2-carboxamide N-(4- {5-cyclopropyl-1-[(cyclopropylamino) carbonyl]-lH-pyrazol-3-yl}-3- 884 hydroxyphenyl) uinoxaline-2-carboxamide N-(4- {5-cyclobutyl-1- [(isopropylamino) carbonyl]-1 H-pyrazol-3-yl}-3- 885 hydroxyphenyl) uinoxaline-2-carboxamide N- (4- {5-cyclobutyl-l- [ (ethylammo) carbonyl]-lH-pyrazol-3-yl}-3- 886 hydroxyphenyl) quinoxaline-2-carboxamide N- (4- {1- [ (allylamino) carbonyl]-5-cyclobutyl-lH-pyrazol-3-yl}-3- 887 hydroxyphenyl) uinoxaline-2-carboxamide N- {5-cyclobutyl-1-[(propylamino) carbonyl]-lH-pyrazol-3-yl}-3- 888 hydroxyphenyl) quinoxaline-2-carboxamide _ _ N- {1-[(benzylamino) carbonyl]-5-cyclobutyl-1 H-pyrazol-3-yl}-3- 889 hydroxyphenyl) quinoxaline-2-carboxamide N- [4- (5-cyclobutyl-l- { [ (2-phenylethyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 890 hydroxyphenyl] quinoxaline-2-carboxamide N- [4- (5-cyclobutyl-l- { [ (2-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 891 hydroxyphenyl] quinoxaline-2-carboxamide - [4- (5-evelobtityl-l-f [ (3-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 892 hydroxyphenyl] quinoxaline-2-carboxamide N- [4- (5-cyclobutyl-l- { [ (4-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 893 hydroxyphenyl] quinoxaline-2-carboxamide - [4- (I-I [ (2-chlorobenzyl) aminolcarbonyl)-5-cyclobutyl-IH-pyrazol-3-yl)-3- 894 hydroxyphenyl] uinoxaline-2-carboxamide N- [4- (5-cyclobutyl-l- { [ (4-Suorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 895 hydroxyphenyl] quinoxaline-2-carboxamide N- [4- (5-cyclobutyl-l- { [ (3, 4-dichlorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 896 hydroxyphenyl] quinoxaline-2-carboxamide N- [4- (5-cyclobutyl-l- { [ (4-methoxybenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 897 hydroxyphenyl] quinoxaline-2-carboxamide N- {1-[(sec-butylamino) carbonyl]-5-cyclobutyl-lH-pyrazol-3-yl}-3- 898 hydroxyphenyl) uinoxaline-2-carboxamide A A N- [4- (5-cyclobutyl-l- { [ (2-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 899 hydroxyphenyl] quinoxaline-2-carboxamide N- [4- (5-cyclobutyl-1-1 [ (3-fluorobenzyI) amino] carbonyl}-IH-pyrazol-3-yl)-3- 900 hydroxyphenyl] quinoxaline-2-carboxamide A N- {5-cyclobutyl-1-E (cyclopropylamino) carbonyl]-lH-pyrazol-3-yl}-3- 901 hydroxyphenyl) quinoxaline-2-carboxamide N-(4- {5-cyclopentyl-1-[(isopropylamino) carbonyl]-lH-pyrazol-3-yl}-3- 902 hydroxyphenyl) quinoxaline-2-carboxamide N- (4- {5-cyclopentyl-l- [ (ethylammo) carbonyl]-lH-pyrazol-3-yl}-3- 903 hydroxyphenyl) quinoxaline-2-carboxamide N- (4- 1- [ (allylamino) carbonyl]-5-cyclopentyl-IH-pyrazol-3-yl}-3- 904 hydroxyphenyl) quinoxaline-2-carboxamide N-(4-{5-cyclopentyl-1-[(propylamino) carbonyl]-lH-pyrazol-3-yl}-3- 905 hydroxyphenyl) quinoxaline-2-carboxamide N-(4-{1-[(benzylamino) carbonyl]-5-cyclopentyl-lH-pyrazol-3-yl}-3- 906 hydroxyphenyl) quinoxaline-2-carboxamide N- [4- (5-cyclopentyl-1- { [ (2-phenylethyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 907 hydroxyphenyl] quinoxaline-2-carboxamide N- [4- (5-cyclopentyl-l- { [ (2-methylbenzyI) amino] carbonyl}-lH-pyrazol-3-yl)-3- 908 hydroxyphenyl] quinoxaline-2-carboxamide _ _ N- [4- (5-cyclopentyl-l- { [ (3-methylbenzyl) amiiio] carbonyl}-lH-pyrazol-3-yl)-3- 909 hydroxyphenyl] quinoxaline-2-carboxamide N-[4-(5-cyclopentyl-1- {[(4-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 910 hydroxyphenyl uinoxaline-2-carboxamide N- [4- (l- { [ (2-chlorobenzyl) amino] carbonyl}-5-cyclopentyl-lH-pyrazol-3-yl)-3- 911 hydroxyphenyl] quinoxaline-2-carboxarnide N- [4- (5-cyclopentyl-l- { [ (4-iluorobenzyl) ammo] carbonyl}-lH-pyrazol-3-yl)-3- 912 hydroxyphenyl] uinoxaline-2-carboxarnide N- [4- (5-cyclopentyl-l-f [ (3, 4-dichlorobenzyl) amino] carbonyl}-1 H-pyrazol-3-yl)- 913 3-hydroxyphenyl] quinoxaline-2-carboxamide N- [4- (5-cyclopcntyl-l- { [ (4-methoxybenzyl) ammo] carbonyl}-lH-pyrazol-3-yl)-3- 914 hydroxyphenyl] uinoxaline-2-carboxamide N- {1-[(sec-butylamino) carbonyl]-5-cyclopentyl-lH-pyrazol-3-yl}-3- 915 hydroxyphenyl) quinoxaline-2-carboxamide N- [4- (5-cyclopentyl-1- f [ (2-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 916 hydroxyphenyl] quinoxaline-2-carboxamide N- [4- (5-cyclopentyl-1- {[ (3-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 917 hydroxyphenyl] quinoxaline-2-carboxamide N-(4- {5-cyclopentyl-1- [(cyclopropylamino) carbonyl]-l H-pyrazol-3-yl}-3- 918 hydroxyphenyl) quinoxaline-2-carboxamide N-(4- {5-cyclopropyl-1-[(isopropylaxnino) carbonyl]-lH-pyrazol-3-yl}-3- 919 hydroxyphenyl) nicotinamide N- (4- {5-cyclopropyl-1- [ (ethylamino) carbonyl]-lH-pyrazol-3-yl}-3- 920 hydroxyphenyl) nicotinamide N- (4- {l- [ (allylammo) carbonyl]-5-cyclopropyl-lH-pyrazol-3-yl}-3- 921 hydroxyphenyl) nicotinamide N-(4- {5-cyclopropyl-1-[(propylarnino) carbonyl]-lH-pyrazol-3-yl}-3- 922 hydroxyphenyl) nicotinamide N- (4- {1- [ (benzylammo) carbonyl]-5-cyclopropyl-lH-pyrazol-3-yl}-3- 923 hydroxyphenyl) nicotinamide N- [4- (5-cyclopropyl-1- { [ (2-phenylethyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 924 hydroxyphenyl] nicotinamide N- [4- (5-cyclopropyl-1-1 [ (2-methylbenzyl) mnino] carbonyll-lH-pyrazol-3-yl)-3- 925 hydroxyphenyljnicotinamide N- [4- (5-cyclopropyl-l- { [ (3-methylbemyl) amino] carbonyl}-1 H-pyrazol-3-yl)-3- 926 hydroxyphenyl] nicotinamide N- [4- (5-cyclopropyl-l- { [ (4-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 927 hydroxyphenyl nicotinamide N- [4- (l- { [ (2-chlorobenzyl) ammo] carbonyl}-5-cyclopropyl-lH-pyrazol-3-yl)-3- 928 hydroxyphenyl] nicotinamide N- [4- (5-cyclopropyl-l- { [ (4-iluorobenzyl) ammo] carbonyl}-lH-pyrazol-3-yl)-3- 929 hydroxyphenyl] nicotinamide N- [4- (5-cyclopropyl-1-1 [ (3, 4-dichlorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)- 930 3-hydroxyphenyl] nicotinamide N- [4- (5-cyclopropyl-l-f [ (4-methoxybenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 931 hydroxyphenyl] nicotinamide N- (4- {1- [ (sec-butylamino) carbonyl]-5-cyclopropyl-1 H-pyrazol-3-yl}-3- 932 hydroxyphenyl) nicotinamide N- [4- (5-cyclopropyl-1- { [ (2-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 933 hydroxyphenyl] nicotinamide N- [4- (5-cyclopropyl-1-1 [ (3-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 934 hydroxyphenyl] nicotinamide N-(4- {5-cyclopropyl-1-[(cyclopropylatnino) carbonyl]-lH-pyrazol-3-yl}-3- 935 hydroxyphenyl) nicotinamide N- {5-cyclobutyl-1-[(isopropylamino) carbonyl]-lH-pyrazol-3-yl}-3- 936 hydroxyphenyl) nicotinamide N- (4- {5-cyclobutyl-1- [ (ethylamino) carbonyl]-lH-pyrazol-3-yl}-3- 937 hydroxyphenyl) nicotinamide N-(4- {1-[(allylarnino) carbonyl]-5-cyclobutyl-lH-pyrazol-3-yl}-3- 938 hydroxyphenyl) nicotinamide N-(4- {5-cyclobutyl-1-[(propylamino) carbonyl]-lH-pyrazol-3-yl}-3- 939 hydroxyphenyl) nicotinamide N- {1-[(benzylamino) carbonyl]-5-cyclobutyl-lH-pyrazol-3-yl}-3- 940 hydroxyphenyl) nicotinamide N- [4- (5-cyclobutyl-1- { [ (2-phenylethyl) amino] carbonyl}-1 H-pyrazol-3-yl)-3- 941 hydroxyphenyl] nicotinamide N- [4- (5-cyclobutyl-l- { [ (2-methylbenzyl) amino] carbonyl}-IH-pyrazol-3-yl)-3- 942 hydroxyphenyljnicotinamide N- [4- (5-cyclobutyl-l- { [ (3-methylbenzyI) amino] carbonyl}-lH-pyrazol-3-yl)-3- 943 hydroxyphenyl] nicotinamide N- [4- (5-cyclobutyl-I- { [ (4-metliylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 944 hydroxyphenyl] nicotinamide N- [4- (l- { [ (2-chlorobenzyl) amino] carbonyl}-5-cyclobutyl-lH-pyrazol-3-yl)-3- 945 hydrox henyl] nicotinamide N- [4- (5-cyclobutyl-1- {[ (4-fluorobenzyl) amino] carbonyl}-1H-pyrazol-3-yl)-3- 946 hydroxyphenyl] nicotinamide N- [4- (5-cyclobutyl-1- { [ (3, 4-dichlorobenzyl) ammo] carbonyl}-1 H-pyrazol-3-yl)-3- 947 hydroxyphenyl] nicotinamide N- [4- (5-cyclobutyl-1- {[ (4-methoxybenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 948 hydroxyphenyl] nicotinamide N- {1-[(sec-butylamino) carbonyl]-5-cyclobutyl-lH-pyrazol-3-yl}-3- 949 hydroxyphenyl) nicotinamide N- [4- (5-cyclobutyl-1- { [ (2-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 950 hydroxyphenyl] nicotinarnide N- [4- (5-cyclobutyl-l- { [ (3-iluorobenzyl) ammo] carbonyl}-lH-pyrazol-3-yl)-3- 951 hydroxyphenyl] nicotinamide N- (4- {5-cyclobutyl-l- [ (cyclopropylamino) carbonyl]-lH-pyrazol-3-yl}-3- 952 hydroxyphenyl) nicotinamide N-(4-{5-cyclopentyl-1-[(isopropylamino) carbonyl]-lH-pyrazol-3-yl}-3- 953 hydroxyphenyl) nicotinamide N-(4-{5-cyclopentyl-1-[(ethylamino) carbonyl]-lH-pyrazol-3-yl3-3- 954 hydroxyphenyl) nicotinamide N- {1-[(allylamino) carbonyl]-5-cyclopentyl-lH-pyrazol-3-yl}-3- 955 hydroxyphenyl) nicotinamide N- {5-cyclopentyl-1-[(propylamino) carbonyl]-lH-pyrazol-3-yl}-3 956 hydroxyphenyl) nicotinamide N-(4-{1-[(benzylamino) carbonyl]-5-cyclopentyl-lH-pyrazol-3-yl}-3 957 hydroxyphenyl) nicotinamide N- [4- (5-cyclopentyl-l- { [ (2-phenylefhyl) ammo] carbonyl}-lH-pyrazol-3-yl)-3- 958 hydroxyphenyl] nicotinamide N- [4- (5-cyclopentyl-l- { [ (2-methylbenzyl) ammo] carbonyl}-lH-pyrazol-3-yl)-3- 959 hydroxyphenyl] nicotinamide N- [4- (5-cyclopentyl-I- { [ (3-methylbenzyl) amino] carbonyl}-I H-pyrazol-3-yl)-3- 960 hydroxyphenyl] nicotinamide N- [4- (5-cyclopentyl- I-f [ (4-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 961 hydroxyphenyl] nicotinamide N- [4- (l- {[ (2-chlorobenzyl) amino] carbonyl}-5-cyclopentyl-lH-pyrazol-3-yl)-3- 962 hydroxyphenyl] nicotinarnide N- [4- (5-cyclopentyl-1- { [ (4-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 963 hydroxyphenyljmcotmamide N-[4-(5-cyclopentyl-1- {[(3, 4-dichlorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)- 964 3-hydroxyphenyl] nicotinamide N- (4- {l- [ (sec-butylamino) carbonyl]-5-cyclopentyl-lH-pyrazol-3-yl}-3- 965 hydroxyphenyl) nicotinamide N- {1-[(sec-butylarnino) carbonyl]-5-cyclopentyl-lH-pyrazol-3-yl}-3- 966 hydroxyphenyl) nicotinamide . N- [4- (5-cyclopentyl-l- [ (2-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 967 hydroxyphenyl] nicotinamide N- [4- (5-cyclopentyl-1- {[ (3-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 968 hydroxyphenyljnicotinamide N- {5-cyclopentyl-1-[(cyclopropylamino) carbonyl]-lH-pyrazol-3-yl}-3- 969 hydroxyphenyl) nicotinamide N-(4- {5-cyclopropyl-1-[(isopropylarnino) carbonyl]-1 H-pyrazol-3-yl}-3- 970 hydroxyphenyl) isonicotinamide N- {5-cyclopropyl-1- [(ethylamino) carbonyl]-1 H-pyrazol-3-yl}-3- 971 hydroxyphenyl) isonicotinamide N- {1-[(allylamino) carbonyl]-5-cyclopropyl-lH-pyrazol-3-yl}-3- 972 hydroxyphenyl) isonicotinamide N- (4- {5-cyclopropyl-l- [ (propylamino) carbonyl]-lH-pyrazol-3-yl}-3- 973 hydroxyphenyl) isonicotinamide N-(4- {1-[(benzylamino) carbonyl]-5-cyclopropyl-1 H-pyrazol-3-yl}-3- 974 hydroxyphenyl) isonicotinamide N- [4- (5-cyclopropyl-l- { [ (2-phenylethyl) ammo] carbonyl}-lH-pyrazol-3-yl)-3- 975 hydroxyphenyl] isonicotinamide N- [4- (5-cyclopropyl-1- {[ (2-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 976 hydroxyphenyl] isonicotinamide N- [4- (5-cyclopropyl-l- { [ (3-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 977 hydroxyphenyljisonicotinamide N- [4- (5-cyclopropyl-1-1 [ (4-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 978 hydroxyphenyl] isonicotinamide N- [4- (l- { [ (2-chlorobenzyl) aminocarbonyl}-5-cyclopropyl-lH-pyrazol-3-yl)-3- 979 hydroxyphenyljisonicotinamide N- [4- (5-cyclopropyl-1- [ (4-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 980 hydroxyphenyl] isonicotinamide N- [4- (5-cyclopropyl-1-1 [ (3, 4-dichlorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)- 981 3-hydroxyphenyl] isonicotinamide N- [4- (5-cyclopropyl-l- { [ (4-methoxybenzyl) amino] carbonyl}-lH-pyrazol-3-yI)-3- 982 hydroxyphenyl] isonicotinamide N-(4- {1-[(sec-butylamino) carbonyl]-5-cyclopropyl-1 H-pyrazol-3-yl}-3- 983 hydroxyphenyl) isonicotinamide N- [4- (5-cyclopropyl-1- [ (2-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 984 hydroxyphenyl] isonicotinamide N- [4- (5-cyclopropyl-1- { [ (3-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 985 hydroxyphenyl isonicotinamide N- {5-cyclopropyl-1-[(cyclopropylamino) carbonyl]-lH-pyrazol-3-yl}-3- 986 hydroxyphenyl) isonicotinamide N-(4- {5-cyclobutyl-1-[(isopropylamino) carbonyl]-lH-pyrazol-3-yl}-3- 987 hydroxyphenyl) isonicotinamide N-(4- {5-cyclobutyl-1-[(ethylamino) carbonyl]-lH-pyrazol-3-yl}-3- 988 hydroxyphenyl) isonicotinamide N- (4- {1- [ (allylamino) carbonyl]-5-cyclobutyl-lH-pyrazol-3-yl}-3- 989 hydroxyphenyl) isonicotinamide N-(4- {5-cyclobutyl-1-[(propylarnino) carbonyl]-lH-pyrazol-3-yl}-3- 990 hydroxyphenyl) isonicotinamide N-(4- {1-[(benzylamino) carbonyl]-5-cyclobutyl-lH-pyrazol-3-yl}-3- 991 hydroxyphenyl) isonicotinamide N- [4- (5-cyclobutyl-1- { [ (2-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 992 hydroxyphenyl] isonicotinamide N- [4- (5-cyclobutyl-l-f [ (2-methylbenzyl) amino] carbonyl)-IH-pyrazol-3-yl)-3- 993 hydroxyphenyljisonicotinamide N- [4- (5-cyclobutyl-1-1 [ (3-methylbenzyl) aminolcarbonyll-lH-pyrazol-3-yl)-3- 994 hydroxyphenyl] isonicotinamide N- [4- (5-cyclobutyl-l- { [ (4-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 995 hydroxyphenyljisonicotinamide N- [4- (I- { [ (2-chlorobenzyl) amino] carbonyl}-5-cyclobutyl-lH-pyrazol-3-yl)-3- 996 hydroxyphenyl] isonicotinamide N- [4- (5-cyclobutyl-1-1 [ (4-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 997 hydroxyphenyl] isonicotinamide N- [4- (5-cyclobutyl-l- { [ (3, 4-dichlorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 998 hydroxyphenyl] isonicotinamide N-[4-(5-cyclobutyl-1- {[(4-methoxybenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 999 hydroxyphenyl] isonicotinamide N- (4- {l- [ (sec-butylaimno) carbonyl]-5-cyclobutyl-lH-pyrazol-3-yl}-3- 1000 hydroxyphenyl) isonicotinamide _ _ N- [4- (5-cyclobutyl-1- f [ (2-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 1001 hydroxyphenyl] isonicotinamide N- [4- (5-cyclobutyl-l- { [ (3-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 1002 hydroxyphenyl] isonicotinamide N-(4- {5-cyclobutyl-1-[(cyclopropylarnino) carbonyl]-lH-pyrazol-3-yl}-3- 1003 hydroxyphenyl) isonicotinamide N-(4- {5-cyclopentyl-1-[(isopropylamino) carbonyl]-lH-pyrazol-3-yl}-3- 1004 hydroxyphenyl) isonicotinamide N-(4- {5-cyclopentyl-1-[(ethylamino) carbonyl]-lH-pyrazol-3-yl}-3- 1005 hydroxyphenyl) isonicotinamide N- (4- {1- [ (allylamino) carbonyl]-5-cyclopentyl-lH-pyrazol-3-yl}-3- 1006 hydroxyphenyl) isonicotinamide N- (4- {5-cyclopentyl-1- [ (propylamino) carbonyl]-1H-pyrazol-3-yl}-3- 1007 hydroxyphenyl) isonicotinamide s N- {1-[(benzylamino) carbonyl3-5-cyclopentyl-lH-pyrazol-3-yl}-3- 1008 hydroxyphenyl) isonicotinamide N- [4- (5-cyclopentyl-l- { [ (2-phenylethyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 1009 hydroxyphenyl] isonicotinamide N-[4-(5-cyclopentyl-1- {[(2-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 1010 hydroxyphenyl] isonicotinamide N- [4- (5-cyclopentyl-1- [ (3-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 1011 hydroxyphenyl isonicotinamide N- [4- (5-cyclopentyl-l- { [ (4-methyIbenzyl) ammo] carbonyl}-lH-pyrazoI-3-yl)-3- hydroxyphenyl] isonicotinamide N- [4- (1- { [ (2-chlorobenzyl) amino] carbonyl}-5-cyclopentyl-lH-pyrazol-3-yl)-3- hydroxyphenyl] isonicotinamide N- [4- (5-cyclopentyl-l- { [ (4-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 1014 hydroxyphenyl] isonicotinamide N- [4- (5-cyclopentyl-l- { [ (3, 4-dichlorobenzyl) amino) carbonyl}-lH-pyrazol-3-yl)- 1015 3-hydroxyphenyl] isonicotinamide N- [4- (5-cyclopentyl-l-f [ (4-methoxybenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 1016 hydroxyphenyl] isonicotinamide N- {1-[(sec-butylamino) carbonyl]-5-cyclopentyl-lH-pyrazol-3-yl}-3- 1017 hydroxyphenyl) isonicotinamide N- [4- (5-cyclopentyl-l- { [ (2-fluorobenzyl) amino] carbonyl}-IH-pyrazol-3-yl)-3- 1018 hydroxyphenyl] isonicotinamide N- [4- (5-cyclopentyl-1- { [ (3-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 1019 hydroxyphenyl] isonicotinamide N- {5-cyclopentyl-1-[(cyclopropylamino) carbonyl]-lH-pyrazol-3-yl}-3- 1020 hydroxyphenyl) isonicotinamide 3- 4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- 1021 isopropyl-1 H-pyrazole-1-carboxamide 3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- 1022 ethyl-1H-yrazole-1-carboxamide N-allyl-3- {4-[(1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5- 1023 cyclopropyl-lH-pyrazole-1-carboxamide 3- {4-[(1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- 1024 propyl-lH-pyrazole-1-carboxamide 3-f 4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-N-benzyl-5- 1025 cyclopropyl-lH-pyrazole-1-carboxamide 3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- 1026 (2-henylethyl)-1H-yrazole-1-caxboxamide 3- {4- [ (l, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- 1027 (2-methylbenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- 1028 (3-methylbenzyl)-lH-pyrazole-1-carboxamide 3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- 1029 (4-methylbenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (l, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-N- (2- 1030 chlorobenzyl)-5-cyclopropyl-lH-pyrazole-l-carboxamide 3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- 1031 (4-fluorobenzyl)-lH-Dyrazole-l-carboxamide 3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- 1032 (3, 4-dichlorobenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- 1033 4-methoxybenzyl)-1H-yrazole-1-carboxamide 3- {4- [ (l, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-N-(sec-butyl)-5- 1034 cyclopropyl-lH-pyrazole-1-carboxamide 3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- 1035 (2-fluorobenzyl)-1 H-pyrazole-1-carboxamide o 3- {4- [ (1, 3-benzo dioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- 1036 (3-fluorobenzyl)-1H-pyrazole-1-carboxamide 3- {4-[(1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-N, 5- 1037 dicyclopropyl-1 H-pyrazole-1-carboxamide 3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- 1038 isopropyl-1 H-pyrazole-1-carboxamide 3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- 1039 ethyl-1 H-pyrazole-1-carboxamide N-allyl-3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5- 1040 cyclobutyl-1 H-pyrazole-1-carboxamide 3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- 1041 propyl-1 H-pyrazole-1-carboxamide 3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-N-benzyl-5- 1042 cyclobutyl-1 H-pyrazole-1-carboxamide 3- {4- [ (l, 3-benzodioxol-S-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- 1043 (2-phenylethyl)-lH-pyrazole-1-carboxamide 3- {4-[(1, 3-benzodioXol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- 1044 (2-methylbenzyl)-lH-pyrazole-l-carboxamide 3- {4-[(1, 3-benzodioXol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- 1045 (3-methylbenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino3-2-hydroxyphenyl}-5-cyclobutyl-N- 1046 (4-methylbenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-N-(2- 1047 chlorobenzyl)-5-cyclobutyl-lH-pyrazole-l-carboxamide 3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- 1048 (4-fluorobenzyl)-1H-yrazole-1-carboxamide 3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- 1049 (3, 4-dichlorobenzyl)-1 H-pyrazole-1-carboxamide 3- 4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- 1050 (4-methoxybenzyl)-lH-pyrazole-l-carboxamide 3- {4-[(1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-N-(sec-butyl)-5- 1051 cyclobutyl-1 H-pyrazole-1-carboxamide 3- {4- [ (l, 3-benzodioxol-5-ylcarbonyl) ammo]-2-hydroxyphenyl}-5-cyclobutyl-N- 1052 (2-fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- 1053 (3-fluorobenzyl)-lH-pyrazole-l-carboxamide 3-{4-[(1, 3-benzodioxol-5-ylcarbonyl) amìno] 2 hydroxyphenyl}-5-cyclobutyl-N 1054 cyclopropyl-lH-pyrazole-l-carboxamide 3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 1055 isopropyl-1 H-pyrazole-1-carboxamide 3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 1056 ethyl-1 H-pyrazole-1-carboxamide N-allyl-3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5- 1057 cyclosentyl-lH-uyrazole-l-carboxamide A A _ 3- 4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 1058 propyl-lH-pyrazole-1-carboxamide 3-f4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-N-benzyl-5- 1059 cyclo entyl-1H-yrazole-1-carboxamide A A 3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 1060 (2-phenylethyl)-1H-pyrazole-1-carboxamide A 3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) ammo]-2-hydroxyphenyl}-5-cyclopentyI-N- 1061 (2-methylbenzyl)-IH-pyrazole-l-carboxamide 3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 1062 (3-methylbenzyl)-lH-pyrazole-l-carboxamide 3- {4-[(1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 1063 (4-methylbenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (l, 3-benzodioxol-5-ylcarbonyI) ammo]-2-hydroxyphenyl}-N- (2- 1064 chlorobenzyl)-5-cyclop entyl-1 H-pyrazole-1-carboxamide 3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 1065 (4-fluorobenzyl)-1H-pyrazole-1-carboxamide 3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 1066 (3, 4-dichlorobenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl3-5-cyclopentyl-N- 1067 (4-methoxybenzyl)-lH-pyrazole-l-carboxamide 3- {4-[(1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-N-(sec-butyl)-5- 1068 cyclopentyl-lH-pyrazole-l-carboxamide 3-f4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 1069 (2-fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 1070 (3-fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (1, 3-benzodioxol-5-ylcarbonyl) arnino]-2-hydroxyphenyl}-5-cyclopentyl-N- 1071 cyclopropyl-1H-pyrazole-1-carboxamide 5-cyclopropyl-3- {4- [ (2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-isopropyl-lH- 1072 pyrazole-1-carboxamide 5-cyclopropyl-N-ethyl-3- {4-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-1H- 1073 pyrazole-l-carboxamide N-allyl-5-cyclopropyl-3- {4- [ (2-ethylbutanoyl) amino]-2-hydroxyphenyl}-lH- 1074 pyrazole-1-carboxamide 5-cyclopropyl-3- {4-f (2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-propyl-lH- 1075 pyrazole-1-carboxamide N-benzyl-5-cyclopropyl-3- {4-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-1H- 1076 pyrazole-1-carboxamide 5-cyclopropyl-3- {4-[(2-ethylbutanoyl) arnino]-2-hydroxyphenyl}-N-(2- 1077 henylethyl)-lH-pyrazole-1-carboxamide 5-cyclopropyl-3- {4-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-(2- 1078 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {4-[(2-ethylbutanoyl) asnino]-2-hydroxyphenyl}-N-(3- 1079 methylbenzyl)-1H-pyrazole-1-carboxamide 5-cyclopropyl-3- {4- [ (2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N- (4- 1080 methylbenzyl)-IH-pyrazole-l-carboxamide N-(2-chlorobenzyl)-5-cyclopropyl-3- {4-[(2-ethylbutanoyl) amino]-2- 1081 hydroxyrphenyl}-1 H-pyrazole-1-carboxamide 5-cyclopropyl-3- {4-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-(4- 1082 fluorobenzyl)-IH-pyrazole-1-carboxamide 5-cyclopropyl-N-(3, 4-dichlorobenzyl)-3- {4-[(2-ethylbutanoyl) amino]-2- 1083 hydroxyphenyl}-1 H-pyrazole-1-carboxamide 5-cyclopropyl-3- {4- [ (2-ethyIbutanoyl) ammo]-2-hydroxyphenyl}-N- (4- 1084 methoxybenzyl)-lH-pyrazole-l-carboxamide N-(sec-butyl)-5-cyclopropyl-3- {4-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}- 1085 IH-pyrazole-l-carboxamide 6 5-cyclopropyl-3- {4- [ (2-ethylbutanoyl) amino]-2-hydroxyphenyll-N- (2- 1086 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3-{4-[(2-ethylbutanoyl) arnino]-2-hydroxyphenyl}-N-(3- 1087 fluorobenzyl)-lH-pyrazole-l-carboxamide N, 5-dicyclopropyl-3- {4-[(2-ethylbutanoyl) anqino]-2-hydroxyphenyl}-1H- 1088 pyrazole-l-carboxarnide 5-cyclobutyl-3- {4-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-isopropyl-lH- 1089 pyrazole-1-carboxamide 5-cyclobutyl-N-ethyl-3- {4- [ (2-ethylbutanoyl) amino]-2-hydroxyphenyl}-lH- 1090 pyrazole-1-carboxamide N-allyl-5-cyclobutyl-3- {4-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-1H- 1091 pyrazole-l-carboxamide 5-cyclobutyl-3- {4- [ (2-ethylbutanoyl) ammo]-2-hydroxyphenyl}-N-propyl-lH- 1092 yrazole-1-carboxamide N-benzyl-5-cyclobutyl-3- {4- [ (2-ethylbutanoyl) amino]-2-hydroxyphenyl}-lH- 1093 yrazole-1-caxboxamide' 5-cyclobutyl-3- {4-[(2-ethylbutaMoyl) amino]-2-hydroxyphenyl}-N-(2-phenylethyl)- 1094 1094 1H-pyrazole-l-carboxamide 5-cyclobutyl-3- {4- [ (2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N- (2- 1095 methylbenzyl)-IH-pyrazole-1-carboxamide 5-cyclobutyl-3- {4- [ (2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N- (3- 1096 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {4-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-(4- 1097 methylbenzyl)-lH-pyrazole-1-carboxamide N-(2-chlorobenzyl)-5-cyclobutyl-3- {4-[(2-ethylbutanoyl) amino]-2- 1098 hydroxyphenyl}-lH-pyrazole-l-carboxamide _ _ 5-cyclobutyl-3- {4-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-(4- 1099 fluorobenzyl)-1 H-pyrazole-1-carboxamide 5-cyclobutyl-N- (3, 4-dichlorobenzyl)-3-4- [ (2-ethylbutanoyl) amino]-2- 1100 hydroxyphenyl}-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {4-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-(4- 1101 methoxybenzyl)-lH-pyrazole-l-carboxamide N-(sec-butyl)-5-cyclobutyl-3- {4-[(2-ethylbutanoyl) arnino]-2-hydroxyphenyl}-1H- 1102 pyrazole-1-carboxamide 5-cyclobutyl-3- {4-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-(2- 1103 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {4-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-(3- 1104 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-N-cyclopropyl-3- {4-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}- 1105 IH-pyrazole-1-carboxamide A 5-cyclopentyl-3- {4-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-isopropyl-lH- 1106 pyrazole-1-carboxamide 5-cyclopentyl-N-ethyl-3- {4- [ (2-ethylbutanoyl) amino]-2-hydroxyphenyl}-lH- 1107 pyrazole-l-carboxamide A N-allyl-5-cyclopentyl-3- {4-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-1H- 1108 pyrazole-1-carboxamide 5-cyclopentyl-3- {4-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-propyl-lH- 1109 pyrazole-1-carboxamide N-benzyl-5-cyclopentyl-3- {4-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-1H- 1110 pyrazole-1-carboxamide 5-cyclopentyl-3- {4-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-(2- 1111 |-shenylethyl)-H-pyrazole-l-carboxamide 5-cyclopentyl-3- {4-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-(2- 1112 methylb enzyl)-1 H-pyrazole-1-carboxamide 5-cyclopentyl-3- {4- [ (2-ethyIbutanoyl) amino]-2-hydroxyphenyl}-N- (3- 1113 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {4- [ (2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N- (4- 1114 methylbenzyl)-l H-pyrazole-1-carboxamide N-(2-chlorobenzyl)-5-cyclopentyl-3- {4-[(2-ethylbutanoyl) amino]-2- 1115 hydroxyphenyl}-1H-pyrazole-1-carboxamide 5-cyclopentyl-3- {4-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-(4- 1116 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-N- (3, 4-dichlorobenzyl)-3- {4- [ (2-ethylbutanoyl) amino)-2- 1117 hydroxyphenyl-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {4- [ (2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N- (4- 1118 methoxybenzyl)-lH-pyrazole-l-carboxamide N-(sec-butyl)-5-cyclopentyl-3- {4-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}- 1119 1 H-pyrazole-1-carboxamide 5-cyclopentyl-3- {4-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-(2- 1120 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3-f 4- [ (2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N- (3- 1121 fluorobenzyl)-1H-pyrazole-l-carboxamide 