ISOLATING METHOD FOR UMBILICAL CORD BLOOD-DERIVED PLURIPOTENT STEM CELLS EXPRESSING ZNF281

WIPO Patent Application WO/2010/107192

A3

The present invention relates to an isolating method for umbilical cord blood-derived pluripotent stem cells which is characterized by culturing monocytes isolated from umbilical cord blood in a culture vessel containing fibronectin and then harvesting stem cells from culture, the umbilical cord blood-derived pluripotent stem cells isolated thereby, and a cell therapeutic agent containing the umbilical cord blood-derived pluripotent stem cells or differentiated cells therefrom. In addition, the present invention relates to a novel culture media for stem cells, a culture method for stem cells which is characterized by culturing and proliferating stem cells in the culture media, and a method for increasing stemness of stem cells which is characterized by sphere culture or three-dimensional culture of stem cells.

KANG KYUNG SUN (KR)
ROH KYOUNG HWAN (KR)

PCT/KR2010/001338

February 24, 2011

March 03, 2010

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SUN R & DB FOUNDATION (KR)
KANG KYUNG SUN (KR)
ROH KYOUNG HWAN (KR)

C12N5/074; C12N5/02; C12N5/07

PENN, M.S., CONTEMPORARY CARDIOLOGY STEM CELLS AND MYOCARDIAL REGENERATION, 2007, pages 67 - 81
EXPERIMENTAL HEMATOLOGY, vol. 34, 2006, pages 1589 - 1595
CELL, vol. 132, 2008, pages 1049 - 1061
CYTOTECHNOLOGY, vol. 54, 2007, pages 121 - 133

SON, Min (6th Floor City Air Tower,159-9, Samseong-dong, Gangnam-gu, Seoul 135-973, KR)

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