Title:
INTESTINAL BACTERIA COUNT REDUCING AGENT
Document Type and Number:
WIPO Patent Application WO/2022/201775
Kind Code:
A1
Abstract:
An intestinal bacteria count reducing agent according to one aspect of the present invention contains silicon particles or silicon fine particles and reduces the number of intestinal bacteria. By using this intestinal bacteria count reducing agent, it is possible to reduce the number of intestinal bacteria through a new action that cannot be explained by the conventionally-known hydrogen-generating ability of silicon particles or silicon fine particles, which is, in other words, the ability to annihilate hydroxyl radicals.
Inventors:
KAYAMA HISAKO (JP)
TAKEDA KIYOSHI (JP)
KOBAYASHI HIKARU (JP)
KOBAYASHI YUKI (JP)
TAKEDA KIYOSHI (JP)
KOBAYASHI HIKARU (JP)
KOBAYASHI YUKI (JP)
Application Number:
PCT/JP2022/001299
Publication Date:
September 29, 2022
Filing Date:
January 17, 2022
Export Citation:
Assignee:
UNIV OSAKA (JP)
International Classes:
A61K33/00; A23L33/10; A61K9/14; A61P31/04; A61P43/00
Domestic Patent References:
| WO2019021769A1 | 2019-01-31 |
Foreign References:
| RU2214826C2 | 2003-10-27 | |||
| JP2019214556A | 2019-12-19 | |||
| JP2020007300A | 2020-01-16 | |||
| JP2020079240A | 2020-05-28 | |||
| JP2020079228A | 2020-05-28 | |||
| JP2020117480A | 2020-08-06 | |||
| JP2020117481A | 2020-08-06 | |||
| JP2020117482A | 2020-08-06 | |||
| JP2020117483A | 2020-08-06 | |||
| JP2020117484A | 2020-08-06 | |||
| JP2020117485A | 2020-08-06 | |||
| JP2020117486A | 2020-08-06 |
Other References:
LESTARI SRI UTAMI, ANDRIAN ANDI, MUSTAFINA A S, RAKHMATULLIN S G, SIZOVA Е А: "IOP Conference Series: Earth and Environmental Science Improving the efficiency of poultry meat production by feeding ultrafine silicon You may also like Effects of Urin Cow Dosage on Growth and Production of Sorgum Plant (Sorghum Bicolor L) on Peat Land Improving the efficiency of poultry meat prod", EARTH ENVIRON. SCI. SERIES: EARTH AND ENVIRONMENTAL SCIENCE, IOP PUBLISHING, 7 January 2021 (2021-01-07), pages 12039, XP055971007, Retrieved from the Internet [retrieved on 20221013]
RUDENKO PAVEL, VATNIKOV YURY, KULIKOV EVGENY, SACHIVKINA NADEZHDA, RUDENKO ANDREI, RUDENKO VICTORIA, GADZHIKURBANOV ANVAR, MURYLEV: "Experimental and Clinical Justification of the use of Probiotic-Sorption Drugs in Veterinary Surgery", SYSTEMATIC REVIEWS IN PHARMACY, vol. 11, no. 04, 1 June 2020 (2020-06-01), XP055971009, ISSN: 0976-2779, DOI: 10.31838/srp.2020.4.40
BREDECK GERRIT, KÄMPFER ANGELA A. M., SOFRANKO ADRIANA, WAHLE TINA, LISON DOMINIQUE, AMBROISE JÉRÔME, STAHLMECKE BURKHARD, ALBRECH: "Effects of dietary exposure to the engineered nanomaterials CeO 2 , SiO 2 , Ag, and TiO 2 on the murine gut microbiome", NANOTOXICOLOGY, INFORMA HEALTHCARE, GB, GB , pages 1 - 17, XP055971011, ISSN: 1743-5390, DOI: 10.1080/17435390.2021.1940339
ANDOH, FACTORS INFLUENCING THE GUT MICROBIOTA STRUCTURE, MODERN MEDIA, vol. 65, 2019, pages 72 - 79
MITSUNORI IKEDA ET AL.: "Hydrogen-Rich Saline Regulates Intestinal Barrier Dysfunction, Dysbiosis, and Bacterial Translocation in a Murine Model of Sepsis", SHOCK, vol. 50, no. 6, 2018, pages 640 - 647
RUDENKO PAVEL, VATNIKOV YURY, KULIKOV EVGENY, SACHIVKINA NADEZHDA, RUDENKO ANDREI, RUDENKO VICTORIA, GADZHIKURBANOV ANVAR, MURYLEV: "Experimental and Clinical Justification of the use of Probiotic-Sorption Drugs in Veterinary Surgery", SYSTEMATIC REVIEWS IN PHARMACY, vol. 11, no. 04, 1 June 2020 (2020-06-01), XP055971009, ISSN: 0976-2779, DOI: 10.31838/srp.2020.4.40
BREDECK GERRIT, KÄMPFER ANGELA A. M., SOFRANKO ADRIANA, WAHLE TINA, LISON DOMINIQUE, AMBROISE JÉRÔME, STAHLMECKE BURKHARD, ALBRECH: "Effects of dietary exposure to the engineered nanomaterials CeO 2 , SiO 2 , Ag, and TiO 2 on the murine gut microbiome", NANOTOXICOLOGY, INFORMA HEALTHCARE, GB, GB , pages 1 - 17, XP055971011, ISSN: 1743-5390, DOI: 10.1080/17435390.2021.1940339
ANDOH, FACTORS INFLUENCING THE GUT MICROBIOTA STRUCTURE, MODERN MEDIA, vol. 65, 2019, pages 72 - 79
MITSUNORI IKEDA ET AL.: "Hydrogen-Rich Saline Regulates Intestinal Barrier Dysfunction, Dysbiosis, and Bacterial Translocation in a Murine Model of Sepsis", SHOCK, vol. 50, no. 6, 2018, pages 640 - 647
Attorney, Agent or Firm:
KOUNO Hiroaki (JP)
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