Title:
IN VIVO SITE-SPECIFIC INCORPORATION OF N-ACETYL-GALACTOSAMINE AMINO ACIDS IN EUBACTERIA
Document Type and Number:
WIPO Patent Application WO2006045116
Kind Code:
A3
Abstract:
Methods and compositions for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid having a N-cetylgalactosamine moiety into a protein; optionally, the N-acetylgalactosamine-containing unnatural amino acid can be further modified with additional sugars.
Inventors:
SCHULTZ PETER G (US)
HANSON SARAH R (US)
XU RAN (US)
ZHANG ZHIWEN (US)
WONG CHI-HUEY (US)
HANSON SARAH R (US)
XU RAN (US)
ZHANG ZHIWEN (US)
WONG CHI-HUEY (US)
Application Number:
PCT/US2005/038250
Publication Date:
December 28, 2006
Filing Date:
October 20, 2005
Export Citation:
Assignee:
SCRIPPS RESEARCH INST (US)
SCHULTZ PETER G (US)
HANSON SARAH R (US)
XU RAN (US)
ZHANG ZHIWEN (US)
WONG CHI-HUEY (US)
SCHULTZ PETER G (US)
HANSON SARAH R (US)
XU RAN (US)
ZHANG ZHIWEN (US)
WONG CHI-HUEY (US)
International Classes:
C12P21/06; C07H21/04; C12N1/21; C12N9/22; C12N15/74; C12P19/34
Domestic Patent References:
| WO2002086075A2 | 2002-10-31 |
Foreign References:
| US6927042B2 | 2005-08-09 |
Other References:
See also references of EP 1809758A4
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