Title:
INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHODS OF THEIR USE
Document Type and Number:
WIPO Patent Application WO/2018/103058
Kind Code:
A1
Abstract:
Compounds of formula (I') and methods of their use and preparation, as well as compositions comprising compounds of formula (I').
Inventors:
CAI MIN (CN)
ARORA NIDHI (US)
BACANI GENESIS M (US)
BARBAY JOSEPH KENT (US)
BEMBENEK SCOTT D (US)
CHEN WEI (CN)
DECKHUT CHARLOTTE POOLEY (US)
EDWARDS JAMES P (US)
GHOSH BRAHMANANDA (US)
HAO BAOYU (CN)
KREUTTER KEVIN D (US)
LI GANG (CN)
TICHENOR MARK S (US)
VENABLE JENNIFER D (US)
WEI JIANMEI (US)
WIENER JOHN J M (US)
WU YAO (CN)
ZHU YAOPING (CN)
ZHANG FEIHUANG (CN)
ZHANG ZHENG (CN)
XIAO KUN (CN)
ARORA NIDHI (US)
BACANI GENESIS M (US)
BARBAY JOSEPH KENT (US)
BEMBENEK SCOTT D (US)
CHEN WEI (CN)
DECKHUT CHARLOTTE POOLEY (US)
EDWARDS JAMES P (US)
GHOSH BRAHMANANDA (US)
HAO BAOYU (CN)
KREUTTER KEVIN D (US)
LI GANG (CN)
TICHENOR MARK S (US)
VENABLE JENNIFER D (US)
WEI JIANMEI (US)
WIENER JOHN J M (US)
WU YAO (CN)
ZHU YAOPING (CN)
ZHANG FEIHUANG (CN)
ZHANG ZHENG (CN)
XIAO KUN (CN)
Application Number:
PCT/CN2016/109134
Publication Date:
June 14, 2018
Filing Date:
December 09, 2016
Export Citation:
Assignee:
JANSSEN PHARMACEUTICA NV (BE)
CAI MIN (CN)
CAI MIN (CN)
International Classes:
C07D221/00; A61K31/438; A61K31/495; A61K31/498; A61P29/00; A61P35/00; C07D221/08; C07D487/02; C07D513/16
Domestic Patent References:
| WO2007092879A2 | 2007-08-16 |
Foreign References:
| CN105026400A | 2015-11-04 | |||
| CN101056639A | 2007-10-17 |
Other References:
THOMAS P. SELBY: "Synthesis of a Novel Thiadiazacyclazine", JOURNAL OF ORGANIC CHEMISTRY, vol. 53, no. 10, 31 December 1988 (1988-12-31), pages 2386 - 2388, XP055509093
Attorney, Agent or Firm:
CHINA PATENT AGENT (H.K.) LTD. (CN)
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