Title:
INHIBITORS OF CATHEPSIN S
Document Type and Number:
WIPO Patent Application WO2004084842
Kind Code:
A3
Abstract:
The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme (e.g., cathespin K). The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.
Inventors:
LIU HONG (US)
TULLY DAVID (US)
EPPLE ROBERT (US)
BURSULAYA BADRY (US)
WILLIAMS JENNIFER (US)
CHATTERJEE ARNAB (US)
HARRIS JENNIFER LESLIE (US)
LI JUN (US)
TULLY DAVID (US)
EPPLE ROBERT (US)
BURSULAYA BADRY (US)
WILLIAMS JENNIFER (US)
CHATTERJEE ARNAB (US)
HARRIS JENNIFER LESLIE (US)
LI JUN (US)
Application Number:
PCT/US2004/009218
Publication Date:
November 25, 2004
Filing Date:
March 24, 2004
Export Citation:
Assignee:
IRM LLC (US)
LIU HONG (US)
TULLY DAVID (US)
EPPLE ROBERT (US)
BURSULAYA BADRY (US)
WILLIAMS JENNIFER (US)
CHATTERJEE ARNAB (US)
HARRIS JENNIFER LESLIE (US)
LI JUN (US)
LIU HONG (US)
TULLY DAVID (US)
EPPLE ROBERT (US)
BURSULAYA BADRY (US)
WILLIAMS JENNIFER (US)
CHATTERJEE ARNAB (US)
HARRIS JENNIFER LESLIE (US)
LI JUN (US)
International Classes:
C07C237/14; C07C237/20; C07C255/57; C07C275/28; C07C275/30; C07C275/42; C07D213/56; C07D213/64; C07D231/12; C07D237/24; C07D239/52; C07D277/30; C07D277/56; C07D307/38; C07D307/40; C07D307/68; C07D333/20; C07D333/38; A61K; (IPC1-7): A16K31/34; C07D307/38; C07D307/40
Domestic Patent References:
| WO2000048993A1 | 2000-08-24 |
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