5-cyclopentyl-N-cyclopropyl-3- {4- [ (2-ethylbutanoyl) ammo]-2-hydroxyphcnyl}- 1122 IH-pyrazole-l-carboxamide 3- {4-[(1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- 1123 isopropyl-lH-pyrazole-l-carboxamide 3- {4- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- 1124 ethyl-1H-pyrazole-1-carboxamide N-allyl-3- {4- [ (I-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-S- 1125 cyclopropyl-lH-pyrazole-l-carboxamide 3- {4-[(1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- 1126 ropyl-lH-pyrazole-l-carboxamide 3- {4- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-N-benzyl-5- 1127 cyclopropyl-1 H-pyrazole-1-carboxamide 3- {4-[(1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N-(2- 1128 phenylethyl)-lH-pyrazole-l-carboxamide 3- {4- [ (l-benzothien-2-ylcarbonyl) ammo]-2-hydroxyphenyl}-5-cyclopropyl-N- (2- 1129 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {4-[(1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N-(3- 1130 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (4- 1131 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {4-[(1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-N-(2-chlorobenzyl)- 1132 5-cyclopropyl-1H-pyrazole-1-carboxamide 3- 4- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (4- 1133 fluorobenzyl)-1H-yrazole-1-carboxamide 3- {4- [ (1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- 1134 (3, 4-dichlorobenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (4- 1135 methoxybenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-N- (sec-butyl)-5- 113 6 cyclopropyl-l H-pyrazole-1-carboxamide 3-f4- [ (I-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (2- 1137 fluorobenzyl)-lH-pyrazole-l-carboxamide 3-4- [ ( 1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-S-cyclopropyl-N- (3- 1138 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- 4- [ (1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-N, 5-dicyclopropyl- 1139 1H-pyrazole-l-carboxamide 3- {4- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- 1140 isopropyl-1 H-pyrazole-1-carboxamide 3- {4-[(1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- 1141 ethyl-1H-yrazole-1-carboxamide N-allyl-3-{4-[(1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl- 1142 1 H-pyrazole-1-carboxamide 3- {4- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- 1143 propyl-1 H-yrazole-1-carboxamide 3- {4-[(1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-N-benzyl-5- 1144 cyclobutyl-lH-pyrazole-l-carboxamide 3- {4- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (2- 1145 phenylethyl)-lH-pyrazole-l-carboxamide 3- {4-[(1-benzothien-2-ylcarbonyl) aminoJ-2-hydroxyphenyl}-5-cyclobutyl-N-(2- 1146 methylbenzyl)-lH-pyrazole-1-carboxarnide 3- {4- [(1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-(3- 1147 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (4- 1148 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {4-[(1-benzoiien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-N-(2-chlorobenzyl)- 1149 5-cyclobutyl-lH-pyrazole-l-carboxamide 3- {4-[(1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-(4- 1 150 fluorobenzyl)-lH-pyrazole-1-carboxamide 3- {4-[(1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-(3, 4- 1151 dichlorobenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (4- 1152 methoxybenzyl)-lH-pyrazole-l-carboxarnide 3- {4-[(l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-(2- 1153 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (2- 1154 fluorobenzyl)-lH-pyrazole-1-carboxamide 3- {4-[(l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-(3- 1155 fluorobenzyl)-IH-pyrazole-1-carboxamide 3- 4- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- 1156 cycloDropyl-lH-pyrazole-l-carboxamide 3- {4-[(1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 1157 isopropyl-lH-pyrazole-l-carboxamide 3- 4- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 1158 ethyl-lH-pyrazole-1-carboxarnide N-allyl-3- {4-[(1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5- 1159 cyclopentyl-lH-pyrazole-l-carboxamide 3- {4- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 1160 propyl-lH-pyrazole-l-carboxamide 3- 4- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-N-benzyl-5- 1161 cyclopentyl-IH-pyrazole-1-carboxamide 3- 4- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (2- 1162 phenylethyl)-lH-pyrazole-l-carboxamide 3- 4- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (2- 1163 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {4-[(1-benzothien-2-ylcarbonyl) amino3-2-hydroxyphenyl}-5-cyclopentyl-N-(3- 1164 methylbenzyl)-lH-pyrazole-1-carboxamide 3- {4- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (4- 1165 methylbenzyl)-lH-pyrazole-1-carboxamide 3- {4- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-N- (2-chlorobenzyl)- 1166 5-cyclopentyl-lH-pyrazole-1-carboxamide 3- {4-[(1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-(4- 1167 fluorobenz-lH-pyrazole-l-carboxamide 3- {4- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 1168 (3, 4-dichlorobenzyl)-lH-pyrazole-l-carboxamide 3- {4- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (4- 1169 methoxybenzyl)-lH-pyrazole-l-carboxamide 3- {4- [(1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-N-(sec-butyl)-5- 1170 cyclopentyl-lH-pyrazole-l-carboxamide 3- {4- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (2- 1171 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {4-[(l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-(3- 1172 fluorobenzyl)-IH-pyrazole-1-carboxamide 3- {4- [ (1-benzothi en-2-ylcarb onyl) amino]-2-hydroxyphenyl}-5-cyclop entyl-N- 1173 cyclopropyl-lH-pyrazole-1-carboxamide 2-chloro-N-(4- {5-cyclopropyl-1-[(isopropylamino) carbonyl]-lH-pyrazol-3-yl}-3- 1174 hydroxyphenyl) nicotinamide 2-chloro-N-(4- {5-cyclopropyl-1-[(ethylamino) carbonyl]-lH-pyrazol-3-yl}-3- 1175 hydroxyphenyl) nicotinamide N- (4- {1- [ (allylamino) carbonyl]-5-cyclopropyl-lH-pyrazol-3-yl}-3- 1176 hydroxyphenyl)-2-chloronicotinamide 2-chloro-N- {5-cyclopropyl-1-[(propylamino) carbonyl]-lH-pyrazol-3-yl}-3- 1177 hydroxyphenyl) nicotinamide N- {l-[(benzylamino) carbonyl]-5-cyclopropyl-lH-pyrazol-3-yl}-3- 1178 hydroxyphenyl)-2-chloronicotinamide 2-chloro-N- [4- (5-cyclopropyl-l- { [ (2-phenylethyl) amino] carbonyl}-lH-pyrazol-3- 1179 yl)-3-hydroxyphenyl] nicotinamide 2-chloro-N- [4- (5-cyclopropyl-1- f [ (2-methylbenzyl) amino] carbonyl}-lH-pyrazol- 1180 3-yl)-3-hydroxyphenyl] nicotinamide 2-chloro-N- [4- (5-cyclopropyl-l- { [ (3-methylbenzyl) ammo] carbonyl}-lH-pyrazol- 1181 3-yl)-3-hydroxyphenyl] nicotinamide s 2-chloro-N- [4- (5-cyclopropyl-1- [ (4-methylbenzyl) amino] carbonyl}-lH-pyrazol- 1182 3-yl)-3-hydrox henyl nicotinamide 2-chloro-N- [4- (l- { [ (2-chlorobenzyl) ammo] carbonyl}-5-cyclopropyl-lH-pyrazol- 1183 3-yl)-3-hydroxyphenyl] nicotinamide 2-chloro-N- [4- (5-cyclopropyl-1- {[ (4-fluorobenzyl) amino] carbonyl}-1H-pyrazol- 1184 3-yl)-3-hydroxyphenyl] nicotinamide 2-chloro-N- [4- (5-cyclopropyl-l- { [ (3, 4-dichlorobenzyl) amino] carbonyl}-lH- 1185 pyrazol-3-yl)-3-hydroxyphenyl] nicotinamide 2-chloro-N-[4-(5-cyclopropyl-1- {[(4-methoxybenzyl) amino] carbonyl}-1H- 1186 pyrazol-3-yl)-3-hydroxyphenyl] nicotinamide N- (4- {I- [ (see-butylamino) carbonyl]-5-cyclopropyl-lH-pyrazol-3-yl)-3- 1187 hydroxyphenyl)-2-chloronicotinamide 2-chloro-N- [4- (5-cyclopropyl-1- { [ (2-fluorobenzyl) amino] carbonyl}-1H-pyrazol- 1188 3-yl)-3-hydroxyphenyl] nicotinamide 2-chloro-N- [4- (5-cyclopropyl-1- {[ (3-fluorobenzyl) amino] carbonyl}-lH-pyrazol- 1189 3-yl)-3-hydroxyphenyl] nicotinamide 2-chloro-N- {5-cyclopropyl-1-[(cyclopropylamino) carbonyl]-lH-pyrazol-3-yl}- 1190 3-hydroxyphenyl) nicotinamide 2-chloro-N-(4- {5-cyclobutyl-1-[(isopropylamino) carbonyl]-lH-pyrazol-3-yl}-3- 1191 hydroxyphenyl) nicotinamide 2-chloro-N-(4- {5-cyclobutyl-1-[(ethylaxnino) carbonyl]-lH-pyrazol-3-yl}-3- 1192 hydroxyphenyl) nicotinamide N-(4- {1-[(allylamino) carbonyl]-5-cyclobutyl-1 H-pyrazol-3-yl}-3-hydroxyphenyl)- 1193 2-chloronicotinamide 2-chloro-N-(4- {5-cyclobutyl-1-[(propylamino) carbonyl]-lH-pyrazol-3-yl}-3- 1194 hydroxyphenyl) nicotinamide N- {1-[(benzylamino) carbonyl]-5-cyclobutyl-lH-pyrazol-3-yl}-3- 1195 hydroxyphenyl)-2-chloronicotinamide 2-chloro-N- [4- (5-cyclobutyl-l- { [ (2-phenylethyl) amino] carbonyl}-lH-pyrazol-3- 1196 yl)-3-hydroxyphenyl] nicotinamide 2-chloro-N- [4-(5-cyclobutyl-1- { [(2-methylbenzyl) amino] carbonyl}-1 H-pyrazol-3- 1197 yl)-3-hydroxyphenyl] nicotinamide 2-chloro-N- [4- (5-cyclobutyl-1- [ (3-methylbenzyl) amino] carbonyl}-1H-pyrazol-3- 1198 yl)-3-hydroxyphenyl nicotinarnide 2-chloro-N-[4-(5-cyclobutyl-1- {[(4-methylbenzyl) amino] carbonyl}-lH-pyrazol-3- 1199 yl)-3-hydroxyphenyl] nicotinamide 2-chloro-N-[4-(1- {[(2-chlorobenzyl) amino] carbonyl}-5-cyclobutyl-lH-pyrazol-3- 1200 yl)-3-hydroxyphenyl] nicotinamide 2-chloro-N- [4- (5-cyclobutyl-1-1 [ (4-fluorobenzyI) amino] carbonyl)-lH-pyrazol-3- 1201 yl)-3-hydroxyphenyl] nicotinamide 2-chloro-N- [4- (5-cyclobutyl-1- f [ (3, 4-dichlorobenzyl) amino] carbonyl}-1H- 1202 pyrazol-3-yl)-3-hydroxyphenyl nicotinamide 2-chloro-N- [4- (5-cyclobutyl-l- { [ (4-methoxybenzyl) amino] carbonyl}-lH-pyrazol- 1203 3-yl)-3-hydroxyphenyl] nicotinamide N- {1-[(sec-butylamino) carbonyl]-5-cyclobutyl-lH-pyrazol-3-yl}-3- 1204 hydroxyphenyl)-2-chloronicotinamide 2-chloro-N- [4- (5-cyclobutyl-1- { [ (2-fluorob enzyl) axnino] carbonyl}-1 H-pyrazol-3- 1205 yl)-3-hydroxyphenyl] nicotinamide 2-chloro-N- [4- (5-cyclobutyl-l- { [ (3-fluorobenzyl) ammo] carbonyl}-lH-pyrazol-3- yl)-3-hydroxyphenyl] nicotinamide z 2-chloro-N-(4- {5-cyclobutyl-1-[(cyclopropylamino) carbonyl]-lH-pyrazol-3-yl}-3- 1207 hydroxyphenyl) nicotinamide 2-chloro-N-(4- {5-cyclopentyl-1-[(isopropylamino) carbonyl]-lH-pyrazol-3-yl}-3- 1208 hydroxyphenyl) nicotinamide 2-chloro-N-(4- {5-cyclopentyl-l-[(ethylamino) carbonyl]-lH-pyrazol-3-yl}-3- 1209 hydroxyphenyl) nicotinamide N- {1-[(allylamino) carbonyl]-5-cyclopentyl-lH-pyrazol-3-yl}-3- 1210 hydroxyphenyl)-2-chloronicotinamide 2-chloro-N- {5-cyclopentyl-1-[(propylamino) carbonyl]-lH-pyrazol-3-yl}-3- 1211 hydroxyphenyl) nicotinamide N- {1-[(benzylamino) carbonyl]-5-cyclopentyl-lH-pyrazol-3-yl}-3- 1212 hydroxyphenyl)-2-chloronicotinarnide 2-chloro-N- [4- (5-cyclopentyl-l- { [ (2-phenylethyl) ammo] carbonyl}-lH-pyrazol-3- 1213 yl)-3-hydroxyphenyl] nicotinamide 2-chloro-N- [4- (5-cyclopentyl-1- {[ (2-methylbenzyl) arnino] carbonyl}-lH-pyrazol- 1214 3-yl)-3-hydroxyphenyl] nicotinamide 2-chloro-N- [4- (5-cyclopentyl-1- [ (3-methylbenzyl) amino] carbonyl}-lH-pyrazol- 1215 3-yl)-3-hydroxyphenyl] nicotinamide 2-chloro-N- [4- (5-cyclopentyl-1- {[ (4-methylbenzyl) axnino] carbonyl}-IH-pyrazol- 1216 3-yl)-3-hydroxyphenyl] nicotinamide 2-chloro-N- [4- (l- { [ (2-chlorobenzyl) ammo] carbonyl}-5-cyclopentyl-IH-pyrazol- 1217 3-yl)-3-hydroxyphenyl] nicotinamide 2-chloro-N- [4- (5-cyclopentyl-1- [ (4-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3- 1218 yl)-3-hydroxyphenyl nicotinamide 2-chloro-N- [4- (5-cyclopentyl-l- { [ (3, 4-dichlorobenzyl) amino] carbonyl}-1H- 1219 pyrazol-3-yl)-3-hydroxyphenyl] nicotinamide 2-chloro-N- [4- (5-cyclopentyl-1- [ (4-methoxybenzyl) amino] carbonyl}-lH- 1220 pyrazol-3-yl)-3-hydroxyphenyl] nicotinamide N- {1-[(sec-butylasnino) carbonyl]-5-cyclopentyl-1 H-pyrazol-3-yl}-3- 1221 hydroxyphenyl)-2-chloronicotinamide 2-chloro-N- [4- (5-cyclopentyl-1- f [ (2-fluorobenzyl) aminoJcarbonyl}-1H-pyrazol-3- 1222 yl)-3-hydrox henyl nicotinamide 2-chloro-N-[4-(5-cyclopentyI-1- {[(3-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3- 1223 yl)-3-hydroxyphenyl] nicotinamide 2-chloro-N- {5-cyclopentyl-1-[(cyclopropylamino) carbonyl]-lH-pyrazol-3-yl}- 1224 3-hydroxyphenyl) nicotinamide 5-cyclopropyl-3-(2-hydroxy-4- {[4-(trifluoromethoxy) benzoyl] amino} phenyl)-N- 1225 isopropyl-lH-pyrazole-l-carboxamide 5-cyclopropyl-N-ethyl-3-(2-hydroxy-4- {[4- 1226 (trifluoromethoxy) benzoyl] amino} phenyl)-1 H-pyrazole-1-carboxamide N-allyl-5-cyclopropyl-3- (2-hydroxy-4- { [4- 1227 (trifluoromethoxy) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3-(2-hydroxy-4- {[4-(trifluoromethoxy) benzoyl] amino} phenyl)-N- 1228 propyl-lH-pyrazole-l-carboxamide N-benzyl-5-cyclopropyl-3- (2-hydroxy-4- { [4- 1229 (trifluoromethoxy) benzoyl amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- (2-hydroxy-4- { [4- (trifluoromethoxy) benzoyl] amino} phenyl)-N- 1230 (2-phenylethyl)-1 H-pyrazole-1-carboxamide 5-cyclopropyl-3-(2-hydroxy-4- {[4-(trifluoromethoxy) benzoyl] amino} phenyl)-N- 1231 (2-methylbenzyl)-lH-pyrazole-1-carboxamide A 5-cyclopropyl-3- (2-hydroxy-4- {[4- (trifluoromethoxy) benzoyl] amino} phenyl)-N- 1232 (3-methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3-(2-hydroxy-4- {[4-(trifluoromethoxy) benzoyl] amino} phenyl)-N- 1233 (4-methylbenzyl)-lH-pyrazole-l-carboxamide N-(2-chlorobenzyl)-5-cyclopropyl-3-(2-hydroxy-4- { [4- 1234 (trifluoromethoxy) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-N- (4-fluorobenzyl)-3- (2-hydroxy-4- { [4- 1235 (trifluoromethoxy) benzoyl] amino} phenyl)-1H-pyrazole-1-carboxamide 5-cyclopropyl-N- (3, 4-dichlorobenzyl)-3- (2-hydroxy-4- { [4- 1236 (trifluoromethoxy) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3-(2-hydroxy-4- {[4-(trifluoromethoxy) benzoyl] amino} phenyl)-N- 1237 (4-methoxybenzyl)-lH-pyrazole-l-carboxamide N-(sec-butyl)-5-cyclopropyl-3-(2-hydroxy-4- { [4- 1238 (trifluoromethoxy) benzoyl] amino} phenyl)-1 H-pyrazole-1-carboxamide 5-cyclopropyl-N- (2-fluorobenzyl)-3- (2-hydroxy-4- { [4- 1239 (trifluoromethoxy) benzoyl] amino} phenyl)-1H-pyrazole-1-carboxamide 5-cyclopropyl-N-(3-fluorobenzyl)-3-(2-hydroxy-4- { [4- 1240 (trifluoromethoxy) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide N, 5-dicyclopropyl-3-(2-hydroxy-4- {[4-(trifluoromethoxy) benzoyl] amino} phenyl)- 1241 lH-pyrazole-l-carboxamide 5-cyclobutyl-N-ethyl-3- (2-hydroxy-4- { [4- 1242 (trifluoromethoxy) benzoyl] amino} phenyl)-1 H-pyrazole-1-carboxamide 5-cyclobutyl-N-ethyl-3-(2-hydroxy-4- { [4- 1243 (trifluoromethoxy) benzoyl] amino henyl)-lH-pyrazole-l-carboxamide N-allyl-5-cyclobutyl-3- (2-hydroxy-4- { [4- 1244 (trifluoromethoxy) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3-(2-hydroxy-4- {[4-(trifluoromethoxy) benzoyl3aminophenyl)-N- 1245 propyl-lH-pyrazole-1-carboxamide N-benzyl-5-cyclobutyl-3- (2-hdroxy-4- [4- 1246 (trifluoromethoxy) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3-(2-hydroxy-4- {[4-(trifluoromethoxy) benzoyl] amino} phenyl)-N- (2- 1247 phenylethyl)-lH-pyrazole-l-carboxarnide 5-cyclobutyl-3-(2-hydroxy-4- {[4-(trifluoromethoxy) benzoyl3amino} phenyl)-N-(2- 1248 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3-(2-hydroxy-4- {[4-(trifluoromethoxy) benzoyi] amino} phenyl)-N-(3- 1249 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3-(2-hydroxy-4- {[4-(trifluoromethoxy) benzoyl] amino} phenyl)-N-(4- 1250 methylbenzyl)-lH-yrazole-l-carboxamide A N- (2-chlorobenzyl)-5-cyclobutyl-3- (2-hydroxy-4- { [4- 1251 (trifluoromethoxy) benzoyl] arnino} phenyl)-lH-pyrazole-1-carboxamide 5-cyclobutyl-N- (4-fluorobenzyl)-3- (2-hydroxy-4- f [4- 1252 (trifluoromethoxy) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-N- (3, 4-dichlorobenzyl)-3- (2-hydroxy-4- { [4- 1253 (trifluoromethoxy) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3-(2-hydroxy-4- {[4-(trifluoromethoxy) benzoyl] amino} phenyl)-N- (4- 1254 methoxybenzyl)-lH-pyrazole-l-carboxamide N- (sec-butyl)-5-cyclobutyl-3- (2-hydroxy-4-f [4-. 1255 (trifluoromethoxy) benzoyl] amino} henyl)-lH-Dyrazole-l-carboxamide A A 5-cyclobutyl-N-(2-fluorobenzyl)-3-(2-hydroxy-4- {[4- 1256 (trifluoromethoxy) benzoyl] amino} phenyl)-IH-pyrazole-1-carboxamide S 5-cyclobutyl-N- (3-fluorobenzyl)-3- (2-hydroxy-4- { [4- 1257 (trifluoromethoxy) benzoyl] amino} phenyl)-lH-pyrazole-1-carboxamide 1257 N-allyl-5-cyclopentyl-3-(2-hydroxy-4- {[4- 1258 (trifluoromethoxy) benzoYllamino} shenyl)-lH-nyrazole-l-carboxamide w P A 5-cyclopentyl-3-(2-hydroxy-4- {[4-(trifluoromethoxy) benzoyl] amino} phenyl)-N- 1259 isopropyl-lH-pyrazole-1-carboxamide 5-cyclopentyl-N-ethyl-3- (2-hydroxy-4- f [4- 1260 (trifluoromethoxy) benzoyllamino} phenyl)-lH-pyrazole-l-carboxarnide 0 N-allyl-5-cyclopentyl-3-(2-hydroxy-4- { [4- 1261 (trifluoromethoxy) benzoyl] amino henyl)-lH-pyrazole-1-carboxamide 5-cyclopentyl-3-(2-hydroxy-4- {[4-(trifluoromethoxy) benzoyl] amino} phenyl)-N- 1262 ro yl-1H-yrazole-1-carboxamide N-benzyl-5-cyclopentyl-3-(2-hydroxy-4- {[4- 1263 (trifluoromethoxy) benzoyl] amino} phenyl)-1H-pyrazole-1-carboxamide 5-cyclopentyl-3-(2-hydroxy-4- {[4-(trifluoromethoxy) benzoyl] amino} phenyl)-N- 1264 (2-phenylethyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3-(2-hydroxy-4- {[4-(trifluoromethoxy) benzoyl] amino} phenyl)-N- 1265 (2-methylbenzyl)-lH-pyrazole-l-carboxatnide 5-cyclopentyl-3-(2-hydroxy-4- {[4-(trifluoromethoxy) benzoyl] amino} phenyl)-N- 1266 (3-methylbenzyl)-lH-pyrazole-1-carboxamide 5-cyclopentyl-3-(2-hydroxy-4- {[4-(trifluoromethoxy) benzoyl3amino} phenyl)-N- 1267 (4-methylbenzyl)-1H-yrazole-1-carboxamide N-(2-chlorobenzyl)-5-cyclopentyl-3-(2-hydroxy-4- {[4- 1268 (trifluoromethoxy) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-N-(4-fluorober zyl)-3-(2-hydroxy-4- { [4- 1269 (trifluoromethoxy) benzoyl] amino henyl)-1H-pyrazole-1-carboxamide 5-cyclopentyl-N- (3, 4-dichlorobenzyl)-3- (2-hydroxy-4- f [4- 1270 (tifluoromethoxymbenzoylJamino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3-(2-hydroxy-4- {[4-(trifluoromethoxy) benzoyl] arnino} phenyl)-N- 1271 (4-methoxybenzyl)-1 H-pyrazole-1-carboxamide N- (s ec-butyl)-5-cyclopentyl-3- (2-hydroxy-4- { (4- 1272 (trifluoromethoxy) benzoyllaminoWphenyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-N-(2-fluorobenzyl)-3-(2-hydroxy-4- {[4- 1273 (trifluoromethoxy) benzoyl] amino} phenyl)-1H-pyrazole-1-carboxamide 5-cyclopentyl-N- (3-fluorobenzyl)-3- (2-hydroxy-4- { [4- 1274 (trifluoromethoxy) benzoyl] amino henyl)-1H-pyrazole-1-carboxamide 5-cyclopentyl-N-cyclopropyl-3- (2-hydroxy-4- { [4- 1275 (trifluoromethoxy) benzoyl] amino} phenyl)-1H-pyrazole-1-carboxamide A N-(4- {5-cyclopropyl-1-[(isopropylamino) carbonyl]-lH-pyrazol-3-yl3-3- 1276 hydroxyphenyl) isoxazole-5-carboxamide N-(4- {5-cyclopropyl-1-[(ethylamino) carbonyl]-lH-pyrazol-3-yl}-3- 1277 hydroxyphenyl) isoxazole-5-carboxamide A N-(4- {1-[(allylamino) carbonyl]-5-cyclopropyl-lH-pyrazol-3-yl}-3- 1278 hydroxyphenyl) isoxazole-5-carboxamide A N- (4- {5-cyclopropyl-1- [ (propylamino) carbonyl]-lH-pyrazol-3-yl}-3- 1279 hydroxyphenyl) isoxazole-5-carboxamide N- (4- {1- [ (benzylamino) carbonyl]-5-cyclopropyl-1 H-pyrazol-3-yl}-3- hydroxyphenyl) isoxazole-5-carboxamide A N- [4- (5-cyclopropyl-1- {[ (2-phenylethyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 1281 hydroxyphenyl] isoxazole-5-carboxamide N- [4- (5-cyclopropyl-1- f [ (2-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 1282 hydroxyphenyl] isoxazole-5-carboxamide N- [4- (5-cyclopropyl-1- f [ (3-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 1283 hydroxyDhenyl] isoxazole-5-carboxamide N- [4- (5-cyclopropyl-l- { [ (4-methylbenzyl) aminojcarbonyll-IH-pyrazol-3-yl)-3- 1284 hydroxyphenyl] isoxazole-5-carboxamide N- [4- (l- { [ (2-chlorobenzyl) arnino] carbonyl}-5-cyclopropyl-lH-pyrazol-3-yl)-3- 1285 hydroxyphenyl] isoxazole-5-carboxamide N- [4-(5-cyclopropyl-1- {[(4-fluorobenzyl) amino] carbonyl}-1 H-pyrazol-3-yl)-3- 1286 hydroxyphenyl] isoxazole-5-carboxamide N- [4- (5-cyclopropyl-1- f [ (3, 4-dichlorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)- 1287 3-hydroxyphenyl] isoxazole-5-carboxamide N- [4- (5-cyclopropyl-l- { [ (4-methoxybenzyl) ammo] carbonyl}-lH-pyrazol-3-yl)-3- 1288 hydroxyphenyl] isoxazole-5-carboxamide N-(4- {1-[(sec-butylamino) carbonyl]-5-cyclopropyl-lH-pyrazol-3-yl}-3- 1289 hydroxyphenyl) isoxazole-5-carboxamide N- [4- (5-cyclopropyl-1- { [ (2-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 1290 hydroxyphenyl] isoxazole-5-carboxamide N-[4-(5-cyclopropyl-1- {[(3-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 1291 hydroxyphenyl] isoxazole-5-carboxamide N-(4- {5-cyclopropyl-1-[(cyclopropylamino) carbonyl]-lH-pyrazol-3-yl}-3- 1292 hydroxyphenyl) isoxazole-5-carboxamide N- (4- f 5-cyclobutyl-1- [ (isopropylamino) carbonyl]-lH-pyrazol-3-yl}-3- 1293 hydroxyphenyl) isoxazole-5-carboxamide N- {5-cyclobutyl-1-[(ethylamino) carbonylJ-lH-pyrazol-3-yl}-3- 1294 hydroxyphenyl) isoxazole-5-carboxamide N- (4- 1- [ (allylamino) carbonyl]-5-cyclobutyl-lH-pyrazol-3-yl}-3- 1295 hydroxyphenyl) isoxazole-5-carboxamide N- {5-cyclobutyl-1-[(propylamino) carbonyl]-lH-pyrazol-3-yl}-3- 1296 hydroxyphenyl) isoxazole-5-carboxamide N- (4- 1- [ (benzylamino) carbonyl]-5-cyclobutyl-lH-pyrazol-3-yl}-3- 1297 hydroxyphenyl) isoxazole-5-carboxamide N- [4- (5-cyclobutyl-1- { [ (2-phenylethyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 1298 hydroxyphenyl] isoxazole-5-carboxamide N- [4- (5-cyclobutyl-1- { [ (2-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 1299 hydroxyphenyl] isoxazole-5-carboxamide N- [4- (5-cyclobutyl-1- { [ (3-methylbenzyl) arnino] carbonyl-1 H-pyrazol-3-yl)-3- 1300 hydroxyphenyl] isoxazole-5-carboxamide N- [4- (5-cyclobutyl-l- { [ (4-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 1301 hydroxyphenyl] isoxazole-5-carboxamide N- [4- (1- [ (2-chlorobenzyl) amino] carbonyl}-5-cyclobutyl-IH-pyrazol-3-yl)-3- 1302 hydroxyphenyl] isoxazole-5-carboxamide N- [4- (5-cyclobutyl-1- f [ (4-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 1303 hydroxyphenyl] isoxazole-5-carboxamide N- [4- (5-cyclobutyl-l- { [ (3, 4-dichlorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 1304 hydroxyphenyl] isoxazole-5-carboxamide N- [4- (5-cyclobutyl-l- { [ (4-methoxybenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 1305 hydroxyphenyl] isoxazole-5-carboxamide N- (4- { 1- [ (sec-butylamino) carbonyl]-5-cyclobutyl-lH-pyrazol-3-yl}-3- 1306 hydroxyphenyl) isoxazole-5-carboxamide N- [4- (5-cyclobutyl-1- [ (2-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 1307 hydroxyphenyl] isoxazole-5-carboxamide N- [4- (5-cyclobutyl-l- { [ (3-iluorobenzyl) ainino] carbonyl}-lH-pyrazol-3-yl)-3- 1308 hydroxyphenyl] isoxazole-5-carboxamide N- {5-cyclobutyl-1-[(cyclopropylamino) carbonyl]-lH-pyrazol-3-yl}-3- 1309 hydroxyphenyl) isoxazole-5-carboxamide N- (4- 5-cyclopentyl-1- [ (isopropylamino) carbonyl]-lH-pyrazol-3-yl}-3- 1310 hydroxyphenyl) isoxazole-5-carboxamide N-(4- {5-cyclopentyl-1-[(ethylamino) carbonyl]-lH-pyrazol-3-yl}-3- 1311 hydroxyphenyl) isoxazole-5-carboxamide N- {1-[(allylamino) carbonyl]-5-cyclopentyl-lH-pyrazol-3-yl}-3- 1312 hydroxyphenyl) isoxazole-5-carboxamide N-(4- {5-cyclopentyl-1-[(propylamino) carbonyl]-lH-pyrazol-3-yl}-3- 1313 hydroxyphenyl) isoxazole-5-carboxamide N-(4- {1-E (benzylamino) carbonyl]-5-cyciopentyl-1H-pyrazol-3-yl}-3- 1314 hydroxyphenyl) isoxazole-5-carboxamide N- [4- (5-cyclopentyl-1- { [ (2-phenylethyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 1315 hydroxyphenyl] isoxazole-5-carboxamide N- [4- (5-cyclopentyl-1-1 [ (2-methylbenzyl) amino] carbonyl}-IH-pyrazol-3-yl)-3- l 316 hydroxyphenyl] isoxazole-5-carboxamide N- [4- (5-cyclopentyl-1- [ (3-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 1317 hydroxyphenyl] isoxazole-5-carboxamide N- [4- (5-cyclopentyl-1-1 [ (4-methylbenzyl) amino] ca, rbonyll-lH-pyrazol-3-yl)-3- 1318 hydroxyphenyl] isoxazole-5-carboxarnide - [4- (l- { [ (2-chlorobenzyl) amino] carbonyl}-5-cyclopentyl-lH-pyrazol-3-yl)-3- 1319 hydroxyphenyl] isoxazole-5-carboxamide N- [4- (5-cyclopcntyl-l- { [ (4-iluorobenzyl) ammo] carbonyl}-lH-pyrazol-3-yl)-3- 1320 hydrox henyllisoxazole-5-carboxamide N- [4- (5-cyclopentyl-l- { [ (3, 4-dichlorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)- 1321 3-hydroxyphenyl isoxazole-5-carboxamide A 9 N-j4- (5-cyclopentyl-1- { [ (4-methoxybenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 1322 hydroxyphenyl] isoxazole-5-carboxamide N-(4- {1-[(sec-butylamino) carbonyl]-5-cyclopentyl-lH-pyrazol-3-yl}-3- 1323 hydroxyphenyl) isoxazole-5-carboxamide N- [4- (5-cyclopentyl-1- f [ (2-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 1324 hydroxyphenyl] isoxazole-5-carboxamide N- [4- (5-cyclopentyl-l- { [ (3-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-3- 1325 hydroxyphenyl] isoxazole-5-carboxamide N-(4- {5-cyclopentyl-1-[(cyclopropylamino) carbonyl]-lH-pyrazol-3-yl}-3- 1326 hydroxyphenyl) isoxazole-5-carboxamide 5-cyclopropyl-3- (2-hydroxy-4- [ (1-methyl-lH-pyrrol-2- 1327 yl) carbonyl amino phenyl)-N-isopropyl-IH-pyrazole-I-carboxamide 5-cyclopropyl-N-ethyl-3-(2-hydroxy-4- {[(1-methyl-lH-pyrrol-2- 1328 yl) carbonyl] amino} phenyl)-1H-pyrazole-1-carboxamide N-allyl-5-cyclopropyl-3-(2-hydroxy-4- {[(1-methyl-lH-pyrrol-2- 1329 yl) carbonyl] amino phenyl)-1H-pyrazole-1-carboxamide 5-cyclopropyl-3- (2-hydroxy-4- {[ (1-methyl-IH-pyrrol-2- 1330 yl) carbonyl] amino}phenyl)-N-propyl-lH-pyrazole-1-carboxamide N-benzyl-5-cyclopropyl-3-(2-hydroxy-4- {[(1-methyl-lH-pyrrol-2- 1331 yl) carbonyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3-(2-hydroxy-4- {[(1-methyl-lH-pyrrol-2- 1332 yl) carbonyl] amino} phenyl)-N- (2-phenylethyl)- IH-pyrazole-1-carboxamide 5-cyclopropyl-3-(2-hydroxy-4- {[(1-methyl-lH-pyrrol-2- 1333 yl) carbonyl] amino henyl)-N- (2-methylbenzyl)-lH-pyrazole-1-carboxamide 5-cyclopropyl-3-(2-hydroxy-4- {[(1-methyl-lH-pyrrol-2- 1334 yl) carbonyl) amino} phenyl)-N- (3-methylbenzyl)-lH-pyrazole-l-carboxamide v v 5-cyclopropyl-3-(2-hydroxy-4- {[(1-methyl-lH-pyrrol-2- 1335 yl) carbonyl] amino} phenyl)-N-(4-methylbenzyl)-lH-pyrazole-l-carboxamide N- (2-chlorobenzyl)-5-cyclopropyl-3- (2-hydroxy-4-f [ (l-methyl-lH-pyrrol-2- 1336 yl) carbonyl amino henyl)-1H-yrazole-1-carboxamide 5-cyclopropyl-N-(4-fluorobenzyl)-3-(2-hydroxy-4- {[(1-methyl-lH-pyrrol-2- 1337 yl) carbonyl] amino henyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-N- (3, 4-dichlorobenzyl)-3- (2-hydroxy-4-j (1-methyl-1H-pyrrol-2- 1338 yl) carbonyl] amino henyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3-(2-hydroxy-4- { [(1-methyl-lH-pyrrol-2- 1339 yl) carbonyl] amino henyl)-N- (4-methoxybenzyl)-lH-pyrazole-l-carboxamide N- (sec-butyl)-5-cyclopropyl-3- (2-hydroxy-4-f [ (1-methyl-1 H-pyrrol-2- 1340 yl) carbonyl amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-N- (2-fluorobenzyl)-3- (2-hydroxy-4- { [ (l-methyl-lH-pyrrol-2- 1341 yl) carbonyl] amino} phenyl)-1 H-pyrazole-1-carboxamide 5-cyclopropyl-N-(3-fluorobenzyl)-3-(2-hydroxy-4- {[(1-methyl-lH-pyrrol-2- 1342 yl) carbonyl] amino henyl)-lH-pyrazole-l-carboxamide N, 5-dicyclopropyl-3-(2-hydroxy-4- {[(1-methyl-lH-pyrrol-2- 1343 yl) carbonyl] amino} phenyl)-1H-pyrazole-1-carboxamide 5-cyclobutyl-3-(2-hydroxy-4- {[(1-methyl-lH-pyrrol-2- 1344 yl) carbonyl] amino henyl)-N-isopropyl-lH-pyrazole-l-carboxamide 5-cyclobutyl-N-ethyl-3- (2-hydroxy-4- { [ (1-methyl-IH-pyrrol-2- 1345 yl) carbonyllamino} shenyl)-lH-nyrazole-l-carboxamide N-allyl-5-cyclobutyl-3- (2-hydroxy-4- f [ (1-methyl-1H-pyrrol-2- 1346 yl) carbonyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- (2-hydroxy-4- { [ (1-methyl-1H-pyrrol-2- 1347 yl) carbonyl] amino} phenyl)-N-propyl-lH-pyrazole-l-carboxamide N-benzyl-5-cyclobutyl-3- (2-hydroxy-4- { [ (l-methyl-lH-pyrrol-2- 1348 yl) carbonyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- (2-hydroxy-4-f [ (I-methyl-IH-pyrrol-2- 1349 yl) carbonyl] amino} phenyl)-N-(2-phenylethyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- (2-hydroxy-4- { [ (1-methyl-1H-pyrrol-2- 1350 yl) carbonyl] amino}phenyl)-N- (2-methylbenzyl)-lH-pyrazole-I-carboxamide 5-cyclobutyl-3- (2-hydroxy-4-f [ (1-methyl-1H-pyrrol-2- 1351 yl) carbonyl] amino henyl)-N- (3-methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3-(2-hydroxy-4- {[(1-methyl-lH-pyrrol-2- 1352 yl) carbonyl3amino} phenyl)-N-(4-methylbenzyl)-lH-pyrazole-l-carboxamide N- (2-chlorobenzyl)-5-cyclobutyl-3- (2-hyQroxy-4- { [ (l-methyl-lH-pyrrol-2- 1353 yl) carbonyl] amino phenyl)-1H-pyrazole-1-carboxamide 5-cyclobutyl-N- (4-fluorobenzyl)-3- (2-hydroxy-4- { [ (1-methyl-1H-pyrrol-2- 1354 yl) carbonyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-N-(3, 4-dichlorobenzyl)-3-(2-hydroxy-4- {[(1-methyl-lH-pyrrol-2- 1355 yl) carbonyl] amino} phenyl)-1 H-pyrazole-1-carboxamide 5-cyclobutyl-3- (2-hydroxy-4- f [ (1-methyl-1 H-pyrrol-2- 1356 yl) carbonyl] amino henyl)-N-4-methoxybenzyl)-1H-yrazole-1-carboxamide N- (sec-butyl)-5-cyclobutyl-3- (2-hydroxy-4- f [ (1-methyl-1H-pyrrol-2- 1357 yl) carbonyl] amino} shenyl)-lH-nyrazole-l-carboxamide 5-cyclobutyl-N-(2-fluorobenzyl)-3-(2-hydroxy-4- {[(1-methyl-lH-pyrrol-2- 1358 yl) carbonyl amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-N- (3-fluorobenzyl)-3- (2-hydroxy-4- { [ (1-methyl-1 H-pynrol-2- 1359 yl) carbonyl] amino} phenyl)-1H-pyrazole-1-carboxamide 5-cyclobutyl-N-cyclopropyl-3- (2-hydroxy-4- { [ (1-methyl-1 H-pyrrol-2- 1360 yl) carbonyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3-(2-hydroxy-4- {[(1-methyl-lH-pyrrol-2- 1361 yl) carbonyl] amino henyl)-N-isopropyl-2H-pyrazole-1-carboxamide 5-cyclopentyl-N-ethyl-3-(2-hydroxy-4- {[(1-methyl-lH-pyrrol-2- 1362 yl) carbonyl] amino henyl)-lH-yrazole-l-carboxamide N-allyl-5-cyclopentyl-3-(2-hydroxy-4- {[(1-methyl-lH-pyrrol-2- 1363 yl) carbonyl] amino} phenyl)-1H-pyrazole-1-carboxamide 5-cyclopentyl-3-(2-hydroxy-4- {[(1-methyl-lH-pyrrol-2- 1364 yl) carbonylJainino} phenyl)-N-propyl-lH-pyrazole-l-carboxamide N-benzyl-5-cyclopentyl-3-(2-hydroxy-4- {[(1-methyl-lH-pyrrol-2- 1365 yl) carbonyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3-(2-hydroxy-4- {[(l-methyl-lH-pyrrol-2- 1366 yl) carbonyl phenyl)-N-(2-phenylethyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3-(2-hydroxy-4- {[(1-methyl-lH-pyrrol-2- 1367 yl) carbonyl] amino} phenyl)-N-(2-methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3-(2-hydroxy-4- {[(i-methyl-lH-pyrrol-2- 1368 yl) carbonyl] aminolphenyl)-N- (3-methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3-(2-hydroxy-4- {[(1-methyl-lH-pyrrol-2- 1369 yl) carbonyllaminolphenyl)-N- (4-methylbenzyl)-IH-pyrazole-l-carboxamide N- (2-chlorobenzyl)-5-cyclopentyl-3- (2-hydroxy-4- { [ (1-methyl-1 H-pyrrol-2- 1370 yl) carbonyl] amino} phenyl)-IH-pyrazole-1-carboxamide 5-cyclopentyl-N- (4-fluorobenzyl)-3- (2-hydroxy-4- { [ (l-methyl-lH-pyrrol-2- 1371 yl) carbonyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-N-(3, 4-dichlorobenzyl)-3-(2-hydroxy-4- {[(1-methyl-lH-pyrrol-2- 1372 yl) carbonyl] amino phenyl)-1H-pyrazole-1-carboxamide 5-cyclopentyl-3-(2-hydroxy-4- {[(1-methyl-lH-pyrrol-2- 1373 yl) carbonyl] amino} phenyl)-N-(4-methoxybenzyl)-lH-pyrazole-l-carboxamide N-(sec-butyl)-5-cyclopentyl-3-(2-hydroxy-4- {[(1-methyl-lH-pyrrol-2- 1374 yl) carbonyl] amino} phenyl)-1 H-pyrazole-1-carboxamide 5-cyclopentyl-N- (2-fluorobenzyl)-3- (2-hydroxy-4- { [ (l-methyl-lH-pyrrol-2- 1375 yl) carbonyl] amino} phenyl)-lH-pyrazole-l-caxboxamide 5-cyclopentyl-N-(3-fluorobenzyl)-3-(2-hydroxy-4- {[(1-methyl-lH-pyfrol-2- 1376 yl) carbonyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-N-cyclopropyl-3- (2-hydroxy-4- { [ (1-methyl-1H-pyrrol-2- 1377 yl) carbonyl] amino} phenyl)-IH-pyrazole-1-carboxamide 3- {5-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N-isopropyl-lH- 1378 pyrazole-1-carboxamide 3- {5-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N-ethyl-lH- 1379 pyrazole-1-carboxamide N-allyl-3- {5- [ (2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-lH- 1380 pyrazole-1-carboxamide 3- {5-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N-propyl-lH- 1381 pyrazole-1-carboxamide N-benzyl-3- {5-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-lH- 1382 pyrazole-1-carboxamide s 3-f{5- [ (2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (2- 1383 phenylethyl)-1 H-pyrazole-1-carboxamide 3- {5- [ (2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (2- 1384 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {5-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N-(3- 1385 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {5- [ (2-chlorobenzoyl) ammo]-2-hydroxyphenyl}-5-cyclopropyl-N- (4- 1386 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {5-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-N-(2-chlorobenzyl)-5- 1387 cyclolmyl-lH-pyrazole-l-carboxamide 3- {5-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N-(4- 1388 fluorobenzyl)-IH-pyrazole-1-carboxamide 3- {5-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N-(3, 4- 1389 dichlorobenzyl-lH-pyrazole-l-carboxamide 3- {5- [ (2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (4- 1390 methoxybenzyl)-lH-pyrazole-l-carboxamide N-(sec-butyl)-3- {5-[(2-chlorobenzoyl) arnino]-2-hydroxyphenyl}-5-cyclopropyl- 1391 IH-pyrazole-l-carboxamide 3- {5-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N-(2- 1392 fluorobenzyl)-lE-pyrazole-l-carboxamide A 3- {5-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N-(3- 1393 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {5-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-N, 5-dicyclopropyl-lH- 1394 pyrazole-1-carboxamide 3- {5-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-isopropyl-lH- 1395 pyrazole-I-carboxamide 3- {5-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-ethyl-lH- 1396 pyrazole-1-carboxamide N-allyl-3- {5-[(2-chlorobenzoyl) arnino]-2-hydroxyphenyl}-5-cyclobutyl-lH- 1397 pyrazole-1-carboxamide 3- {5-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-propyl-lH- 1398 pyrazole-1-carboxamide N-benzyl-3- 5- [ (2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-1H- 1399 pyrazole-1-carboxamide 3- {5- [ (2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (2- 1400 phenylethyl)-lH-pyrazole-l-carboxamide 3- {5-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-(2- 1401 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {5-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-(3- 1402 methylbenzyl)-1 H-pyrazole-1-carboxamide 3-f5- [ (2-eblorobenzoyl) amino]-2-hydroxyphenyll-5-cyclobutyl-N- (4- 1403 methylbenzyl)-1 H-pyrazole-1-carboxamide 3- {5-[(2-chlorobenzoyl) arnino]-2-hydroxyphenyl}-N-(2-chlorobenzyl)-5- 1404 cyclobutyl-lH-pyrazole-l-carboxaxnide 3- {5-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-(4- 1405 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {5-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-(3, 4- 1406 dichlorobenzyl)-lH-yrazole-1-carboxamide 3- {5-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-(4- 1407 methoxybenzyl)-lH-pyrazole-1-carboxamide N- (see-butyl)-3-f5- [ (2-chlorobenzoyl) arnino]-2-hydroxyphenyl)-5-cyclobutyl-lH- 1408 pyrazole-1-carboxamide 3- {5-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-(2- 1409 fluorobenzyl)-lH-pyrazole-l-carboxamide 3-15- [ (2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (3- 1410 fluorobenzyl)-IH-pyrazole-l-carboxamide 3-{5-[(2-chlorobenzoyl) arnino]-2-hydroxyphenyl}-5-cyclobutyl-N-cyclopropyl- 1411 lH-pyrazole-1-carboxamide 3- {5-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-isopropyl-1H- 1412 yrazole-1-carboxamide 3-{5-[(2-chlorobenzoyl) arnino]-2-hydroxyphenyl}-5-cyclopentyl-N-ethyl-lH- 1413 pyrazole-1-carboxamide N-allyl-3- {5- [ (2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-lH- 1414 pyrazole-1-carboxamide 3- {5- [ (2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-propyl-lH- 1415 pyrazole-1-carboxamide N-benzyl-3- {5-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-lH- 1416 yrazole-1-carboxamide 3- {5-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-(2- 1417 phenylethyl)-1 H-pyrazole-1-carboxamide 3- {5-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-(2- 1418 methylbenzyl)-IH-pyrazole-1-carboxarnide 3- {5-[(2-chlorobenzoyl) arnino]-2-hydroxyphenyl}-5-cyclopentyl-N-(3- 1419 methylbenzyl)-lH-yrazole-l-carboxamide 3- {5- [ (2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (4- 1420 methylbenzyl)-lH-pyrazole-1-carboxamide 3- {5-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-N-(2-chlorobenzyl)-5- 1421 cyclooentyl-lH-Dyrazole-l-carboxarnide 3- {5- [ (2-chlorobeuzoyl) ammo]-2-hydroxyphenyl}-5-cyclopentyl-N- (4- 1422 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {5- [ (2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (3, 4- 1423 dichlorobenzyl)-1 H-pyrazole-1-carboxamide 3- {5- [ (2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (4- 1424 methoxybenzyl)-lH-pyrazole-l-carboxamide N-(sec-butyl)-3- {5-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl- 1425 IH-yrazole-l-carboxamide 3- {5-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-(2- 1426 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {5-[(2-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-(3- 1427 fluorobenzyl)-lH-pyrazole-1-carboxamide 3- {5- [ (2-chlorobenzoyl) amino]-2-hydrox henyll-5-cyclopentyl-N-cyclopropyl- 1428 IH-pyrazole-l-carboxamide 5-cyclopropyl-3- {5- [ (2, 6-dichlorobenzoyl) arnino]-2-hydroxyphenyl}-N-isopropyl- 1429 1 H-pyrazole-1-carboxamide 5-cyclopropyl-3- {5-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-ethyl-lH- 1430 pyrazole-l-carboxamide N-allyl-5-cyclopropyl-3- {5- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-lH- 1431 pyrazole-l-carboxamide 5-cyclopropyl-3- {5- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-propyl- 1432 1H-pyrazole-l-carboxamide N-benzyl-5-cyclopropyl-3- {5-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}- 1433 IH-pyrazole-l-carboxamide 5-cyclopropyl-3- {5- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-(2- 1434 henylethyl)-1H-yrazole-1-carboxamide 5-cyclopropyl-3- {5- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (2- 1435 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {5-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-(3- 1436 methylbenzyl)-lH-yrazole-l-carboxamide 5-cyclopropyl-3-{5-[(2, 6-dichlorobenzoyl) amino] 2 hydroxyphenyl}-N-(4- 1437 methylbenzyl)-lH-pyrazole-l-carboxamide N-(2-chlorobenzyl)-5-cyclopropyl-3- {5-[(2, 6-dichlorobenzoyl) amino]-2- 1438 hydroxyphenyl}-IH-pyrazole-l-carboxamide 5-cyclopropyl-3- {5-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-(4- 1439 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {5- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (3, 4- 1440 dichlorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {5- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (4- 1441 methoxybenzyl)-1 H-pyrazole-1-carboxamide N-(sec-butyl)-5-cyclopropyl-3- {5-[(2, 6-dichlorobenzoyl) amino]-2- 1442 hydroxyphenyl-IH-pyrazole-1-carboxamide 5-cyclopropyl-3- {5- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (2- 1443 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {5-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-(3- 1444 fluorobenzyl)-lH-Dyrazole-l-carboxamide A N, 5-dicyclopropyl-3- {5- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-IH- 1445 pyrazole-1-carboxamide 5-cyclobutyl-3- {5-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-isopropyl- 1446 IH-pyrazole-1-carboxamide 5-cyclobutyl-3- {5-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-ethyl-lH- 1447 pyrazole-1-carboxamide N-allyl-5-cyclobutyl-3- {5-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-lH- 1448 pyrazole-1-carboxamide 5-cyclobutyl-3- {5- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-propyl-lH- 1449 pyrazole-1-carboxamide A N-benzyl-5-cyclobutyl-3- {5-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-1H- 1450 pyrazole-1-carboxamide 5-cyclobutyl-3- {5-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (2- 1451 phenylethyl)-1 H-pyrazole-1-carboxamide 5-cyclobutyl-3- 5- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (2- 1452 methylbenzyl)-1 H-pyrazole-1-carboxamide 5-cyclobutyl-3- {5- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (3- 1453 methylbenzyl)-lH-pyrazole-1-carboxamide 5-cyclobutyl-3-f 5- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (4- 1454 methylbenzyl)-lH-pyrazole-1-carboxamide N- (2-chlorobenzyl)-5-cyclobutyl-3- {5- [ (2, 6-dichlorobenzoyl) amino]-2- 1455 hydroxyphenyl}-1 H-pyrazole-1-carboxamide 5-cyclobutyl-3- {5- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (4- 1456 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3-f 5- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (3, 4- 1457 dichlorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {5-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-(4- 1458 methoxybenzyl)-lH-pyrazole-l-carboxamide w N- (sec-butyl)-5-cyclobutyl-3- {5- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}- 1459 1H-pyrazole-l-carboxamide 5-cyclobutyl-3- {5-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-(2- 1460 fluorobenzyl)-lH-Pyrazole-l-carboxamide 5-cyclobutyl-3- {5-[(2, 6-dichlorobenzoyl) amino3-2-hydroxyphenyl}-N-(3- 1461 fluorobenzyl)-1H-yrazole-1-carboxamide 5-cyclobutyl-N-cyclopropyl-3- {5-[(2, 6-dichlorobenzoyl) amino]-2- 1462 hydroxyphenyl-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {5- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-isopropyl- 1463 IH-pyrazole-l-carboxamide 5-cyclopentyl-3- {5-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-ethyl-lH- 1464 pyrazole-1-carboxamide N-allyl-5-cyclopentyl-3- {5- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-1H- 1465 pyrazole-l-carboxamide 5-cyclopentyl-3- {5- [. (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-propyl- 1466 1H-pyrazole-l-carboxamide N-benzyl-5-cyclopentyl-3- {5-[(2, 6-dichlorobenzoyl) amnino]-2-hydroxyphenyl}- 1467 IH-pyrazole-l-carboxamide 5-cyclopentyl-3- {5- [ (2, 6-dichIorobenzoyl) amino]-2-hydroxyphenyl}-N- (2- 1468 phenylethyl)-1 H-pyrazole-1-carboxamide 5-cyclopentyl-3- {5- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (2- 1469 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {5- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-(3- 1470 methylbenzyl)-1 H-pyrazole-1-carboxamide 5-cyclopentyl-3- {5-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl3-N-(4- 1471 methylbenzyl)-lH-pyrazole-l-carboxamide N-(2-chlorobenzyl)-5-cyclopentyl-3- {5-[(2, 6-dichlorobenzoyl) amino]-2- 1472 hydrox henyl}-1H-yrazole-1-caxboxamide 5-cyclopentyl-3- {5- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (4- 1473 fluorobenzyl)-1 H-syrazole-1-carboxamide 5-cyclopentyl-3- {5- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (3, 4- 1474 dichlorobenzyl)-IH-pyrazole-l-carboxamide 5-cyclopentyl-3- {5- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N- (4- 1475 methoxybenzyl)-lH-pyrazole-1-carboxamide N- (sec-butyl)-5-cyclopcntyl-3- {5- [ (2, 6-dichlorobenzoyl) amino-2- 1476 hydroxyphenyl}-lH-pyrazole-1-carboxamide 5-cyclopentyl-3- {5- [ (2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-(2- 1477 fluorobenzyl)-1H-pyrazole-1-carboxamide 5-cyclopentyl-3- {5-[(2, 6-dichlorobenzoyl) amino]-2-hydroxyphenyl}-N-(3- 1478 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-N-cyclopropyl-3- {5- [ (2, 6-dichlorobenzoyl) amino]-2- 1479 hydroxyphenyl}-lH-pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-5-[(2-methoxybenzoyl) amino] phenyl}-N-isopropyl- 1480 IH-pyrazole-1-carboxamide 5-cyclopropyl-N-ethyl-3- {2-hydroxy-5-[(2-methoxybenzoyl) aminogphenyl}-1H- 1481 Pyrazole-l-carboxatnide N-allyl-5-cyclopropyl-3- {2-hydroxy-5-[(2-methoxybenzoyl) amino] phenyl}-1H- 1482 pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-5-[(2-methoxybenzoyl) amino] phenyl}-N-propyl-1 H- 1483 yrazole-1-carboxamide N-benzyl-5-cyclopropyl-3-2-hydroxy 5- [ (2-methoxybenzoyl) amino] phenyl-1H- 1484 pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-5-[(2-methoxybenzoyl) amino] phenyl}-N- (2- 1485 phenylethyl)-lH-pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-5-[(2-methoxybenzoyl) amino] phenyl}-N-(2- 1486 methylbenzyl)-1 H-pyrazole-1-carboxamide 5-cyclopropyl-3- 2-hydroxy-5- [ (2-methoxybenzoyl) amino] phenyl}-N- (3- 1487 methylbenzyl)-lH-pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-5-[(2-methoxybenzoyl) amino] phenyl}-N-(4- 1488 methylbenzyl)-1H-yrazole-1-carboxamide N-(2-chlorobenzyl)-5-cyclopropyl-3- {2-hydroxy-5-[(2- 1489 methoxybenzoyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclopropyl-N-(4-fluorobenzyl)-3- {2-hydroxy-5-[(2- 1490 methoxybenzoyl) amino] phenyl}-lH-pyrazole-l-carboxarnide 5-cyclopropyl-N- (3, 4-dichlorobenzyl)-3- {2-hydroxy-5- [ (2- 1491 methoxybenzoyl) amino phenyl}-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {2-hydroxy-5-[(2-methoxybenzoyl) amino3phenyl}-N-(4- 1492 methoxybenzyl)-1 H-pyrazole-l-carboxamide N- (sec-butyl)-5-cyclopropyl-3- {2-hydroxy-5- [ (2-methoxybenzoyl) amino] phenyl}- 1493 1 H-pyrazole-1-carboxamide 5-cyclopropyl-N-(2-fluorobenzyl)-3- {2-hydroxy-5-[(2- 1494 methoxybenzoyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclopropyl-N- (3-fluorobenzyl)-3- {2-hydroxy-5- [ (2-. 1495 methoxybenzoyl) amino] phenyl}-lH-pyrazole-l-carboxamide N, 5-dicyclopropyl-3- {2-hydroxy-5-[(2-methoxybenzoyl) amino] phenyl}-1H- 1496 pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-5-[(2-methoxybenzoyl) amino] phenyl}-N-isopropyl- 1497 IH-pyrazole-l-carboxamide 5-cyclobutyl-N-ethyl-3- {2-hydroxy-5-[(2-methoxybenzoyl) amino] phenyl}-1H- 1498 pyrazole-1-carboxamide N-allyl-5-cyclobutyl-3- {2-hydroxy-5- [ (2-methoxybenzoyl) amino] phenyl}-lH- 1499 pyrazole-l-carboxamide 5-cyclobutyl-3- {2-hydroxy-5-[(2-methoxybenzoyl) amino] phenyl}-N-propyl-lH- 1500 pyrazole-1-carboxamide N-benzyl-5-cyclobutyl-3- {2-hydroxy-5- [(2-methoxybenzoyl) amino] phenyl}-lH- 1501 pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-5- [ (2-methoxybenzoyl) amino] phenyl}-N- (2- 1502 shenylethyl)-lH-syrazole-1-carboxarnide 5-cyclobutyl-3- {2-hydroxy-5-[(2-methoxybenzoyl) amino] phenyl}-N-(2- 1503 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {2-hydroxy-5-[(2-methoxybenzoyl) amino] phenyl}-N-(3- 1504 methvlbenzyl)-lH-yrazole-l-carboxamide 5-cyclobutyl-3- {2-hydroxy-5-[(2-methoxybenzoyl) amino] phenyl}-N-(4- 1505 methylbenzyl)-lH-syrazole-l-calboxamide N-(2-chlorobenzyl)-5-cyclobutyl-3- {2-hydroxy-5-[(2- 1506 methoxybenzoyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclobutyl-N-(4-uorobenzyl)-3- {2-hydroxy-5-[(2- 1507 methoxybenzoyl) amino phenyl-lH-pyrazole-l-carboxamide 5-cyclobutyl-N- (3, 4-dichlorobenzyl)-3- {2-hydroxy-5- [ (2- 1508 methoxybenzoyl) amino] phenyl}-lH-pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-5- [ (2-methoxybenzoyl) amino] phenyl}-N- (4- 1509 methoxybenzyl)-lH-pyrazole-l-carboxamide N-(sec-butyl)-5-cyclobutyl-3-{2-hydroxy 5-[(2-methoxybenzoyl) amino] phenyl}- 1510 IH-pyrazole-l-carboxamide 5-cyclobutyl-N-(2-fluorobenzyl)-3- {2-hydroxy-5-[(2- 1511 methoxybenzoyl) aminophenyl-lH-pyrazole-1-carboxamide 5-cyclobutyl-N-(3-fluorobenzyl)-3- {2-hydroxy-5-[(2- 1512 methoxybenzoyl) amino] Phenyl}-l H-Pyrazole-1-carboxamide z A 5-cyclobutyl-N-cyclopropyl-3- {2-hydroxy-5-[(2-methoxybenzoyl) amino] phenyl}- 1513 1H-pyrazole-l-carboxamide x 5-cyclopentyl-3- {2-hydroxy-5-[(2-methoxybenzoyl) amino] phenyl}-N-isopropyl- 1514 1H-yrazole-1-carboxamide 5-cyclopentyl-N-ethyl-3- {2-hydroxy-5-[(2-methoxybenzoyl) amino] phenyl}-1H- 1515 pyrazole-1-carboxamide N-allyl-5-cyclopentyl-3- {2-hydroxy-5-[(2-methoxybenzoyl) amino] phenyl}-lH- 1516 pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-5-[(2-methoxybenzoyl) amino] phenyl}-N-propyl-lH- 1517 pyrazole-1-carboxamide N-benzyl-5-cyclopentyl-3- {2-hydroxy-5-[(2-methoxybenzoyl) amino] phenyl}-lH- 1518 pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-5-[(2-methoxybenzoyl) amino] phenyl}-N-(2- 1519 phenylethyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {2-hydroxy-5-[(2-methoxybenzoyl) amino] phenyl}-N-(2- 1520 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {2-hydroxy-5-[(2-methoxybenzoyl) amino] phenyl}-N- (3- 1521 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {2-hydroxy-5-[(2-methoxybenzoyl) amino3phenyl}-N-(4- 1522 methylbenzyl)-IH-pyrazole-1-carboxamide N-(2-chlorobenzyl)-5-cyclopentyl-3- {2-hydroxy-5-[(2- 1523 methoxybenzoyl) amino phenyl}-lH-pyrazole-l-carboxamide 5-cyclopentyl-N- (4-fluorobenzyl)-3- {2-hydroxy-5- [ (2- 1524 methoxybenzoyl) amino henyl}-IH-pyrazole-1-carboxamide 5-cyclopentyl-N- (3, 4-dichlorobenzyl)-3- {2-hydroxy-5- [ (2- 1525 methoxybenzoyl) amino] phenyl-lH-pyrazole-1-carboxamide 5-cyclopentyl-3-{2-hydroxy-5-[(2-methoxybenzoyl) amino] phenyl}-N-(4- 1526 methoxybenzyl)-lH-yrazole-l-carboxamide N-(sec-butyl)-5-cyclopentyl-3- {2-hydroxy-5-[(2-methoxybenzoyl) amino3phenyl}- 1527 IH-pyrazole-l-carboxamide 5-cyclopentyl-N-(2-fluorobenzyl)-3- {2-hydroxy-5-[(2- 1528 methoxybenzoyl) amino H-syrazole-1-carboxamide 5-cyclopentyl-N- (3-fluorobenzyl)-3- {2-hydroxy-5- [ (2- 1529 methoxybenzoyl) amino] phenyl}-1 H-pyrazole-1-carboxamide _ _ 5-cyclopentyl-N-cyclopropyl-3- {2-hydroxy-5-[(2- 1530 methoxybenzoyl) amino phenyl}-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {2-hydroxy-5-[(2-methylbenzoyl) asnino] phenyl}-N-isopropyl- 1531 IH-pyrazole-l-carboxamide 5-cyclopropyl-N-ethyl-3- {2-hydroxy-5-[(2-methylbenzoyl) amino] phenyl}-1H- 1532 pyrazole-l-carboxamide N-allyl-5-cyclopropyl-3- {2-hydroxy-5-[(2-methylbenzoyl) amino] phenyl}-lH- 1533 pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-5-[(2-methylbenzoyl) amino] phenyl}-N-propyi-1H- 1534 pyrazole-l-carboxamide N-benzyl-5-cyclopropyl-3- {2-hydroxy-5-[(2-methylbenzoyl) aminojphenyl}-1H- 1535 pyrazole-l-carboxamide 5-cyclopropyl-3- {2-hydroxy-5-[(2-methylbenzoyl) aminogphenyl}-N-(2- 1536 phenylethyl)-1 H-pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-5- [ (2-methylbenzoyl) amino] phenyl}-N- (2- 1537 methylbenzyl)-1 H-pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-5-[(2-methylbenzoyl) amino lphenyl}-N-(3- 1538 methylbenzyl)-1H-pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-5-[(2-methylbenzoyl) aminoaphenyl}-N-(4- 1539 methylbenzyl)-lH-pyrazole-1-carboxamide N- (2-chlorobenzyl)-5-cyclopropyl-3- {2-hydroxy-5- [ (2- 1540 methylbenzoyl) amino] phenyl-1H-pyrazole-1-carboxamide 5-cyclopropyl-N-(4-fluorobenzyl)-3- {2-hydroxy-5-[(2- 1541 methylbenzoyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclopropyl-N- (3, 4-dichlorobenzyl)-3- {2-hydroxy-5-[(2- 1542 methylbenzoyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {2-hydroxy-5-[(2-methylbenzoyl) amino] phenyl}-N-(4- 1543 methoxybenzyl)-1 H-pyrazole-1-carboxamide N- (sec-butyl)-5-cyclopropyl-3- {2-hydroxy-5- [ (2-methylbenzoyl) amino] phenyl}- 1544 lH-pyrazole-1-carboxamide 5-cyclopropyl-N- (2-fluorobenzyl)-3- {2-hydroxy-5- [ (2- 1545 methylbenzoyl) aminogphenyl}-1 H-pyrazole-1-carboxainide 5-cyclobutyl-3- {2-hydroxy-5-[(2-methylbenzoyl) amino] phenyl}-N-isopropyl-lH- 1546 pyrazole-I-carboxamide N, 5-dicyclopropyl-3- {2-hydroxy-5-[(2-methylbenzoyl) amino] phenyl}-1H- 1547 Dyrazole-l-carboxamide A 5-cyclobutyl-3- {2-hydroxy-5-[(2-methylbenzoyl) amino] phenyl}-N-isopropyl-lH- 1548 pyrazole-l-carboxamide 5-cyclobutyl-N-ethyl-3- {2-hydroxy-5- [(2-methylbenzoyl) amino] phenyl}-1 H- 1549 syrazole-l-carboxamide 549 N-allyl-5-cyclobutyl-3- {2-hydroxy-5- [ (2-methylbenzoyl) ammo] phenyl}-lH- 1550 pyrazole-l-carboxamide 5-cyclobutyl-3- {2-hydroxy-5-[(2-methylbenzoyl) amino] phenyl}-N-propyl-lH- 1551 yrazole-1-carboxamide N-benzyl-5-cyclobutyl-3-{2-hydroxy-5-[(2-methylbenzoyl) amino] phenyl}-1H- 1552 pyrazole-l-carboxamide 5-cyclobutyl-3- {2-hydroxy-5-[(2-methylbenzoyl) amino] phenyl}-N-(2- 1553 phenylethyl)-lH-pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-5-[(2-methylbenzoyl) amino] phenyl}-N-(2- 1554 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {2-hydroxy-5-[(2-methylbenzoyl) amino] phenyl}-N-(3- 1555 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {2-hydroxy-5-[(2-methylbenzoyl) amino] phenyl}-N-(4- 1556 methylbenzyl)-lH-pyrazole-l-carboxamide N-(2-chlorobenzyl)-5-cyclobutyl-3- {2-hydroxy-5-[(2- 1557 methylbenzoyl) amino] phenyl-lH-pyrazole-l-carboxamide 5-cyclobutyl-N-(4-fluorobenzyl)-3- {2-hydroxy-5-[(2- 1558 methylbenzoyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclobutyl-N-(3, 4-dichlorobenzyl)-3- {2-hydroxy-5-[(2- 1559 methylbenzoyl) aminophenyl}-1H-pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-5-[(2-methylbenzoyl) amino] phenyl}-N-(4- 1560 methoxybenzyl)-1 H-pyrazole-1-carboxamide N-(sec-butyl)-5-cyclobutyl-3- {2-hydroxy-5-[(2-methylbenzoyl) amino] phenyl}- 1561 1H-pyrazole-1-carboxamide 5-cyclobutyl-N-(2-fluorobenzyl)-3- {2-hydroxy-5-[(2- 1562 methylbenzoyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {2-hydroxy-5-[(2-methylbenzoyl) amino] phenyl}-N-isopropyl- 1563 1H-pyrazole-1-carboxamide 5-cyclobutyl-N-cyclopropyl-3- {2-hydroxy-5- [ (2-methylbenzoyl) amino] phenyl}- 1564 IH-pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-5-[(2-methylbenzoyl) amino] phenyl}-N-isopropyl- 1565 IH-pyrazole-l-carboxamide 5-cyclopentyl-N-ethyl-3- {2-hydroxy-5-[(2-methylbenzoyl) amino] phenyl}-1H- 1566 pyrazole-1-carboxamide s N-allyl-5-cyclopentyl-3- {2-hydroxy-5-[(2-methylbenzoyl) amino] phenyl}-1H- 1567 pyrazole-1-carboxamide s 5-cyclopentyl-3- {2-hydroxy-5-[(2-methylbenzoyl) amino] phenyl}-N-propyl-lH- 1568 pyrazole-1-carboxamide N-benzyl-5-cyclopentyl-3- {2-hydroxy-5- [ (2-methylbenzoyl) amino] phenyl}-1 H- 1569 pyrazole-l-carboxamide A 5-cyclopentyl-3- {2-hydroxy-5-[(2-methylbenzoyl) amino] phenyl}-N- (2- 1570 phenylethyl)-IH-pyrazole-l-carboxamide 5-cyclopentyl-3- {2-hydroxy-5- [ (2-methylbenzoyl) amino] phenyl}-N- (2- 1571 methylbenzyl)-1 H-pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-5-[(2-methylbenzoyl) amino] phenyl}-N-(3- 1572 methylbenzyl)-1 H-pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-5-[(2-methylbenzoyl) amino] phenyl}-N-(4- 1573 methylbenzyl)-1 H-pyrazole-1-carboxamide N-(2-chlorobenzyl)-5-cyclopentyl-3- {2-hydroxy-5-[(2- 1574 methylbenzoyl) amino henyl}-1H-pyrazole-1-carboxamide 5-cyclopentyl-N-(4-fluorobenzyl)-3- {2-hydroxy-5-[(2- 1575 methylbenzoyl) amino] phenyl-lH-pyrazole-l-carboxamide 5-cyclopentyl-N- (3, 4-dichlorobenzyl)-3- f 2-hydroxy-5- [ (2- 1576 methylbenzoyl) amino] phenyl}-lH-pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-5-[(2-methylbenzoyl) amino] phenyl}-N-(4- 1577 methoxybenzyl)-lH-pyrazole-l-carboxamide N-(sec-butyl)-5-cyclopentyl-3- {2-hydroxy-5-[(2-methylbenzoyl) amino] phenyl}- 1578 lH-pyrazole-l-carboxamide 5-cyclopentyl-N-(2-fluorobenzyl)-3- {2-hydroxy-5-[(2- 1579 methylbenzoyl) amino] phenyl-lH-pyrazole-l-carboxamide 5-cyclopentyl-N-(3-fluorobenzyl)-3- {2-hydroxy-5-[(2- 1580 methylbenzoyl) arnino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclopentyl-N-cyclopropyl-3- {2-hydroxy-5-[(2-methylbenzoyl) amino] phenyl}- 1581 1H-pyrazole-l-carboxamide 5-cyclopropyl-3-(2-hydroxy-5- {[3-(trifluoromethyl) benzoyl] amino} phenyi)-N- 1582 