Title:
INDUCED PLURIPOTENT STEM CELLS OF ALZHEIMER'S DISEASE PATIENT WITH MUTATION (V715M) IN AMYLOID PRECURSOR PROTEIN
Document Type and Number:
WIPO Patent Application WO/2020/231089
Kind Code:
A1
Abstract:
The present invention relates to: screening for Alzheimer's-related diseases by using induced pluripotent stem cells with a mutation in an amyloid precursor protein (val715met) derived from blood cells; a personalized therapeutic agent; and a preparation method therefor.
More Like This:
Inventors:
SONG JI HWAN (KR)
LI LING (KR)
LI LING (KR)
Application Number:
PCT/KR2020/006056
Publication Date:
November 19, 2020
Filing Date:
May 07, 2020
Export Citation:
Assignee:
IPS BIO INC (KR)
International Classes:
C12N5/074; C12N5/0793; G01N33/50
Foreign References:
| KR20140125682A | 2014-10-29 | |||
| KR20130133598A | 2013-12-09 | |||
| KR20180033062A | 2018-04-02 |
Other References:
SONG, JIHWAN; LI, LING; KIM, HEE JIN; CHANG, JONG WOOK; AND NA, DUK L: "W-1152 Generation and phenotype characterization of ad patient-specific IPSC lines", ISSCR 2017 ANNUAL MEETING, INTERNATIONAL SOCIETY FOR STEM CELL RESEARCH, 14-17 JUNE, BOSTON , 2017, pages 132, XP009524683, DOI: W-1152
MUNENARI ITOH, KAWAGOE SHIHO, OKANO HIROTAKA JAMES, NAKAGAWA HIDEMI: "Integration-free T cell -derived human induced pluripotent stem cells (iPSCs) from a patient with lymphedema-distichiasis syndrome (LDS) carrying an insertion-deletion complex mutation in the FOXC2 gene", STEM CELL RESEARCH, vol. 16, no. 3, 1 May 2016 (2016-05-01), pages 611 - 613, XP055760965, ISSN: 1873-5061, DOI: 10.1016/j.scr.2016.03.004
MUNENARI ITOH, KAWAGOE SHIHO, OKANO HIROTAKA JAMES, NAKAGAWA HIDEMI: "Integration-free T cell -derived human induced pluripotent stem cells (iPSCs) from a patient with lymphedema-distichiasis syndrome (LDS) carrying an insertion-deletion complex mutation in the FOXC2 gene", STEM CELL RESEARCH, vol. 16, no. 3, 1 May 2016 (2016-05-01), pages 611 - 613, XP055760965, ISSN: 1873-5061, DOI: 10.1016/j.scr.2016.03.004
Attorney, Agent or Firm:
Y.P.LEE, MOCK & PARTNERS (KR)
Download PDF: