Title:
INHIBITOR OF INTERACTION BETWEEN YAP/TAZ AND TEAD, PREPARATION THEREOF, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/155927
Kind Code:
A1
Abstract:
The present disclosure provides an inhibitor, represented by formula I, of interaction between YAP/TAZ and TEAD, preparation thereof, a pharmaceutical composition thereof and use thereof. The compound provided in the present disclosure can be used as an inhibitor of interaction between YAP/TAZ and TEAD, and is used for treating or preventing diseases mediated by interaction between YAP/TAZ and TEAD.
Inventors:
ZHENG QIANGANG (CN)
JIANG XIANGQING (CN)
LU JITING (CN)
ZHUGE HAO (CN)
YAO JIAQI (CN)
YANG KUN (CN)
LIU JING (CN)
XU MING (CN)
LI JING (CN)
ZENG QINGLONG (CN)
ZHONG XIAOFENG (CN)
ZHU JIDONG (CN)
JIANG XIANGQING (CN)
LU JITING (CN)
ZHUGE HAO (CN)
YAO JIAQI (CN)
YANG KUN (CN)
LIU JING (CN)
XU MING (CN)
LI JING (CN)
ZENG QINGLONG (CN)
ZHONG XIAOFENG (CN)
ZHU JIDONG (CN)
Application Number:
PCT/CN2023/077504
Publication Date:
August 24, 2023
Filing Date:
February 21, 2023
Export Citation:
Assignee:
ETERN BIOPHARMA SHANGHAI CO LTD (CN)
International Classes:
C07D405/14; A61K31/343; A61K31/443; A61P35/00; C07D307/81; C07D401/14; C07D403/14; C07D407/14; C07D413/14; C07D417/14; C07D491/14
Domestic Patent References:
| WO2021186324A1 | 2021-09-23 | |||
| WO2020047035A1 | 2020-03-05 | |||
| WO2017053706A1 | 2017-03-30 |
Foreign References:
| CN112805267A | 2021-05-14 | |||
| US20090118267A1 | 2009-05-07 | |||
| CN109776377A | 2019-05-21 |
Attorney, Agent or Firm:
AFD CHINA INTELLECTUAL PROPERTY LAW OFFICE (CN)
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