ISOXAZOLE, DIHYDROISOXAZOLE, AND OXADIAZOLE SUBSTITUTED IMIDAZO RING COMPOUNDS AND METHODS

Title:

ISOXAZOLE, DIHYDROISOXAZOLE, AND OXADIAZOLE SUBSTITUTED IMIDAZO RING COMPOUNDS AND METHODS

Document Type and Number:

WIPO Patent Application WO2006065280

Kind Code:

A3

Abstract:

Imidazo ring compounds, (e.g., imidazo[4,5-c]pyridine, imidazo[4,5-c]quinoline, 6,7,8,9-tetrahydro imidazo[4,5-c]quinoline, imidazo[4,5-c]naphthyridine, and 6,7,8,9-tetrahydro imidazo[4,5-c]naphthyridine compounds) having an isoxazole, dihydroisoxazole, or oxadiazole substituent at the 1-position, pharmaceutical compositions containing the compounds, intermediates, and methods of making and methods of use of these compounds as immunomodulators, for modulating cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.

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Inventors:

MOSER WILLIAM H (US)
MOSEMAN JOAN T (US)
KSHIRSAGAR TUSHAR A (US)
HEPPNER PHILIP D (US)

Application Number:

PCT/US2005/021570

Publication Date:

July 20, 2006

Filing Date:

June 17, 2005

Export Citation:

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Assignee:

3M INNOVATIVE PROPERTIES CO (US)
MOSER WILLIAM H (US)
MOSEMAN JOAN T (US)
KSHIRSAGAR TUSHAR A (US)
HEPPNER PHILIP D (US)

International Classes:

A61K31/44; C07D471/02

Foreign References:

US6716988B2	2004-04-06
US6720333B2	2004-04-13
US6720334B2	2004-04-13
US6720422B2	2004-04-13

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