Title:
AN IMMUNOGENIC COMPOSITION FOR USE IN A VACCINE AND AN IMMUNODIAGNOSTIC TEST KIT FOR VISCERAL LEISHMANIASIS
Document Type and Number:
WIPO Patent Application WO/2012/019268
Kind Code:
A3
Abstract:
The present invention describes an immunogenic composition for use in a vaccine and a test for immunodiagnosis of visceral leishmaniasis. More specifically, the invention comprises a vaccine and an immunodiagnostic test kit for leishmaniasis, developed through the identification, production and selection of new antigens by means of proteomic analysis, bioinformatics, peptide synthesis and immunoassay. The high specificity of these antigens makes it possible for an effective vaccine to be developed against leishmaniasis, as well as a more efficient test for the immunodiagnosis of canine or human visceral leishmaniasis.
Inventors:
TOSTES GAZZINELLI RICARDO (BR)
MONTEIRO DE ANDRADE HELIDA (BR)
MARIA SILVA COSTA FRANCO MIRIAM (BR)
ROSA FARIA ANGELICA (BR)
MONTEIRO DE ANDRADE HELIDA (BR)
MARIA SILVA COSTA FRANCO MIRIAM (BR)
ROSA FARIA ANGELICA (BR)
Application Number:
PCT/BR2011/000294
Publication Date:
July 26, 2012
Filing Date:
August 12, 2011
Export Citation:
Assignee:
UNIV MINAS GERAIS (BR)
TOSTES GAZZINELLI RICARDO (BR)
MONTEIRO DE ANDRADE HELIDA (BR)
MARIA SILVA COSTA FRANCO MIRIAM (BR)
ROSA FARIA ANGELICA (BR)
TOSTES GAZZINELLI RICARDO (BR)
MONTEIRO DE ANDRADE HELIDA (BR)
MARIA SILVA COSTA FRANCO MIRIAM (BR)
ROSA FARIA ANGELICA (BR)
International Classes:
A61K39/008
Domestic Patent References:
| WO2006108720A2 | 2006-10-19 |
Foreign References:
| US5965142A | 1999-10-12 |
Other References:
PEACOCK, CS ET AL.: "Comparative analysis of genomic threre Leishmaria species causing diverse human disease.", NAT GENET., vol. 39, no. 7, 2007, pages 839 - 847
Attorney, Agent or Firm:
DE LUCA GUIMARÃES, Raissa (Avenida Antônio Carlos 6627,Unidade Administrativa II, 2° andar, sala 200, CEP: -901 Belo Horizonte Minas Gerais, BR)
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