Title:
INTERNAL CYCLIC SULPHIAMIDINE AMIDE-ARYL AMIDE COMPOUND AND USE THEREOF FOR TREATING HEPATITIS B
Document Type and Number:
WIPO Patent Application WO/2020/143798
Kind Code:
A1
Abstract:
The invention relates to an internal cyclic sulphiamidine amide-aryl amide compound and a use thereof for treating hepatitis B. Specifically, disclosed is a compound that may act as an HBV replication inhibitor and that has a structure represented by chemical formula (L), or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt, a hydrate or a solvent thereof. See the description for detailed definitions of each group. The present invention also relates to a pharmaceutical composition containing the compound and a use thereof for treating hepatitis B.
Inventors:
WANG ZHE (CN)
ZENG ZHIHONG (CN)
ZHANG LEI (CN)
ZENG ZHIHONG (CN)
ZHANG LEI (CN)
Application Number:
PCT/CN2020/071523
Publication Date:
July 16, 2020
Filing Date:
January 10, 2020
Export Citation:
Assignee:
SHANGHAI LONGWOOD BIOPHARMACEUTICALS CO LTD (CN)
International Classes:
C07D513/04; A61K31/407; A61K31/4162; A61K31/554; A61P31/20
Domestic Patent References:
| WO2019011323A1 | 2019-01-17 | |||
| WO2018153326A1 | 2018-08-30 | |||
| WO2013006394A1 | 2013-01-10 | |||
| WO2013096744A1 | 2013-06-27 |
Foreign References:
| CN109251212A | 2019-01-22 | |||
| CN108264520A | 2018-07-10 | |||
| CN109251158A | 2019-01-22 | |||
| CN108250122A | 2018-07-06 | |||
| CN108250121A | 2018-07-06 | |||
| CN108341810A | 2018-07-31 |
Other References:
WEBER ET AL., ANTIVIRAL RES., vol. 54, pages 69 - 78
See also references of EP 3909957A4
See also references of EP 3909957A4
Attorney, Agent or Firm:
XU & PARTNERS, LLC. (CN)
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