Title:
INSULIN-RESISTANT DISEASE MODEL CELL
Document Type and Number:
WIPO Patent Application WO/2023/238877
Kind Code:
A1
Abstract:
Provided is a model cell for fatty liver or an insulin-resistant disease state, the model cell comprising a hepatic cell derived from a non-human animal in which at least 70% of the liver is replaced by human hepatic cells.
Inventors:
KAKUNI MASAKAZU (JP)
TAKAHASHI MASAKI (JP)
YOSHIKAWA NAMI (JP)
TAKAHASHI MASAKI (JP)
YOSHIKAWA NAMI (JP)
Application Number:
PCT/JP2023/021083
Publication Date:
December 14, 2023
Filing Date:
June 07, 2023
Export Citation:
Assignee:
PHOENIXBIO CO LTD (JP)
International Classes:
C12N5/071; C12Q1/6851; C12Q1/686
Domestic Patent References:
| WO2021038892A1 | 2021-03-04 |
Other References:
MIREN HIROFUMI: "Relationship with type 2 diabetes -Controlled by hepatokine-", JOURNAL OF THE JAPANESE SOCIETY OF INTERNAL MEDICINE, vol. 105, no. 1, 1 January 2016 (2016-01-01), pages 25 - 30, XP093113896
Attorney, Agent or Firm:
KOBAYASHI Hiroshi et al. (JP)
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