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Title:
IMMUNOSUPPRESSANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/254005
Kind Code:
A1
Abstract:
An immunosuppressant having the structure of formula (I), and a preparation method therefor and the use thereof. The series of compounds of the present invention can be widely used in the preparation of drugs for preventing and/or treating cancers or tumors, immune-related diseases and disorders, communicable diseases, infectious diseases or metabolic diseases mediated by PD-1/PD-L1 signal pathways, which drugs are expected to be developed into a new generation of PD-1/PD-L1 inhibitors.

Inventors:
ZHANG MINGMING (CN)
ZHAO BAOWEI (CN)
YANG FEI (CN)
ZHANG YONGXIAN (CN)
YU HONGPING (CN)
CHEN ZHUI (CN)
XU YAOCHANG (CN)
Application Number:
PCT/CN2021/091383
Publication Date:
December 23, 2021
Filing Date:
April 30, 2021
Export Citation:
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Assignee:
ABBISKO THERAPEUTICS CO LTD (CN)
International Classes:
C07D471/02; A61K31/33; A61K31/395; A61P31/00; A61P35/00; A61P37/00; C07D519/00
Domestic Patent References:
WO2021067217A12021-04-08
WO2019192506A12019-10-10
WO2019217821A12019-11-14
Foreign References:
CN111039942A2020-04-21
Other References:
HETEROCYCL. COMMUN., vol. 6, 2000, pages 25
Attorney, Agent or Firm:
XU & PARTNERS, LLC. (CN)
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