IONIC LIQUID, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF

Title:

IONIC LIQUID, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF

Document Type and Number:

WIPO Patent Application WO/2022/222844

Kind Code:

A1

Abstract:

Disclosed in the present invention are an ionic liquid, a preparation method therefor, and an application thereof. The ionic liquid is prepared from vitamin A compounds and choline compounds, has the characteristics of good solubility and high permeability, can significantly improve oral availability, has significant formulation application advantages, and can be widely and effectively used in various formulations.

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Inventors:

QI JIANPING (CN)
WU XIYING (CN)
WU WEI (CN)
HU TAO (CN)
LU YI (CN)

Application Number:

PCT/CN2022/086902

Publication Date:

October 27, 2022

Filing Date:

April 14, 2022

Export Citation:

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Assignee:

NANJING INDETEK LABORATORY CO LTD (CN)
UNIV FUDAN (CN)

International Classes:

A61K8/41; C07C403/20; A61Q19/00; C07C213/08; C07C215/40

Foreign References:

US4727064A	1988-02-23
CN102126968A	2011-07-20
CN101260051A	2008-09-10
US4857525A	1989-08-15
CN105315164A	2016-02-10
CN1854120A	2006-11-01

Other References:

PITHA, J. ET AL.: "Hydroxypropyl-β-Cyclodextrin: Preparation and Characterization Effects on Solubility of Drugs", INTERNATIONAL JOURNAL OF PHARMACEUTICS, vol. 29, no. 1, 31 March 1986 (1986-03-31), XP025502232, ISSN: 0378-5173, DOI: 10.1016/0378-5173(86)90201-2

Attorney, Agent or Firm:

BEIJING ORIGINTELLIGENCE IP LAW FIRM (CN)

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