Title:
INJECTABLE COMPOSITION CONTAINING CASPASE INHIBITOR, AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2022/114876
Kind Code:
A1
Abstract:
The present invention relates to an injectable pharmaceutical composition containing a caspase inhibitor, and a preparation method therefor, and, more specifically, to an injectable pharmaceutical composition, and a preparation method therefor, the composition comprising: as an active ingredient, (R)-N-((2S,3S)-2-(fluoromethyl)-2-hydroxy-5-oxotetrahydrofuran-3-yl)-5-isopropyl-3-(isoquinolin-1-yl)-4,5-dihydroisoxazole-5-carboxamide, which is a caspase inhibitor, or a pharmaceutically acceptable salt or isomer thereof; and, as a biocompatible polymer, microspheres containing poly(lactide-co-glycolide).
Inventors:
YOO SEOK CHEOL (KR)
KIM SUNG WON (KR)
PARK JUNG GYU (KR)
CHOI SEI HYUN (KR)
PARK HEE DONG (KR)
BAEK JAE UK (KR)
KIM SUNG WON (KR)
PARK JUNG GYU (KR)
CHOI SEI HYUN (KR)
PARK HEE DONG (KR)
BAEK JAE UK (KR)
Application Number:
PCT/KR2021/017717
Publication Date:
June 02, 2022
Filing Date:
November 29, 2021
Export Citation:
Assignee:
LG CHEMICAL LTD (KR)
International Classes:
A61K9/16; A61K9/00; A61K31/4725; A61P19/02; A61P29/00
Domestic Patent References:
| WO2019092637A1 | 2019-05-16 | |||
| WO2006090997A1 | 2006-08-31 |
Foreign References:
| KR20200126928A | 2020-11-09 | |||
| KR20020005215A | 2002-01-17 | |||
| KR20100054750A | 2010-05-25 | |||
| KR20100042768A | 2010-04-27 |
Other References:
See also references of EP 4248950A4
Attorney, Agent or Firm:
HANSUNG INTELLECTUAL PROPERTY (KR)
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