Title:
INTERCALATOR AND METHOD OF GENE DETECTION USING THE SAME
Document Type and Number:
WIPO Patent Application WO/2006/030788
Kind Code:
A1
Abstract:
An intercalator that through suppression of any fluorescence quenching of fluorochrome in the dry state, realizes operation simplification and high-sensitivity detection; and a method of gene detection using the same. There is provided an intercalator comprising a binding part capable of binding to a double-stranded DNA and at least one chromogenic part consisting of an organic EL dye and linked via a coupling part to the binding part. By virtue of the use of the organic EL dye in the chromogenic part, there can be accomplished a high-sensitivity detection even in the dry state.
Inventors:
ISOBE SHINICHIRO (JP)
Application Number:
PCT/JP2005/016847
Publication Date:
March 23, 2006
Filing Date:
September 13, 2005
Export Citation:
Assignee:
ISOBE SHINICHIRO (JP)
International Classes:
C12Q1/68
Domestic Patent References:
| WO2004003551A1 | 2004-01-08 |
Foreign References:
| JP2003344407A | 2003-12-03 | |||
| JP2002333446A | 2002-11-22 | |||
| JPH04355369A | 1992-12-09 | |||
| JP2004000245A | 2004-01-08 |
Other References:
NOJIMA T. ET AL: "Keikosei Nuikomigata Intercalator o Mochiita Nihonsa Kakusan no Kenshutsu", THE CHEMICAL SOCIETY OF JAPAN KOEN YOKOSHU, vol. 82, 2002, pages 135, XP002998879
ISOBE S. ET AL: "Ryo Okikaeki Mattan ni Donyu shita Shinki Naphthalene Dimide Yudotai no Gosei to Bunseki Kagakuteki Riyo", BUNSEKI KAGAKU TORONKAI KOEN YOSHISHU, vol. 63, 2002, pages 98, XP002998880
ISOBE S. ET AL: "Ryo Okikaeki Mattan ni Donyu shita Shinki Naphthalene Dimide Yudotai no Gosei to Bunseki Kagakuteki Riyo", BUNSEKI KAGAKU TORONKAI KOEN YOSHISHU, vol. 63, 2002, pages 98, XP002998880
Attorney, Agent or Firm:
Kawamiya, Osamu (IMP Building 3-7, Shiromi 1-chome, Chuo-ku, Osaka-sh, Osaka 01, JP)
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