Title:
INORGANIC POROUS SUPPORT AND METHOD FOR PRODUCING NUCLEIC ACID USING SAME
Document Type and Number:
WIPO Patent Application WO/2020/202953
Kind Code:
A1
Abstract:
The present invention provides: an inorganic porous support which enables the further improvement in the purity of a nucleic acid in the production of the nucleic acid, the inorganic porous support comprising an inorganic porous body which has a linker represented by general formula (1) (wherein the bond marked with "*" represents a bond to an oxygen atom in a silanol group in the inorganic porous body; n represents an integer such as 1; R's independently represent an alkyl group which has 3 to 10 carbon atoms and may have a substituent such as an alkoxy group; and L represents a single bond, an alkylene group having 1 to 20 carbon atoms or an alkylene group having 2 to 20 carbon atoms, and is a group containing -CH2-Q-CH2-, i.e., a group in which a group Q selected from the group consisting of –O- and others is inserted in at least one -CH2-CH2- group constituting the alkylene group) and has a survival bone rate (SBR) value of 5.0% or more; and a method for producing a nucleic acid using the inorganic porous support.
Inventors:
HARA SYUSAKU (JP)
KITAHARA MASAKI (JP)
HARA TAKASHI (JP)
ARIMURA TAKASHI (JP)
KITAHARA MASAKI (JP)
HARA TAKASHI (JP)
ARIMURA TAKASHI (JP)
Application Number:
PCT/JP2020/008325
Publication Date:
October 08, 2020
Filing Date:
February 28, 2020
Export Citation:
Assignee:
SUMITOMO CHEMICAL CO (JP)
International Classes:
B01J31/26; B01J32/00; C01B33/12; C01B39/36; C07H21/00; C12N15/09; C07F7/18
Domestic Patent References:
| WO2013062105A1 | 2013-05-02 | |||
| WO2013027843A1 | 2013-02-28 | |||
| WO2012017919A1 | 2012-02-09 | |||
| WO2013103146A1 | 2013-07-11 | |||
| WO2017188042A1 | 2017-11-02 |
Foreign References:
| CN108176387A | 2018-06-19 | |||
| JP2011088843A | 2011-05-06 | |||
| JP2006502856A | 2006-01-26 | |||
| JP2019067997A | 2019-04-25 | |||
| US20090005536A1 | 2009-01-01 | |||
| US3687808A | 1972-08-29 | |||
| JP5875843B2 | 2016-03-02 | |||
| JP2010120780A | 2010-06-03 | |||
| US20120035246A1 | 2012-02-09 |
Other References:
TOSOH RESEARCH TECHNOLOGY REVIEW, vol. 45, 2001
A.P. GUZAEVM. MANOHARAN, J AMCHEM SOC, vol. 125, 2003, pages 2380 - 2381
R.K. KUMARA.P. GUZAEVC. RENTELV.T. RAVIKUMAR, TETRAHEDRON, vol. 62, 2006, pages 4528
"Concise Encyclopedia Of Polymer Science And Engineering", 1990, JOHN WILEY & SONS, pages: 858 - 859
ENGLISCH ET AL.: "Angewandte Chemie", vol. 30, 1991, pages: 613
"Reviews by Chakhmakhcheva: Protective Groups in the Chemical Synthesis of Oligoribonucleotides", RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, vol. 39, no. 1, 2013, pages 1 - 21
CAS, no. RN: 919-30-2
See also references of EP 3950124A4
A.P. GUZAEVM. MANOHARAN, J AMCHEM SOC, vol. 125, 2003, pages 2380 - 2381
R.K. KUMARA.P. GUZAEVC. RENTELV.T. RAVIKUMAR, TETRAHEDRON, vol. 62, 2006, pages 4528
"Concise Encyclopedia Of Polymer Science And Engineering", 1990, JOHN WILEY & SONS, pages: 858 - 859
ENGLISCH ET AL.: "Angewandte Chemie", vol. 30, 1991, pages: 613
"Reviews by Chakhmakhcheva: Protective Groups in the Chemical Synthesis of Oligoribonucleotides", RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, vol. 39, no. 1, 2013, pages 1 - 21
CAS, no. RN: 919-30-2
See also references of EP 3950124A4
Attorney, Agent or Firm:
YAMAO, Norihito et al. (JP)
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