Title:
IDENTIFICATION OF OLEANOLIC ACID AND PLANT EXTRACT FOR GLUCOSE-6-PHOSPHATE DEHYDROGENASE-RELATED DISORDERS INCLUDING BAG3OPATHY
Document Type and Number:
WIPO Patent Application WO/2024/078517
Kind Code:
A1
Abstract:
A method of treating a glucose-6-phosphate dehydrogenase deregulated disorder in a subject in need thereof, the method involving administering a therapeutically effective amount of oleanolic acid or a conjugate salt thereof or prodrug thereof to the subject. The glucose-6-phosphate dehydrogenase deregulated disorder can be BCL2 associated athanogene myofibrillar myopathy, amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, or Alzheimer disease.
Inventors:
BIAN ZHAOXIANG (CN)
HUNG TAO (CN)
ZHAO LING (CN)
ZHONG LIDAN (CN)
LIN CHENGYUAN (CN)
HUNG TAO (CN)
ZHAO LING (CN)
ZHONG LIDAN (CN)
LIN CHENGYUAN (CN)
Application Number:
PCT/CN2023/123896
Publication Date:
April 18, 2024
Filing Date:
October 11, 2023
Export Citation:
Assignee:
UNIV HONG KONG BAPTIST UNIV (CN)
International Classes:
A61K31/56; A61P21/00; A61P25/16; A61P25/28
Domestic Patent References:
| WO2014122621A2 | 2014-08-14 |
Foreign References:
| JP2000247993A | 2000-09-12 | |||
| CN102229638A | 2011-11-02 | |||
| KR20220101386A | 2022-07-19 | |||
| KR20180105290A | 2018-09-28 | |||
| CN107501381A | 2017-12-22 |
Attorney, Agent or Firm:
BEIJING PAT SF INTELLECTUAL PROPERTY AGENCY CO. LTD (CN)
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