IMAGING OF MICROARRAYS USING FIBER OPTIC EXCITER

Title:

IMAGING OF MICROARRAYS USING FIBER OPTIC EXCITER

Document Type and Number:

WIPO Patent Application WO2003027724

Kind Code:

A3

Abstract:

Microarrays (11) are imaged by an illumination and detection system that supplies excitation light through one or more optical fibers (20), each fiber transmitting excitation light from an excitation light source (14) to a single spot (12) in the microarray (11). Emission light from each spot is then collected by a collimating lens (15) and converted to a signal that is compiled by conventional software into an image of the entire microarray (11). The optical fiber(s) (20) and the collimating lens (15) are arranged such that the direction of travel of the excitation light (14) and the direction along which the emission light is collected are not coaxial, and preferably both are at an acute angle to the axis normal to the plane of the microarray.

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Inventors:

NAGHIEH HARRY R
HILLENDAHL JAMES W
WALDBESER DAVID E

Application Number:

PCT/US2002/030292

Publication Date:

December 04, 2003

Filing Date:

September 24, 2002

Export Citation:

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Assignee:

BIO RAD LABORATORIES (US)

International Classes:

G01N21/25; G01N21/64; H04N1/04; (IPC1-7): G02B6/26

Foreign References:

US6512618B1	2003-01-28
US4278327A	1981-07-14

Other References: