Title:
INHIBITOR OF PLASMINOGEN ACTIVATOR INHIBITOR-1
Document Type and Number:
WIPO Patent Application WO/2009/013915
Kind Code:
A8
Abstract:
An inhibitor of plasminogen activator inhibitor-1 (PAI-1). A medicinal composition having an effect of inhibiting the PAI-1 activity and being efficacious in preventing or treating various diseases for the onset of which the PAI-1 activity is responsible. A novel compound represented by the following general formula (I) which has an activity of inhibiting PAI-1 and a salt thereof: [Chemical formula 1] wherein each symbol is as defined in the description.
Inventors:
MIYATA TOSHIO (JP)
YAMAOKA NAGAHISA (JP)
KODAMA HIDEHIKO (JP)
YAMAOKA NAGAHISA (JP)
KODAMA HIDEHIKO (JP)
Application Number:
PCT/JP2008/054543
Publication Date:
April 23, 2009
Filing Date:
March 12, 2008
Export Citation:
Assignee:
RENASCIENCE CO LTD (JP)
MIYATA TOSHIO (JP)
YAMAOKA NAGAHISA (JP)
KODAMA HIDEHIKO (JP)
MIYATA TOSHIO (JP)
YAMAOKA NAGAHISA (JP)
KODAMA HIDEHIKO (JP)
International Classes:
C07C233/54; A61K31/196; A61K31/27; A61K31/381; A61K31/4035; A61K31/4535; A61K31/495; A61K31/496; A61K31/5377; A61P7/00; A61P7/02; A61P13/12; A61P27/02; A61P43/00; C07C235/16; C07C237/04; C07C271/22; C07C275/30; C07C311/19; C07D295/18; C07D333/36; C07D409/12
Attorney, Agent or Firm:
SAEGUSA, Eiji et al. (1-7-1 Doshomachi,Chuo-ku, Osaka-sh, Osaka 45, JP)
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