INDUCER FOR EXPRESSION OF DESMOPLAKIN OR INDUCER FOR LOCALIZATION OF DESMOPLAKIN IN CELL MEMBRANE, WHICH CONTAINS PHENYLETHYLAMINE DERIVATIVE OR SYNEPHRINE

Title:

INDUCER FOR EXPRESSION OF DESMOPLAKIN OR INDUCER FOR LOCALIZATION OF DESMOPLAKIN IN CELL MEMBRANE, WHICH CONTAINS PHENYLETHYLAMINE DERIVATIVE OR SYNEPHRINE

Document Type and Number:

WIPO Patent Application WO/2015/194054

Kind Code:

A1

Abstract:

It becomes possible to provide: a novel and useful inducer for the expression of desmoplakin or inducer for the localization of desmoplakin in cell membrane; and a cosmetic composition which relies on an activity of inducing the expression of desmoplakin or an activity of inducing the localization of desmoplakin in a cell membrane. Provided are: an inducer for the expression of desmoplakin or an inducer for the localization of desmoplakin in cell membrane, which comprises a phenylethylamine derivative or synephrine; and a cosmetic composition which relies on an activity of inducing the expression of desmoplakin or an activity of inducing the localization of desmoplakin in a cell membrane induced by a phenylethylamine derivative or synephrine.

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Inventors:

MASUTANI TERUAKI (JP)
ITO KENNICHI (JP)

Application Number:

PCT/JP2014/069634

Publication Date:

December 23, 2015

Filing Date:

July 25, 2014

Export Citation:

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Assignee:

ICHIMARU PHARCOS INC (JP)

International Classes:

A61K8/41; A61K31/35; A61P17/00; A61P43/00; A61Q5/02; A61Q5/12; A61Q7/00; A61Q11/00; A61Q17/04; A61Q19/00; A61Q19/10

Domestic Patent References:

WO2013122994A1	2013-08-22
WO2013080205A1	2013-06-06

Foreign References:

JP2001019607A	2001-01-23
JP2003524649A	2003-08-19
JP2004506677A	2004-03-04
JP2007106697A	2007-04-26
JP2001288113A	2001-10-16
JP2013180970A	2013-09-12

Other References:

TERUAKI MASUTANI ET AL.: "Phenylethylamine Yudotai Gan'yu Mandarin Orange Kahi Chushutsubutsu no Hito Hyohi Kozo Kyoka Kino to sono Mechanism Kaiseki", ABSTRACTS OF THE 134TH ANNUAL MEETING OF PHARMACEUTICAL SOCIETY OF JAPAN 2, 280-PM14S, THE 134TH ANNUAL MEETING OF PHARMACEUTICAL SOCIETY OF JAPAN SOSHIKI IINKAI, 5 March 2014 (2014-03-05), pages 88
TERUAKI MASUTANI ET AL., PROCEEDINGS OF THE 133RD ANNUAL MEETING OF THE PHARMACEUTICAL SOCIETY OF JAPAN (YOKOHAMA, 30 March 2013 (2013-03-30), Retrieved from the Internet [retrieved on 20140611]
MICHIO SHIBATA ET AL.: "Research of sensitive skin and skin barrier for development of non- irritating skincare products", FRAGRANCE JOURNAL, August 2012 (2012-08-01), pages 16 - 20

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