Title:
IMMUNE ADJUVANT
Document Type and Number:
WIPO Patent Application WO/2012/014978
Kind Code:
A1
Abstract:
Provided is an immune adjuvant which comprises an active ingredient derived from a naturally occurring material and has an excellent effect.
The immune adjuvant contains, as an active ingredient, a culture composition produced from a culture of a microorganism belonging to the genus Aureobasidium sp. This immune adjuvant can improve the capability of producing an antibody against an antigen and can also improve the immunological effect of an immunogenic substance such as a vaccine.
Inventors:
MORIYA NAOYUKI (JP)
MORIYA YUKIKO (JP)
MIYAZAKI TADAAKI
FUTAGAWA YASUHIRO (JP)
AOKI SHIHO (JP)
MORIYA YUKIKO (JP)
MIYAZAKI TADAAKI
FUTAGAWA YASUHIRO (JP)
AOKI SHIHO (JP)
Application Number:
PCT/JP2011/067262
Publication Date:
February 02, 2012
Filing Date:
July 28, 2011
Export Citation:
Assignee:
UNIV HOKKAIDO NAT UNIV CORP (JP)
AUREO CO LTD (JP)
AUREO SCIENCE CO LTD (JP)
MORIYA NAOYUKI (JP)
MORIYA YUKIKO (JP)
MIYAZAKI TADAAKI
FUTAGAWA YASUHIRO (JP)
AOKI SHIHO (JP)
AUREO CO LTD (JP)
AUREO SCIENCE CO LTD (JP)
MORIYA NAOYUKI (JP)
MORIYA YUKIKO (JP)
MIYAZAKI TADAAKI
FUTAGAWA YASUHIRO (JP)
AOKI SHIHO (JP)
International Classes:
A61K39/145; A61K36/06; A61P31/16; A61P37/04
Foreign References:
| JP2002204687A | 2002-07-23 | |||
| JP2009242367A | 2009-10-22 | |||
| JP2009528267A | 2009-08-06 | |||
| JP2009051863A | 2009-03-12 |
Other References:
THANH HOA LE ET AL.: "Adjuvant effects of sophy P-glucan on H5N1 and H5N2 vaccination using a mouse model", TROPICAL MEDICINE AND HEALTH, vol. 38, no. 1, 6 February 2010 (2010-02-06), pages 23 - 27
LE, THANH HOA. ET AL.: "The adjuvant effect of Sophy P-glucan to the antibody response in poultry immunized by the avian influenza A H5N1 and H5N2 vaccines", JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, vol. 21, no. 4, 16 January 2011 (2011-01-16), pages 405 - 411, XP002712241
LE, THANH HOA. ET AL.: "The adjuvant effect of Sophy P-glucan to the antibody response in poultry immunized by the avian influenza A H5N1 and H5N2 vaccines", JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, vol. 21, no. 4, 16 January 2011 (2011-01-16), pages 405 - 411, XP002712241
Attorney, Agent or Firm:
MATSUI SHIGERU (JP)
Shigeru Matsui (JP)
Shigeru Matsui (JP)
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Claims:
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