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Title:
IMPROVED OSTEOINDUCTIVE MATERIALS
Document Type and Number:
WIPO Patent Application WO2004084965
Kind Code:
A3
Abstract:
The present invention relates to an osteoinductive materials comprising a matrix materials with morphogenetic protein (s) absorbed on inner or outer surfaces of this matrix material, wherein the osteoinductive material is obtainable by contacting the matrix material and the morphogenic protein (s) under conditions of pH and ionic concentration to keep protein stable and dissolved in a solution until dried and thereby allowing that the matrix material becomes evenly coated with the morphogenic protein (s).

Inventors:
POHL JENS (DE)
BECHTOLD ROLF (DE)
KRUSE MICHAEL (DE)
Application Number:
PCT/EP2004/003238
Publication Date:
November 25, 2004
Filing Date:
March 26, 2004
Export Citation:
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Assignee:
BIOPH BIOTECH ENTW PHARM GMBH (DE)
POHL JENS (DE)
BECHTOLD ROLF (DE)
KRUSE MICHAEL (DE)
International Classes:
A61L27/34; A61L27/56; C07K14/475; C07K14/495; C07K14/51; (IPC1-7): A61L27/34; A61L27/56; C07K14/475
Domestic Patent References:
WO1994015653A11994-07-21
Foreign References:
US6118043A2000-09-12
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