Title:
IMMUNITY INDUCING AGENT
Document Type and Number:
WIPO Patent Application WO/2017/170338
Kind Code:
A1
Abstract:
The present invention relates to a novel immunity inducing agent for treating and/or preventing cancer. More specifically, the present invention relates to: an immunity inducing agent that comprises as an active ingredient at least one polypeptide, said polypeptide being selected from among MRAP2-derived polypeptides and variants thereof and having an immunity induction activity, or a recombinant vector, said recombinant vector containing a polynucleotide encoding the polypeptide and being capable of expressing the polypeptide in a living organism; and an immunity induction method that comprises administering the immunity inducing agent to a subject.
Inventors:
FUJITA TAKAYUKI (JP)
OKANO FUMIYOSHI (JP)
OKANO FUMIYOSHI (JP)
Application Number:
PCT/JP2017/012269
Publication Date:
October 05, 2017
Filing Date:
March 27, 2017
Export Citation:
Assignee:
TORAY INDUSTRIES (JP)
International Classes:
A61K39/00; A61K35/76; A61K39/39; A61K48/00; A61P35/00; A61P35/02; A61P37/04; C07K14/54; C07K14/555; C07K14/705; C12N15/09
Domestic Patent References:
| WO2015006437A1 | 2015-01-15 |
Other References:
CHAN, L.F. ET AL.: "MRAP and MRAP2 are bidirectional regulators of the melanocortin receptor family", PROC. NATL. ACAD. SCI.USA, vol. 106, no. 15, 14 April 2009 (2009-04-14), pages 6146 - 6151, XP055306434, ISSN: 1091-6490, Retrieved from the Internet
GORRIGAN, R.J. ET AL.: "Localisation of the melanocortin-2-receptor and its accessory proteins in the developing and adult adrenal gland", J. MOL. ENDOCRINOL., vol. 46, no. 3, 1 June 2011 (2011-06-01), pages 227 - 232, XP055306435, ISSN: 0952-5041, Retrieved from the Internet
HOFLAND, J. ET AL.: "Melanocortin 2 Receptor- Associated Protein (MRAP) and MRAP2 in Human Adrenocortical Tissues: Regulation of Expression and Association with ACTH Responsiveness", J. CLIN. ENDOCRINOL. METAB., vol. 97, no. 5, 1 May 2012 (2012-05-01), pages E747 - E754, XP055578863, ISSN: 0021-972X, DOI: 10.1210/jc.2011-2328
See also references of EP 3437652A4
GORRIGAN, R.J. ET AL.: "Localisation of the melanocortin-2-receptor and its accessory proteins in the developing and adult adrenal gland", J. MOL. ENDOCRINOL., vol. 46, no. 3, 1 June 2011 (2011-06-01), pages 227 - 232, XP055306435, ISSN: 0952-5041, Retrieved from the Internet
HOFLAND, J. ET AL.: "Melanocortin 2 Receptor- Associated Protein (MRAP) and MRAP2 in Human Adrenocortical Tissues: Regulation of Expression and Association with ACTH Responsiveness", J. CLIN. ENDOCRINOL. METAB., vol. 97, no. 5, 1 May 2012 (2012-05-01), pages E747 - E754, XP055578863, ISSN: 0021-972X, DOI: 10.1210/jc.2011-2328
See also references of EP 3437652A4
Attorney, Agent or Firm:
HIRAKI Yusuke et al. (JP)
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