Title:
KIT FOR PREPARING NANOPARTICLES CONTAINING DRUG AND COMPRISING NO AMPHIPHILIC POLYMERS
Document Type and Number:
WIPO Patent Application WO/2022/231374
Kind Code:
A1
Abstract:
The present invention relates to a kit for preparing nanoparticles containing a drug and, more specifically, to a kit for preparing drug-containing nanoparticles, the kit enabling a drug to be easily contained in nanoparticles by simple mixing only, preferably, in a specific weight ratio, the drug and nanoparticles containing a cationic compound and a polylactate, as kit constituent components comprising no amphiphilic polymers,, and being designed to enable the efficiency of drug delivery into cells to be greater than that of a kit comprising an amphiphilic polymer.
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Inventors:
LEE SO JIN (KR)
KIM GO EUN (KR)
PARK JOON YOUNG (KR)
KIM GO EUN (KR)
PARK JOON YOUNG (KR)
Application Number:
PCT/KR2022/006174
Publication Date:
November 03, 2022
Filing Date:
April 29, 2022
Export Citation:
Assignee:
SAMYANG HOLDINGS CORP (KR)
International Classes:
A61K9/51
Domestic Patent References:
| WO2018220553A1 | 2018-12-06 |
Foreign References:
| KR20200016806A | 2020-02-17 | |||
| KR20110077818A | 2011-07-07 | |||
| KR20190127277A | 2019-11-13 | |||
| KR20170032858A | 2017-03-23 |
Other References:
DE PAULA DBENTLEY MVMAHATO RI: "Hydrophobization and bioconjugation for enhanced siRNA delivery and targeting", RNA, vol. 13, 2007, pages 431 - 56
GARY DJPURI NWON YY: "Polymer-based siRNA delivery: Perspectives on the fundamental and phenomenological distinctions from polymer-based DNA delivery", J CONTROL RELEASE, vol. 121, 2007, pages 64 - 73, XP022179907, DOI: 10.1016/j.jconrel.2007.05.021
GARY DJPURI NWON YY: "Polymer-based siRNA delivery: Perspectives on the fundamental and phenomenological distinctions from polymer-based DNA delivery", J CONTROL RELEASE, vol. 121, 2007, pages 64 - 73, XP022179907, DOI: 10.1016/j.jconrel.2007.05.021
Attorney, Agent or Firm:
HANSUNG INTELLECTUAL PROPERTY (KR)
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