Title:
KERATIN BD-2, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/083191
Kind Code:
A1
Abstract:
The present invention provides a keratin BD-2, an encoding nucleic acid molecule thereof, an expression vector thereof, a host cell thereof, and a pharmaceutical composition comprising the keratin. The keratin BD-2 can be used for preparing antipyretic and analgesic, antitussive and expectorant, and antiepileptic drugs.
Inventors:
YU SHISHAN (CN)
WANG XIAOLIANG (CN)
QU JING (CN)
SHI GUORU (CN)
LI MI (CN)
WANG LING (CN)
CAI JIE (CN)
LI JIANG (CN)
WANG XIAOLIANG (CN)
QU JING (CN)
SHI GUORU (CN)
LI MI (CN)
WANG LING (CN)
CAI JIE (CN)
LI JIANG (CN)
Application Number:
PCT/CN2020/124327
Publication Date:
May 06, 2021
Filing Date:
October 28, 2020
Export Citation:
Assignee:
INST OF MATERIA MEDICA CHINESE ACADEMY OF MEDICAL SCICENCES (CN)
International Classes:
C07K14/47; A61K38/17; A61P11/00; A61P25/08; A61P29/00; C12N15/12; C12N15/63
Foreign References:
CN109078023A | 2018-12-25 | |||
CN1324859A | 2001-12-05 | |||
CN102993291A | 2013-03-27 | |||
US5994081A | 1999-11-30 |
Other References:
DATABASE Nucleotide 9 June 2008 (2008-06-09), ANONYMOUS: "Bos taurus keratin 34, mRNA (cDNA clone MGC:139887 IMAGE:8284533), complete cds", XP055806867, retrieved from NCBI Database accession no. BC118281
WU HONGXING, CHEN JINGGUO , LI ZHENHUA: "Effect of Antelope Horn Decoction on Serum TNF-α and IL-6 in Children with Persistent Fever", WU HONGXING, CHEN JINGGUO , LI ZHENHUA, vol. 27, no. 14, 31 July 2018 (2018-07-31), pages 79 - 80, XP055806911, ISSN: 1007-8517
ZHANG LONGFEI , HU JINGHONG , ZHANG YONGQING: "Research Overview of the Pharmacological Action of Cornu Saigae Tataricae", CHINA MEDICAL HERALD, vol. 10, no. 28, 5 October 2013 (2013-10-05), pages 23 - 26+33, XP055806914, ISSN: 1673-7210
WU HONGXING, CHEN JINGGUO , LI ZHENHUA: "Effect of Antelope Horn Decoction on Serum TNF-α and IL-6 in Children with Persistent Fever", WU HONGXING, CHEN JINGGUO , LI ZHENHUA, vol. 27, no. 14, 31 July 2018 (2018-07-31), pages 79 - 80, XP055806911, ISSN: 1007-8517
ZHANG LONGFEI , HU JINGHONG , ZHANG YONGQING: "Research Overview of the Pharmacological Action of Cornu Saigae Tataricae", CHINA MEDICAL HERALD, vol. 10, no. 28, 5 October 2013 (2013-10-05), pages 23 - 26+33, XP055806914, ISSN: 1673-7210
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