Title:
INDAZOLE FORMAMIDE DERIVATIVES, PREPARATION METHOD THEREFOR, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/046223
Kind Code:
A1
Abstract:
The present application relates to substituted indazole formamide derivatives, a preparation method therefor, and the use of a pharmaceutical composition containing the derivatives or deuterated derivatives in medicines. Specifically, the present application relates to substituted indazole formamide derivatives represented by general formula (I), a preparation method therefor, pharmaceutically acceptable salts thereof, and the use thereof as a CGRP receptor antagonist in prevention and/or treatment of CGRP-related diseases, in particular in the field of migraine. The definition of each substituent in general formula (I) is the same as that in the description.
Inventors:
YING YONGCHENG (CN)
LI GUOCHUN (CN)
YUAN XIAOHUI (CN)
YU SHANGHAI (CN)
GU LIMING (CN)
LOU WANQIAO (CN)
LI GUOCHUN (CN)
YUAN XIAOHUI (CN)
YU SHANGHAI (CN)
GU LIMING (CN)
LOU WANQIAO (CN)
Application Number:
PCT/CN2023/114866
Publication Date:
March 07, 2024
Filing Date:
August 25, 2023
Export Citation:
Assignee:
BRISE PHARMACEUTICALS CO LTD (CN)
International Classes:
C07D265/00; A61K31/496; A61P25/06; A61P29/00; C07D401/14; C07D498/20
Domestic Patent References:
| WO2021176088A1 | 2021-09-10 |
Foreign References:
| CN102834388A | 2012-12-19 | |||
| CN1917921A | 2007-02-21 | |||
| US20050227968A1 | 2005-10-13 | |||
| US20040204397A1 | 2004-10-14 | |||
| CN1671711A | 2005-09-21 | |||
| US20070149503A1 | 2007-06-28 | |||
| CN108431005A | 2018-08-21 | |||
| CN108430991A | 2018-08-21 |
Attorney, Agent or Firm:
BEIJING TANGSONG IP FIRM (CN)
Download PDF: