Title:
IMMUNOSUPPRESSANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/254005
Kind Code:
A1
Abstract:
An immunosuppressant having the structure of formula (I), and a preparation method therefor and the use thereof. The series of compounds of the present invention can be widely used in the preparation of drugs for preventing and/or treating cancers or tumors, immune-related diseases and disorders, communicable diseases, infectious diseases or metabolic diseases mediated by PD-1/PD-L1 signal pathways, which drugs are expected to be developed into a new generation of PD-1/PD-L1 inhibitors.
Inventors:
ZHANG MINGMING (CN)
ZHAO BAOWEI (CN)
YANG FEI (CN)
ZHANG YONGXIAN (CN)
YU HONGPING (CN)
CHEN ZHUI (CN)
XU YAOCHANG (CN)
ZHAO BAOWEI (CN)
YANG FEI (CN)
ZHANG YONGXIAN (CN)
YU HONGPING (CN)
CHEN ZHUI (CN)
XU YAOCHANG (CN)
Application Number:
PCT/CN2021/091383
Publication Date:
December 23, 2021
Filing Date:
April 30, 2021
Export Citation:
Assignee:
ABBISKO THERAPEUTICS CO LTD (CN)
International Classes:
A61K31/33; C07D471/02; A61K31/395; A61P31/00; A61P35/00; A61P37/00; C07D519/00
Domestic Patent References:
| WO2021067217A1 | 2021-04-08 | |||
| WO2019192506A1 | 2019-10-10 | |||
| WO2019217821A1 | 2019-11-14 |
Foreign References:
| CN111039942A | 2020-04-21 |
Other References:
HETEROCYCL. COMMUN., vol. 6, 2000, pages 25
See also references of EP 4174066A4
See also references of EP 4174066A4
Attorney, Agent or Firm:
XU & PARTNERS, LLC. (CN)
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