Title:
IgG-BINDING PEPTIDE AND METHOD FOR DETECTING AND PURIFYING IgG USING SAME
Document Type and Number:
WIPO Patent Application WO/2013/027796
Kind Code:
A1
Abstract:
Provided is a peptide capable of binding to human IgG specifically or selectively. A peptide characterized by comprising an amino acid sequence represented by formula (I): (X1-3)-C-(X2)-H-R-G-(Xaa1)-L-V-W-C-(X1-3) (wherein Xs independently represent an arbitrary amino acid residue other than a cysteine residue; C represents a cysteine residue; H represents a histidine residue; R represents an arginine residue; G represents a glycine residue; Xaa1 represents a glutamic acid residue or an asparagine residue; L represents a leucine residue; V represents a valine residue; and W represents a tryptophan residue) and composed of 13-17 amino acid residues, and also characterized by being capable of binding to human IgG.
Inventors:
ITO YUJI (JP)
Application Number:
PCT/JP2012/071303
Publication Date:
February 28, 2013
Filing Date:
August 23, 2012
Export Citation:
Assignee:
OTSUKA CHEMICAL CO LTD (JP)
UNIV KAGOSHIMA (JP)
ITO YUJI (JP)
UNIV KAGOSHIMA (JP)
ITO YUJI (JP)
International Classes:
C12N15/09; C07K1/16; C07K7/08; C07K17/00; C07K19/00; G01N30/88; G01N33/53
Domestic Patent References:
| WO2008054030A1 | 2008-05-08 | |||
| WO2001002001A1 | 2001-01-11 | |||
| WO2001045746A2 | 2001-06-28 | |||
| WO2002086070A2 | 2002-10-31 | |||
| WO2002038592A2 | 2002-05-16 |
Foreign References:
| US20040087765A1 | 2004-05-06 | |||
| JP2003518075A | 2003-06-03 | |||
| JP2003505108A | 2003-02-12 | |||
| JP2011182539A | 2011-09-15 |
Other References:
SAKAMOTO K ET AL.: "Discovery and characterization of a peptide motif that specifically recognizes a non-native conformation of human IgG induced by acidic pH conditions", J. BIOL. CHEM., vol. 284, no. 15, 2009, pages 9986 - 9993, XP002547442
ITO Y ET AL.: "Human IgG-specific binding peptides to distinguish normal and abnormal conformers: Applications for IgG purification and detection", PEPTIDE SCIENCE, vol. 14, no. ISS. 8, 2008, pages 141, XP055153290
TAKAAKI HATANAKA ET AL.: "IgG Tokuiteki Ketsugo Peptide o Mochiita Hito Kessei kara no Kotai Seiseiho no Kento", DAI 10 KAI ANNUAL MEETING OF THE PROTEIN SCIENCE SOCIETY OF JAPAN PROGRAM YOSHISHU, 15 May 2010 (2010-05-15), pages 136, XP008173666
YUJI ITO ET AL.: "Molecular Designs of Antibodies and Peptides by Phage Display", BIOPHYSICS, vol. 48, no. 5, 2008, pages 294 - 298, XP055153848
EY, P. L.; PROWSE, S. J.; JENKIN, C. R., IMMUNOCHEMISTRY, vol. 15, no. 7, 1978, pages 429 - 436
AKERSTROM, B.; BRODIN, T.; REIS, K.; BJORCK, L., J IMMUNOL, vol. 135, no. 4, 1985, pages 2589 - 2592
FASSINA, G.; VERDOLIVA, A.; ODIERNA, M. R.; RUVO, M.; CASSINI, G., J MOL RECOGNIT, vol. 9, no. 5-6, 1996, pages 564 - 569
FASSINA, G.; PALOMBO, G.; VERDOLIVA, A.; RUVO, M.: "The Protein Protocols Handbook", 2002, HUMANA PRESS INC., article "Affinity Purification of Immunoglobulins Using Protein A Mimetic (PAM"
LI, R.; DOWD, V.; STEWART, D. J.; BURTON, S. J.; LOWE, C. R., NATURE BIOTECHNOLOGY, vol. 16, no. 2, 1998, pages 190 - 195
SAKAMOTO, K.; ITO, Y.; HATANAKA, T.; SONI, P. B.; MORI, T.; SUGIMURA, K., THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 284, no. 15, 2009, pages 9986 - 9993
KELLEY ET AL.: "Genetics Engineering Principles and Methods", vol. 12, 1990, PLENUM PRESS, pages: 1 - 19
S TEWART ET AL.: "Solid-Phase Peptide Synthesis", 1989, W. H. FREEMAN CO.
HOUGHTEN, PROC. NATL. ACAD. SCI. USA, vol. 82, 1985, pages 5132
"Shin- seikagakujikken kouza 1, tanpakushitsu IV", 1992, TOKYO KAGAKU DOJIN
J. BIOL. CHEM., vol. 284, 2009, pages 9986
ITO Y ET AL.: "Human IgG-specific binding peptides to distinguish normal and abnormal conformers: Applications for IgG purification and detection", PEPTIDE SCIENCE, vol. 14, no. ISS. 8, 2008, pages 141, XP055153290
TAKAAKI HATANAKA ET AL.: "IgG Tokuiteki Ketsugo Peptide o Mochiita Hito Kessei kara no Kotai Seiseiho no Kento", DAI 10 KAI ANNUAL MEETING OF THE PROTEIN SCIENCE SOCIETY OF JAPAN PROGRAM YOSHISHU, 15 May 2010 (2010-05-15), pages 136, XP008173666
YUJI ITO ET AL.: "Molecular Designs of Antibodies and Peptides by Phage Display", BIOPHYSICS, vol. 48, no. 5, 2008, pages 294 - 298, XP055153848
EY, P. L.; PROWSE, S. J.; JENKIN, C. R., IMMUNOCHEMISTRY, vol. 15, no. 7, 1978, pages 429 - 436
AKERSTROM, B.; BRODIN, T.; REIS, K.; BJORCK, L., J IMMUNOL, vol. 135, no. 4, 1985, pages 2589 - 2592
FASSINA, G.; VERDOLIVA, A.; ODIERNA, M. R.; RUVO, M.; CASSINI, G., J MOL RECOGNIT, vol. 9, no. 5-6, 1996, pages 564 - 569
FASSINA, G.; PALOMBO, G.; VERDOLIVA, A.; RUVO, M.: "The Protein Protocols Handbook", 2002, HUMANA PRESS INC., article "Affinity Purification of Immunoglobulins Using Protein A Mimetic (PAM"
LI, R.; DOWD, V.; STEWART, D. J.; BURTON, S. J.; LOWE, C. R., NATURE BIOTECHNOLOGY, vol. 16, no. 2, 1998, pages 190 - 195
SAKAMOTO, K.; ITO, Y.; HATANAKA, T.; SONI, P. B.; MORI, T.; SUGIMURA, K., THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 284, no. 15, 2009, pages 9986 - 9993
KELLEY ET AL.: "Genetics Engineering Principles and Methods", vol. 12, 1990, PLENUM PRESS, pages: 1 - 19
S TEWART ET AL.: "Solid-Phase Peptide Synthesis", 1989, W. H. FREEMAN CO.
HOUGHTEN, PROC. NATL. ACAD. SCI. USA, vol. 82, 1985, pages 5132
"Shin- seikagakujikken kouza 1, tanpakushitsu IV", 1992, TOKYO KAGAKU DOJIN
J. BIOL. CHEM., vol. 284, 2009, pages 9986
Attorney, Agent or Firm:
HIRAKI Yusuke et al. (JP)
Yusuke Hiraki (JP)
Yusuke Hiraki (JP)
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