Title:
ISOINDOLINONE COMPOUND AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/025112
Kind Code:
A1
Abstract:
Provided are an isoindolinone compound represented by structural formula (I) or a pharmaceutically acceptable salt thereof, and a use thereof in the treatment of proliferative diseases. Further provided is a pharmaceutical composition comprising the compound or the salt thereof and a pharmaceutically acceptable carrier.
Inventors:
FU LIQIANG (CN)
KONG LINGLONG (CN)
ZHANG LEI (CN)
LU GANG (US)
XIA YIFENG (US)
LU CHIN-CHUN (US)
SURKA CHRISTINE (US)
KONG LINGLONG (CN)
ZHANG LEI (CN)
LU GANG (US)
XIA YIFENG (US)
LU CHIN-CHUN (US)
SURKA CHRISTINE (US)
Application Number:
PCT/CN2022/114058
Publication Date:
March 02, 2023
Filing Date:
August 22, 2022
Export Citation:
Assignee:
HANGZHOU GLUBIO PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D401/14; A61K31/4035; A61P35/00; C07D209/92; C07D419/14
Domestic Patent References:
| WO2020210630A1 | 2020-10-15 | |||
| WO2022081927A1 | 2022-04-21 | |||
| WO2022032132A1 | 2022-02-10 |
Other References:
SCIENCE, vol. 343, 2014, pages 301 - 305
NATURE CHEMICAL BIOLOGY, vol. 14, 2018, pages 981 - 987
PAQUETTE, LEO A.: "Principles of Modern Heterocyclic Chemistry", 1968, W. A. BENJAMIN
"The Chemistry of Heterocyclic Compounds, A series of Monographs", 1950, JOHN WILEY & SONS
J. AM. CHEM. SOC., vol. 82, 1960, pages 5566
"REMINGTON'S PHARMACEUTICAL SCIENCES", 1995, MACK PUBLISHING COMPANY
NATURE CHEMICAL BIOLOGY, vol. 14, 2018, pages 981 - 987
PAQUETTE, LEO A.: "Principles of Modern Heterocyclic Chemistry", 1968, W. A. BENJAMIN
"The Chemistry of Heterocyclic Compounds, A series of Monographs", 1950, JOHN WILEY & SONS
J. AM. CHEM. SOC., vol. 82, 1960, pages 5566
"REMINGTON'S PHARMACEUTICAL SCIENCES", 1995, MACK PUBLISHING COMPANY
Attorney, Agent or Firm:
KING & WOOD MALLESONS (CN)
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