isopropyl-lH-pyrazole-l-carboxamide 5-cyclopropyl-N-ethyl-3- (2-hydroxy-5- { [3- 1583 (trifluoromethyl) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide N-allyl-5-cyclopropyl-3-(2-hydroxy-5- {[3- 1584 (trifluoromethyl) benzoyl] amino} phenyl)-1 H-pyrazole-1-carboxamide 5-cyclopropyl-3-(2-hydroxy-5- {[3-(trifluoromethyl) benzoyl] amino} phenyl)-N- 1585 propyl-1H-pyrazole-1-carboxamide s N-benzyl-5-cyclopropyl-3-(2-hydroxy-5- {[3- 1586 (trifluoromethyl) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3-(2-hydroxy-5- {[3-(trifluoromethyl) benzoyl] amino} phenyl)-N-(2- 1587 phenylethyl)-1 H-pyrazole-1-carboxamide 5-cyclopropyl-3-(2-hydroxy-5- {[3-(trifluoromethyl) benzoyl] amino} phenyl)-N- (2- 1588 methylbenzyl)-1 H-pyrazole-1-carboxamide 5-cyclopropyl-3- (2-hydroxy-5- { [3- (trifluoromethyl) benzoyl] amino} phenyl)-N- (3- 1589 methylbenzyl)-IH-pyrazole-l-carboxamide 5-cyclopropyl-3-(2-hydroxy-5- {[3-(trifluoromethyl) benzoyl] arnino} phenyl)-N-(4- 1590 methylbenzyl)-lH-pyrazole-l-carboxamide N-{2-chlorobenzyl)-5-cyclopropyl-3-(2-hydroxy-5- { [3- 1591 (trifluoromethyl) berlzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-N- (4-fluorobenzyl)-3- (2-hydroxy-5- { [3- 1592 (trifluoromethyl) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-N- (3, 4-dichlorobenzyl)-3- (2-hydroxy-5- { [3- 1593 (trifluoromethyl) benzoyl] amino} phenyl)-1H-pyrazole-1-carboxamide 5-cyclopropyl-3-(2-hydroxy-5- {[3-(trifluoromethyl) benzoyl] amino} phenyl)-N- (4- 1594 methoxybenzyl)-IH-pyrazole-l-carboxamide N- (sec-butyl)-5-cyclopropyl-3- (2-hydroxy-5- [3- 1595 (trifluoromethyl) benzoyllamino} phenyl)-lH-pyrazole-l-carboxamide 0 5-cyclopropyl-N- (2-fluorobenzyl)-3- (2-hydroxy-5- { [3- 1596 (trifluoromethyl) benzoyl] amino} phenyl)-1H-pyrazole-1-carboxamide 5-cyclopropyl-N-(3-fluorobenzyl)-3-(2-hydroxy-5- {[3- (trifluoromethyl) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide 1 597 N, 5-dicyclopropyl-3-(2-hydroxy-5- {[3-(trifluoromethyl) benzoyl] amino} phenyl)- 1598 IH-yrazole-l-carboxamide A 5-cyclobutyl-3-(2-hydroxy-5- {[3-(trifluoromethyl) benzoyl] amino} phenyl)-N- 1599 iso ro yl-1H-pyrazole-1-caxboxamide D 5-cyclobutyl-N-ethyl-3- (2-hydroxy-5- { [3- 1600 (tifluoromethyl) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide N-allyl-5-cyclobutyl-3-(2-hydroxy-5- {[3- 1601 (trifluoromethyl) benzoyl amino henyl)-1H-pyrazole-l-carboxamide 5-cyclobutyl-3-(2-hydroxy-5- {[3-(trifluoromethyl) benzoyl] amino} phenyl)-N- 1602 propyl-lH-pyrazole-l-carboxamide N-benzyl-5-cyclobutyl-3-(2-hydroxy-5- {[3 1603 (trifluoromethyl) benzoyl amino phenyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3-(2-hydroxy-5- {[3-(trifluoromethyl) benzoyl] amino} phenyl)-N-(2- 1604 phenylethyl)-lH-pyrazole-l-carboxamide_ _ 5-cyclobutyl-3-(2-hydroxy-5- {[3-(trifluoromethyl) benzoyl] amino} phenyl)-N-(2- 1605 methylbenzyl)-1 H-pyrazole-1-carboxamide 5-cyclobutyl-3-(2-hydroxy-5- {[3-(trifluoromethyl) benzoyl] amino} phenyl)-N- (3- 1606 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3-(2-hydroxy-5- {[3-(trifluoromethyl) benzoyl] amino} phenyl)-N-(4- 1607 methylbenzyl)-lH-pyrazole-l-carboxaxnide N- (2-chlorobenzyl)-5-cyclobutyl-3- (2-hydroxy-5- { [3- 1608 (trifluoromethyl) benzoyl] amino henyl)-1H-pyrazole-1-carboxamide 5-cyclobutyl-N-(4-flnorobenzyl)-3-(2-hydroxy-5- { [3- 1609 (trifluoromethyl) benzoyl] amino henyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-N- (3, 4-dichlorobenzyl)-3- (2-hydroxy-5- { [3- 1610 (trifluoromethyl) benzoylgamino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3-(2-hydroxy-5- {[3-(trifluoromethyl) benzoyl] amino} phenyl)-N-(4- 1611 methoxybenzyl)-lH-pyrazole-l-carboxamide N- (sec-butyl)-5-cyclobutyl-3- (2-hydroxy-5- f [3- 1612 (trifluoromethyl) benzoyl] axnino henyl)-1H-pyrazole-1-carboxamide 5-cyclobutyl-N- (2-fluorobenzyl)-3- (2-hydroxy-5- { [3- 1613 (trifluoromethyl) benzoyl] amino, phenyl)-1H-pyrazole-1-carboxamide 5-cyclobutyl-N- (3-fluorobenzyl)-3- (2-hydroxy-5- { [3- 1614 (trifluoromethyl) benzoyl] amino} phenyl)-1 H-pyrazole-1-carboxamide 5-cyclobutyl-N-cyclopropyl-3- (2-hydroxy-5- { [3- 1615 (trifluoromethyl) benzoyl] amino} phenyl)-1 H-pyrazole-1-carboxamide 5-cyclopentyl-3-(2-hydroxy-5- {[3-(trifluoromethyl) benzoyl] amino} phenyl)-N- 1616 isopropyl-1 H-pyrazole-1-carboxamide 5-cyclopentyl-N-ethyl-3- (2-hydroxy-5- { [3- 1617 (trifluoromethyl) benzoyl] amino} phenyl)-1H-pyrazole-1-carboxamide N-allyl-5-cyclopentyl-3- (2-hydroxy-5- { [3- 1618 (trifluoromethyl) benzoyl] amino} phenyl)-1 H-pyrazole-1-carboxamide 5-cyclopentyl-3-(2-hydroxy-5- {[3-(trifluoromethyl) benzoyl] amino} phenyl)-N- 1619 propyl-lH-pyrazole-l-carboxamide A N-benzyl-5-cyclopentyl-3-(2-hydroxy-5- {[3- 1620 (trifluoromethyl) benzoyl] aminophenyl)-lH-yrazole-l-carboxamide 5-cyclopentyl-3- (2-hydroxy-5- f [3- (trifluoromethyl) benzoyl] amino} phenyl)-N-(2- 1621 phenylethyl)-lH-pyrazole-l-carboxamide Ar 5-cyclopentyl-3-(2-hydroxy-5- {[3-(trifluoromethyl) benzoyl] amino} phenyl)-N-(2- 1622 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- (2-hydroxy-5- { [3- (trifluoromethyl) benzoyl] amino} phenyl)-N- (3- 1623 methylbenzyl)-1 H-pyrazole-1-carboxamide 5-cyclopentyl-3- (2-hydroxy-5- { [3- (trifluoromethyl) benzoyl] amino} phenyl)-N- (4- 1624 methylbenzyl)-lH-pyrazole-l-carboxamide N-(2-chlorobenzyl)-5-cyclopentyl-3-(2-hydroxy-5- { [3- 1625 (trifluoromethyl) benzoyl] amino henyl)-1H-yrazole-1-carboxamide 5-cyclopentyl-N-(4-fluorobenzyl)-3-(2-hydroxy-5- {[3- 1626 (trifluoromethyl) benzoyl] aminophenyl)-1H-pyrazole-l-carboxamide 5-cyclopentyl-N-(3, 4-dichlorobenzyl)-3-(2-hydroxy-5- { [3- 1627 (trifluoromethyl) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- (2-hydroxy-5- { [3- (trifluoromethyl) benzoyl] amino} phenyl)-N- (4- 1628 methoxybenzyl)-lH-pyrazole-l-carboxamide N- (sec-butyl)-5-cyclopentyl-3- (2-hydroxy-5- { [3- 1629 (trifluoromethyl) benzoyl] atnino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-N- (2-fluorobenzyl)-3- (2-hydroxy-5-f [3- 1630 (trifluoromethyl) benzoyl] amino} phenyl)-1H-pyrazole-l-carboxamide 5-cyclopentyl-N- (3-fluorobenzyl)-3- (2-hydroxy-5- { [3- 1631 (trifluoromethyl) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-N-cyclopropyl-3-(2-hydroxy-5- {[3- 1632 (trifluoromethyl) benzoyllaminolshenyl)-lH-Pyrazole-l-carboxamide 3- {5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N-isopropyl-lH- 1633 pyrazole-I-carboxamide 3-15- [ (4-chlorobenzoyl) atninol-2-hydroxyphenyll-5-cyclopropyl-N-ethyl-lH- 1634 pyrazole-l-carboxamide N-allyl-3- {5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-lH- 1635 yrazole-1-carboxamide 3-{5-[(4-chlorobenzoyl) arnino]-2-hydroxyphenyl}-5-cyclopropyl-N-propyl-lH- 1636 pyrazole-l-carboxamide N-benzyl-3- {5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-lH- 1637 pyrazole-1-carboxamide 3- 5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (2- 1638 phenylethyl)-l H-pyrazole-1-carboxamide 3- {5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (2- 1639 methylbenzyl)-1 H-pyrazole-1-carboxamide 3- {5- [ (4-chlorobenzoyI) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (3- 1640 methylbenzyl)-1 H-pyrazole-1-carboxamide 3- {5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (4- 1641 methylbenzyl)-1H-pyrazole-1-carboxamide 3- {5-[(4-chlorobenzoyl) amino]-2-hydroxyphenyl}-N-(2-chlorobenzyl)-5- 1642 cyclopropyl-1 H-pyrazole-1-carboxamide 3- {5-[(4-chlorobenzoyl) arnino]-2-hydroxyphenyl}-5-cyclopropyl-N-(4- 1643 fluorobenzyl)-1 H-pyrazole-1-carboxamide 3- {5- [ (4-chlorobenzoyl) ammo]-2-hydroxyphenyl}-5-cyclopropyl-N- (3, 4- 1644 dichlorobenzyl)-IH-pyrazole-l-carboxamide 3- {5-[(4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N-(4- 1645 methoxybenzyl)-lH-pyrazole-l-carboxamide N- (sec-butyl)-3- {5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl- 1646 1H-pyrazole-1-carboxamide x 3- {5-[(4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N-(2- 1647 fluorobenzyl)-1 H-» yrazole-1-carboxamide 3- {5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (3- 1648 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-N, 5-dicyclopropyl-lH- 1649 oyrazole-1-carboxamìde s 3- {5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-isopropyl-lH- 1650 pyrazole-l-carboxamide 3- {5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-ethyl-lH- 1651 pyrazole-1-carboxamide r N-allyl-3- 5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-lH- 1652 pyrazole-l-carboxamide 3- {5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-propyl-1H- 1653 pyrazole-l-carboxamide N-benzyl-3- {5-[(4-chlorobenzoyl) amino]-2-hydroxyphenyl}-s-cyclobutyl-lH 1654 pyrazole-l-carboxamide 3- {5-[(4-chlorobenzoyl) arnino]-2-hydroxyphenyl}-5-cyclobutyl-N-(2- 1655 phenylethyl)-lH-pyrazole-l-carboxamide __ 3- {5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (2- 1656 methylbenzyl)-lH-pyrazole-1-carboxamide A 3- {5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (3- 1657 methylbenzyl)-1H-pyrazole-1-carboxamide 3-15- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyll-5-cyclobutyl-N- (4- 1658 methylbenzyl-IH-yrazole-1-carboxamide 3-f 5- [ (4-chlorobenzoyl) amino]-2-hydxoxyphenyl}-N- (2-chlorobenzyl)-5- 1659 cyclobutyl-lH-pyrazole-l-carboxamide 3- {5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (4- 1660 fluorobenzyl)-lH-pyrazole-l-carboxamide 3-15- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyll-5-cyclobutyl-N- (3, 4- 1661 dichlorobenzyl)-lH-pyrazole-l-carboxamide 3- {5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (4- 1662 methoxybenzyl)-1 H-pyrazole-1-carboxamide N- (sec-butyl)-3- {5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-lH- 1663 pyrazole-1-carboxamide 3- {5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (2- 1664 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {5-[(4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-(3- 1665 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- 5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-cyclopropyl- 1666 1H-yrazole-1-carboxamide 3- {5-[(4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-isopropyl-lH- 1667 pyrazole-1-carboxamide 3-5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-ethyl-lH- 1668 pyrazole-1-carboxamide N-allyl-3- {5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-IH- 1669 pyrazole-1-carboxamide 3- 5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-propyl-lH- 1670 pyrazole-1-carboxamide N-benzyl-3- {5-[(4-chlorobenzoyl) aminoJ-2-hydroxyphenyl}-5-cyclopentyl-lH- 1671 yrazole-1-carboxamide 3- {5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (2- 1672 phenylethyl)-lH-pyrazole-l-carboxamide v A 3- 5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (2- 1673 methylbenzyl)-1 H-pyrazole-1-carboxamide 3- 5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (3- 1674 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (4- 1675 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {5-[(4-chlorobenzoyl) amino]-2-hydroxyphenyl}-N-(2-chlorobenzyl)-5- 1676 cyclopentyl-lH-pyrazole-l-carboxamide 3- 5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (4- 1677 fluorobenzyl)-IH-pyrazole-1-carboxamide 3- {5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (3, 4- 1678 dichlorobenzyl)-lH-pyrazole-1-carboxamide 3- 5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (4- 1679 methoxybenzyl)-lH-pyrazole-l-carboxamide N- (sec-butyl)-3-15- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl- 1680 IH-pyrazole-1-carboxamide 3- {5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (2- 1681 fluorobenzyl)-lH-pyrazole-1-carboxamide 3- {5-[(4-chlorobenzoyl) atnino]-2-hydroxyphenyl}-5-cyclopentyl-N-(3- 1682 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {5- [ (4-chlorobenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-cyclopropyl- 1683 IH-pyrazole-l-carboxamide 5-cyclopropyl-3- {5- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-isopropyl- 1684 1H-pyrazole-l-carboxamide 5-cyclopropyl-3- {5-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-ethyl-lH- 1685 pyrazole-1-carboxamide N-allyl-5-cyclopropyl-3- {5-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-1H- 1686 pyrazole-l-carboxamide 5-cyclopropyl-3- {5-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-propyl-lH- 1687 pyrazole-1-carboxamide N-benzyl-5-cyclopropyl-3- {5-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-1H- 1688 pyrazole-1-carboxamide 5-cyclopropyl-3- 5- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N- (2- 1689 phenylethyl)-1 H-pyrazole-1-carboxamide 5-cyclopropyl-3- {5- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N- (2- 1690 methylbenzyl)-lH-pyrazole-1-carboxamide 5-cyclopropyl-3- {5-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-(3- 1691 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {5- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N- (4- 1692 methylbenzyl)-1H-pyrazole-1-carboxamide N- (2-chlorobenzyl)-5-cyclopropyl-3- {5- [ (4-ethoxybenzoyl) amino]-2- 1693 hydroxyphenyl}-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {5- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N- (4- 1694 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-N- (3, 4-dichlorobenzyl)-3- {5- [ (4-ethoxybenzoyl) arnino]-2- 1695 hydroxyDhenylT-lH-nyrazole-l-carboxamide A 5-cyclopropyl-3- {5-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-(4- 1696 methoxybenzyl)-lH-pyrazole-l-carboxamide A N- (sec-butyl)-5-cyclopropyl-3- {5- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}- 1697 IH-pyrazole-1-carboxamide A 5-cyclopropyl-3- {5- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N- (2- 1698 fluorobenzyl)-1H-pyrazole-1-carboxamide 5-cyclopropyl-3- {5-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-(3- 1699 fluorobenzyl)-1H-yrazole-1-carboxamide N, 5-dicyclopropyl-3- {5-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-1H- 1700 pyrazole-1-carboxamide 5-cyclobutyl-3- {5-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-isopropyl-lH- 1701 pyrazole-l-carboxamide 5-cyclobutyl-3- {5-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-ethyl-lH- 1702 yrazole-1-carboxamide N-allyl-5-cyclobutyl-3- {5-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-1H- 1703 pyrazole-1-carboxamide 5-cyclobutyl-3- {5- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-propyl-1H- 1704 pyrazole-1-carboxamide N-benzyl-5-cyclobutyl-3- {5-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-1H- 1705 pyrazole-1-carboxamide 5-cyclobutyl-3- {5-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-(2- 1706 phenylethyl)-1 H-pyrazole-1-carboxamide A A 5-cyclobutyl-3- {5-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-(2- 1707 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {5- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N- (3- 1708 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {5-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-(4- 1709 methylbenzyl)-1H-pyrazole-1-carboxamide A N- (2-chlorobenzyl)-5-cyclobutyl-3- {5- [ (4-ethoxybenzoyl) amino]-2- 1710 hydroxyDhenyl}-lH-Dyrazole-l-carboxamide . 5-cyclobutyl-3- {5-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-(4- 1711 fluorobenzyl)-1H-yrazole-1-carboxamide z 5-cyclobutyl-N- (3, 4-dichlorobenzyl)-3- {5- [ (4-ethoxybenzoyl) amino]-2- 1712 hydrox henyl}-1H-pyrazole-1-carboxamide 5-cyclobutyl-3- {5- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N- (4- 1713 methoxybenzyl)-lH-Dyrazole-l-carboxamide N- (sec-butyl)-5-cyclobutyl-3-15- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl)- 1714 IH-pyrazole-l-carboxamide 5-cyclobutyl-3- {5-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-(2- 1715 fluorobenzyl)-1 H-pyrazole-1-carboxamide 5-cyclobutyl-3- {5-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-(3- 1716 fluorobenzyl)-1 H-pyrazole-1-carboxamide 5-cyclobutyl-N-cyclopropyl-3- {5- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}- 1717 IH-pyrazole-l-carboxamide 5-cyclopentyl-3- {5- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-isopropyl-lH- 1718 pyrazole-l-carboxamide 5-cyclopentyl-3- {5- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-ethyl-lH- 1719 yrazole-1-carboxamide N-allyl-5-cyclopentyl-3- {5- [ (4-ethoxybcnzoyl) ammo]-2-hydroxyphenyl}-lH- 1720 pyrazole-1-carboxamide 5-cyclopentyl-3- 5- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-propyl-lH- 1721 pyrazole-l-carboxamide N-benzyl-5-cyclopentyl-3- {5-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-1H- 1722 pyrazole-1-carboxamide 5-cyclopentyl-3- {5-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl3-N-(2- 1723 henylethyl)-1H-yrazole-1-carboxamide 5-cyclopentyl-3- {5-[(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-(2- 1724 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {5- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N- (3- 1725 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {5- [(4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N-(4- 1726 methylbenzyl)-lH-pyrazole-1-carboxamide N- (2-chlorobenzyl)-5-cyclopentyl-3- {5- [ (4-ethoxybenzoyl) amino]-2- 1727 hydroxyphenyl-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {5- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyI}-N- (4- 1728 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-N- (3, 4-dichlorobenzyl)-3- {5- [ (4-ethoxybenzoyl) amino]-2- 1729 hydroxyphenyl}-IH-pyrazole-l-carboxamide 5-cyclopentyl-3- {5-t (4-ethoxybenzoyl) atnino]-2-hydroxyphenyl}-N-(4- 1730 methoxybenzyl)-lH-pyrazole-l-carboxamide N- (sec-butyl)-5-cyclopentyl-3- {5- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}- 1731 1 H-pyrazole-1-carboxamide 5-cyclopentyl-3- {5- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N- (2- 1732 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {5- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}-N- (3- 1733 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-N-cyclopropyl-3- {5- [ (4-ethoxybenzoyl) amino]-2-hydroxyphenyl}- 1734 1H-pyrazole-l-carboxamide 3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N-isopropyl- 1735 IH-pyrazole-l-carboxamide 3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N-ethyl-lH- 1736 pyrazole-1-carboxamide N-allyl-3- {5-[(4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-lH- 1737 pyrazole-1-carboxamide 3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N-propyl-lH- 1738 pyrazole-l-carboxamide N-benzyl-3- 5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-lH- 1739 pyrazole-l-carboxamide 3- {5-[(4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N-(2- 1740 phenylethyl)-lH-pyrazole-l-carboxamide 3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (2- 1741 methylbenzyl)-1H-yrazole-1-carboxamide 3-f5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (3- 1742 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (4- 1743 melylbenzyl)-lH-Dyrazole-1-carboxamide 3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-N- (2-chlorobenzyl)-5- 1744 cyclopropyl-lH-pyrazole-1-carboxamide A X 3-f 5- [ (4-tert-butylbenzoyl) atninol-2-hydroxyphenyll-5-cyclopropyl-N- (4- 1745 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (3, 4- 1746 dichlorobenzyl)-lH-pyrazole-l-carboxamide 3- 5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (4- 1747 methoxybenzyl)-lH-pyrazole-1-carboxamide N-(sec-butyl)-3- {5-[(4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5- 1748 cyclopropyl-lH-pyrazole-l-carboxamide 3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (2- 1749 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {5-[(4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N-(3- 1750 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-N, 5-dicyclopropyl-lH- 1751 pyrazole-l-carboxamide 3- {5-[(4-tert-butylbenzoyl) arnino]-2-hydroxyphenyl}-5-cyclobutyl-N-isopropyl- 1752 1H-yrazole-1-carboxamide 3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-ethyl-lH- 1753 yrazole-1-carboxamide x N-allyl-3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-lH- 1754 pyrazole-l-carboxamide 3- {5-[(4-tert-butyibenzoyl) amino]-2-hydroxyphenyl3-5-cyclobutyl-N-propyl-lH- 1755 pyrazole-l-carboxamide N-benzyl-3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-lH- 1756 pyrazole-l-carboxarnide 3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cycIobutyl-N- (2- 1757 phenylethyl)-IH-pyrazole-l-carboxamide 3- {5- [ (4-tert-butylbenzoyl) arnino]-2-hydroxyphenyl}-5-cyclobutyl-N- (2- 1758 methylbenzyl)-lH-pyrazole-1-carboxamide 3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (3- 1759 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (4- 1760 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-N- (2-chlorobenzyl)-5- 1761 cyclobutyl-1 H-pyrazole-1-carboxamide 3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cycIobutyl-N- (4- 1762 fluorobenzyl)-lH-pyrazole-1-carboxamide 3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl)-5-cyclobutyl-N- (3, 4- 1763 dichlorobenzyl)-lH-pyrazole-1-carboxamide x 3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (4- 1764 methoxybenzyl)-IH-yrazole-1-carboxamide 1 N- (sec-butyl)-3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl- 1765 IH-pyrazole-l-carboxamide 3- {5- [ (4-tert-butylbenzoyl) ammo]-2-hydroxyphenyl}-5-cyclobutyl-N- (2- 1766 fluorobenzyl)-IH-pyrazole-1-carboxamide 3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-cyclopropyl- 1767 1H-pyrazole-1-carboxamide 3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N-cyclopropyl- 1768 IH-pyrazole-l-carboxamide 3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-isopropyl- 1769 IH-pyrazole-l-carboxamide 3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-ethyl-1H- 1770 pyrazole-1-carboxamide N-allyl-3- {5- [ (4-tert-butylbenzoyl) ammo]-2-hydroxyphenyl}-5-cyclopentyl-lH- 1771 yrazole-1-carboxamide 3- {5-[(4-tert-butylbenzoyl) arnino]-2-hydroxyphenyl}-5-cyclopentyl-N-propyl-1H- 1772 pyrazole-1-carboxamide N-benzyl-3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-1 H- 1773 pyrazole-1-carboxamide 3- {5-[(4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-(2- 177 phenylethyl)-IH-pyrazole-1-carboxamide 3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (2- 1775 methylbenzyl)-lH-pyrazole-l-carboxarnide 3-f 5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (3- 1776 methylbenzyl)-lH-pyrazole-1-carboxamide 3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (4- 1777 methylbenzyl)-lH-pyrazole-1-carboxamide 3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-N- (2-chlorobenzyl)-5- 1778 cyclopentyl-IH-pyrazole-1-carboxamide 3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (4- 1779 fluorobenzyl)-IH-pyrazole-l-carboxamide 3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (3, 4- 1780 dichlorobenzyl)-lH-pyrazole-1-carboxamide 3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (4- 1781 methoxybenzyl)-lH-pyrazole-l-carboxamide N- (sec-butyl)-3- {5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl- 1782 I H-pyrazole-1-carboxamide 3- {5-[(4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-(2- 1783 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {5-[(4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-(3- 1784 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- 5- [ (4-tert-butylbenzoyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 1785 cyclopropyl-1H-pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-5- [ (4-methylbenzoyl) ammo] phenyl}-N-isopropyl- 1786 1H-yrazole-1-carboxamide 5-cyclopropyl-N-ethyl-3- {2-hydroxy-5-[(4-methylbenzoyl) aminophenyl}-1H- 1787 pyrazole-1-carboxamide N-allyl-5-cyclopropyl-3- {2-hydroxy-5- [ (4-methylbenzoyl) amino] phenyl}-lH- 1788 pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-5- [ (4-methylbenzoyl) amino] phenyl}-N-propyl-lH- 1789 nyrazole-1-carboxamide N-benzyl-5-cyclopropyl-3- {2-hydroxy-5- [ (4-methylbenzoyl) amino] phenyl}-lH- 1790 Dyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-5- [ (4-methylbenzoyl) amino] phenyl}-N- (2- 1791 phenylethyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {2-hydroxy-5-[(4-methylbenzoyl) amino] phenyl}-N-(2- 1792 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {2-hydroxy-5- [ (4-methylbenzoyl) amino] phenyl-N- (3- 1793 methylbenzyl)-lH-pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-5- [ (4-methylbenzoyl) amino] phenyl}-N- (4- 1794 methylbenzyl)-lH-pyrazole-1-carboxamide N- (2-chlorobenzyl)-5-cyclopropyl-3- {2-hydroxy-5- [ (4- 1795 methylbenzoyl) amino] phenyll-lH-pyrazole-1-carboxamide 5-cyclopropyl-N- (4-fluorobenzyl)-3- {2-hydroxy-5- [ (4- 1796 methylbenzoyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclopropyl-N- (3, 4-dichlorobenzyl)-3- {2-hydroxy-5- [ (4- 1797 methylbenzoyl) amino henyl-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {2-hydroxy-5- [ (4-methylbenzoyl) amino] phenyl}-N- (4- 1798 methoxybenzyl)-1H-pyrazole-1-carboxamide N- (sec-butyl)-5-cyclopropyl-3- {2-hydroxy-5- [ (4-methylbenzoyl) amino] phenyl}- 1799 lH-yrazole-l-carboxamide 5-cyclopropyl-N-(2-fluorobenzyl)-3- {2-hydroxy-5- [(4- 1800 methylbenzoyl) amino phenyl-lH-pyrazole-l-carboxamide 5-cyclopropyl-N- (3-fluorobenzyl)-3- {2-hydroxy-5- [ (4- 1801 methylbenzoyl) amino] phenyl}-1H-pyrazole-1-carboxamide N, 5-dicyclopropyl-3- {2-hydroxy-5- [ (4-methylbenzoyl) amino] phenyl}-lH- 1802 pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-5- [ (4-methylbenzoyl) amino] phenyl}-N-isopropyl-lH- 1803 pyrazole-1-carboxamide 5-cyclobutyl-N-ethyl-3- {2-hydroxy-5-[(4-methylbenzoyl) amino] phenyl}-lH- 1804 pyrazole-1-carboxamide N-allyl-5-cyclobutyl-3- {2-hydroxy-5- [ (4-methylbenzoyl) amino] phenyl}-1H- 1805 pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-5-[(4-methylbenzoyl) amino] phenyl}-N-propyl-lH- 1806 pyrazole-l-carboxamide N-benzyl-5-cyclobutyl-3-{2-hydroxy-5-[(4-methylbenzoyl) amino] phenyl}-1H- 1807 pyrazole-1-carboxarnide 5-cyclobutyl-3- 2-hydroxy-5- [ (4-methylbenzoyl) amino] phenyl}-N- (2- 1808 phenylethyl)-1 H-pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-5- [ (4-methylbenzoyl) amino] phenyl}-N- (2- 1809 methylbenzyl)-1 H-pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-5- [ (4-methylbenzoyl) axnino] phenyl}-N- (3- 1810 methylbenzyl)-1 H-pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-5-[(4-methylbenzoyl) amino] phenyl}-N-(4- 1811 methylbenzyl)-lH-pyrazole-l-carboxamide N-(2-chlorobenzyl)-5-cyclobutyl-3- {2-hydroxy-5-[(4- 1812 methylbenzoyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclobutyl-N- (4-fluorobenzyl)-3- {2-hydroxy-5- [ (4- 1813 methylbenzoyl) amino phenyl}-lH-pyrazole-l-carboxamide 5-cyclobutyl-N- (3, 4-dichlorobenzyl)-3- {2-hydroxy-5- [ (4- 1814 methylbenzoyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {2-hydroxy-5-[(4-methylbenzoyl) amino] phenyl}-N-(4- 1815 methoxybenzyl)-1 H-pyrazole-1-carboxamide N- (sec-butyl)-5-cyclobutyl-3- {2-hydroxy-5- [ (4-methylbenzoyl) amino] phenyl}- 1816 IH-pyrazole-1-carboxamide 5-cyclobutyl-N-(2-fluorobenzyl)-3- {2-hydroxy-5-[(4- 1817 methylbenzoyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclobutyl-N- (3-fluorobenzyl)-3- {2-hydroxy-5- [ (4- 1818 methylbenzoyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclobutyl-N-cyclopropyl-3- {2-hydroxy-5- [ (4-methylbenzoyl) amino] phenyl}- 1819 lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {2-hydroxy-5- [ (4-methylbenzoyl) amino] phenyl}-N-isopropyl- 1820 1H-pyrazole-l-carboxamide 5-cyclopentyl-N-ethyl-3- {2-hydroxy-5- [ (4-methylbenzoyl) amino] phenyl}-lH- 1821 pyrazole-1-carboxamide N-allyl-5-cyclopentyl-3- {2-hydroxy-5- [ (4-methylbenzoyl) amino] phenyl}-lH- 1822 pyrazole-l-carboxamide 5-cyclopentyl-3-{2-hydroxy-5-[(4-methylbenzoyl) amino] phenyl}-N-propyl-lH- 1823 pyrazole-1-carboxamide N-benzyl-5-cyclopentyl-3- {2-hydroxy-5- [ (4-methylbenzoyl) amino] phenyl}-1H- 1824 pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-5- [ (4-methylbenzoyl) amino] phenyl}-N- (2- 1825 phenylethyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {2-hydroxy-5-[(4-methylbenzoyl) amino] phenyl}-N-(2- 1826 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {2-hydroxy-5- [ (4-methylbenzoyl) amino] phenyl}-N- (3- 1827 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- 2-hydroxy-5- [ (4-methylbenzoyl) amino] phenyl}-N- (4- 1828 methylbenzyl)-lH-pyrazole-l-carboxamide N- (2-chlorobenzyl)-5-cyclopentyl-3- {2-hydroxy-5- [ (4- 1829 methylbenzoyl) amino] phenyl}-1 H-pyrazole-1-carboxamide 5-cyclopentyl-N- (4-fluorobenzyl)-3- {2-hydroxy-5- [ (4- 1830 methylbenzoyl) amino] phenyl}-1 H-pyrazole-1-carboxarnide . $-cyclopentyl-N-(3, 4-dichlorobenzyl)-3- {2-hydroxy-5-[(4- 1831 methylbenzoyl) amino] phenyl}-1 H-pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-5-[(4-methylbenzoyl) amino] phenyl}-N-(4- 1832 methoxybenzyl)-1H-yrazole-1-carboxamide N- (sec-butyl)-5-cyclopentyl-3- {2-hydroxy-5- [ (4-methylbenzoyl) amino] phenyl}- 1833 1H-pyrazole-l-carboxamide 5-cyclopentyl-N-(2-fluorobenzyl)-3- {2-hydroxy-5-[(4- 1834 methylbenzoyl) amino] henyl}-1H-yrazole-1-carboxamide 5-cyclopentyl-N-(3-fluorobenzyl)-3- {2-hydroxy-5-[(4- 1835 methylbenzoyl) amino henyl}-lH-pyrazole-l-carboxamide ds. 5-cyclopentyl-N-cyclopropyl-3- {2-hydroxy-5- [ (4-methylbenzoyl) amino] phenyl}- 1836 IH-pyrazole-l-carboxamide 5-cyclopropyl-3- 5- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-isopropyl-lH- 1837 pyrazole-l-carboxamide 5-cyclopropyl-N-ethyl-3- {5-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-lH- 1838 pyrazole-l-carboxamide N-allyl-5-cyclopropyl-3- 5- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-1H- 1839 pyrazole-l-carboxamide 5-cyclopropyl-3- {5-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-propyl-lH- 1840 pyrazole-1-carboxamide N-benzyl-5-cyclopropyl-3- {3- [ (4-ethylbenzoyl) ammo]-2-hydroxyphenyl}-lH- 1841 pyrazole-l-carboxamide 5-cyclopropyl-3- {5-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-(2- 1842 phenylethyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {5-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-(2- 1843 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {5-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-(3- 1844 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3-45-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-(4- 1845 methylbenzyl)-lH-pyrazole-l-carboxamide N- (2-chlorobenzyl)-5-cyclopropyl-3- {5- [ (4-ethylbenzoyl) amino]-2- 1846 hydroxyphenyl}-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {5-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-(4- 1847 fluorobenzyl)-1 H-pyrazole-1-carboxamide 5-cyclopropyl-N- (3, 4-dichlorobenzyl)-3- {5- [ (4-ethylbenzoyl) amino]-2- 1848 hydroxyphenyl}-lH-pyrazole-l-carboxamide _ _ 5-cyclopropyl-3- {5- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N- (4- 1849 methoxybenzyl)-1H-pyrazole-1-carboxamide N- (sec-butyl)-5-cyclopropyl-3- {5- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-lH- 1850 pyrazole-l-carboxamide 5-cyclopropyl-3- {5- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N- (2- 1851 fluorobenzyl)-IH-pyrazole-l-carboxamide 5-cyclopropyl-3- {5- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N- (3- 1852 fluorobenzyl)-lH-pyrazole-l-carboxamide N, 5-dicyclopropyl-3- 5- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-lH-pyrazole- 1853 1-carboxamide 5-cyclobutyl-3-{5-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-isopropyl-lH- 1854 pyrazole-l-carboxamide .. 5-cyclobutyl-N-ethyl-3- {5-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-1H- 1855 yrazole-1-carboxamide N-allyl-5-cyclobutyl-3- {5-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-1H- 1856 pyrazole-1-carboxamide 5-cyclobutyl-3- {5- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-propyl-lH- 1857 pyrazole-l-carboxamide N-benzyl-5-cyclobutyl-3- {5- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-lH- 1858 pyrazole-l-carboxamide 5-cyclobutyl-3- {5- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-(2-phenylethyl)- 1859 1 H-pyrazole-1-carboxamide 5-cyclobutyl-3- {5-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-(2- 1860 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {5-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-(3- 1861 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {5-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-(4- 1862 methylbenzyl)-lH-pyrazole-l-carboxamide N- (2-chlorobenzyl)-5-cyclobutyl-3- {5- [ (4-ethylbenzoyl) amino]-2- 1863 hydroxyphenyl}-lH-pyrazole-l-carboxamide 5-cyclobutyl-3-{5-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-(4- 1864 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-N- (3, 4-dichlorobenzyl)-3- {5- [ (4-ethylbenzoyl) amino]-2- 1865 hydroxyphenyl}-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {5-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-(4- 1866 methoxybenzyl)-lH-pyrazole-l-carboxamide N- (sec-butyl)-5-cyclobutyl-3- {5- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-lH- 1867 pyrazole-l-carboxamide 5-cyclobutyl-3- {5-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-(2- 1868 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {5- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N- (3- 1869 fluorobenzyl)-IH-pyrazole-l-carboxamide 5-cyclobutyl-N-cyclopropyl-3- {5-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-1H- 1870 pyrazole-l-carboxamide 5-cyclopentyl-3- {5- [ (4-ethylbenzoyl) ammo]-2-hydroxyphenyl}-N-isopropyl-lH- 1871 pyrazole-l-carboxamide 5-cyclopentyl-N-ethyl-3- {5-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-1H- 1872 pyrazole-l-carboxamide N-allyl-5-cyclopentyl-3- {5- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-lH- 1873 pyrazole-l-carboxamide 5-cyclopentyl-3- {5-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-propyl-lH- 1874 pyrazole-l-carboxamide N-benzyl-5-cyclopentyl-3- {5-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-lH- 1875 pyrazole-l-carboxamide 5-cyclopentyl-3- {5-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-(2- 1876 phenylethyl)-1 H-pyrazole-1-carboxamide 5-cyclopentyl-3- {5- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N- (2- 1877 methylbenzyl)-IH-pyrazole-l-carboxamide 5-cyclopentyl-3- {5- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N- (3- 1878 methylbenzyl)-1 H-pyrazole-1-carboxamide 5-cyclopentyl-3- {5- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyll-N- (4- 1879 methylbenzyl)-lH-pyrazole-l-carboxamide N- (2-chlorobenzyl)-5-cyclopentyl-3- {5- [ (4-ethylbenzoyl) amino]-2- 1880 hydroxyphenyl}-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {5- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N- (4- 1881 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-N- (3, 4-dichlorobenzyl)-3- f 5- [ (4-ethylbenzoyl) amino]-2- 1882 hydroxyphenyl}-1H-pyrazole-1-carboxamide 5-cyclopentyl-3-f5- [ (4-ethylbenzoyl) ainino]-2-hydroxyphenyl}-N- (4- 1883 methoxybenzyl)-IH-pyrazole-l-carboxamide N- (sec-butyl)-5-cyclopentyl-3- {5- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-1H- 1884 pyrazole-l-carboxamide 5-cyclopentyl-3- {5-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N-(2- 1885 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- 5- [ (4-ethylbenzoyl) amino]-2-hydroxyphenyl}-N- (3- 1886 fluorobenzyl)-1H-yrazole-1-carboxamide 5-cyclopentyl-N-cyclopropyl-3- {5-[(4-ethylbenzoyl) amino]-2-hydroxyphenyl}- 1887 IH-yrazole-l-carboxamide 5-cyclopropyl-3- [2-hydroxy-5- (isobutyrylamino) phenyl]-N-isopropyl-lH- 1888 pyrazole-l-carboxamide y 5-cyclopropyl-N-ethyl-3- [2-hydroxy-5- (isobutyrylamino) phenyl]-lH-pyrazole-1- 1889 carboxamide N-allyl-5-cyclopropyl-3- [2-hydroxy-5- (isobutyrylamino) phenyl]-lH-pyrazole-l- 1890 carboxamide 5-cyclopropyl-3-[2-hydroxy-5-(isobutyrylamino) phenyl]-N-propyl-lH-pyrazole-l- 1891 carboxamide N-benzyl-5-cyclopropyl-3- [2-hydroxy-5- (isobutyrylamino) phenyl]-lH-pyrazole-l- 1892 carboxamide 5-cyclopropyl-3-[2-hydroxy-5-(isobutyrylamino) phenyl]-N-(2-phenylethyl)-lH- 1893 yrazole-1-carboxamide 5-cyclopropyl-3-[2-hydroxy-5-(isobutyrylamino) phenyl]-N-(2-methylbenzyl)-lH- 1894 pyrazole-1-carboxamide 5-cyclopropyl-3-[2-hydroxy-5-(isobutyrylamino) phenyl]-N-(3-methylbenzyl)-lH- 1895 pyrazole-l-carboxamide 5-cyclopropyl-3- [2-hydroxy-5- (isobutyrylamino) phenyl]-N- (4-methylbenzyl)-lH- 1896 pyrazole-I-carboxamide N- (2-chlorobenzyl)-5-cyclopropyl-3- [2-hydroxy-5- (isobutyrylamino) phenyl]-lH- 1897 pyrazole-l-carboxamide 5-cyclopropyl-N-(4-fluorobenzyl)-3-[2-hydroxy-5-(isobutyryla mino) phenyl]-1H- 1898 pyrazole-l-carboxamide A 5-cyclopropyl-N- (3, 4-dichlorobenzyl)-3- [2-hydroxy-5- (isobutyrylamino) phenyl]- 1899 1H-pyrazole-l-carboxamide 5-cyclopropyl-3- [2-hydroxy-5- (isobutyrylamino) phenyl]-N- (4-methoxybenzyl)- 1900 IH-pyrazole-l-carboxamide N-(sec-butyl)-5-cyclopropyl-3-[2-hydroxy-5-(isobutyrylamino) phenyl]-lH- 1901 pyrazole-1-carboxamide 5-cyclopropyl-N- (2-fluorobcnzyl)-3- [2-hydroxy-5- (isobutyrylamino) phenyl]-lH- 1902 pyrazole-l-carboxamide 5-cyclopropyl-N- (3-fluorobenzyl)-3- [2-hydroxy-5- (isobutyrylamino) phenyl]-lH- 1903 pyrazole-l-carboxamide X N, 5-dicyclopropyl-3-[2-hydroxy-5-(isobutyrylamino) phenyl]-lH-pyrazole-l- 1904 carboxamide 5-cyclobutyl-3- [2-hydroxy-5-(isobutyrylamino) phenyl]-N-isopropyl-1 H-pyrazole- 1905 1-carboxamide 5-cyclobutyl-N-ethyl-3- [2-hydroxy-5- (isobutyrylamino) phenyl]-lH-pyrazole-l- 1906 carboxamide N-allyl-5-cyclobutyl-3-[2-hydroxy-5-(isobutyrylamino) phenyl]-lH-pyrazole-l- 1907 carboxamide 5-cyclobutyl-3-[2-hydroxy-5-(isobutyrylamino) phenyl]-N-propyl-lH-pyrazole-l- 1908 carboxamide N-benzyl-5-cyclobutyl-3-[2-hydroxy-5-(isobutyrylamino) phenyl]-lH-pyrazole-l- 1909 carboxamide 5-cyclobutyl-3- [2-hydroxy-5-(isobutyrylarnino) phenyl]-N-(2-phenylethyl)-1 H- 1910 pyrazole-1-carboxamide 5-cyclobutyl-3- [2-hydroxy-5- (isobutyrylamino) phenyl]-N- (2-methylbenzyl)-lH- 1911 pyrazole-1-carboxamide 5-cyclobutyl-3- [2-hydroxy-5- (isobutyrylamino) phenyl]-N- (3-methylbenzyl)-lH- 1912 pyrazole-1-carboxamide 5-cyclobutyl-3- [2-hydroxy-5- (isobutyrylarnino) phenyl]-N- (4-methylbenzyl)-lH- 1913 yrazole-1-carboxamide N-(2-chlorobenzyl)-5-cyclobutyl-3-[2-hydroxy-5-(isobutyrylam ino) phenyl]-lH- 1914 pyrazole-1-carboxamide 5-cyclobutyl-N- (4-fluorobenzyl)-3- [2-hydroxy-5- (isobutyrylamino) phenyl]-1H- 1915 pyrazole-1-carboxamide 5-cyclobutyl-N- (3, 4-dichlorobenzyl)-3- [2-hydroxy-5- (isobutyrylamino) phenyl]- 1916 IH-pyrazole-1-carboxamide 5-cyclobutyl-3- [2-hydroxy-5- (isobutyrylamino) phenyl]-N- (4-methoxybenzyl)-lH- 1917 yrazole-1-carboxamide N-(sec-butyl)-5-cyclobutyl-3-[2-hydroxy-5-(isobutyrylamino) phenyl]-lH- 1918 pyrazole-1-carboxamide 5-cyclobutyl-N- (2-fluorobenzyl)-3- [2-hydroxy-5- (isobutyrylamino) phenyl]-lH- 1919 pyrazole-1-carboxamide A 5-cyclobutyl-N- (3-fluorobenzyl)-3- [2-hydroxy-5- (isobutyrylamino) phenyl]-lH- 1920 Dyrazole-1-carboxamide 5-cyclobutyl-N-cyclopropyl-3-[2-hydroxy-5-(isobutyrylamino) phenyl]-lH- 1921 pyrazole-1-carboxamide 5-cyclopentyl-3- [2-hydroxy-5- (isobutyrylamino) phenyl]-N-isopropyl-IH- 1922 pyrazole-1-carboxamide 5-cyclopentyl-N-ethyl-3- [2-hydroxy-5- (isobutyrylamino) phenyl]-lH-pyrazole-l- 1923 carboxamide N-allyl-5-cyclopentyl-3-[2-hydroxy-5-(isobutyrylamino) phenyl]-lH-pyrazole-l- 1924 carboxamide 5-cyclopentyl-3-[2-hydroxy-5-(isobutyrylamino) phenyl]-N-propyl-lH-pyrazole-l- 1925 carboxamide N-benzyl-5-cyclopentyl-3- [2-hydroxy-5- (isobutyrylamino) phenyl]-lH-pyrazole-l- 1926 carboxamide . S-cyclopentyl-3-[2-hydroxy-5-(isobutyrylamino) phenyl]-N-(2-phenylethyl)-lH- 1927 pyrazole-1-carboxamide 5-cyclopentyl-3- [2-hydroxy-5- (isobutyrylamino) phenyl]-N- (2-methylbenzyl)-1H- 1928 pyrazole-l-carboxamide 5-cyclopentyl-3- [2-hydroxy-5- (isobutyrylamino) phenyl]-N- (3-methylbenzyl)-lH- 1929 pyrazole-1-carboxamide 5-cyclopentyl-3- [2-hydroxy-5- (isobutyrylamino) phenyl]-N- (4-methylbenzyl)-lH- 1930 pyrazole-l-carboxamide N- (2-chlorobenzyl)-5-cyclopentyl-3- [2-hydroxy-5- (isobutyrylamino) phenyl]-lH- 1931 pyrazole-l-carboxamide A 5-cyclopentyl-N- (4-fluorobenzyl)-3- [2-hydroxy-5- (isobutyrylamino) phenyl]-lH- 1932 yrazole-1-carboxamide 5-cyclopentyl-N- (3, 4-dichlorobenzyl)-3- [2-hydroxy-5- (isobutyrylamino) phenyl]- 1933 IH-pyrazole-l-carboxamide 5-cyclopentyl-3- [2-hydroxy-5- (isobutyrylamino) phenyl]-N- (4-methoxybenzyl)- 1934 1H-pyrazole-l-carboxamide N-(sec-butyl)-5-cyclopentyl-3-[2-hydroxy-5-(isobutyrylamino) phenyl]-lH- 1935 pyrazole-1-carboxamide 5-cyclopentyl-N-(2-fluorobenzyl)-3-[2-hydroxy-5-(isobutyryla mino) phenyl]-1H- 1936 pyrazole-l-carboxamide 5-cyclopentyl-N- (3-fluorobenzyl)-3- [2-hydroxy-5- (isobutyrylamino) phenyl]-1H- 1937 Dyrazole-1-carboxainide 5-cyclopentyl-N-cyclopropyl-3-[2-hydroxy-5-(isobutyrylamino) phenyl]-1 H- 1938 pyrazole-1-carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclopropyl-N-isopropyl-1 H-pyrazole-1- 1939 carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclopropyl-N-ethyl-1H-pyra zole-1- 1940 carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-N-allyl-5-cyclopropyl-lH-pyra zole-l- 1941 carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclopropyl-N-propyl-lH-pyr azole-l- 1942 carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-N-benzyl-5-cyclopropyl-1 H-pyrazole-1- 1943 carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclopropyl-N- (2-phenylethyl)-lH- 1944 pyrazole-l-carboxamide 3-E5- (acetylamino)-2-hydroxyphenyl]-5-cyclopropyl-N- (2-methylbenzyl)-IH- 1945 pyrazole-1-carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclopropyl-N- (3-methylbenzyl)-lH- 1946 pyrazole-1-carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclopropyl-N- (4-methylbenzyl)-lH- 1947 pyrazole-l-carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-N- (2-chlorobenzyl)-5-cyclopropyl-1 H- 1948 yrazole-1-carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclopropyl-N- (4-fluorobenzyl)-lH- 1949 yrazole-1-carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclopropyl-N- (3, 4-dichlorobenzyl)-1H- 1950 pyrazole-l-carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclopropyl-N- (4-methoxybenzyl)-1H- 1951 pyrazole-1-carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-N- (sec-butyl)-5-cyclopropyl-lH-pyrazole-l- 1952 carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclopropyl-N- (2-fluorobenzyl)-1 H- 1953 pyrazole-1-carboxamide a 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclopropyl-N- (3-fluorobenzyl)-1 H- 1954 pyrazole-l-carboxamide z 3- [5- (acetylamino)-2-hydroxyphenyl]-N, 5-dicyclopropyl-lH-pyrazole-l- 1955 carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclobutyl-N-isopropyl-lH-p yrazole-l- 1956 carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclobutyl-N-ethyl-lH-pyraz ole-l- 1957 carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-N-allyl-5-cyclobutyl-1 H-pyrazole-1- 1958 carboxamide 3- [5- (acetylaxnino)-2-hydroxyphenyl]-5-cyclobutyl-N-propyl-lH-pyr azole-l- 1959 carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-N-benzyl-5-cyclobutyl-lH-pyra zole-l- 1960 carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclobutyl-N- (2-phenylethyl)-lH- 1961 pyrazole-l-carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclobutyl-N- (2-methylbenzyl)-lH- 1962 pyrazole-l-carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclobutyl-N- (3-methylbenzyl)-lH- 1963 pyrazole-l-carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclobutyl-N- (4-methylbenzyl)-1H- 1964 pyrazole-l-carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-N- (2-chlorobenzyl)-5-cyclobutyl-lH- 1965 pyrazole-l-carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclobutyl-N- (4-fluorobenzyl)-1H- 1966 pyrazole-l-carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclobutyl-N- (3, 4-dichlorobenzyl)-lH- 1967 pyrazole-1-carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclobutyl-N- (4-methoxybenzyl)-lH- 1968 yrazole-1-carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-N- (sec-butyl)-5-cyclobutyl-lH-pyrazole-l- 1969 carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclobutyl-N- (2-fluorobenzyl)-lH- 1970 pyrazole-l-carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclobutyl-N- (3-fluorobenzyl)-1 H- 1971 pyrazole-l-carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclobutyl-N-cyclopropyl-lH -pyrazole-1- 1972 carboxamide 3- [5- (acetylarnino)-2-hydroxyphenyl]-5-cyclopentyl-N-isopropyl-lH -pyrazole-1- 1973 carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclopentyl-N-ethyl-lH-pyra zole-l- 1974 carboxamide 3- [5- H-pyrazole-1- 1975 carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclopentyl-N-propyl-lH-pyr azole-l- 1976 carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-N-benzyl-5-cyclopentyl-lH-pyr azole-l- 1977 carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclopentyl-N- (2-phenylethyl)-lH- 1978 pyrazole-1-carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclopentyl-N- (2-methylbenzyl)-lH- 1979 pyrazole-l-carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclopentyl-N- (3-methylbenzyl)-IH- 1980 pyrazole-1-carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclopentyl-N- (4-methylbenzyl)-1H- 1981 yrazole-1-carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-N- (2-chlorobenzyl)-5-cyclopentyl-lH- 1982 yrazole-1-carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclopentyl-N- (4-fluorobenzyl)-lH- 1983 pyrazole-l-carboxamide A 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclopentyl-N- (3, 4-dichlorobenzyl)-lH- 1984 pyrazole-l-carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclopentyl-N- (4-methoxybenzyl)-lH- 1985 pyrazole-l-carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-N- (sec-butyl)-5-cyclopentyl-lH-pyrazole-l- 1986 carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclopentyl-N- (2-fluorobenzyl)-lH- 1987 pyrazole-1-carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclopentyl-N- (3-fluorobenzyl)-1H- 1988 pyrazole-l-carboxamide 3- [5- (acetylamino)-2-hydroxyphenyl]-5-cyclopentyl-N-cyclopropyl-l H-pyrazole- 1989 1-carboxamide 5-cyclopropyl-3- {2-hydroxy-5-[(3-methylbutanoyl) amino] phenyl}-N-isopropyl- 1990 1H-pyrazole-l-carboxamide 5-cyclopropyl-N-ethyl-3-{2-hydroxy-5-[(3-methylbutanoyl) amino] phenyl}-1H- 1991 pyrazole-l-carboxamide N-allyl-5-cyclopropyl-3- {2-hydroxy-5-[(3-methylbutanoyl) amino] phenyl}-lH- 1992 pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-5- [ (3-methylbutanoyl) amino] phenyl}-N-propyl-1 H- 1993 yrazole-1-carboxamide A N-benzyl-5-cyclopropyl-3- {2-hydroxy-5- [ (3-methylbutanoyl) amino] phenyl}-1 H- 1994 pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-5- [ (3-methylbutanoyl) amino] phenyl}-N- (2- 1995 phenylethyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {2-hydroxy-5-[(3-methylbutalloyl) amino] phenyl}-N-(2- 1996 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {2-hydroxy-5- [ (3-methylbutanoyl) amino] phenyl}-N- (3- 1997 methylbenzyl)-lH-pyrazole-1-carboxarnide 5-cyclopropyl-3- {2-hydroxy-5- [ (3-methylbutanoyl) amino] phenyl}-N- (4- 1998 methylbenzyl)-IH-pyrazole-1-carboxamide N- (2-chlorobenzyl)-S-cyclopropyl-3- f 2-hydroxy-5- (3-, 1999 methylbutanoyl) aminolphenyl-lH-pyrazole-l-carboxamide 5-cyclopropyl-N- (4-fluorobenzyl)-3- {2-hydroxy-5- [ (3- 2000 methylbutanoyl) amino phenyl-lH-pyrazole-l-carboxamide 5-cyclopropyl-N- (3, 4-dichlorobenzyl)-3- {2-hydroxy-5- [ (3- 2001 methylbutanoyl) amino phenyl-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {2-hydroxy-5- [ (3-methylbutanoyl) amino] phenyl}-N- (4- 2002 methoxybenzyl)-lH-pyrazole-1-carboxamide N- (sec-butyl)-5-cyclopropyl-3- {2-hydroxy-5- [ (3-methylbutanoyl) amino] phenyl}- 2003 1H-yrazole-1-carboxamide 5-cyclopropyl-N- (2-fluorobenzyl)-3- {2-hydroxy-5- [ (3- 2004 methylbutanoyl) aminolDhenyl}-lH-Pyrazole-l-carboxamide 5-cyclopropyl-N- (3-fluorobenzyl)-3- {2-hydroxy-5- [ (3- 2005 methylbutanoyl) amino] phenyl}-IH-pyrazole-l-carboxamide N, 5-dicyclopropyl-3- {2-hydroxy-5-[(3-methylbutanoyl) amino] phenyl}-1H- 2006 pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-5- [ (3-methylbutanoyl) amino] phenyl}-N-isopropyl-IH- 2007 pyrazole-1-carboxamide 5-cyclobutyl-N-ethyl-3- {2-hydroxy-5- [ (3-methylbutanoyl) amino] phenyl}-lH- 2008 pyrazole-1-carboxamide N-allyl-5-cyclobutyl-3- {2-hydroxy-5- [ (3-methylbutanoyl) amino] phenyl}-IH- 2009 pyrazole-1-carboxamide 5-cyclobutyl-3- 2-hydroxy-5- [ (3-methylbutanoyl) amino] phenyl}-N-propyl-lH- 2010 pyrazole-1-carboxamide N-benzyl-5-cyclobutyl-3- {2-hydroxy-5-[(3-methylbutanoyl) amino] phenyl}-1H- 2011 pyrazole-l-carboxamide 5-cyclobutyl-3- {2-hydroxy-5- [ (3-methylbutanoyl) amino] phenyl}-N- (2- 2012 phenylethyl)-IH-pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-5- [ (3-methylbutanoyl) amino] phenyl}-N- (2- 2013 methylbenzyl)-lH-pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-5- [ (3-methylbutanoyl) ammo] phenyl}-N- (3- 2014 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {2-hydroxy-5- [ (3-methylbutanoyl) amino] phenyl}-N- (4- 2015 methylbenzyl)-lH-pyrazole-l-carboxamide N- (2-chlorobenzyl)-5-cyclobutyl-3-f2-hydroxy-5- [ (3- 2016 methylbutanoyl) amino] phenyl-lH-pyrazole-l-carboxamide 5-cyclobutyl-N- (4-fluorobenzyl)-3- {2-hydroxy-5- [ (3- 2017 methylbutanoyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclobutyl-N- (3, 4-dichlorobenzyl)-3- {2-hydroxy-5- [ (3- 2018 methylbutanoyl) amino henyl}-1H-pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-5- [ (3-methylbutanoyl) amino] phenyl}-N- (4- 2019 methoxybenzyl)-1H-yrazole-1-carboxamide A N- (sec-butyl)-5-cyclobutyl-3- {2-hydroxy-5- [ (3-methylbutanoyl) amino] phenyl}- 2020 1H-yrazole-1-carboxamide s 5-cyclobutyl-N- (2-fluorobenzyl)-3- {2-hydroxy-5- [ (3- 2021 methylbutanoyl) amino] henyl-lH-pyrazole-l-carboxamide 5-cyclobutyl-N- (3-fluorobenzyl)-3- {2-hydroxy-5- [ (3- 2022 methylbutanoyl) amino] henyl}-1H-yrazole-1-carboxamide A 5-cyclobutyl-N-cyclopropyl-3- {2-hydroxy-5-[(3-methylbutanoyl) amino] phenyl}- 2023 lH-syrazole-l-carboxamide A 5-cyclopentyl-3- {2-hydroxy-5-[(3-methylbutanoyl) amino] phenyl3-N-isopropyl- 2024 IH-pyrazole-l-carboxamide s 5-cyclopentyl-N-ethyl-3- {2-hydroxy-5-[(3-methylbutanoyl) amino] phenyl}-1H- 2025 pyrazole-1-carboxamide s N-allyl-5-cyclopentyl-3- {2-hydroxy-5- [ (3-methylbutanoyl) amino] phenyl}-1H- 2026 yrazole-X-carboxamide A 5-cyclopentyl-3- {2-hydroxy-5-[(3-methylbutanoyl) amino] phenyl}-N-propyl-lH- 2027 pyrazole-1-carboxamide N-benzyl-5-cyclopentyl-3- {2-hydroxy-5-[(3-methylbutanoyl) amino] phenyl}-lH- 2028 pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-5-[(3-methylbutanoyl) amino] phenyl}-N-(2- 2029 henylethyl)-1H-yrazole-l-carboxamide 5-cyclopentyl-3- {2-hydroxy-5-[(3-methylbutanoyl) amino] phenyl}-N-(2- 2030 methylbenzyl)-1 H-pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-5-[(3-methylbutanoyl) amino] phenyl}-N-(3- 2031 methylbenzyl)-1 H-pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-5-[(3-methylbutanoyl) amino] phenyl}-N-(4- 2032 methylbenzyl)-lH-pyrazole-l-carboxamide N- (2-chlorobenzyl)-5-cyclopentyl-3- {2-hydroxy-5- [ (3- 2033 methylbutanoyl) amino] phenyl-lH-pyrazole-l-carboxamide 5-cyclopentyl-N- (4-fluorobenzyl)-3- {2-hydroxy-5- [ (3- 2034 methylbutanoyl) amino henyl-lH-pyrazole-1-carboxamide 5-cyclopentyl-N- (3, 4-dichlorobenzyl)-3- {2-hydroxy-5- [ (3- 2035 methylbutanoyl) amino] phenyl-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {2-hydroxy-5- [ (3-methylbutanoyl) amino] phenyl}-N- (4- 2036 methoxybenzyl)-lH-pyrazole-l-carboxamide N- (sec-butyl)-5-cyclopentyl-3- 2-hydroxy-5- [ (3-methylbutanoyl) amino] phenyl}- 2037 lH-nyrazole-1-carboxamide A 5-cyclopentyl-N- (2-fluorobenzyl)-3- {2-hydroxy-5- [ (3- 2038 methylbutanoyl) amino] phenyl-IH-pyrazole-1-carboxamide 5-cyclopentyl-N-(3-fluorobenzyl)-3- {2-hydroxy-5-[(3- 2039 methylbutanoyl) amino henyl-lH-pyrazole-I-carboxamide 5-cyclopentyl-N-cyclopropyl-3- {2-hydroxy-5-[(3-methylbutanoyl) arnino] phenyl}- 2040 1H-yrazole-1-carboxamide 5-cyclopropyl-3-[2-hydroxy-5-(propionylamino) phenyl]-N-isopropyl-lH- 2041 pyrazole-l-carboxamide s 5-cyclopropyl-N-ethyl-3-[2-hydroxy-5-(propionylamino) phenyl]-lH-pyrazole-l- 2042 carboxamide N-allyl-5-cyclopropyl-3-[2-hydroxy-5-(propionylamino) phenyl]-lH-pyrazole-l- 2043 carboxamide 5-cyclopropyl-3-[2-hydroxy-5-(propionylamino) phenyl]-N-propyl-lH-pyrazole-l- 2044 carboxamide N-benzyl-5-cyclopropyl-3- [2-hydroxy-5- (propionylamino) phenyl]- IH-pyrazole-I- 2045 carboxamide 5-cyclopropyl-3- [2-hydroxy-5- (propionylamino) phenyl]-N- (2-phenylethyl)-1H- 2046 pyrazole-1-carboxamide 5-cyclopropyl-3- [2-hydroxy-5- (propionylamino) phenyl]-N- (2-methylbenzyl)-lH- 2047 pyrazole-I-carboxamide 5-cyclopropyl-3-[2-hydroxy-5-(propionylamino) phenyl]-N-(3-methylbenzyl)-lH- 2048 pyrazole-1-carboxamide 5-cyclopropyl-3- [2-hydroxy-5- (propionylamino) phenyl]-N- (4-methylbenzyl)-lH- 2049 pyrazole-1-carboxamide N- (2-chlorobenzyl)-5-cyclopropyl-3- [2-hydroxy-5- (propionylamino) phenyl]-lH- 2050 pyrazole-I-carboxamide 5-cyclopropyl-N- (4-fluorobenzyl)-3- [2-hydroxy-5- (propionylamino) phenyl]-lH- 2051 pyrazole-1-carboxamide 5-cyclopropyl-N- (3, 4-dichlorobenzyl)-3- [2-hydroxy-5- (propionylamino) phenyl]- 2052 1 H-pyrazole-1-carboxamide 5-cyclopropyl-3- [2-hydroxy-5- (propionylamino) phenyl]-N- (4-methoxybenzyl)- 2053 1H-yrazole-1-carboxamide x N- (sec-butyl)-5-cyclopropyl-3- [2-hydroxy-5- (propionylamino) phenyl]-lH- 2054 pyrazole-1-carboxamide s 5-cyclopropyl-N-(2-fluorobenzyl)-3-[2-hydroxy-5-(propionylam ino) phenyl]-lH- 2055 pyrazole-1-carboxamide a 5-cyclopropyl-N- (3-fluorobenzyl)-3- [2-hydroxy-5- (propionylamino) phenyl]-lH- 2056 pyrazole-1-carboxamide A N, 5-dicyclopropyl-3-[2-hydroxy-5-(propionylamino) phenyl]-lH-pyrazole-l- 2057 carboxamide 5-cyclobutyl-3-[2-hydroxy-5-(propionylamino) phenyl]-N-isopropyl-1 H-pyrazole- 2058 1-carboxamide 5-cyclobutyl-N-ethyl-3-[2-hydroxy-5-(propionylamino) phenyl3-lH-pyrazole-1- 2059 carboxamide N-allyl-5-cyclobutyl-3- [2-hydroxy-5- (propionylamino) phenyl]-lH-pyrazole-l- 2060 carboxamide 5-cyclobuty1-3-[2-hydroxy-5-(propionylamino) phenyl]-N-propyl-lH-pyrazole-1- 2061 carboxamide N-benzyl-5-cyclobutyl-3-[2-hydroxy-5-(propionylamino) phenyl]-lH-pyrazole-l- 2062 carboxamide 5-cyclobutyl-3-[2-hydroxy-5-(propionylamino) phenyl]-N-(2-phenylethyl)-lH- 2063 pyrazole-1-carboxaxnide 5-cyclobutyl-3- [2-hydroxy-5- (propionylamino) phenyl]-N- (2-methylbenzyl)-1 H- 2064 pyrazole-1-carboxamide 5-cyclobutyl-3- [2-hydroxy-5- (propionylamino) phenyl]-N- (3-methylbenzyl)-lH- 2065 yrazole-1-carboxamide 5-cyclobutyl-3- [2-hydroxy-5- (propionylamino) phenyl]-N- (4-methylbenzyl)-lH- 2066 pyrazole-1-carboxamide N-(2-chlorobenzyl)-5-cyclobutyl-3-[2-hydroxy-5-(propionylami no) phenyl]-lH- 2067 pyrazole-1-carboxamide 5-cyclobutyl-N- (4-fluorobenzyl)-3- [2-hydroxy-5- (propionylamino) phenyl]-lH- 2068 pyrazole-I-carboxamide 5-cyclobutyl-N- (3, 4-dichlorobenzyl)-3- [2-hydroxy-5- (propionylamino) phenyl]- 