Title:
IMPRINT POLYMER AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2007/023915
Kind Code:
A1
Abstract:
Disclosed is an imprint polymer having a recognition site which is reversibly bound to a target protein. Since the recognition site has at least one of a metal complex and a substrate inhibitor, the imprint polymer can have a high specificity for the target protein. Such an imprint polymer is applicable to protein chips or the like.
Inventors:
TAKEUCHI TOSHIFUMI
HISHIYA TAKAYUKI
HISHIYA TAKAYUKI
Application Number:
PCT/JP2006/316642
Publication Date:
March 01, 2007
Filing Date:
August 24, 2006
Export Citation:
Assignee:
JAPAN SCIENCE & TECH AGENCY (JP)
TAKEUCHI TOSHIFUMI
HISHIYA TAKAYUKI
TAKEUCHI TOSHIFUMI
HISHIYA TAKAYUKI
International Classes:
C07K17/08; B01J20/26; C07C237/06; C07D257/02; C07F1/08; C07K1/22; C08F30/00; C12M1/00; C12M1/34; C12N11/08; C12Q1/00; G01N33/53; G01N33/566
Other References:
KEMPE M. ET AL.: "An Approach Towards Surface Imprinting Using the Enzyme Ribonuclease A", JOURNAL OF THE MOLECULAR RECOGNITION, vol. 8, 1995, pages 35 - 39, XP002050518
TAKEUCHI T.: "Kobunshi Probe to Shiteno Molecular Imprinting Polymer", KOBUNSHI, vol. 52, no. 7, 2003, pages 458 - 461, XP003008639
SEKO A. ET AL.: "Bunshi Ninshiki Bui ni Porphyrin Tessakutai o Motsu Imprinting Polymer (Molecularly Imprinted Polymers having Fe(III)Porphyrin Residues)", CSJ: THE CHEMICAL SOCIETY OF JAPAN KOEN YOKOSHU, vol. 81, no. 2, 2002, pages 834, XP003008640
HISHIYA T. ET AL.: "Kinzoku sakutai o Imprinting Shita Protein Ninshiki Kobunshi no Kaihatsu (Preparation of polymer materials selective for proteins by using molecular imprinting of metal complexes)", CSJ: THE CHEMICAL SOCIETY OF JAPAN KOEN YOKOSHU, vol. 86, no. 2, 2006, pages 899, XP003008641
BUROW M. ET AL.: "Molecular Imprinting: Synthesis of Polymer Particles with Antibody-like Binding Characteristics for Glucose Oxidase", BIOCHEM. BIOPHYS. RES. COMMUN., vol. 227, 1996, pages 419 - 422, XP002082389
VENTON D.L. ET AL.: "Influence of protein on polysiloxane polymer formation: evidence for induction of complementary protein-polymer interactions", BIOCHIMICA ET BIOPHYSICA ACTA, vol. 1250, 1995, pages 126 - 136, XP001187532
TAKEUCHI T.: "Kobunshi Probe to Shiteno Molecular Imprinting Polymer", KOBUNSHI, vol. 52, no. 7, 2003, pages 458 - 461, XP003008639
SEKO A. ET AL.: "Bunshi Ninshiki Bui ni Porphyrin Tessakutai o Motsu Imprinting Polymer (Molecularly Imprinted Polymers having Fe(III)Porphyrin Residues)", CSJ: THE CHEMICAL SOCIETY OF JAPAN KOEN YOKOSHU, vol. 81, no. 2, 2002, pages 834, XP003008640
HISHIYA T. ET AL.: "Kinzoku sakutai o Imprinting Shita Protein Ninshiki Kobunshi no Kaihatsu (Preparation of polymer materials selective for proteins by using molecular imprinting of metal complexes)", CSJ: THE CHEMICAL SOCIETY OF JAPAN KOEN YOKOSHU, vol. 86, no. 2, 2006, pages 899, XP003008641
BUROW M. ET AL.: "Molecular Imprinting: Synthesis of Polymer Particles with Antibody-like Binding Characteristics for Glucose Oxidase", BIOCHEM. BIOPHYS. RES. COMMUN., vol. 227, 1996, pages 419 - 422, XP002082389
VENTON D.L. ET AL.: "Influence of protein on polysiloxane polymer formation: evidence for induction of complementary protein-polymer interactions", BIOCHIMICA ET BIOPHYSICA ACTA, vol. 1250, 1995, pages 126 - 136, XP001187532
Attorney, Agent or Firm:
HARAKENZO WORLD PATENT & TRADEMARK (2-6 Tenjinbashi 2-chome Kita, Kita-k, Osaka-shi Osaka, JP)
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