Title:
IMMUNOSUPPRESSIVE AGENT, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/011209
Kind Code:
A1
Abstract:
An immunosuppressive agent having the structure of formula (I), a preparation method therefor, and pharmaceutical use thereof. A series of the compounds have strong inhibitory activity on PD-1/PD-L1 interaction, can be widely used for preparing medicaments for preventing and/or treating cancers or tumors, immune-related diseases and disorders, communicable diseases, infectious diseases or metabolic diseases mediated by PD-1/PD-L1 signaling pathway, and is expected to be developed into a new generation of PD-1/PD-L1 inhibitors.
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Inventors:
ZHANG MINGMING (CN)
ZHANG YONGXIAN (CN)
YU HONGPING (CN)
CHEN ZHUI (CN)
XU YAOCHANG (CN)
ZHANG YONGXIAN (CN)
YU HONGPING (CN)
CHEN ZHUI (CN)
XU YAOCHANG (CN)
Application Number:
PCT/CN2019/095461
Publication Date:
January 16, 2020
Filing Date:
July 10, 2019
Export Citation:
Assignee:
ABBISKO THERAPEUTICS CO LTD (CN)
International Classes:
C07C211/27; A61K31/4025; A61P31/00; A61P35/00; A61P37/00; C07C15/40; C07C15/46; C07C211/29; C07D405/10
Domestic Patent References:
| WO1998050030A1 | 1998-11-12 |
Foreign References:
| CN107573332A | 2018-01-12 | |||
| US6358960B1 | 2002-03-19 | |||
| CN101896457A | 2010-11-24 |
Attorney, Agent or Firm:
XU & PARTNERS, LLC. (CN)
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