2069 IH-pyrazole-l-carboxamide 5-cyclobutyl-3- [2-hydroxy-5- (propionylamino) phenyl]-N- (4-methoxybenzyl)-lH- 2070 pyrazole-l-carboxamide . N-(sec-butyl)-5-cyclobutyl-3-[2-hydroxy-5-(propionylamino) phenyl]-1H- 2071 pyrazole-1-carboxamide 5-cyclobutyl-N- (2-fluorobenzyl)-3- [2-hydroxy-5- (propionylamino) phenyl]-lH- 2072 pyrazole-l-carboxamide 5-cyclobutyl-N-(3-fluorobenzyl)-3-[2-hydroxy-5-(propionylami no) phenyl]-lH- 2073 pyrazole-1-carboxamide 5-cyclobutyl-N-cyclopropyl-3-[2-hydroxy-5-(propionylamino) phenyl]-1H- 2074 pyrazole-1-carboxamide 5-cyclopentyl-3-[2-hydroxy-5-(propionylamino) phenyl]-N-isopropyl-ltI-pyrazole- 2075 1-carboxamide 5-cyclopentyl-N-ethyl-3-[2-hydroxy-5-(propionylamino) phenyl]-lH-pyrazole-l- 2076 carboxamide N-allyl-5-cyclopentyl-3- [2-hydroxy-5- (propionylamino) phenyl]-1H-pyrazole-l- 2077 carboxamide 5-cyclopentyl-3- [2-hydroxy-5- (propionylamino) phenyl]-N-propyl-lH-pyrazole-l- 2078 carboxamide N-benzyl-5-cyclopentyl-3-[2-hydroxy-5-(propionylamino) phenyl]-lH-pyrazole-l- 2079 carboxamide 5-cyclopentyl-3- [2-hydroxy-5- (propionylamino) phenyl]-N- (2-phenylethyl)-lH- 2080 Pyrazole-l-carboxamide 5-cyclopentyl-3-[2-hydroxy-5-(propionylamino) phenyl]-N-(2-methylbenzyl)-lH- pyrazole-l-carboxamide 5-cyclopentyl-3- [2-hydroxy-5- (propionylamino) phenyl]-N- (3-methylbenzyl)-lH- 2082 pyrazole-l-carboxamide 5-cyclopentyl-3- [2-hydroxy-5- (propionylamino) phenyl]-N- (4-methylbenzyl)-lH- 2083 yrazole-1-carboxamide N- (2-chlorobenzyl)-5-cyclopentyl-3- [2-hydroxy-5- (propionylamino) phenyl]-lH- 2084 pyrazole-1-carboxamide 5-cyclopentyl-N- (4-fluorobenzyl)-3- [2-hydroxy-5- (propionylamino) phenyl]-lH- 2085 pyrazole-1-carboxamide 5-cyclopentyl-N- (3, 4-dichlorobenzyl)-3- [2-hydroxy-5- (propionylamino) phenyl]- 2086 1H-pyrazole-1-carboxamide 5-cyclopentyl-3- [2-hydroxy-5- (propionylamino) phenyl]-N- (4-methoxybenzyl)- 2087 IH-pyrazole-l-carboxamide N- (sec-butyl)-5-cyclopentyl-3- [2-hydroxy-5- (propionylamino) phenyl]-lH- 2088 pyrazole-l-carboxamide 5-cyclopentyl-N- (2-fluorobenzyl)-3- [2-hydroxy-5- (propionylamino) phenyl]-lH- 2089 pyrazole-I-carboxamide 5-cyclopentyl-N- (3-fluorobenzyl)-3- [2-hydroxy-5- (propionylamino) phenyl]-lH- 2090 yrazole-1-carboxamide 5-cyclopentyl-N-cyclopropyl-3- [2-hydroxy-5- (propionylamino) phenyl]-lH- 2091 pyrazole-l-carboxainide 5-cyclopropyl-3- {5-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N- 2092 isopropyl-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {5- [(cyclopropylcarbonyl) aInino]-2-hydroxyphenyl}-N-ethyl-1 H- 2093 pyrazole-1-carboxamide N-allyl-5-cyclopropyl-3- {5-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-1H- 2094 pyrazole-1-carboxamide 5-cyclopropyl-3- {5-[(cyelopropylcarbonyl) amino]-2-hydroxyphenyl}-N-propyl- 2095 IH-pyrazole-l-carboxamide N-benzyl-5-eyclopropyl-3- {5-[(eyelopropylcarbonyl) arnino]-2-hydroxyphenyl}- 2096 1H-yrazole-1-carboxamide 5-cyclopropyl-3- {5-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-(2- 2097 phenylethyl)-IH-pyrazole-l-carboxatnide 5-cyclopropyl-3- {5- [ (cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N- (2- 2098 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {5- [ (cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N- (3- 2099 methylbenzyl)-IH-pyrazole-1-carboxamide 5-cyclopropyl-3- {5-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-(4- 2100 methylbenzyl)-1 H-pyrazole-1-carboxamide N-(2-chlorobenzyl)-5-cyclopropyl-3- {5-[(cyelopropylearbonyl) amino]-2- 2101 hydroxyphenyl}-lH-pyrazole-l-carboxamide 5-cyclopropyl-3-f {5- [ (cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N- (4- 2102 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {5- [ (cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N- (3, 4- 2103 dichlorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {5- [ (cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N- (4- 2104 methoxybenzyl)-IH-pyrazole-1-carboxamide N-(see-butyl)-5-cyclopropyl-3- {5-[(cyelopropylearbonyl) amino]-2- 2105 hydroxyphenyl-IH-pyrazole-1-carboxarnide 5-cyclopropyl-3-{5-[(cyclopropylcarbonyl) aTnino]-2-hydroxyphenyl}-N-(2- 2106 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {5- [ (cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N- (3- 2107 fluorobenzyl)-lH-pyrazole-l-carboxamide N, 5-dicyclopropyl-3- {5- [ (cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-lH- 2108 pyrazole-I-carboxamide x 5-cyclobutyl-3- {5- [ (cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-isopropyl- 2109 I-carboxamide 5-cyclobutyl-3- {5- [ (cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-ethyl-1H- 2110 pyrazole-l-carboxamide N-allyl-5-cyclobutyl-3- {5- [ (cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-1H- 2111 yrazole-1-carboxamide 5-cyclobutyl-3- {5-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-propyl-lH- 2112 pyrazole-l-carboxamide N-benzyl-5-cyclobutyl-3- {5-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-1H- 2113 pyrazole-1-carboxamide 5-cyclobutyl-3- {5-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-(2- 2114 phenylethyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- 5- [ (cyclopropylcarbonyl) amino]-2-hydroxyphenyl)-N- (2- 2115 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {5- [ (cyclopropylc arbonyl) amino]-2-hydroxyphenyl}-N- (3- 2116 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {5- [ (cyclopropylcarbonyl) ammo]-2-hydroxyphenyl}-N- (4- 2117 methylbenzyl)-1H-pyrazole-1-carboxamide N- (2-chlorobenzyl)-5-cyclobutyl-3-15- [ (cyclopropylearbonyl) amino]-2- 2118 hydroxyphenyl}-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {5-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-(4-. 2119 fluorobenzyl)-1 H-pyrazole-1-carboxamide 5-cyclobutyl-3- 5- [ (cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N- (3, 4- 2120 dichlorobenzyl)-lH-pyrazole-l-carboxarnide 5-cyclobutyl-3- {5-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-(4- 2121 methoxybenzyl)-1 H-pyrazole-1-carboxamide N- (sec-butyl)-5-cyclobutyl-3- {5- [ (cyclopropylcarbonyl) amino]-2- 2122 hydroxyphenyl}-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {5- [ (cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N- (2- 2123 fluorobenzyl)-1H-pyrazole-1-carboxamide 5-cyclobutyl-3- {5- [ (cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N- (3- 2124 fluorobenzyl)-IH-pyrazole-1-carboxamide 5-cyclobutyl-N-cyclopropyl-3- {5-[(cyclopropylcarbonyl) alnino]-2- 2125 hydroxyphenyl}-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {5-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-isopropyl- 2126 IH-pyrazole-1-carboxamide 5-cyclopentyl-3- {5-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-ethyl-lH- 2127 pyrazole-1-carboxamide N-allyl-5-cyclopentyl-3- {5- [ (cyclopropylcarbonyl) ammo]-2-hydroxyphenyl}-lH- 2128 pyrazole-1-carboxamide 5-cyclopentyl-3- 5- [ (cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-propyl- 2129 1H-yrazole-1-carboxamide N-benzyl-5-cyclopentyl-3- {5-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}- 2130 IH-pyrazole-l-carboxamide 5-cyclopentyl-3- {5-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-(2- phenylethyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {5-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-(2- 2132 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {5-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-(3- 2133 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {5-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-(4- 2134 methylbenzyl)-IH-pyrazole-1-carboxamide N-(2-chlorobenzyl)-5-cyclopentyl-3- {5-[(cyclopropylcarbonyl) amino]-2- 2135 hydroxyphenyl}-1H-pyrazole-I-carboxamide 5-cyclopentyl-3- {5-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-(4- 2136 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {5- [(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-(3, 4- 2137 dichlorobenzyl)-1H-pyrazole-1-carboxamide 5-cyclopentyl-3- {5-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-(4- 2138 methoxybenzyl)-lH-pyrazole-l-carboxamide N- (sec-butyl)-5-cyclopentyl-3- {5- [ (cyclopropylcarbonyl) amino]-2- 2139 hydroxyphenyl}-1 H-pyrazole-1-carboxamide 5-cyclopentyl-3- {5-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-(2- 2140 fluorobenzyl)-1 H-pyrazole-1-carboxamide A 5-cyclopentyl-3- {5-[(cyclopropylcarbonyl) amino]-2-hydroxyphenyl}-N-(3- 2141 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-N-cyclopropyl-3- {5- [ (cyclopropylcarbonyl) ammo]-2- 2142 hydroxyphenyl-1 H-pyrazole-1-carboxamide 1 5-cyclopropyl-3- [5- H-pyrazole- 2143 1-carboxamide 5-cyclopropyl-N-ethyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-lH-pyrazole-l- 2144 carboxamide N-allyl-5-cyclopropyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-1H-pyrazole-1- 2145 carboxamide 5-cyclopropyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-N-propyl-1 H-pyrazole-1- 2146 carboxamide N-benzyl-5-cyclopropyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-1H-pyrazole-1- 2147 carboxamide 5-cyclopropyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-N- (2-phenylethyl)-IH- 2148 pyrazole-1-carboxamide A 5-cyclopropyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-N- (2-methylbenzyl)-lH- 2149 pyrazole-1-carboxamide 5-cyclopropyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-N- (3-methylbenzyl)-1 H- 2150 pyrazole-1-carboxamide 5-cyclopropyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-N- (4-methylbenzyl)-lH- 2151 pyrazole-l-carboxamide N- (2-chlorobenzyl)-5-cyclopropyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-lH- 2152 pyrazole-1-carboxamide 5-cyclopropyl-N- (4-fluorobenzyl)-3- [5- (2-furoylamino)-2-hydroxyphenyl]-lH- 2153 pyrazole-1-carboxamide 5-cyclopropyl-N- (3, 4-dichlorobenzyl)-3- [5- (2-furoylamino)-2-hydroxyphenyl]- 2154 1H-pyrazole-l-carboxamide 5-cyclopropyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-N- (4-methoxybenzyl)-lH- 2155 yrazole-I-carboxamide N- (sec-butyl)-5-cyclopropyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-lH-pyrazole- 2156 1-carboxamide 2156 1-carboxamide 5-cyclopropyl-N- (2-fluorobenzyl)-3- [5- (2-furoylamino)-2-hydroxyphenyl]-lH- 2157 jpyrazole-1-carboxamide 5-cyclopropyl-N- (3-fluorobenzyl)-3- 5- (2-furoylamino)-2-hydroxyphenyl]-lH- 2158 pyrazole-l-carboxamide N, 5-dicyclopropyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-1H-pyrazole-l- 2159 carboxamide 5-cyclobutyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-N-isopropyl-lH-pyrazole-l- 2160 carboxamide 5-cyclobutyl-N-ethyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-lH-pyrazole-l- 2161 carboxamide N-allyl-5-cyclobutyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-1 H-pyrazole-1- 2162 carboxamide 5-cyclobutyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-N-propyl-lH-pyrazole-l- 2163 carboxamide N-benzyl-5-cyclobutyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-1 H-pyrazole-1- 2164 carboxamide 5-cyclobutyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-N- (2-phenylethyl)-lH- 2165 pyrazole-l-carboxamide 5-cyclobutyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-N- (2-methylbenzyl)-lH- 2166 pyrazole-1-carboxamide 5-cyclobutyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-N- (3-methylbenzyl)-lH- 2167 pyrazole-l-carboxamide 5-cyclobutyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-N- (4-methylbenzyl)-lH- 2168 yrazole-1-carboxamide N- (2-chlorobenzyl)-5-cyclobutyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-lH- 2169 pyrazole-1-carboxamide 5-cyclobutyl-N- (4-fluorobenzyl)-3- [5- (2-furoylamino)-2-hydroxyphenyl]-lH- 2170 pyrazole-l-carboxamide 5-cyclobutyl-N- (3, 4-dichlorobenzyl)-3- [5- (2-furoylamino)-2-hydroxyphenyl]-lH- 2171 pyrazole-1-carboxamide 5-cyclobutyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-N- (4-methoxybenzyl)-1 H- 2172 pyrazole-1-carboxamide N- (sec-butyl)-5-cyclobutyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-lH-pyrazole- 2173 1-carboxamide 5-cyclobutyl-N- (2-fluorobenzyl)-3- [5- (2-furoylamino)-2-hydroxyphenyl]-1 H- 2174 pyrazole-1-carboxamide 5-cyclobutyl-N- (3-fluorobenzyl)-3- [5- (2-furoylamino)-2-hydroxyphenyl]-lH- 2175 pyrazole-l-carboxamide 5-cyclobutyl-N-cyclopropyl-3- [5- (2-furoylarnino)-2-hydroxyphenyl]-lH-pyrazole- 2176 1-carboxamide 5-cyclopentyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-N-isopropyl-lH-pyrazole- 2177 1-carboxamide 5-cyclopentyl-N-ethyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-lH-pyrazole-l- 2178 carboxamide N-allyl-5-cyclopentyl-3- [5-(2-furoylamino)-2-hydroxyphenyl]-1 H-pyrazole-1- 2179 carboxamide 5-cyclopentyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-N-propyl-lH-pyrazole-l- 2180 carboxamide N-benzyl-5-cyclopentyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-lH-pyrazole-l- 2181 carboxamide 5-cyclopentyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-N- (2-phenylethyl)-lH- 2182 pyrazole-1-carboxamide 5-cyclopentyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-N- (2-methylbenzyl)-lH- 2183 yrazole-1-carboxamide 5-cyclopentyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-N- (3-methylbenzyl)-lH- 2184 pyrazole-1-carboxamide 5-cyclopentyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-N- (4-methylbenzyl)-lH- 2185 pyrazole-1-carboxamide N- (2-chlorobenzyl)-5-cyclopentyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-lH- 2186 pyrazole-1-carboxamide 5-cyclopentyl-N- (4-fluorobenzyl)-3- [5- (2-furoylamino)-2-hydroxyphenyl]-lH- 2187 pyrazole-1-carboxamide 5-cyclopentyl-N- (3, 4-dichlorobenzyl)-3- [5- (2-furoylamino)-2-hydroxyphenyl]- 2188 IH-pyrazole-l-carboxamide 5-cyclopentyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-N- (4-methoxybenzyl)-lH- 2189 pyrazole-1-carboxamide N- (sec-butyl)-5-cyclopentyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-lH-pyrazole- 2190 1-carboxamide 5-cyclopentyl-N- (2-fluorobenzyl)-3- [5- (2-furoylamino)-2-hydroxyphenyl]-lH- 2191 pyrazole-l-carboxamide 5-cyclopentyl-N- (3-fluorobenzyl)-3- [5- (2-furoylamino)-2-hydroxyphenyl]-lH- 2192 pyrazole-1-carboxamide 5-cyclopentyl-N-cyclopropyl-3- [5- (2-furoylamino)-2-hydroxyphenyl]-lH- 2193 pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-5-[(thien-2-ylcarbonyl) arnino] phenyl}-N-isopropyl- 2194 IH-pyrazole-l-carboxamide 5-cyclopropyl-N-ethyl-3- {2-hydroxy-5-[(thien-2-ylcarbonyl) amino] phenyl}-1H- 2195 yrazole-1-carboxamide N-allyl-5-cyclopropyl-3- {2-hydroxy-5-[(thien-2-ylcarbonyl) amino] phenyl}-1H- 2196 pyrazole-l-carboxamide 5-cyclopropyl-3- {2-hydroxy-5-[(thien-2-ylcarbonyl) amino] phenyl}-N-propyl-llI- 2197 pyrazole-1-carboxamide N-benzyl-5-cyclopropyl-3- {2-hydroxy-5- [ (thien-2-ylcarbonyl) amino] phenyl}-1H- 2198 yrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-5-[(thien-2-ylcarbonyl) amino] phenyl}-N- (2- 2199 phenylethyl)-1 H-pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-5-[(thien-2-ylcarbonyl) amino] phenyl}-N- (2- 2200 methylbenzyl)-1 H-pyrazole-1-carboxamide 5-cyclopropyl-3- {2-hydroxy-5-[(thien-2-ylcarbonyl) amino] phenyl}-N-(3- 2201 methylbenzyl)-IH-pyrazole-l-carboxamide 5-cyclopropyl-3- {2-hydroxy-5-[(thien-2-ylcarbonyl) amino] phenyl}-N- (4- 2202 methylbenzyl)-lH-pyrazole-l-carboxamide N-(2-chlorobenzyl)-5-cyclopropyl-3- {2-hydroxy-5-[(thien-2- 2203 ylcarbonyl) amino] phenyl}-IH-pyrazole-1-carboxamide 5-cyclopropyl-N- (4-fluorobenzyl)-3-12-hydroxy-5- [ (thien-2- 2204 ylcarbonyl) amino] phenyl-lH-pyrazole-l-carboxamide 5-cyclopropyl-N- (3, 4-dichlorobenzyl)-3- {2-hydroxy-5-[(thien-2- 2205 ylcarbonyl) amino phenyl}-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {2-hydroxy-5-[(thien-2-ylcarbonyl) amino] phenyl}-N-(4- 2206 methoxybenzyl)-IH-pyrazole-1-carboxamide N-(sec-butyl)-5-cyclopropyl-3- {2-hydroxy-5-[(thien-2-ylcarbonyl) amino] phenyl}- 2207 IH-pyrazole-l-carboxamide 5-cyclopropyl-N- (2-fluorobenzyl)-3- {2-hydroxy-5- [ (thien-2- 2208 ylcarbonyl) amino] phenyl-1 H-pyrazole-1-carboxamide 5-cyclopropyl-N- (3-fluorobenzyl)-3- {2-hydroxy-5- [ (thien-2- 2209 ylcarbonyl) amino] phenyl-IH-pyrazole-l-carboxamide N, 5-dicyclopropyl-3- {2-hydroxy-5-[(thien-2-ylcarbonyl) amino] phenyl}-1H- 2210 pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-5-[(thien-2-ylcarbonyl) amino] phenyl}-N-isopropyl- 2211 1H-yrazole-1-carboxamide 5-cyclobutyl-N-ethyl-3- {2-hydroxy-5-[(thien-2-ylcarbonyl) aminophenyl}-1H- 2212 azole-1-carboxamide w N-allyl-5-cyclobutyl-3- {2-hydroxy-5-[(thien-2-ylcarbonyl) amino] phenyl}-lH- 2213 pyrazole-1-carboxamide w 5-cyclobutyl-3- {2-hydroxy-5-[(thien-2-ylcarbonyl) amino] phenyl}-N-propyl-lH- 2214 Dyrazole-1-carboxamide N-benzyl-5-cyclobutyl-3- {2-hydroxy-5-[(thien-2-ylcarbonyl) amino] phenyl}-lH- 2215 pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-5- [ (thien-2-ylcaxbonyl) amino] phenyl-N- (2- 2216 phenylethyl)-1H-pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-5- [ (thien-2-ylcarbonyl) ammo] phenyl}-N- (2- 2217 methylbenzyl)-1 H-pyrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-5-[(thien-2-ylcarbonyl) amino] phenyl}-N-(3- 2218 methylbenzyl)-1H-yrazole-1-carboxamide 5-cyclobutyl-3- {2-hydroxy-5- [ (thien-2-ylcarbonyl) amino] phenyl}-N- (4- 2219 methylbenzyl)-lH-pyrazole-l-carboxamide N-(2-chlorobenzyl)-5-cyclobutyl-3- {2-hydroxy-5-[(thien-2- 2220 ylcarbonyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclobutyl-N- (4-fluorobenzyl)-3- {2-hydroxy-5- [ (thien-2- 2221 ylcarbonyl) amino] phenyl}-IH-pyrazole-l-carboxamide 5-cyclobutyl-N- (3, 4-dichlorobenzyl)-3- {2-hydroxy-5- [ (thien-2- 2222 ylcarbonyl) amino] phenyl-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {2-hydroxy-5- [ (thien-2-ylcarbonyl) amino] phenyl}-N- (4- 2223 methoxybenzyl)-1 H-pyrazole-1-carboxamide N-(sec-butyl)-5-cyclobutyl-3- {2-hydroxy-5-[(thien-2-ylcarbonyl) amino] phenyl}- 2224 1H-pyrazole-1-carboxamide 5-cyclobutyl-N-(2-fluorobenzyl)-3-{2-hydroxy-5-[(thien-2- 2225 ylcarbonyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclobutyl-N- (3-fluorobenzyl)-3- {2-hydroxy-5- [ (thien-2- 2226 ylcarbonyl) aminolphenyl}-lH-pyrazole-l-carboxamide 5-cyclobutyl-N-cyclopropyl-3- {2-hydroxy-5-[(thien-2-ylcarbonyl) amino] phenyl}- 2227 IH-pyrazole-l-carboxamide 5-cyclopentyl-3- {2-hydroxy-5-[(thien-2-ylcarbonyl) amino] phenyl}-N-isopropyl- 2228 IH-pyrazole-1-carboxamide 5-cyclopentyl-N-ethyl-3-{2-hydroxy-5-[(thien-2-ylca-rbonyl) amino] phenyl}-lII- 2229 pyrazole-1-carboxamide N-allyl-5-cyclopentyl-3- {2-hydroxy-5-[(thien-2-ylcarbonyl) amino] phenyl}-lH- 2230 pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-5-[(thien-2-ylcarbonyl) amino] phenyl}-N-propyl-lH- 2231 pyrazole-l-carboxamide N-benzyl-5-cyclopentyl-3- {2-hydroxy-5-[(thien-2-ylcarbonyl) arnino] phenyl}-lH 2232 yrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-5-[(thien-2-ylcarbonyl) arnino] phenyl}-N-(2- 2233 phenylethyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {2-hydroxy-5-[(thien-2-ylcarbonyl) amino] phenyl}-N-(2- 2234 methylbenzyl)-lH-yrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-5-[(thien-2-ylcarbonyl) amino] phenyl}-N-(3- 2235 methylbenzyl)-IH-pyrazole-l-carboxamide 5-cyclopentyl-3- {2-hydroxy-5-[(thien-2-ylcarbonyl) amino] phenyl}-N-(4- 2236 methylbenzyl)-1H-pyrazole-1-carboxamide N-(2-chlorobenzyl)-5-cyclopentyl-3- {2-hydroxy-5-[(thien-2- 2237 ylcarbonyl) amino] phenyl}-lH-pyrazole-l-carboxamide 5-cyclopentyl-N- (4-fluorobenzyl)-3- {2-hydroxy-5- [ (thien-2- 2238 ylcarbonyl) amino] phenyl}-lH-pyrazole-1-carboxamide 5-cyclopentyl-N- (3, 4-dichlorobenzyl)-3-f2-hydroxy-5- [ (thien-2- 2239 ylcarbonyl) amino phenyl}-1 H-pyrazole-1-carboxamide 5-cyclopentyl-3- {2-hydroxy-5- [ (thien-2-ylcarbonyl) amino] phenyl}-N- (4- 2240 methoxybenzyl)-1 H-pyrazole-1-carboxamide N-(sec-butyl)-5-cyclopentyl-3- {2-hydroxy-5-[(thien-2-ylcarbonyl) amino] phenyl}- 2241 1 H-pyrazole-1-carboxamide 5-cyclopentyl-N-(2-fluorobenzyl)-3- {2-hydroxy-5-[(thien-2- 2242 ylcarbonyl) amino] phenyl}-1 H-pyrazole-1-carboxamide 5-cyclopentyl-N-(3-fluorobenzyl)-3- {2-hydroxy-5-[(thien-2- 2243 ylcarbonyl) amino phenyl}-lH-pyrazole-1-carboxaxnide 5-cyclopentyl-N-cyclopropyl-3- {2-hydroxy-5- [ (thien-2- 2244 ylcarbonyl) amino] phenyl}-1 H-pyrazole-1-carboxamide N- {5-cyclopropyl-1-[(isopropylamino) carbonyl]-lE-pyrazol-3-yl}-4- 2245 hydroxyphenyl) uinoxaline-2-carboxamide x A N- {5-cyclopropyl-1-[(ethylarnino) carbonyl]-lH-pyrazol-3-yl}-4- 2246 hydroxyphenyl) uinoxaline-2-carboxamide N- {1-[(allylainino) carbonyl]-5-cyclopropyl-lH-pyrazol-3-yl}-4- 2247 hydroxyphenyl) quinoxaline-2-carboxamide N- {5-cyclopropyl-1-[(propylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2248 hydroxyphenyl) uinoxaline-2-carboxamide N- (3-1- [ (benzylamino) carbonyl]-5-cyclopropyl-lH-pyrazol-3-yl}-4- 2249 hydroxyphenyl) quinoxaline-2-carboxamide N- [3- (5-cyclopropyl-l- { [ (2-phenylethyl) amin. o] carbonyl}-lH-pyrazol-3-yl)-4- 2250 hydroxyphenyl uinoxaline-2-carboxamide N- [3- (5-cyclopropyl-1- {[ (2-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2251 hydroxyphenyl] uinoxaline-2-carboxamide N-[3-(5-cyclopropyl-1- {[(3-methylbenzyl) arnino] carbonyl}-lH-pyrazol 3-yl)-4- 2252 hydroxyphenyl uinoxaline-2-carboxamide N- [3- (5-cyclopropyl-l- { [ (4-methylbenzyl) ammo] carbonyl}-lH-pyrazoI-3-yl)-4- 2253 hydroxyDhenyllquinoxaline-2-carboxamide N- [3- (l- {[ (2-chlorobenzyl) axnino] carbonyl}-5-cyclopropyl-lH-pyrazol-3-yl)-4- 2254 hydroxyphenyl] quinoxaline-2-carboxamide N- [3- (5-cyclopropyl-l- { [ (4-0uorobenzyl) ammo] carbonyl}-lH-pyrazol-3-yl)-4- 2255 hydroxyphenyl] quinoxaline-2-carboxamide N- [3- (5-cyclopropyl-1- { [ (3, 4-dichlorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)- 2256 4-hydroxyphenyl] quinoxaline-2-carboxamide N- [3- (5-cyclopropyl-l- { [ (4-methoxybenzyl) ammo] carbonyl}-lH-pyrazol-3-yl)-4- 2257 hydroxyphenyl] quinoxaline-2-carboxamide N- {1-[(sec-butylamino) carbonyl]-5-cyclopropyl-lH-pyrazol-3-yl}-4- 2258 hydroxyphenyl) quinoxaline-2-carboxamide N- [3- (5-cyclopropyl- 1- { [ (2-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2259 hydroxyphenyl] quinoxaline-2-carboxamide N- [3- (5-cyclopropyl-I-1 [ (3-fluorobenzyl) ainino] carbonyll-lH-pyrazol-3-yl)-4- 2260 hydroxyphenyl] quinoxaline-2-carboxamide N-(3- {5-cyclopropyl-1-[(cyclopropylamino) carbonyl]-1 H-pyrazol-3-yl3-4- 2261 hydroxyphenyl) quinoxaline-2-carboxamide N- (3- {5-cyclobutyl-l- [ (isopropylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2262 hydroxyphenyl) quinoxaline-2-carboxamide N- {5-cyclobutyl-1-[(ethylamino) carbonyl]-lH-p-yrazo1-3-yl}-4- 2263 hydroxyphenyl) quinoxaline-2-carboxamide N- (3- {1- [ (allylamino) carbonyl]-5-cyclobutyl-lH-pyrazol-3-yl}-4- 2264 hydroxyphenyl) quinoxaline-2-carboxamide N- {5-cyclobutyl-1-[(propylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2265 hydroxyphenyl) quinoxaline-2-carboxamide N- (3- {1- [ (benzylamino) carbonyl]-5-cyclobutyl-lH-pyrazol-3-yl}-4- 2266 hydroxyphenyl) quinoxaline-2-carboxamide N- [3- (5-cyclobutyl-l- { [ (2-phenylethyl) ammo] carbonyl}-lH-pyrazol-3-yl)-4- 2267 hydroxyphenyl] quinoxaline-2-carboxamide N-[3-(5-cyclobutyl-1- {[(2-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2268 hydroxyphenyl] quinoxaline-2-carboxamide N- [3- (5-cyclobutyl-1-1 [ (3-methylbenzyl) arnino] carbonyll-IH-pyrazol-3-yl)-4- 2269 hydroxyphenyl] quinoxaline-2-carboxamide N- [3- (5-cyclobutyl-1-1 [ (4-methylbenzyI) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2270 hydroxyphenyl] quinoxaline-2-carboxamide N-[3-(1- {[(2-chlorobenzyl) amino] carbonyl}-5-cyclobutyl-lH-pyrazol-3-yl)-4- 2271 hydroxyphenyl] uinoxaline-2-carboxamide N- [3- (5-cyclobutyl-1- f [ (4-fluorobenzyl) amino] carbonyl}-1H-pyrazol-3-yl)-4- 2272 hydroxyphenyl] xaline-2-carboxamide N- [3- (5-cyclobutyl-1- { [ (3, 4-dichlorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2273 hydroxyphenyl] quinoxaline-2-carboxamide a N-[3-(5-cyclobutyl-1-{[(4-methoxybenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2274 hydroxyphenyl] quinoxaline-2-carboxamide N- (3- {1- [ (sec-butylamino) carbonyl]-5-cyclobutyl- lH-pyrazol-3-yl}-4- 2275 hydroxyDhenyl) quinoxaline-2-carboxamide N- [3- (5-cyclobutyl-1- f [ (2-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2276 hydroxyphenyl] quinoxaline-2-carboxamide N- [3- (5-cyclobutyl-1-1 [ (3-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2277 hydroxyDhenyl] quinoxaline-2-carboxamide N- (3- {5-cyclobutyl-l- [ (cyclopropylammo) carbonyl]-lH-pyrazol-3-yl}-4- 2278 hydroxyphenyl) quinoxaline-2-carboxamide N- (3- {5-cyclopentyl-l- [ (isopropylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2279 hydroxyphenyl) quinoxaline-2-carboxamide N-(3- {5-cyclopentyl-1-[(ethylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2280 hydroxyphenyl) quinoxaline-2-carboxamide N- {1-[(allylamino) carbonyl]-5-cyclopentyl-1 H-pyrazol-3-yl}-4- 2281 hydroxyphenyl) quinoxaline-2-carboxamide N-(3- {5-cyclopentyl-1-[(propylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2282 hydroxyphenyl) quinoxaline-2-carboxamide N- (3-f 1- [ (benzylamino) carbonyl]-5-cyclopentyl-lH-pyrazol-3-yl}-4- 2283 hydroxyphenyl) quinoxaline-2-carboxamide A A N- [3- (5-cyclopentyl-l- { [ (2-phenylethyI) amino] carbonyll-lH-pyrazol-3-yl)-4- 2284 hydroxyphenyl] quinoxaline-2-carboxamide N- [3- (5-cyclopentyl-1- { [ (2-methylbenzyl) ammo] carbonyl}-lH-pyrazol-3-yl)-4- 2285 hydroxyphenyl] quinoxaline-2-carboxamide N- [3- (5-cyclopentyl-1- {[ (3-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2286 hydroxyphenyl] quinoxaline-2-carboxamide N- [3- (5-cyclopentyl-l- { [ (4-methylbenzyl) ammo] carbonyl}-lH-pyrazol-3-yl)-4- 2287 hydroxyphenyl] quinoxaline-2-carboxamide N- [3- (1- [ (2-chlorobenzyl) amino] carbonyl}-5-cyclopentyl-lH-pyrazol-3-yl)-4- 2288 hydroxyphenyl] quinoxaline-2-carboxamide N- [3- (5-cyclopentyl-1- {[ (4-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2289 hydroxyphenyl] uinoxaline-2-carboxamide N- [3- (5-cyclopentyl-l- { [ (3, 4-dichlorobenzyl) amino] carbonyl}-IH-pyrazol-3-yl)- 2290 4-hydroxyphenyl] quinoxaline-2-carboxamide N- [3- (5-cyclopentyl-1- { [ (4-methoxybenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2291 hydroxyphenyl] quinoxaline-2-carboxamide N- {1-[(sec-butylamino) carbonyl]-5-cyclopentyl-lH-pyrazol-3-yl}-4- 2292 hydroxyphenyl) quinoxaline-2-carboxamide N- [3- (5-cyclopentyl-1- {[ (2-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2293 hydroxyphenyl] quinoxaline-2-carboxamide N- [3- (5-cyclopentyl-1-1 [ (3-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2294 hydroxyphenyl] quinoxaline-2-carboxamide N-(3- {5-cyclopentyl-1-[(cyclopropylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2295 hydroxyphenyl) quinoxaline-2-carboxamide N-(3-{5-cyclopropyl-1-[(isopropylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2296 hydroxyphenyl) nicotinamide N- {5-cyclopropyl-1-[(ethylamino) carbonyl]-1 H-pyrazol-3-yl}-4- 2297 hydroxyphenyl) nicotinamide N-(3-{1-[(allylamino) carbonyl]-5-cyclopropyl-lH-pyrazol-3-yl}-4- 2298 hydroxyphenyl) nicotinamide N-(3- {5-cyclopropyl-1-[(propylamino) carbonyl]-lH-pyrazol-3-yl}-4 2299 hydroxyphenyl) nicotinamide N-(3-{1-[(benzylamino) carbonyl]-5-cyclopropyl-lH-pyrazol-3-yl}-4- 2300 hydroxyphenyl) nicotinamide N- [3- (5-cyclopropyl-l- { [ (2-phenylethyl) ammo] carbonyl}-lH-pyrazol-3-yl)-4- 2301 hydroxyphenyl] nicotinamide N- [3- (5-cyclopropyl-1- {[ (2-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2302 hydroxyphenyl] nicotinamide N- [3- (5-cyclopropyl-1- { [ (3-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2303 hydroxyphenyl] nicotinamide N- [3- (5-cyclopropyl-1- { [ (4-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2304 hydroxyphenylgnicotinamide N- [3- (l- {[ (2-chlorobenzyl) amino] carbonyl}-5-cyclopropyl-1H-pyrazol-3-yl)-4- 2305 hydroxyphenyl] nicotinamide N-[3-(5-cyclopropyl-1- {[(4-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2306 hydroxyphenyl] nicotinamide N- [3- (5-cyclopropyl-1- { [ (3, 4-dichlorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)- 2307 4-hydroxyphenyl] nicotinamide N- [3- (5-cyclopropyl-1- f [ (4-methoxybenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2308 hydroxyphenyl] nicotinamide N- {1-[(sec-butylamino) carbonyl]-5-cyclopropyl-lH-pyrazol-3-yl}-4- 2309 hydroxyphenyl) nicotinamide N- [3- (5-cyclopropyl-l- f [ (2-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2310 hydroxyphenyl] nicotinamide N- [3- (5-cyclopropyl-l- { [ (3-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2311 hydroxyphenyl] nicotinamide N- {5-cyclopropyl-1-[(cyclopropylamino) carbonyl3-lH-pyrazol-3-yl}-4- 2312 hydroxyphenyl) nicotinamide N- {5-cyclobutyl-1-[(isopropylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2313 hydroxyphenyl) nicotinamide N-(3- {5-cyclobutyl-1-[(ethylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2314 hydroxyphenyl) nicotinamide N- (3- {1- [ (allylamino) carbonyl]-5-cyclobutyl-lH-pyrazol-3-yl}-4- 2315 hydroxyphenyl) nicotinamide N-(3- {5-cyclobutyl-1-[(propylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2316 hydroxyphenyl) nicotinamide N- (3- {1- [ (benzylamino) carbonyl]-5-cyclobutyl-lH-pyrazol-3-yl}-4- 2317 hydroxyphenyl) nicotinamide N- [3- (5-cyclobutyl-l- { [ (2-phenylethyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2318 hydroxyphenyljnicotmamide N- [3- (5-cyclobutyl-l-f [ (2-methylbenzyl) amino] carbonyl)-lH-pyrazol-3-yl)-4- 2319 hydroxyphenyljnicotmamide N- [3- (5-cyclobutyl-1- {[ (3-methylbenzyl) arnino] carbonyl}-lH-pyrazol-3-yl)-4- 2320 hydroxyphenyl] nicotinamide N- [3- (5-cyclobutyl-1- {[ (4-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2321 hydroxyphenyl] nicotinamide N- [3- (l- { [ (2-chlorobenzyl) amino] carbonyl}-5-cyclobutyl-lH-pyrazol-3-yl)-4- 2322 hydroxyphenyl] nicotinamide N- [3- (5-cyclobutyl-1- { [ (4-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2323 hydroxyphenyl] nicotinamide N- [3- (5-cyclobutyl-l- { [ (3, 4-dichlorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2324 hydroxyphenyllmcotmamide N- [3- (5-cyclobutyl-l-f [ (4-methoxybenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2325 hydroxyphenyl] nicotinaniide N- (3- 1- [ (sec-butylamino) carbonyl]-5-cyclobutyl-lH-pyrazol-3-yl}-4- 2326 hydroxyphenyl) nicotinamide N- [3- (5-cyclobutyl- 1-1 [ (2-fluorobenzyl) aminolcarbonyl}-1H-pyrazol-3-yl)-4- 2327 hydroxyphenyl nicotinamide N- [3- (5-cyclobutyl-1- { [ (3-fluorobenzyl) ammo] carbonyl}-lH-pyrazoI-3-yl)-4- 2328 hydroxyphenyl] nicotinamide N-(3- {5-cyclobutyl-1-[(cyclopropylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2329 hydroxyphenyl) nicotinamide N-(3- {5-cyclopentyl-1-[(isopropylamino) carbonyl]-lE-pyrazol-3-yl}-4- 2330 hydroxyphenyl) nicotinamide N-(3- {5-cyclopentyl-1-[(ethylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2331 hydroxyphenyl) nicotinamide N- (3- {1- [ (allylamino) carbonyl]-5-cyclopentyl-lH-pyrazol-3-yl}-4- 2332 hydroxyphenyl) nicotinamide N- {5-cyclopentyl-l-[(propylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2333 hydroxyphenyl) nicotinamide N- (3- {1- [ (benzylammo) carbonyl]-5-cyclopentyl- lH-pyrazoI-3-yl}-4- 2334 hydroxyphenyl) nicotinamide N- [3- (5-cyclopentyl-. 