Title:
IMATINIB DICHLOROACETATE AND ANTI-CANCER AGENT COMPRISING THE SAME
Document Type and Number:
WIPO Patent Application WO/2011/081408
Kind Code:
A2
Abstract:
The present invention relates to imatinib dichloroacetate and an anti-cancer agent comprising the same. The imatinib dichloroacetate of the present invention can inhibit tyrosine kinase as well as induce cancer cells to kill themselves via apoptosis, thereby inhibit growth of cancer cells and lead to their destruction, and show significantly enhanced anti-cancer effects by synergy between imatinib and dichloroacetic acid.
Inventors:
KIM KYOUNG SOO
PARK YOUNG JUN
SONG HYUN-NAM
KIM JOON WOO
PARK YOUNG JUN
SONG HYUN-NAM
KIM JOON WOO
Application Number:
PCT/KR2010/009423
Publication Date:
July 07, 2011
Filing Date:
December 28, 2010
Export Citation:
Assignee:
CELLTRION CHEMICAL RES INST
CELLTRION PHARM INC
KIM KYOUNG SOO
PARK YOUNG JUN
SONG HYUN-NAM
KIM JOON WOO
CELLTRION PHARM INC
KIM KYOUNG SOO
PARK YOUNG JUN
SONG HYUN-NAM
KIM JOON WOO
International Classes:
A61K31/496; C07D403/14; A61P35/00; C07D403/02
Foreign References:
| KR100799821B1 | 2008-01-31 | |||
| KR20080044841A | 2008-05-21 |
Other References:
See references of EP 2519518A4
Attorney, Agent or Firm:
YU, Su Mi (Eunseong Bldg.601-18 Yeoksam-dong,Gangnam-gu, Seoul 135-080, KR)
Download PDF: