Title:
IMPROVED PEPTIDE NUCLEIC ACID COMPLEX
Document Type and Number:
WIPO Patent Application WO/2024/101915
Kind Code:
A1
Abstract:
The present invention relates to a peptide nucleic acid complex having enhanced stability and improved inhibitory effects on a target gene, wherein the terminals of a bioactive peptide nucleic acid and a carrier peptide nucleic acid are modified with a protecting group.
Inventors:
KIM HYE JOO (KR)
YU JI-YEON (KR)
JO SUNG GANG (KR)
OK YE-JIN (KR)
PARK HEE KYUNG (KR)
YU JI-YEON (KR)
JO SUNG GANG (KR)
OK YE-JIN (KR)
PARK HEE KYUNG (KR)
Application Number:
PCT/KR2023/017968
Publication Date:
May 16, 2024
Filing Date:
November 09, 2023
Export Citation:
Assignee:
SEASUN THERAPEUTICS (KR)
International Classes:
C12N15/113; A61K31/7088; A61K47/54; A61K48/00; A61P1/16; A61P25/28; A61P27/02; A61P29/00; A61P35/00; A61P37/00
Domestic Patent References:
| WO2016069912A1 | 2016-05-06 |
Foreign References:
| KR20200090419A | 2020-07-29 | |||
| KR20220041397A | 2022-04-01 | |||
| KR20220085311A | 2022-06-22 | |||
| KR20220085312A | 2022-06-22 | |||
| KR20190096148A | 2019-08-19 |
Other References:
MARTIN MOLLY E.; RICE KEVIN G.: "Peptide-guided gene delivery", THE AAPS JOURNAL, SPRINGER-VERLAG, NEW YORK, vol. 9, no. 1, 1 January 1901 (1901-01-01), New York , pages E18 - E29, XP035718877, DOI: 10.1208/aapsj0901003
Attorney, Agent or Firm:
LEE, Cheo Young et al. (KR)
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