Title:
IMIDAZOPYRIDINE DERIVATIVE COMPOUNDS AND USE OF SAME
Document Type and Number:
WIPO Patent Application WO/2020/159285
Kind Code:
A1
Abstract:
One aspect of the present invention provides a compound selected from among a compound of chemical formula 1 having lysine-specific demethylase-1 (LSD1) inhibitory activity, and a tautomer, a stereoisomer, and a solvate thereof, and pharmaceutically acceptable salts of the aforementioned components, and said compound is effective in the prevention or treatment of diseases caused by abnormal activation of LSD1.
Inventors:
BAE IN HWAN (KR)
KIM WON JEOUNG (KR)
KIM JI SOOK (KR)
SONG JI YOUNG (KR)
CHOI JAE YUL (KR)
KIM MIN JEONG (KR)
NAM JUNG SOO (KR)
AHN YOUNG GIL (KR)
KIM WON JEOUNG (KR)
KIM JI SOOK (KR)
SONG JI YOUNG (KR)
CHOI JAE YUL (KR)
KIM MIN JEONG (KR)
NAM JUNG SOO (KR)
AHN YOUNG GIL (KR)
Application Number:
PCT/KR2020/001491
Publication Date:
August 06, 2020
Filing Date:
January 31, 2020
Export Citation:
Assignee:
HANMI PHARM IND CO LTD (KR)
International Classes:
C07D471/04; A61K31/4545; A61P35/00
Domestic Patent References:
| WO2012177852A1 | 2012-12-27 | |||
| WO2016014674A1 | 2016-01-28 | |||
| WO2013116291A1 | 2013-08-08 | |||
| WO2016007722A1 | 2016-01-14 | |||
| WO2012135113A2 | 2012-10-04 |
Foreign References:
| US20170369487A1 | 2017-12-28 | |||
| US20060035921A1 | 2006-02-16 |
Other References:
SHI, Y. ET AL.: "Histone demethylation mediated by the nuclear amine oxidase homolog LSD1", CELL, vol. 119, no. 7, 2004, pages 941 - 53, XP002321632, DOI: 10.1016/j.cell.2004.12.012
CELL, vol. 119, no. 7, 2004, pages 941 - 953
CELL, vol. 119, no. 7, 2004, pages 941 - 953
Attorney, Agent or Firm:
Y.P.LEE, MOCK & PARTNERS (KR)
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