Title:
IMPROVING PRODUCTION CHARACTERISTICS OF CATTLE
Document Type and Number:
WIPO Patent Application WO2005007881
Kind Code:
A8
Abstract:
A single nucleotide polymorphism (SNP) in exon 2 of the cattle IGF2 gene is associated in cattle with phenotypes of increased rib eye area, decreased fat content, decreased marbling, and decreased birth weight. The presence of a C residue at position 150 of SEQ ID NO: 1, results in increased rib eye area, decreased fat content, and decreased marbling. Expression of the IGF2 gene is also affected by genomic imprinting, with the maternally derived IGF2 allele being suppressed during gestation. As a result, an offspring that obtains a paternal IGF2 allele with a C residue at position 150 of SEQ ID NO: 1 will display a phenotype of reduced birth weight as compared to offspring with a paternally derived IGF2 allele with a T residue at this position.
Inventors:
SCHMUTZ SHEILA MARIE (CA)
GOODALL JULIE JANINE (CA)
GOODALL JULIE JANINE (CA)
Application Number:
PCT/CA2004/001039
Publication Date:
May 06, 2005
Filing Date:
July 20, 2004
Export Citation:
Assignee:
SCHMUTZ SHEILA MARIE (CA)
GOODALL JULIE JANINE (CA)
GOODALL JULIE JANINE (CA)
International Classes:
C12Q1/68; (IPC1-7): C12Q1/68
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