1- { [ (2-phenylethyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2335 hydroxyphenyl nicotinamide N- [3- (5-cyclopentyl-l- { [ (2-methylbenzyl) arnino] carbonyl}-lH-pyrazol-3-yl)-4- 2336 hydroxyphenyl] nicotinamide N- [3- (5-cyclopentyl-l- { [ (3-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2337 hydroxyphenyl] nicotinamide N- [3- (5-cyclopentyl-l- { [ (4-methylbenzyl) ammo] carbonyl}-lH-pyrazoI-3-yl)-4- 2338 hydroxyphenyl] nicotinamide N- [3- (l- { [ (2-chlorobenzyl) amino] carbonyl}-5-cyclopentyl-lH-pyrazol-3-yl)-4- 2339 hydroxyphenyl] nicotinamide A N- [3- (5-cyclopentyl-1- { [ (4-iluorobenzyl) amino] carbonyl}-1H-pyrazol-3-yl)-4- 2340 hydroxyphenyl] nicotinamide N- [3- (5-cyclopentyl-l- { [ (3, 4-dichlorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)- 2341 4-hydroxyphenyl] nicotinamide N-[3-(5-cyclopentyl-1- {[(4-methoxybenzyl) arnino] carbonyl}-lH-pyrazol-3-yl)-4- 2342 hydroxyphenyl] nicotinamide N-(3- {1-[(sec-butylarnino) carbonyl]-5-cyclopentyl-lH-pyrazol-3-yl}-4- 2343 hydroxyphenyl) nicotinamide N- [3- (5-cyclopentyl-1- f [ (2-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2344 hydroxyphenyl] nicotinamide N- [3- (5-cyclopentyl-1- { [ (3-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2345 hydroxyDhenyl] nicotinamide N- (3- {5-cyclopentyl-l- [ (cyclopropylammo) carbonyl]-lH-pyrazol-3-yl}-4- 2346 hydroxyphenyl) nicotinamide v N-(3-{5-cyclopropyl-1-f (isopropylarnino) carbonyl]-lH-pyrazol-3-yl}-4- 2347 hydroxyphenyl) isonicotinamide N-(3-{5-cyclopropyl-1-[(ethylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2348 hydroxyphenyl) isonicotinamide N- (3- 1- [ (allylamino) carbonyl]-5-cyclopropyl-lH-pyrazol-3-yl}-4- 2349 hydroxyphenyl) isonicotinamide N-(3- {5-cyclopropyl-l-[(propylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2350 hydroxyphenyl) isonicotinamide N- {1-[(benzylamino) carbonyl]-5-cyclopropyl-lH-pyrazol-3-yl3-4- 2351 hydroxyphenyl) isonicotinamide N- [3- (5-cyclopropyl-l- { [ (2-phenylethyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2352 hydroxyphenyl] isonicotinamide N- [3- (5-cyclopropyl-l- { [ (2-methylbenzyl) ammo] carbonyl}-lH-pyrazol-3-yl)-4- 2353 hydroxyphenyl] isonicotinamide N- [3- (5-cyclopropyl-l- { [ (3-methylbenzyl) ammo] carbony !}-lH-pyrazol-3-yl)-4- 2354 hydroxyphenyl] isonicotinamide N- [3- (5-cyclopropyl-l- { [ (4-methylbenzyl) ammo] carbonyl}-lH-pyrazol-3-yl)-4- 2355 hydroxyphenyllisonicotinamide N- [3- ( 1- [ (2-chlorobenzyl) amino] carbonyl}-5-cyclopropyl-lH-pyrazol-3-yl)-4- 2356 hydroxyphenyl] isonicotinamide N- [3- (5-cyclopropyl-l- { [ (4-fluorobenzyl) ammo] carbonyl}-lH-pyrazol-3-yl)-4- 2357 hydroxyphenyl] isonicotinamide N- [3- (5-cyclopropyl-l- { [ (3, 4-dichlorobenzyl) amino] ca, rbonyl}-lH-pyrazol-3-yl)- 2358 4-hydroxyphenyl] isonicotinamide N- [3- (5-cyclopropyl-l- { [ (4-methbxybenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2359 hydroxyphenyl] isonicotinamide N-(3- {1-[(sec-butylamino) carbonyl]-5-cyclopropyl-lH-pyrazol-3-yl}-4- 2360 hydroxyphenyl) isonicotinamide N- [3- (5-cyclopropyl-1- {[ (2-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2361 hydroxyphenyl] isonicotinarnide N- [3- (5-cyclopropyl-l- { [ (3-fluorobenzyl) ammo] carbonyl}-lH-pyrazol-3-yl)-4- 2362 hydroxyphenyl] isonicotinamide N- {5-cyclopropyl-1-[(cyclopropylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2363 hydroxyphenyl) isonicotinamide N-(3- {5-cyclobutyl-1-[(isopropylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2364 hydroxyphenyl) isonicotinamide N- (3- {5-cyclobutyl-l- [ (ethylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2365 hydroxyphenyl) isonicotinamide N-(3- {1-[(allylamino) carbonyl]-5-cyclobutyl-1 H-pyrazol-3-yl}-4- 2366 hydroxyphenyl) isonicotinamide N- (3- {5-cyclobutyl-l- [ (propylammo) carbonyl]-lH-pyrazol-3-yl}-4- 2367 hydroxyphenyl) isonicotinamide N- (3- {1-j (benzylamino) carbonyl]-5-cyclobutyl-1H-pyrazol-3-yl}-4- 2368 hydroxyphenyl) isonicotinamide N- [3- (5-cyclobutyl-l- { [ (2-phenylethyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2369 hydroxyphenyl] isonicotinamide _ _ N- [3- (5-cyclobutyl-1- f [ (2-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2370 hydroxyphenyl] isonicotinamide N- [3- (5-cyclobutyl-l- { [ (3-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2371 hydroxyphenyl] isonicotinamide N- [3- (5-cyclobutyl-1- [ (4-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2372 hydroxyphenyl] isonicotinamide N- [3- (1- { (2-chlorobenzyl) amino] carbonyl}-5-cyclobutyl-lH-pyrazol-3-yl)-4- 2373 hydroxyphenyl] isonicotinamide N- [3- (5-cyclobutyl-1- { [ (4-uorobenzyl) ammo] carbonyl}-lH-pyrazol-3-yl)-4- 2374 hydroxyphenyl] isonicotinamide s J _ N- [3- (5-cyclobutyl-1- { [ (3, 4-dichlorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2375 hydroxyphenyl] isonicotinamide N- [3- (5-cyclobutyl-l- { [ (4-methoxybenzyl) ammo] carbonyl}-lH-pyrazol-3-yl)-4- 2376 hydroxyphenyl] isonicotinamide N- {1-[(sec-butylamino) carbonyl]-5-cyclobutyl-lH-pyrazol-3-yl}-4- 2377 hydroxyphenyl) isonicotinamide N- [3- (5-cyclobutyl-l- { [ (2-fluorobcnzyl) animo] carbonyl}-lH-pyrazol-3-yl)-4- 2378 hydroxyphenyl] isonicotinamide N- [3- (5-cyclobutyl-1- { [ (3-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2379 hydroxyphenyl] isonicotinamide N-(3- {5-cyclobutyl-1-[(cyclopropylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2380 hydroxyphenyl) isonicotinamide N-(3- {5-cyclopentyl-1-[(isopropylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2381 hydroxyphenyl) isonicotinamide N-(3- {5-cyclopentyl-1-[(ethylamino) carbonyl]-lH-pyrazol-3-yl3-4- 2382 hydroxyphenyl) isonicotinamide N-(3- {1-[(allylamino) carbonyl]-5-cyclopentyl-lH-pyrazol-3-yl}-4- 2383 hydroxyphenyl) isonicotinamide N- (3- {5-cyc lopentyl-1- [(propylamino) c arb onyl]-1 H-pyraz ol-3-yl}-4- 2384 hydroxyphenyl) isonicotinamide N- {I-[(benzylamino) carbonyl]-5-cyclopentyl-1 H-pyrazol-3-yl}-4- 2385 hydroxyphenyl) isonicotinamide N- [3- (5-cyclopentyl-l- { [ (2-phenylethyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2386 hydroxyphenyl] isonicotinamide N- [3- (5-cyclopentyl-l- { [ (2-methylbenzyl) ammo] carbonyl}-lH-pyrazol-3-yl)-4- 2387 hydroxyphenyl] isonicotinamide N- [3- (5-cyclopentyl-1- { [ (3-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2388 hydroxyphenyl] isonicotinamide N-[3-(5-cyclopentyl-1-{[(4-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2389 hydroxyphenyl] isonicotinamide N- [3- (1- { [ (2-chlorobenzyl) amino] carbonyl}-5-cyclopentyl-lH-pyrazol-3-yl)-4- 2390 hydroxyphenyllisonicotinainide v N- [3- (5-cyclopentyl-l-f [ (4-fluorobenzyl) anaino] carbonyl}-IH-pyrazol-3-yl)-4- 2391 hydroxyphenyl] isonicotinamide N- [3- (5-cyclopentyl-l-f [ (3, 4-dichlorobenzyl) amino] carbonyl}-IH-pyrazol-3-yl)- 2392 4-hydroxyphenyl] isonicotinamide N- [3- (5-cyclopentyl-1- [ (4-methoxybenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2393 hydroxyphenyl] isonicotinamide N- (3- {l- [ (sec-butylamino) carbonyl]-5-cyclopentyl-lH-pyrazol-3-yI}-4- 2394 hydroxyphenyl) isonicotinamide N- [3- (5-cyclopentyl-1- f [ (2-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2395 hydroxyphenyl] isonicotinamide 19-[3-(5-cyclopentyl-1-{[(3-fluorobenzyl) arnino] carbonyl3-lH-pyrazol-3-yl)-4- 2396 hydroxyphenyl] isonicotinamide N-(3- {5-cyclopentyl-1- [(cyclopropylam-ino) carbonyl]-lH-pyrazol-3-yl}-4- 2397 hydroxyphenyl) isonicotinamide 3- {5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- 2398 isopropyl-lH-pyrazole-1-carboxamide 3- {5- [ (l, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- 2399 ethyl-IH-pyrazole-1-carboxamide N-allyl-3- {5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5- 2400 cyclopropyl-1 H-pyrazole-1-carboxamide 3- 5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- 2401 ro yl-1H-yrazole-1-caxboxamide 3- 5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-N-benzyl-5- 2402 cyelopropyl-1 H-pyrazole-1-earboxamide 3- {5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- 2403 (2-phenylethyl)-lH-pyrazole-l-carboxamide 3- {5- [ (1, 3-benzodioxol-5-ylcarbonyl) ammo]-2-hydroxyphenyl}-5-cyclopropyl-N- 2404 (2-methylbenzyl)-lH-pyrazole-1-carboxamide 3- {5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- 2405 (3-methylbenzyl)-1H-yrazole-1-carboxamide 3- {5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- 2406 (4-methylbenzyl)-lH-pyrazole-l-carboxamide 3- {5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-N- (2- 2407 chlorobenzyl)-5-cyclopropyl-lH-pyrazole-l-carboxamide 3- {5-[(1, 3-benzodioxol-5-ylcarbonyl) amino3-2-hydroxyphenyl}-5-cyclopropyl-N- 2408 (4-fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- 2409 (3, 4-dichlorobenzyl)-lH-pyrazole-l-carboxamide 3- {5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- 2410 (4-methoxybenzyl)-IH-pyrazole-1-carboxamide 3- {5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-N- (sec-butyl)-5- 2411 cyclopropyl-1H-pyrazole-1-carboxamide 3- {5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- 2412 (2-fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {5- [ (l, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- 2413 (3-fluorobenzyl)-1H-pyrazole-1-carboxamide 3- {5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-N, 5- 2414 dicyclopro yl-1H-pyrazole-1-carboxamide 3- {5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- 2415 isopropyl-lH-pyrazole-1-carboxamide 3- {5- [ (1, 3-benzodioxol-5-ylcarbonyl) ammo]-2-hydroxyphenyl}-5-cyclobutyl-N- 2416 ethyl-lH-pyrazole-l-carboxamide N-allyl-3-f5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl)-5- 2417 cyclobutyl-lH-pyrazole-l-carboxamide 3- {5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- 2418 propyl-lH-pyrazole-l-carboxamide 3- {5- [ (l, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-N-benzyl-5- 2419 cyclobutyl-lH-pyrazole-l-carboxamide 3- {5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- 2420 (2-phenylethyl)-lH-pyrazole-l-carboxamide 3- {5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- 242-methylbenzyl)-lH-pyrazole-l-carboxamide 3- {5- [ (l, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- 2422 (3-methylbenzyl)-lH-pyrazole-1-carboxamide 3- {5-[(1, 3-benzodíoxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- 2423 (4-methylbenzyl)-lH-pyrazole-l-carboxamide 3- 5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-N- (2- 2424 chlorobenzyl)-5-cyclobutyl-1 H-pyrazole-1-carboxamide 3- {5-[(1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- 2425 (4-fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- 2426 (3, 4-dichlorobenzyl)-1 H-pyrazole-1-carboxamide 3- {5-[(1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- 2427 (4-methoxybenzyl)-1 H-pyrazole-1-carboxamide 3- {5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-N- (sec-butyl)-5- 2428 cyclobutyl-lH-pyrazole-l-carboxamide 3- {5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- 2429 (2-fluorobenzyl)-1 H-pyrazole-1-carboxamide 3- {5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- 2430 (3-fluorobenzyl)-lH-pyrazole-l-carboxamide 3- 5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- 2431 cyclopropyl-lH-pyrazole-l-carboxamide 3-f 5- [ (1, 3-benzodioxol-5-ylcaxbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 2432 isopropyl-1H-pyrazole-1-carboxamide 3- {5- [ ( 1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 2433 ethyl-1H-pyrazole-l-carboxamide N-allyl-3- {5-[(1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5- 2434 cyclopentyl-1 H-pyrazole-I-carboxamide 3- 5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 2435 propyl-lH-pyrazole-l-carboxamide 3- {5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-N-benzyl-5- 2436 cyclopentyl-1 H-pyrazole-1-carboxamide 3- {5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 2437 (2-phenylethyl)-lH-pyrazole-l-carboxamide 3- {5- [ (l, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 2438 (2-methylbenzyl)-lH-pyrazole-l-carboxamide A 3- {5-[(1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 2439 (3-methylbenzyl)-lH-pyrazole-l-carboxamide 3- {5- [ ( 1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 2440 (4-methylbenzyl)-lH-pyrazole-l-carboxamide 3-f 5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-N- (2- 2441 chlorobenzyl)-5-cyclopentyl-1H-pyrazole-l-carboxamide 3- 5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 2442 (4-fluorobenzyl)-lH-pyrazole-l-carboxamide 3- 5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 2443 (3, 4-dichlorobenzyl)-1 H-pyrazole-1-carboxamide 3- 5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 2444 (4-methoxybenzyl)-lH-pyrazole-l-carboxamide 3- {5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-N- (sec-butyl)-5- 2445 cyclopentyl-1 H-pyrazole-1-carboxamide 3- [ (1, 3-benzodioxol-5-ylcarbonyl) arnino]-2-hydroxyphenyl}-5-cyclopentyl-N- 2446 (2-fluorobenzyl)-lH-pyrazole-l-carboxamide 3-f 5- [ (1, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 2447 (3-fluorobenzyl)-1H-yrazole-1-carboxamide 3- {5- [ (l, 3-benzodioxol-5-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 2448 cyclopropyl-1 H-pyrazole-1-carboxamide 5-cyclopropyl-3- {5-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-isopropyl-lH- 2449 pyrazole-1-carboxamide 5-cyclopropyl-N-ethyl-3- 5- [ (2-ethylbutanoyl) amino]-2-hydroxyphenyl}-lH- 2450 pyrazole-l-carboxamide N-allyl-5-cyclopropyl-3- {5-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-lH- 2451 pyrazole-1-carboxamide 5-cyclopropyl-3- {5- [ (2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-propyl-lH- 2452 pyrazole-1-carboxamide N-benzyl-5-cyclopropyl-3- {5-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl3-1H- 2453 pyrazole-1-carboxamide 5-cyclopropyl-3- {5-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-(2- 2454 phenylethyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {5-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-(2- 2455 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {5- [ (2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N- (3- 2456 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- {5-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-(4- 2457 methylbenzyl)-lH-pyrazole-l-carboxarnide N-(2-chlorobenzyl)-5-cyclopropyl-3- {5-[(2-ethylbutanoyl) amino]-2- 2458 hydroxyphenyl}-1 H-pyrazole-1-carboxamide 5-cyclopropyl-3- 5- [ (2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N- (4- 2459 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-N-(3, 4-dichlorobenzyl)-3- {5-[(2-ethylbutanoyl) amino]-2- 2460 hydroxyDhenyl}-lH-syrazole-l-carboxamide 5-cyclopropyl-3- {5-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl3-N-(4- 2461 methoxybenzyl)-lH-pyrazole-l-carboxamide N-(sec-butyl)-5-cyclopropyl-3- {5-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl3- 2462 1 H-pyrazole-1-carboxamide 5-cyclopropyl-3- {5-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-(2- 2463 fluorobenzyl)-I H-pyrazole-1-carboxamide 5-cyclopropyl-3- {5-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-(3- 2464 fluorobenzyl)-lH-pyrazole-l-carboxamide N, 5-dicyclopropyl-3-{5-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-1H- 2465 pyrazole-1-carboxamide _ 5-cyclobutyl-3- {5-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-isopropyl-1 H- 2466 pyrazole-1-carboxamide 5-cyclobutyl-N-ethyl-3- (5- [ (2-ethylbutanoyl) amino]-2-hydroxyphenyl}-lH- 2467 pyrazole-1-carboxamide N-allyl-5-cyclobutyl-3- {5-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl3-IH- 2468 pyrazole-I-carboxamide 5-cyclobutyl-3- {5-[(2-ethylbutanoyl) arnino]-2-hydroxyphenyl}-N-propyl-lH- 2469 pyrazole-1-carboxamide N-benzyl-5-cyclobutyl-3- {5-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-lH 2470 pyrazole-1-carboxamide 5-cyclobutyl-3- {5-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-(2-phenylethyl)- 2471 1 H-pyrazole-1-carboxamide 5-cyclobutyl-3- (5- [ (2-ethylbutanoyl) amino]-2-hydroxyphenyll-N- (2- 2472 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {5-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-(3- 2473 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {5-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-(4- 2474 methylbenzyl)-lH-pyrazole-l-carboxamide N-(2-chlorobenzyl)-5-cyclobutyl-3- {5-[(2-ethylbutanoyl) amino]-2- 2475 hydroxyphenyl}-IH-pyrazole-1-carboxamide 5-cyclobutyl-3- {5-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-(4- 2476 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-N- (3, 4-dichlorobenzyl)-3- {5- [ (2-ethylbutanoyl) amino]-2- 2477 hydroxyphenyl}-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {5-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-(4- 2478 methoxybenzyl)-lH-pyrazole-l-carboxamide N- (sec-butyl)-5-cyclobutyl-3- f 5- [ (2-ethylbutanoyl) amino]-2-hydroxyphenyl}-1H- 2479 pyrazole-I-carboxamide 5-cyclobutyl-3- {5-[(2-ethylbutanoyl) arnino]-2-hydroxyphenyl}-N-(2- 2480 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- {5- [ (2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N- (3- 2481 fluorobenzyl)-1H-pyrazole-1-carboxamide 5-cyclobutyl-N-cyclopropyl-3- {5-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}- 2482 1 H-pyrazole-1-carboxamide 5-cyclopentyl-3- 5- [ (2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-isopropyl-lH- 2483 pyrazole-1-carboxamide 5-cyclopentyl-N-ethyl-3- {5-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-1H- 2484 pyrazole-1-carboxamide N-allyl-5-cyclopentyl-3- {5-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-1H- 2485 pyrazole-1-carboxamide 5-cyclopentyl-3- {5-[(2-ethylbutanoyl) arnino]-2-hydroxyphenyl}-N-propyl-lH- 2486 pyrazole-1-carboxamide N-benzyl-5-cyclopentyl-3- {5-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-1H- 2487 pyrazole-1-carboxamide 5-cyclopentyl-3-{5-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-(2- 2488 Phenylethyl)-1 H-syrazole-1-carboxamide 488 5-cyclopentyl-3- S- [ (2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N- (2- 2489 methylbenzyl)-lH-pyrazole-1-carboxamide 2 5-cyclopentyl-3- {5-[(2-ethylbutanoyl) arnino]-2-hydroxyphenyl}-N-(3- 2490 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {5-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-(4- 2491 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {5-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-(4- 2492 fluorobenzyl)-IH-pyrazole-l-carboxamide 5-cyclopentyl-3- {5- [ (2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N- (4- 2493 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-N- (3, 4-dichlorobenzyl)-3- 5- [ (2-ethylbutanoyl) amino]-2- 2494 hydroxyphenyl-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {5-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-(4- 2495 methoxybenzyl)-lH-pyrazole-l-carboxamide N-(sec-butyl)-5-cyclopentyl-3- {5-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}- 2496 1H-yrazole-1-carboxamide 5-cyclopentyl-3- {5-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N-(2- 2497 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- {5- [ (2-ethylbutanoyl) amino]-2-hydroxyphenyl}-N- (3- 2498 fluorobenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-N-cyclopropyl-3- {5-[(2-ethylbutanoyl) amino]-2-hydroxyphenyl}- 2499 lH-Dyrazole-l-carboxamide A 3- {5- [ (1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- 2500 isopropyl-lH-pyrazole-l-carboxainide 3- {5- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- 2501 ethyl-lH-pyrazoIe-1-carboxamide x N-allyl-3- {5- [ (1-benzothien-2-ylcarbonyl) ammo]-2-hydroxyphenyl}-5- 2502 cyclopropyl-1H-pyrazole-1-carboxamide s x 3- {5-[(1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- 2503 sropvl-lH-syrazole-l-carboxamide 3- {5- [ ( 1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-N-benzyl-5- 2504 cycloproDyl-1 H-Dyrazole-1-carboxamide s 3- 5- [ (1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (2- 2505 shenylethyl)-lH-pyrazole-l-carboxamide A 3- {5- [ (1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (2- 2506 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {5- [ (1-benzothien-2-ylcarbonyl) am. ino]-2-hydroxyphenyl}-5-cyclopropyl-N- (3- 2507 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {5- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (4- 2508 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {5- [ (1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-N- (2-chlorobenzyl)- 2509 5-cyclopropyl-lH-pyrazole-l-carboxamide 3- {5- [ (1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (4- 2510 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {5-[(1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- 2511 (3, 4-dichlorobenzyl)-1H-pyrazole-1-carboxamide 3- {5- [ (1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (4- 2512 methoxybenzyl)-IH-pyrazole-l-carboxamide 3- {5- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-N- (sec-butyl)-5- 2513 cyclopropyl-lH-pyrazole-l-carboxamide 3- {5-[(1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N-(2- 2514 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- S- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopropyl-N- (3- 2515 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {5-[(1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-N, 5-dicyclopropyl- 2516 1H-yrazole-1-carboxamide L 3- 5- [ (1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- 2517 isooronyl-lH-pyrazole-l-carboxarnide 3- {5- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- 2518 ethyl-1H-yrazole-1-carboxamide N-allyl-3-{5-[(1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl- 2519 1 H-pyrazole-1-carboxamide 3- {5- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- 2520 propyl-1 H-pyrazole-1-carboxamide 3- {5- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-N-benzyl-5- 2521 cyclobutyl-lH-pyrazole-1-carboxamide 3- {5- [ (1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (2- 2522 phenylethyl)-lH-pyrazole-l-carboxamide 3- {5- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (2- 2523 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {5- [ ( 1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (3- 2524 methylbenzyl)-lH-pyrazole-l-carboxamide 3- 5- [ (1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (4- 2525 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {5-[(1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-N-(2-chlorobenzyl)- 2526 5-cyclobutyl-lH-pyrazole-l-carboxamide 3- {5- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (4- 2527 fluorobenzyl)-1 H-pyrazole-1-carboxamide 3- {5- [ (1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (3, 4- 2528 dichlorobenzyl)-lH-pyrazole-l-carboxamide 3- {5- [ (l-benzotmen-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (4- 2529 methoxybenzyl)-lH-pyrazole-l-carboxamide 3- {5- [ (I-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-N- (sec-butyl)-5- 2530 cyclobutyl-1 H-pyrazole-1-carboxamide 3- {5- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (2- 2531 fluorobenzyl)-lH-pyrazole-l-carboxarnide 3- {5- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- (3- 2532 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {5- [ (I-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclobutyl-N- 2533 cycloDroDyl-lH-pyrazole-1-carboxainide t 3-f{5- [ (1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 2534 isopropyl-IH-pyrazole-1-carboxamide s A 3- {5- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 2535 ethyl-lH-pyrazole-1-carboxamide N-allyl-3- {5- [ (1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5- 2536 cycIopentyl-lH-pyrazole-1-carboxamide 3- 5- [ (1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 2537 propyl-lH-pyrazole-l-carboxamide 3- 5- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-N-benzyl-5- 2538 cyclopentyl-lH-pyrazole-l-carboxamide 3- 5- [ (1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (2- 2539 phenylethyl)-lH-pyrazole-l-carboxamide 3- {5-[(1-benzothien-2-ylCarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-(2- 2540 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {5- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (3- 2541 methylbenzyl)-lH-pyrazole-l-carboxamide 3- {5- [ (I-benzothien-2-ylcarbonyl) atnino]-2-hydroxyphenyll-5-cyclopentyl-N- (4- 2542 methylbenzyl)-lH-pyrazole-1-carboxamide 3- {5- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-N- (2-chlorobenzyl)- 2543 5-cyclopentyl-lH-pyrazole-l-carboxamide 3- {5- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (4- 2544 fluorobenzyl)-lH-pyrazole-l-carboxarnide A 3- {5- [ (l-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 2545 (3, 4-dichlorobenzyl)-1 H-pyrazole-1-carboxamide 3- {5- [ (l-benzothien72-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (4- 2546 methoxybenzyl)-lH-pyrazole-l-carboxamide 3- {5- [ (l-benzothien-2-ylcarbonyl) ammo]-2-hydroxyphenyl}-N- (sec-butyl)-5- 2547 eyelopentyl-lH-pyrazole-l-earboxamide 3- 5- [ (1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- (2- 2548 fluorobenzyl)-1H-pyrazole-1-carboxamide 3- {5-[(1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N-(3- 2549 fluorobenzyl)-lH-pyrazole-l-carboxamide 3- {5- [ (1-benzothien-2-ylcarbonyl) amino]-2-hydroxyphenyl}-5-cyclopentyl-N- 2550 cyclopropyl-lH-pyrazole-1-earboxamide 2-chloro-N-(3- {S-cyclopropyl-1-[(isopropylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2551 hydroxyphenyl) nicotinamide 2-chloro-N-(3- {5-cyelopropyl-1-[(ethylarnino) carbonyl]-lH-pyrazol-3-yl}-4- 2552 hydroxyphenyl) nicotinamide N- {1-[(allylarnino) carbonyl]-5-cyclopropyl-l H-pyrazol-3-yl}-4- 2553 hydroxyphenyl)-2-chloronicotinamide 2-chloro-N-(3- {5-cyclopropyl-1-[(propylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2554 hydroxyphenyl) nicotinamide N-(3-{1-[(benzylarnino) carbonyl]-5-cyclopropyl-lH-pyrazol-3-yl}-4- 2555 hydroxyphenyl)-2-chloronicotinaxnide 2-chloro-N- [3- (5-cyclopropyl-l- { [ (2-phenylethyl) ammo] carbonyl}-lH-pyrazol-3- 2556 yl)-4-hydroxyphenyl] nicotinamide 2-chloro-N- [3- (5-cyclopropyl-l- { [ (2-methylbenzyl) ammo] carbonyl}-lH-pyrazol- 2557 3-yl)-4-hydroxyphenyl] nicotinamide 2-chloro-N- [3- (5-cyctopropyl-1- f [ (3-methylbenzyl) aminocarbonyl}-1H-pyrazol- 2558 3-yl)-4-hydroxyphenyl] nicotinamide 2-chloro-N- [3- (5-cyclopropyl-1- [ (4-methylbenzyl) amino] carbonyl}-1H-pyrazol- 2559 3-yl)-4-hydroxyphenyl] nicotinamide 2559 2-chloro-N- [3- (l- { [ (2-chlorobenzyl) amino] carbonyl}-5-cyclopropyl-lH-pyrazol- 2560 3-yl)-4-hydroxyphenyl] nicotinamide 2-ehloro-N-[3-(5-eyelopropyl-1- {[(4-fluorobenzyl) aminoJearbonyl}-lH-pyrazol- 2561 3-yl)-4-hydroxyphenyl] nicotinamide 2-ehloro-N- [3- (5-cyclopropyl-l- { [ (3, 4-dichlorobenzyl) ammo] carbonyl}-lH- 2562 pyrazol-3-yl)-4-hydroxyphenyl] nicotinamide 2-ehloro-N-[3-(5-eyelopropyl-1-{[(4-methoxybenzyl) arnino] earbonyl}-lH- 2563 pyrazol-3-yl)-4-hydroxyphenyl] nicotinamide N- (3- {1- [ (sec-butylamino) carbonyl]-5-cyclopropyl-1H-pyrazol-3-yl}-4- 2564 hydroxyphenyl)-2-chloronicotinamide 2-chloro-N- [3- (5-cyclopropyl-1- f [ (2-fluorobenzyl) amino] carbonyl}-IH-pyrazol- 2565 3-yl)-4-hydroxyphenyl] nicotinamide 2-chloro-N- [3- (5-cyclopropyl-l- { [ (3-fluorobenzyl) ammo] carbonyl}-lH-pyrazol- 2566 3-yl)-4-hydroxyphenyl] nicotinamide 2-chloro-N-(3- {5-cyclopropyl-1-[(cyclopropylamino) carbonyl]-lH-pyrazol-3-yl}- 2567 4-hydroxyphenyl) nicotinamide 2-chloro-N-(3- {5-cyclobutyl-1-[(isopropylanzino) carbonyl]-1 H-pyrazol-3-yl}-4- 2568 hydroxyphenyl) nicotinamide 2-chloro-N-(3- {5-cyclobutyl-1-[(ethylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2569 hydroxyphenyl) nicotinamide N-(3- {1-[(allylamino) carbonyl]-5-cyclobutyl-lH-pyrazol-3-yl}-4-hydroxyphenyl)- 2570 2-chloronicotinarnide 2-chloro-N-(3- {5-cyclobutyl-1-[(propylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2571 hydroxyphenyl) nicotinamide N-(3- {1-[(benzylamino) carbonyl]-5-cyclobutyl-lH-pyrazol-3-yl}-4- 2572 hydroxyphenyl)-2-chloronicotinamide 2-chloro-N- [3- (5-cyclobutyl-1-1 [ (2-phenylethyl) amino] carbonyl}-IH-pyrazol-3- 2573 yl)-4-hydroxyphenyl] nicotinainide 2-chloro-N- [3- (5-cyclobutyl-1- f [ (2-methylbenzyl) amino] carbonyl}-1H-pyrazo-3- 2574 yl)-4-hydroxyphenyl] nicotinamide 2-chloro-N- [3- (5-cyclobutyl-l- { [ (3-methylbenzyl) ammo] carbonyl}-lH-pyrazol-3- 2575 yl)-4-hydroxyphenyl] nicotinamide 2-chloro-N-[3-(5-cyclobutyl-1- {[(4-methylbenzyl) arnino] carbonyl}-lH-pyrazol-3- 2576 yl)-4-hydroxyphenyl] nicotinamide 2-chloro-N- [3- (I- { [ (2-chlorobenzyl) aminojcarbonyl}-5-cyclobutyl-lH-pyrazol-3- 2577 yl)-4-hydroxyphenyl] nicotinamide 2-chloro-N- [3- (5-cyclobutyl-1- { [ (4-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3- 2578 yl)-4-hydroxyphenyl] nicotinarnide 2-chloro-N- [3- (5-cyclobutyl-l- { [ (3, 4-dichlorobenzyl) amino] carbonyl}-lH- 2579 pyrazol-3-yl)-4-hydroxyphenyl] nicotinamide 2-chloro-N- [3- (5-cyclobutyl-I- f [ (4-methoxybenzyl) amino] carbonyl}-1H-pyrazol- 2580 3-yl)-4-hydroxyphenyl] nicotinamide N- (3- {l- [ (sec-butylamino) carbonyl]-5-cyclobutyl-lH-pyrazol-3-yl}-4- 2581 hydroxyphenyl)-2-chloronicotinamide 2-chloro-N- [3- (5-cyclobutyl-1- { [ (2-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3- 2582 yl)-4-hydroxyphenyl] nicotinamide 2-chloro-N- [3- (5-cyclobutyl-1- f [ (3-fluorobenzyl) amino] carbonyl}-1H-pyrazol-3- 2583 yl)-4-hydroxyphenyl] nicotinamide 2-chloro-N- {5-cyclobutyl-1-[(cyclopropylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2584 hydroxyphenyl) nicotinamide 2-chloro-N-(3- {5-cyclopentyl-1-[(isopropylaxnino) carbonyl]-lH-pyrazol-3-yl}-4- 2585 hydroxyphenyl) nicotinamide 2-chloro-N- {5-cyclopentyl-1-[(ethylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2586 hydroxyphenyl) nicotinamide N-(3- {1-[(allylamino) carbonyl]-5-cyclopentyl-lH-pyrazol-3-yl}-4- 2587 hydroxyphenyl)-2-chloronicotinamide 2-chloro-N- {5-cyclopentyl-1-[(propylainino) carbonyl]-lH-pyrazol-3-yl}-4- 2588 hydroxyphenyl) nicotinamide _ _ N- {1-[(benzylarnino) carbonyl3-5-cyclopentyl-lH-pyrazol-3-yl}-4- 2589 hydroxyphenyl)-2-chloronicotinamide 2-chloro-N- [3- (5-cyclopentyl-l- { [ (2-phenylethyl) a. mino] carbonyl}-lH-pyrazol-3- 2590 yl)-4-hydroxyphenyl] nicotinamide 2-chloro-N- [3- (5-cyclopentyl-1- { [ (2-methylbenzyl) ammo] carbonyl}-IH-pyrazol- 2591 3-yl)-4-hydroxyphenyl] nicotinamide 2-chloro-N- [3- (5-cyclopentyl-1- { [ (3-methylb enzyl) amino] carbonyl}-1 H-pyrazol- 2592 3-yl)-4-hydroxyphenyl] nicotinamide 2-chloro-N- [3- (5-cyclopentyl-1- {[ (4-methylbenzyl) amino] carbonyl}-1H-pyrazol- 2593 3-yl)-4-hydroxyphenyl] nicotinamide 2-chloro-N- [3- (l- { [ (2-chlorobenzyl) amino] carbonyl3-5-cyclopentyl-lH-pyrazol- 2594 3-yl)-4-hydroxyphenyl nicotinamide 2-chloro-N- [3- (5-cyclopemyl-l- { [ (4-fluorobenzyl) amino] carbon. yl}-lH-pyrazol-3- 2595 yl)-4-hydroxyphenyl] nicotinamide 2-chloro-N- [3- (5-cyclopentyl-1- { [ (3, 4-dichlorobenzyl) amino] carbonyl}-1H- 2596 pyrazol-3-yl)-4-hydroxyphenyl] nicotinamide 2-chloro-N- [3- (5-cyclopentyl-1- { [ (4-methoxyb enzyl) amino] carbonyl}-1H- 2597 pyrazol-3-yl)-4-hydroxyphenyl] nicotinamide N- {1-[(sec-butylamino) carbonyl]-5-cyclopentyl-lH-pyrazol-3-yl}-4- 2598 hydroxyDhenyl)-2-chloronicotinamide 2-chloro-N-[3-(5-cyclopentyl-l- {[(2-fluorobenzyl) aminolcarbonyl}-lH-pyrazol-3- 2599 yl)-4-hydroxyphenyl] nicotinamide 2-chloro-N- [3- (5-cyclopentyl- I- { [ (3-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3- 2600 yl)-4-hydroxyphenyl] nicotinamide 2-chloro-N- {5-cyclopentyl-1-[(cyclopropylamino) carbonyl]-lH-pyrazol-3-yl}- 2601 4-hydroxyphenyl) nicotinamide 5-cyclopropyl-3-(2-hydroxy-5- {[4-(trifluoromethoxy) benzoyl] amino} phenyl)-N- 2602 isopropyl-lH-pyrazole-l-carboxamide 5-cyclopropyl-N-ethyl-3- (2-hydroxy-5- { [4- 2603 (trifluoromethoxy) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide N-allyl-5-cyclopropyl-3- (2-hydroxy-5- { [4- 2604 (trifluoromethoxy) benzoyl] amino} phenyl)-1H-pyrazole-1-carboxamide 5-cyclopropyl-3-(2-hydroxy-5- {[4-(trifluoromethoxy) benzoyl] amino} phenyl)-N- 2605 propyl-lH-pyrazole-1-carboxamide N-benzyl-5-cyclopropyl-3-(2-hydroxy-5- {[4- 2606 (trifluoromethoxy) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3-(2-hydroxy-5- {[4-(trifluoromethoxy) benzoyl] amino} phenyl)-N- 2607 (2-phenylethyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3-(2-hydroxy-5- {[4-(trifluoromethoxy) benzoyl] amino} phenyl)-N- 2608 (2-methylbenzyl)-1 H-pyrazole-1-carboxaznide 5-cyclopropyl-3-(2-hydroxy-5- {[4-(trifluoromethoxy) benzoyl] amino} phenyl)-N- 2609 (3-methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- (2-hydroxy-5-f [4- (trifluoromethoxy) benzoyl] amino} phenyl)-N- 2610 (4-methylbenzyl)-1H-yrazole-1-carboxamide N-(2-chlorobenzyl)-5-cyclopropyl-3-(2-hydroxy-5- { [4- 2611 (trifluoromethoxy) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-N- (4-fluorobenzyl)-3- (2-hydroxy-5- { [4- 2612 (trifluoromethoxy) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-N- (3, 4-dichlorobenzyl)-3- (2-hydroxy-5- { [4- 2613 (trifluoromethoxy) benzoyl] amino} phenyl)-1H-pyrazole-1-carboxamide 5-cyclopropyl-3-(2-hydroxy-5- {[4-(trifluoromethoxy) benzoyl] amino} phenyl)-N- 2614 (4-methoxybenzyl)-lH-pyrazole-l-carboxamide N-(sec-butyl)-5-cyclopropyl-3-(2-hydroxy-5- {[4- 2615 (trifluoromethoxy) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-N- (2-fluorobenzyl)-3- (2-hydroxy-5- { [4- 2616 (trifluoromethoxy) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-N-(3-fluorobenzyl)-3-(2-hydroxy-5- {[4- 2617 (trifluoromethoxy) benzoyl] amino} phenyl)-1H-pyrazole-1-carboxamide N, 5-dicyclopropyl-3-(2-hydroxy-5- {[4-(trifluoromethoxy) benzoyl] amino} phenyl)- 2618 IH-pyrazole-l-carboxamide s 5-cyclobutyl-3-(2-hydroxy-5- {[4-(trifluoromethoxy) benzoyl] amino} phenyl)-N- 2619 isopropyl-lH-pyrazole-1-carboxamide x A 5-cyclobutyl-N-ethyl-3- (2-hydroxy-5- { [4- 2620 (trifluoromethoxy) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide N-allyl-5-cyclobutyl-3-(2-hydroxy-5- {[4- 2621 (trifluoromethoxy) benzoyl amino phenyl)-lH-pyrazole-1-carboxamide 5-cyclobutyl-3- (2-hydroxy-5-f [4- (trifluoromethoxy) benzoyl] amino} phenyl)-N- 2622 propyl-lH-pyrazole-1-carboxamide A A A _ N-benzyl-5-cyclobutyl-3-(2-hydroxy-5- {[4- 2623 (trifluoromethoxy) benzoyllamino} Phenyl)-lH-Pyrazole-l-carboxamide S 5-cyclobutyl-3-(2-hydroxy-5- {[4-(trifluoromethoxy) benzoyl] amino} phenyl)-N-(2- 2624 phenylethyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3-(2-hydroxy-5- {[4-(trifluoromethoxy) benzoyl] amino} phenyl)-N-(3- 2625 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3-(2-hydroxy-5- {[4-(trifluoromethoxy) benzoyl] amino} phenyl)-N-(3- 2626 methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3-(2-hydroxy-5- {[4-(trifluoromethoxy) benzoyl] amino} phenyl)-N-(4- 2627 methylbenzyl)-lH-pyrazole-l-carboxamide N- (2-chlorobenzyl)-5-cyclobutyl-3- (2-hydroxy-5- { [4- 2628 (trifluoromethoxy) benzoyl] amino} phenyl)-1 H-pyrazole-1-carboxamide 5-cyclobutyl-N- (4-fluorobenzyl)-3- (2-hydroxy-5- { [4- 2629 (trifluoromethoxy) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-N- (3, 4-dichlorobenzyl)-3- (2-hydroxy-5- { [4- 2630 (trifluoromethoxy) benzoyl] amino} phenyl)-lH-pyrazole-1-carboxamide 5-cyclobutyl-3-(2-hydroxy-5-{[4-(trifluoromethoxy) benzoyl] amino} phenyl)-N-(4- 2631 methoxybenzyl)-lH-pyrazole-l-carboxamide N-(sec-butyl)-5-cyclobutyl-3-(2-hydroxy-5- {[4- 2632 (trifluoromethoxy) benzoyl amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-N- (2-fluorobenzyl)-3- (2-hydroxy-5- { [4- 2633 (trifluoromethoxy) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-N- (3-fluorobenzyl)-3- (2-hydroxy-5- { [4- 2634 (trifluoromethoxy) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-N-cyclopropyl-3- (2-hydroxy-5- { [4- 2635 (trifluoromethoxy) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxam de 5-cyclopentyl-3-(2-hydroxy-5- {[4-(trifluoromethoxy) benzoyl] amino} phenyl)-N- 2636 isopropyl-lH-pyrazole-l-carboxamide 5-cyclopentyl-N-ethyl-3- (2-hydroxy-5-f [4- 2637 (trifluoromethoxy) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide N-allyl-5-cyclopentyl-3- (2-hydroxy-5- { [4- 2638 (trifluoromethoxy) benzoyl] amino phenyl)-1H-pyrazole-l-carboxamide 5-cyclopentyl-3-(2-hydroxy-5- {[4-(trifluoromethoxy) berlzoyl] amino} phenyl)-N- 2639 Pronyl-1} yrazole-1-carboxamide N-benzyl-5-cyclopentyl-3- (2-hydroxy-5- { [4- 2640 (trifluoromethoxy) benzoyllaminoTphenyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3-(2-hydroxy-5- {[4-(trifluoromethoxy) benzoyl] amino} phenyl)-N- 2641 (2-phenylethyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3-(2-hydroxy-5- {[4-(trifluoromethoxy) benzoyl] amino} phenyl)-N- 2642 (2-methylbenzyl)-IH-pyrazole-1-carboxamide 5-cyclopentyl-3-(2-hydroxy-5- {[4-(trifluoromethoxy) benzoyl] aAnino} phenyl)-N- 2643 (3-methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- (2-hydroxy-5- { [4- (trifluoromethoxy) benzoyl] amino} phenyl)-N- 2644 (4-methylbenzyl)-lH-pyrazole-l-carboxamide N- (2-chlorobenzyl)-5-cyclopentyl-3- (2-hydroxy-5- { [4- 2645 (trifluoromethoxy) benzoyl] amino}phenyl)-1H-pyrazole-l-carboxamide 5-cyclopentyl-N- (4-fluorobenzyl)-3- (2-hydroxy-5- {[4- 2646 (trifluoromethoxy) benzoyl] amino}phenyl)-1H-pyrazole-1-carboxamide 5-cyclop entyl-N- (3, 4-dichlorobenzyl)-3- (2-hydroxy-5- { [4- 2647 (trifluoromethoxy) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3-(2-hydroxy-5- {[4-(trifluoromethoxy) benzoyl] amino} phenyl)-N- 2648 (4-methoxybenzyl)-lH-pyrazole-l-carboxamide N-(sec-butyl)-5-cyclopentyl-3-(2-hydroxy-5- {[4- 2649 (trifluoromethoxy) benzoyl] aminophenyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-N-(2-fluorobenzyl)-3-(2-hydroxy-5- {[4- 2650 (trifluoromethoxy) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-N-(3-fluorobenzyl)-3-(2-hydroxy-5- {[4- 2651 (trifluoromethoxy) benzoyl] amino} phenyl)-lH-pyrazole-1-carboxamide 5-cyclopentyl-N-cyclopropyl-3- (2-hydroxy-5- { [4- 2652 (trifluoromethoxy) benzoyl] amino} phenyl)-lH-pyrazole-l-carboxamide N-(3- {5-cyclopropyl-1-[(isopropylamino) carbonyl]-1 H-pyrazol-3-yl}-4- 2653 hydroxyphenyl) isoxazole-5-carboxamide N- (3- {5-cyclopropyl-1- [ (ethylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2654 hydroxyphenyl) isoxazole-5-carboxamide N- (3- {1- [ (allylammo) carbonyl]-5-cyclopropyl-lH-pyrazol-3-yl}-4- 2655 hydroxyphenyl) isoxazole-5-carboxamide A N-(3- {5-cyclopropyl-1-[(propylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2656 hydroxyDhenvl) isoxazole-5-carboxamide N- {1-[(benzylamino) carbonyl]-5-cyclopropyl-lH-pyrazol-3-yl}-4- 2657 hydroxyphenyl) isoxazole-5-carboxarnide N- [3- (5-cyclopropyl-l- { [ (2-phenylethyl) ammo] carbonyl}-lH-pyrazol-3-yl)-4- 2658 hydroxyphenyl] isoxazole-5-carboxamide N- [3- (5-cyclopropyl-l- { [ (2-methylbenzyl) ammo] carbonyl}-lH-pyrazol-3-yl)-4- 2659 hydroxyphenyl] isoxazole-5-carboxamide N- [3- (5-cyclopropyl-l- { [ (3-methylbenzyl) ammo] carbonyl}-lH-pyrazol-3-yl)-4- 2660 hydroxyphenyl] isoxazole-5-carboxamide N- [3- (5-cyclopropyl-1- {[ (4-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2661 hydroxyphenyllisoxazole-5-carboxamide N- [3- (1- f [ (2-chlorobenzyl) amino] carbonyl}-5-cyclopropyl-lH-pyrazol-3-yl)-4- 2662 hydroxyphenyl] isoxazole-5-carboxamide N- [3- (5-cyclopropyl-1- { [ (4-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2663 hydroxyphenyl] isoxazole-5-carboxamide N- [3- (5-cyclopropyl-1- { [ (3, 4-dichlorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)- 2664 4-hydroxyphenyl] isoxazole-5-carboxamide N- [3- (5-cyclopropyl-1- {[ (4-methoxybenzyl) amino] carbonyl}-1H-pyrazol-3-yl)-4- 2665 hydroxynhenyl] isoxazole-5-carboxamide A N- (3- 1- [ (sec-butylamino) carbonyl]-5-cyclopropyl-lH-pyrazol-3-yl}-4- 2666 hydroxyphenyl) isoxazole-5-carboxamide N- [3- (5-cyclopropyl-1- { [ (2-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2667 hydroxyphenyl] isoxazole-5-carboxamide N- [3- (5-cyclopropyl-1- [ (3-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2668 hydroxyphenyl] isoxazole-5-carboxamide N-(3- {5-cyclopropyl-1- [(cyclopropylamino) carbonyl]-1 H-pyrazol-3-yl}-4- 2669 hydroxyphenyl) isoxazole-5-carboxamide N-(3- {5-cyclobutyl-1-[(isopropylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2670 hydroxyphenyl) isoxazole-5-carboxamide N-(3- {5-cyclobutyl-1-[(ethylamino) carbonyl]-1H-pyrazol-3-yl}-4- 2671 hydroxyphenyl) isoxazole-5-carboxamide N- {1-[(allylamino) carbonyl]-5-cyclobutyl-lH-pyrazol-3-yl}-4- 2672 hydroxyphenyl) isoxazole-5-carboxamide N-(3- {5-cyclobutyl-1-[(propylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2673 hydroxyphenyl) isoxazole-5-carboxamide N- {1-[(benzylamino) carbonyl]-5-cyclobutyl-lH-pyrazol-3-yl}-4- 2674 hydroxyphenyl) isoxazole-5-carboxamide N- [3- (5-cyclobutyl-1- { [ (2-phenylethyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2675 hydroxyphenyl] isoxazole-5-carboxamide N- [3- (5-cyclobutyl-l- { [ (2-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2676 hydroxyDhenyllisoxazole-5-carboxamide A 0 N- [3- (5-cyclobutyl-l- { [ (3-methylbenzyl) amino] carbonyll-lH-pyrazol-3-yl)-4- 2677 hydroxyphenyl] isoxazole-5-carboxamide N- [3- (5-cyclobutyl-1- { [ (4-methylbenzyl) amino] carbonyl}-1 H-pyrazol-3-yl)-4- 2678 hydroxyphenyl] isoxazole-5-carboxamide N- [3- (l- { [ (2-chlorobenzyl) amino] carbonyl}-5-cyclobutyl-lH-pyrazol-3-yl)-4- 2679 hydroxyphenyl] isoxazole-5-carboxamide N- [3- (5-cyclobutyl-1- { [ (4-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2680 hydroxyphenyl] isoxazole-5-carboxamide N- [3- (5-cyclobutyl-1- { [ (3, 4-dichlorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2681 hydroxyphenyl] isoxazole-5-carboxamide N- [3- (5-cyclobutyl-l- { [ (4-methoxybenzyI) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2682 hydroxyPhenyllisoxazole-5-carboxamide J N- (3- f 1- [ (sec-butylamino) carbonyl]-5-cyclobutyl-lH-pyrazol-3-yl}-4- 2683 hydroxyphenyl) isoxazole-5-carboxamide J N- [3- (5-cyclobutyl-1- { [ (2-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2684 hydroxyphenyl] isoxazole-5-carboxamide N- [3- (5-cyclobutyl-1- [ (3-fluorobenzyl) amino] carbonyl-1H-pyrazol-3-yl)-4- 2685 hydroxyphenyl] isoxazole-5-carboxamide N- (3-15-cyclobutyl-l- [ (cyclopropylamino) carbonyl]-lH-pyrazol-3-yl}-4- 2686 hydroxyphenyl) isoxazole-5-carboxamide N-(3- {5-cyclopentyl-1-[(isopropylarnino) carbonyl]-lH-pyrazol-3-yl}-4- 2687 hydroxyphenyl) isoxazole-5-carboxamide N-(3- {5-cyclopentyl-1-[(ethylamino) carbonyl]-1H-pyrazol-3-yl}-4- 2688 hydroxyphenyl) isoxazole-5-carboxamide N- {1-[(allylarnino) carbonyl]-5-cyclopentyl-lH-pyrazol-3-yl}-4- 2689 hydroxyphenyl) isoxazole-5-carboxamide N- (3- {5-cyclopentyl-1- [ (propylamino) carbonyl]-1H-pyrazol-3-yl}-4- 2690 hydroxyphenyl) isoXazole-5-carboxamide N- (3-f 1- [ (benzylamino) carbonyl]-5-cyclopentyl-lH-pyrazol-3-yl)-4- 2691 hydroxyphenyl) isoxazole-5-carboxamide N- [3- (5-cyclopentyl-l- { [ (2-phenylethyl) ammo] carbonyl}-lH-pyrazol-3-yl)-4- 2692 hydroxyphenyl] isoxazole-5-carboxamide N- [3- (5-cyclopentyl-1- { [ (2-methylbenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2693 hydroxyphenyl] isoxazole-5-carboxamide N- [3- (5-cyclopentyl-I-1 [ (3-methylbenzyl) aminolcarbonyll-IH-pyrazol-3-yl)-4- 2694 hydroxyphenyl] isoxazole-5-carboxamide ffi N- [3- (5-cyclopentyl-1-1 [ (4-methylbenzyl) amino] carbonyll-IH-pyrazol-3-yl)-4- 2695 hydroxyphenyl] isoxazole-5-carboxamide N- [3- (1- f [ (2-chlorobenzyl) amino] carbonyl}-5-cyclopentyl-lH-pyrazol-3-yl)-4- 2696 hydroxyphenyl] isoxazole-5-carboxamide N- [3- (5-cyclopentyl-1-1 [ (4-fluorobenzyl) aminolcarbonyll-IH-pyrazol-3-yl)-4- 2697 hydroxyphenyl] isoxazole-5-carboxamide N- [3- (5-cyclopentyl-1-1 [ (3, 4-dichlorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)- 2698 4-hydroxyphenyl] isoxazole-5-carboxamide N- [3- (5-cyclopentyl-l- { [ (4-methoxybenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2699 hydroxyphenyl] isoxazole-5-carboxamide N-(3- {1-[(sec-butylamino) carbonyl]-5-cyclopentyl-lH-pyrazol-3-yl}-4- hydroxyphenyl) isoxazole-5-carboxamide N- [3- (5-cyclopentyl-l-f [ (2-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2701 hydroxyphenyl] isoxazole-5-carboxamide N- [3- (5-cyclopentyl-1- [ (3-fluorobenzyl) amino] carbonyl}-lH-pyrazol-3-yl)-4- 2702 hydroxyphenyl] isoxazole-5-carboxamide N-(3- {5-cyclopentyl-1-[(cyclopropylamino) carbonyl3-lH-pyrazol-3-yl}-4- 2703 hydroxyphenyl) isoxazole-5-carboxamide 5-cyclopropyl-3-(2-hydroxy-5- {[(1-methyl-lH-pyrrol-2- 2704 yl) carbonyl] amino} phenyl)-N-isopropyl-1H-pyrazole-1-carboxamide 5-cyclopropyl-N-ethyl-3- (2-hydroxy-5- {[ (1-methyl-lH-pyrrol-2- 2705 yl) carbonyl] amino}phenyl)-lH-pyrazole-l-carboxamide N-allyl-5-cyclopropyl-3-(2-hydroxy-5-{[(1-methyl-lH-pyrrol-2 - 2706 yl) carbonyl] amino}phenyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3-(2-hydroxy-5- {[(1-methyl-lH-pyrrol-2- 2707 yl) carbonylgamino} phenyl)-N-propyl-lH-pyrazole-l-carboxamide N-benzyl-5-cyclopropyl-3-(2-hydroxy-5- {[(1-methyl-lH-pyrrol-2- 2708 yl) carbonyl amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- (2-hydroxy-5-f [ (I-methyl-IH-pyrrol-2- 2709 yl) carbonyl] amino} phenyl)-N- (2-phenylethyl)-lH-pyrazole-1-carboxamide 5-cyclopropyl-3-(2-hydroxy-5- {[(l-methyl-lH-pyrrol-2- 2710 yl) carbonyl] amino} phenyl)-N- (2-methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3-(2-hydroxy-5- {[(1-methyl-lH-pyrrol-2- 2711 yl) carbonyl] amino} phenyl)-N-(3-methylbenzyl)-lH-pyrazole-1-carboxamide 5-cyclopropyl-3-(2-hydroxy-5- {[(1-methyl-lH-pyrrol-2- 2712 yl) carbonyl] amino phenyl)-N- (4-methylbenzyl)-lH-pyrazole-1-carboxamide N- (2-chlorobenzyl)-5-cyclopropyl-3- (2-hydroxy-5- { [ (1-methyl-1 H-pyrrol-2- 2713 yl) carbonyl] amino} phenyl)-1 H-pyrazole-1-carboxamide 5-cyclopropyl-N-(4-fluorobenzyl)-3-(2-hydroxy-5- { [(1-methyl-1 H-pyrrol-2- 2714 yl) carbonyllamino Tphenyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-N-(3, 4-dichlorobenzyl)-3-(2-hydroxy-5- {[(1-methyl-lH-pyrrol-2- 2715 yl) carbonyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopropyl-3- (2-hydroxy-5- { [ (1-methyl-1 H-pyrrol-2- 2716 yl) carbonyl] arnino} phenyl)-N-(4-methoxybenzyl)-lH-pyrazole-l-carboxamide N- (sec-butyl)-5-cyclopropyl-3- (2-hydroxy-5- { [ (1-methyl-1 H-pyrrol-2- 2717 yl) carbonyl] amino henyl)-lH-pyrazole-1-carboxamide 5-cyclopropyl-N- (2-fluorobenzyl)-3- (2-hydroxy-5- { [ (1-methyl-1 H-pyrrol-2- 2718 yl) carbonyl] amino} phenyl)-lH-pyrazole-1-carboxamide 5-cyclopropyl-N- (3-fluorobenzyl)-3- (2-hydroxy-5- { [ (l-methyl-1 H-pyrrol-2- 2719 yl) carbonyl] phenyl)-lH-pyrazole-l-carboxamide N, 5-dicyclopropyl-3-(2-hydroxy-5- {[(1-methyl-lH-pyrrol-2- 2720 yl) carbonyllamino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- (2-hydroxy-5- { [ (l-mcthyl-lH-pyn-ol-2- 2721 yl) carbonyl] amino} phenyl)-N-isopropyl-1 H-pyrazole-1-carboxamide 5-cyclobutyl-N-ethyl-3- (2-hydroxy-5- { [ (l-methyl-lH-pyrrol-2- 2722 yl) carbonyl] amino} phenyl)-lH-pyrazole-l-carboxamide N-allyl-5-cyclobutyl-3-(2-hydroxy-5- { [(1-methyl-lH-pyrrol-2- 2723 yl) carbonyl] amino phenyl)-1H-pyrazole-1-carboxamide 5-cyclobutyl-3-(2-hydroxy-5- { [(1-methyl-1 H-pyrrol-2- 2724 yl) carbonyl] amino} phenyl)-N-propyl-1H-pyrazole-1-carboxamide N-benzyl-5-cyclobutyl-3- (2-hydroxy-5- {[ (1-methyl-lH-pyrrol-2- 2725 yl) carbonyl] aminophenyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3-(2-hydroxy-5- { [(1-methyl-1 H-pyrrol-2- 2726 yl) carbonyl) amino phenyl-N-2-henylethyl-1H-yrazole-1-carboxamide 5-cyclobutyl-3- (2-hydroxy-5- { [ (l-methyl-lH-pyrrol-2- 2727 yl) carbonyl] arnino} phenyl)-N-(2-methylbenzyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3- (2-hydroxy-5- {[ (1-methyl-lH-pyrrol-2- 2728 yl) carbonyl] amino} phenyl)-N- (3-methylbenzyl)-lH-pyrazole-1-carboxamide 5-cyclobutyl-3-(2-hydroxy-5- {[(1-methyl-lH-pyrrol-2- 2729 yl) carbonyl] amino} phenyl)-N- (4-methylbenzyl)-lH-pyrazole-1-carboxamide N-(2-chlorobenzyl)-5-cyclobutyl-3-(2-hydroxy-5- {[(1-methyl-lH-pyrrol-2- 2730 yl) carbonyl] amino phenyl)-lH-pyrazole-1-carboxamide 5-cyclobutyl-N-(4-fluorobenzyl)-3-(2-hydroxy-5-{[(1-methyl-l H-pyrrol-2- 2731 yl) carbonyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-N-(3, 4-dichlorobenzyl)-3-(2-hydroxy-5- {[(1-methyl-lH-pyrrol-2- 2732 yl) carbonyl] amino henyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-3-(2-hydroxy-5- { [ (1-methyl-1 H-pyrrol-2- 2733 yl) carbonyl] amino} phenyl)-N- (4-methoxybenzyl)-lH-pyrazole-l-carboxamide N- (sec-butyl)-5-cyclobutyl-3- (2-hydroxy-5-1 [ (l-methyl-lH-pyrrol-2- 2734 yl) carbonyl] amino} phenyl)-lH-yrazole-l-carboxamide 5-cyclobutyl-N- (2-fluorobenzyl)-3- (2-hydroxy-5- { [ (1-methyl-lH-pyrrol-2- 2735 yl) carbonyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-N-(3-fluorobenzyl)-3-(2-hydroxy-5- { [(1-methyl-1 H-pyrrol-2- 2736 yl) carbonyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclobutyl-N-cyclopropyl-3-(2-hydroxy-5- {[(1-methyl-llI-pyrrol-2- 2737 yl) carbonyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3- (2-hydroxy-5- { [ (1-methyl-1 H-pyrrol-2- 2738 yl) carbonyl] amino} phenyl)-N-isopropyl-lH-pyrazole-l-carboxamide 5-cyclopentyl-N-ethyl-3-(2-hydroxy-5- {[(1-methyl-lH-pyrrol-2- 2739 yl) carbonyl] amino henyl)-lH-pyrazole-l-carboxamide N-allyl-5-cyclopentyl-3-(2-hydroxy-5- {[(1-methyl-lH-pyrrol-2- 2740 yl) carbonyl amino phenyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3-(2-hydroxy-5- {[(1-methyl-lH-pyrrol-2- 2741 yl) carbonyl] amino} phenyl)-N-propyl-1 H-pyrazole-1-carboxamide N-benzyl-5-cyclopentyl-3- (2-hydroxy-5- f [ (1-methyl-IH-pyrrol-2- 2742 yl) carbonyl] amino} phenyl)-lH-pyrazole-1-carboxamide . 5-cyclopentyl-3-(2-hydroxy-5- {[(1-methyl-lH-pyrrol-2- 2743 yl) carbonyl] aminophenyl)-N- (2-phenylethyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3-(2-hydroxy-5- {[(1-methyl-lH-pyrrol-2- 2744 yl) carbonyl] amino} phenyl)-N-(2-methylbenzyl)-lH-pyrazole-1-carboxamide 5-cyclopentyl-3- (2-hydroxy-5- f [ (1-methyl-1H-pyrrol-2- 2745 yl) carbonyllamino} » henyl)-N-(3-methylbenzyl)-lH-pyrazole-1-carboxamide 5-cyclopentyl-3-(2-hydroxy-5- {[(1-methyl-lH-pyrrol-2- 2746 yl) carbonyl3amino} phenyl)-N-(4-methylbenzyl)-IH-pyrazole-l-carboxamide N- (2-chlorobenzyl)-5-cyclopentyl-3- (2-hydroxy-5- { [ (1-methyl-1H-pyrrol-2- 2747 yl) carbonyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-N-(4-fluorobenzyl)-3-(2-hydroxy-5- {[(1-methyl-lH-pytrol-2- 2748 yl) carbonyl] amino} phenyl)-lH-pyrazole-1-carboxamide 5-cyclopentyl-N- (3, 4-dichlorobenzyl)-3- (2-hydroxy-5- { [ (1-methyl-lH-pyrrol-2- 2749 yl) carbonyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-3-(2-hydroxy-5- {[(1-methyl-lH-pyrrol-2- 2750 yl) carbonyl] amino henyl)-N- (4-methoxybenzyl)-lH-pyrazole-l-carboxamide N- (sec-butyl)-5-cyclopentyl-3- (2-hydroxy-5- { [ (1-methyl-1H-pyrrol-2- 2751 yl) carbonyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-N-(2-fluorobenzyl)-3-(2-hydroxy-5- {[(1-methyl-lH-pyirol-2- 2752 yl) carbonyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-N-(3-fluorobenzyl)-3-(2-hydroxy-5- {[(1-methyl-lH-pyrrol-2- 2753 yl) carbonyl] amino} phenyl)-lH-pyrazole-l-carboxamide 5-cyclopentyl-N-cyclopropyl-3- (2-hydroxy-5- { [ (1-methyl-1H-pyrrol-2- 2754 yl) carbonyl] amino} phenyl)-lH-pyrazole-l-carboxamide