Title:
INDOTRICARBOCYANINE DYE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/151981
Kind Code:
A1
Abstract:
The present invention belongs to the field of medicines, and in particular relates to an indotricarbocyanine dye compound, a preparation method therefor and the use thereof. A large-conjugate water-soluble indotricarbocyanine dye compound is synthesized and prepared in the present invention, and the compound can be used as a fluorescent dye and has potential development and application prospects. In the present invention, a related analysis method of the compound is also developed, which can provide a research basis for the research into impurities in indocyanine green medicaments and can provide a basis for the safety research into the indocyanine green medicaments.
Inventors:
CAI HUIMING (CN)
LU ZHENZHEN (CN)
ZHU XIONG (CN)
DING YE (CN)
LU ZHENZHEN (CN)
ZHU XIONG (CN)
DING YE (CN)
Application Number:
PCT/CN2021/142774
Publication Date:
July 21, 2022
Filing Date:
December 30, 2021
Export Citation:
Assignee:
NANJING NUOYUAN MEDICAL DEVICES CO LTD (CN)
International Classes:
C07D209/08; C09B23/12; G01N30/02; G01N30/04
Foreign References:
| CN112876398A | 2021-06-01 | |||
| CN103073909A | 2013-05-01 | |||
| CN110387137A | 2019-10-29 | |||
| US2895955A | 1959-07-21 |
Other References:
RÜTTGER FRANZISKA, MINDT SONANI, GOLZ CHRISTOPHER, ALCARAZO MANUEL, JOHN MICHAEL: "Isomerization and Dimerization of Indocyanine Green and a Related Heptamethine Dye", EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, vol. 2019, no. 30, 15 August 2019 (2019-08-15), DE , pages 4791 - 4796, XP055931626, ISSN: 1434-193X, DOI: 10.1002/ejoc.201900715
Attorney, Agent or Firm:
JW IP LAW FIRM (CN)
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