Title:
INJECTION COMPOSITION CONTAINING ISOLATED MITOCHONDRIA, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/055134
Kind Code:
A1
Abstract:
The present invention relates to an injection composition containing isolated mitochondria. More specifically, the present invention relates to a liquid injection composition containing glycine, sugars, a buffer and mitochondria, and a pharmaceutical composition containing the liquid injection composition as an active ingredient. The liquid injection composition according to the present invention strengthens the stability of mitochondria for prevention or treatment of mitochondria-related diseases and prevents and inhibits thrombogenesis in the blood of a subject to whom the composition is administered, and thus can ensure the safety of a mitochondrial therapeutic agent and maintain the activity of mitochondria. Therefore, a composition according to the present invention resolves aggregation, which can occur during the administration of mitochondria into the body, and thus, in order to prevent and treat various diseases caused by mitochondria dysfunction, mitochondria can be safely and effectively injected into the body.
More Like This:
| WO/2005/053736 | ORAL VACCINE, METHOD FOR ITS PREPARATION AND USE THEREOF |
| WO/2004/095921 | SPORICIDAL COMPOSITION |
| WO/1996/032958 | METHOD FOR TREATMENT OF PAIN |
Inventors:
KANG YOUNG-CHEOL (KR)
HAN KYUBOEM (KR)
LIM SANG-MIN (KR)
JUNG HAHNSUN (KR)
HWANG HYE JEONG (KR)
SON JUNYOUNG (KR)
HAN KYUBOEM (KR)
LIM SANG-MIN (KR)
JUNG HAHNSUN (KR)
HWANG HYE JEONG (KR)
SON JUNYOUNG (KR)
Application Number:
PCT/KR2021/010592
Publication Date:
March 17, 2022
Filing Date:
August 10, 2021
Export Citation:
Assignee:
PAEAN BIOTECHNOLOGY INC (KR)
International Classes:
A61K9/08; A61K9/00; A61K35/12; A61K47/18; A61K47/26; A61P9/10; A61P25/00; A61P29/00
Domestic Patent References:
| WO2012102645A2 | 2012-08-02 |
Foreign References:
| KR101504969B1 | 2015-03-24 | |||
| KR20180071030A | 2018-06-27 | |||
| KR20190061181A | 2019-06-05 | |||
| KR20070085864A | 2007-08-27 | |||
| KR20190124656A | 2019-11-05 | |||
| KR20190050017A | 2019-05-10 | |||
| KR102126199B1 | 2020-06-24 | |||
| KR20190094124A | 2019-08-12 | |||
| KR102019277B1 | 2019-09-06 | |||
| KR20180054523A | 2018-05-24 | |||
| KR20190090754A | 2019-08-02 |
Other References:
JAMES D. MCCULLY, J. VIS. EXP., no. 91, 2014, pages 51682
Attorney, Agent or Firm:
RYU, Jong Woo et al. (KR)
Download PDF: