IMIDAZOPYRIDIN-2-ONE DERIVATIVE - DAIICHI SANKYO CO LTD

Title:

IMIDAZOPYRIDIN-2-ONE DERIVATIVE

Document Type and Number:

WIPO Patent Application WO/2011/096490

Kind Code:

A1

Abstract:

Disclosed is a prophylactic and/or therapeutic agent for rejection after transplant surgery and for diseases caused by immune system abnormalities, comprising a compound represented by formula (I) or a pharmacologically acceptable salt thereof. In general formula (I), A represents a 8- to 10-membered partially saturated or aromatic fused bicycylic nitrogen-containing heterocyclic group having 1 to 3 nitrogen atoms; A may have the same or different n R1's as substituents; n represents an integer of 0 to 3; B represents a 3- to 7-membered saturated or partially saturated monocyclic hydrocarbon group and may contain 1 or 2 oxygen atoms, sulfur atoms, nitrogen atoms, sulfinyl groups or sulfonyl groups as ring constituents; B may have the same or different m R2's as substituents; R2 represents a substituent present on a carbon atom or a nitrogen atom which forms B; and Q represents a bond or a C1-4 alkylene group.

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Inventors:

OHTSUKA MASAMI
HAGINOYA NORIYASU
ICHIKAWA MASANORI
MATSUNAGA HIRONORI
SAITO HIRONAO
SHIBATA YOSHIHIRO
TSUNEMI TOMOYUKI

Application Number:

PCT/JP2011/052278

Publication Date:

August 11, 2011

Filing Date:

February 03, 2011

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Assignee:

DAIICHI SANKYO CO LTD (JP)
OHTSUKA MASAMI
HAGINOYA NORIYASU
ICHIKAWA MASANORI
MATSUNAGA HIRONORI
SAITO HIRONAO
SHIBATA YOSHIHIRO
TSUNEMI TOMOYUKI

International Classes:

C07D471/04; A61K31/437; A61P1/04; A61P1/16; A61P3/10; A61P5/00; A61P7/00; A61P7/06; A61P11/00; A61P11/02; A61P13/00; A61P13/12; A61P15/00; A61P17/00; A61P17/04; A61P17/06; A61P19/02; A61P21/00; A61P21/04; A61P25/00; A61P27/02; A61P37/06; A61P37/08; A61P43/00; C07D519/00

Domestic Patent References:

WO2008051493A2	2008-05-02
WO2006108103A1	2006-10-12
WO2010008777A2	2010-01-21

Foreign References:

US20080119496A1

2008-05-22

Attorney, Agent or Firm:

ISHIBASHI, Koki et al. (JP)
Kimiki Ishibashi (JP)

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Claims:

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