Title:
IL10RA BINDING MOLECULES AND METHODS OF USE
Document Type and Number:
WIPO Patent Application WO/2022/031885
Kind Code:
A3
Abstract:
The present disclosure relates to biologically active molecules comprising a single domain antibody (sdAb) that specifically binds to the extracellular domain of human IL10Ra, compositions comprising such antibodies, and methods of use thereof.
Inventors:
VIVONA SANDRO (US)
KASTELEIN ROBERT (US)
ROKKAM DEEPTI (US)
LUPARDUS PATRICK (US)
KASTELEIN ROBERT (US)
ROKKAM DEEPTI (US)
LUPARDUS PATRICK (US)
Application Number:
PCT/US2021/044603
Publication Date:
March 10, 2022
Filing Date:
August 05, 2021
Export Citation:
Assignee:
SYNTHEKINE INC (US)
VIVONA SANDRO (US)
VIVONA SANDRO (US)
International Classes:
C07K14/54; A61K39/00; C07K14/705
Foreign References:
| US20200087624A1 | 2020-03-19 | |||
| US20200071716A1 | 2020-03-05 | |||
| US20200148772A1 | 2020-05-14 |
Other References:
JIANG, H ET AL.: "Regulation of Interleukin-10 Receptor Ubiquitination and Stability byBeta-TrCP-Containing Ubiquitin E3 Ligase", PLOS ONE, vol. 6, no. 11, 8 November 2011 (2011-11-08), pages 1 - 14, XP055168815, DOI: 10.1371/journal.pone.0027464
Attorney, Agent or Firm:
HINSCH, Matthew, E. et al. (US)
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