Title:
INDOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL USE THEREOF
Document Type and Number:
WIPO Patent Application WO/1994/007896
Kind Code:
A1
Abstract:
An indole derivative represented by general formula (I) and a pharmacologically acceptable acid addition salt thereof, wherein R1 represents alkyl, cycloalkyl, etc.; R2 represents hydrogen, hydroxy, alkanoyloxy or alkoxy; R3 represents hydrogen, alkyl, alkanoyl or benzyl; R4 represents hydrogen, alkyl or benzyl; and R5 and R6 represent each independently hydrogen, iodine, trifluoromethyl, trifluoromethoxy, etc. The invention also provides an immunosuppressant, antiallergic, antiinflammatory and brain cell protectant each containing the above derivative or salt as the active ingredient.
Inventors:
NAGASE HIROSHI (JP)
MIZUSUNA AKIRA (JP)
KAWAI KOJI (JP)
NAKATANI IZUMI (JP)
MIZUSUNA AKIRA (JP)
KAWAI KOJI (JP)
NAKATANI IZUMI (JP)
Application Number:
PCT/JP1993/001388
Publication Date:
April 14, 1994
Filing Date:
September 29, 1993
Export Citation:
Assignee:
TORAY INDUSTRIES (JP)
NAGASE HIROSHI (JP)
MIZUSUNA AKIRA (JP)
KAWAI KOJI (JP)
NAKATANI IZUMI (JP)
NAGASE HIROSHI (JP)
MIZUSUNA AKIRA (JP)
KAWAI KOJI (JP)
NAKATANI IZUMI (JP)
International Classes:
A61K31/44; A61K31/485; C07D489/10; C07D491/20; C07D491/22; (IPC1-7): C07D489/10; A61K31/485
Foreign References:
| JPH03223288A | 1991-10-02 |
Other References:
See also references of EP 0614898A4
Download PDF: