INHIBITORS OF INFLAMMATION AND REPERFUSION INJURY

Title:

INHIBITORS OF INFLAMMATION AND REPERFUSION INJURY

Document Type and Number:

WIPO Patent Application WO2001077075

Kind Code:

A3

Abstract:

The invention provides a novel class of substituted isoindolinone derivatives. Pharmaceutical compositions, and methods of making and using the compounds, or pharmaceutically acceptable salts, hydrates, prodrugs, or mixtures thereof are also described.

Inventors:

JAPTAP PRAKASH (US)
SOUTHAN GARRY (US)
SALZMAN ANDREW (US)
SZABO CSABA (US)
RAM SIYA (US)

Application Number:

PCT/US2001/011288

Publication Date:

March 28, 2002

Filing Date:

April 06, 2001

Export Citation:

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Assignee:

INOTEK CORP (US)
JAPTAP PRAKASH (US)
SOUTHAN GARRY (US)
SALZMAN ANDREW (US)
SZABO CSABA (US)
RAM SIYA (US)

International Classes:

A61P19/02; C07D209/46; C07D401/12; C07D403/12; C07D473/34; C07D473/40; C07H19/04; (IPC1-7): C07D209/34; A61K31/404; A61P43/00; C07D401/12; C07D403/12; C07D405/12; C07D409/12; C07D473/34; C07D473/40; C07H19/04; C07H19/067; C07H19/167

Domestic Patent References:

WO1999036402A1	1999-07-22
WO1999041276A1	1999-08-19
WO1999011624A1	1999-03-11

Foreign References:

US3857947A	1974-12-31
GB1380765A	1975-01-15
EP0679396A1	1995-11-02

Other References:

CHEMICAL ABSTRACTS, vol. 72, no. 25, 22 June 1970, Columbus, Ohio, US; abstract no. 132428s, BABICHEV, F. S. ET AL.: "Reactions of o-(chloromethyl)benzonitrile with amines. Condensation of 0-(chloromethyl)benzonitrile with aromatic and aliphatic amines." XP002183492

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