Title:
CBP/EP300 INHIBITOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/213521
Kind Code:
A1
Abstract:
Provided are a compound represented by formula (I), a stereoisomer thereof or a pharmaceutically acceptable salt thereof, and a use thereof in preparing a drug for diseases mediated by CBP and/or EP300.
Inventors:
WANG LISHA (CN)
ZHANG ENGE (CN)
LI JIN (CN)
ZHANG ENGE (CN)
LI JIN (CN)
Application Number:
PCT/CN2021/089486
Publication Date:
October 28, 2021
Filing Date:
April 25, 2021
Export Citation:
Assignee:
PHARMABLOCK SCIENCES NANJING INC (CN)
International Classes:
C07D401/14; A61K31/475; A61P9/00; A61P29/00; A61P31/12; A61P35/00; A61P37/00; C07D405/14; C07D409/14; C07D413/04; C07D413/14; C07D471/04; C07D487/04
Domestic Patent References:
| WO2019204781A1 | 2019-10-24 |
Foreign References:
| CN109476641A | 2019-03-15 | |||
| CN107108512A | 2017-08-29 | |||
| JP2012072068A | 2012-04-12 |
Other References:
SARAH M. BRONNER, JEREMY MURRAY, F. ANTHONY ROMERO, KWONG WAH LAI, VICKIE TSUI, PATRICK CYR, MAUREEN H. BERESINI, GLADYS DE LEON B: "A Unique Approach to Design Potent and Selective Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP) Inhibitors", JOURNAL OF MEDICINAL CHEMISTRY, vol. 60, no. 24, 28 December 2017 (2017-12-28), US , pages 10151 - 10171, XP055450236, ISSN: 0022-2623, DOI: 10.1021/acs.jmedchem.7b01372
See also references of EP 4140996A4
See also references of EP 4140996A4
Attorney, Agent or Firm:
BEYOND ATTORNEYS AT LAW (CN)
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