Title:
L-AMINO ACID-PRODUCING MICROORGANISM EXHIBITING INCREASED Α-GLUCOSIDASE ACTIVITY, AND L-AMINO ACID PRODUCTION METHOD USING SAME
Document Type and Number:
WIPO Patent Application WO/2020/067618
Kind Code:
A1
Abstract:
The present application relates to an L-amino acid-producing microorganism exhibiting reinforced α-glucosidase activity, and an L-amino acid production method using same. The L-amino acid-producing Corynebacterium sp. microorganism, according to the present application, exhibits reinforced α-glucosidase activity, thereby enabling L-amino acid production yield to increase, and thus the microorganism may be very usefully employed for use in L-amino acid production.
Inventors:
KIM KYUNGRIM (KR)
BYUN HYO JEONG (KR)
LEE KWANG WOO (KR)
KIM HYUNG JOON (KR)
SHIN YONG UK (KR)
BYUN HYO JEONG (KR)
LEE KWANG WOO (KR)
KIM HYUNG JOON (KR)
SHIN YONG UK (KR)
Application Number:
PCT/KR2019/004228
Publication Date:
April 02, 2020
Filing Date:
April 09, 2019
Export Citation:
Assignee:
CJ CHEILJEDANG CORP (KR)
International Classes:
C12N15/77; C12N9/26; C12P13/04; C12P13/06; C12P13/08
Foreign References:
| US9228215B2 | 2016-01-05 | |||
| KR101592140B1 | 2016-02-22 | |||
| KR100838038B1 | 2008-06-12 | |||
| KR101484108B1 | 2015-01-19 | |||
| KR100620092B1 | 2006-09-08 | |||
| KR101783170B1 | 2017-09-29 | |||
| KR100924065B1 | 2009-10-27 | |||
| KR0159812B1 | 1998-11-16 |
Other References:
DATABASE Protein 26 September 2017 (2017-09-26), "alpha-glucosidase [Bifidobacterium adolescentis]", XP055654149, retrieved from NCBI Database accession no. WP_011743867.1
DATABASE Protein 7 June 2016 (2016-06-07), "alpha-glucosidase [Erwinia amylovora]", XP055654150, retrieved from NCBI Database accession no. WP _004164340.1
DATABASE NCBI 15 March 2017 (2017-03-15), "Saccharomyces cerevisiae S288C", Database accession no. NP_01 1803.3
PEARSON ET AL., PROC. NATL. ACAD. SCI. USA, vol. 85, 1988, pages 2444
RICE ET AL., TRENDS GENET., vol. 16, 2000, pages 276 - 277
NEEDLEMANWUNSCH, J. MOL. BIOL., vol. 48, 1970, pages 443 - 453
DEVEREUX, J. ET AL., NUCLEIC ACIDS RESEARCH, vol. 12, no. 387, 1984
BLASTP, BLASTNFASTA (ATSCHUL, [S.] [F., J MOLEC BIOL, vol. 215, 1990, pages 403
"Guide to Huge Computers", 1994, ACADEMIC PRESS
CARILLO, SIAM J APPLIED MATH, vol. 48, 1988, pages 1073
NEEDLEMAN ET AL., J MOL BIOL., vol. 48, 1970, pages 443
GRIBSKOV ET AL., NUCL. ACIDS RES., vol. 14, 1986, pages 6745
"National Biomedical Research Foundation", 1979, article "Atlas Of Protein Sequence And Structure", pages: 353 - 358
SAMBROOK ET AL.: "Molecular Cloning", 1989, COLD SPRING HARBOR LABORATORY PRESS
VAN DER REST ET AL., APPL. MICROBIOL. BIOTECHNOL., vol. 52, 1999, pages 541 - 545
BINDER ET AL., GENOME BIOLOGY, vol. 13, 2012
R. WINKELS, S. ET AL., APPL. MICROBIOL. BIOTECHNOL., vol. 45, 1996, pages 612 - 620
S. MORBACH ET AL., APPL. ENVIRO. MICROBIOL., vol. 62, no. 12, 1996, pages 4345 - 4351
See also references of EP 3656863A4
DATABASE Protein 7 June 2016 (2016-06-07), "alpha-glucosidase [Erwinia amylovora]", XP055654150, retrieved from NCBI Database accession no. WP _004164340.1
DATABASE NCBI 15 March 2017 (2017-03-15), "Saccharomyces cerevisiae S288C", Database accession no. NP_01 1803.3
PEARSON ET AL., PROC. NATL. ACAD. SCI. USA, vol. 85, 1988, pages 2444
RICE ET AL., TRENDS GENET., vol. 16, 2000, pages 276 - 277
NEEDLEMANWUNSCH, J. MOL. BIOL., vol. 48, 1970, pages 443 - 453
DEVEREUX, J. ET AL., NUCLEIC ACIDS RESEARCH, vol. 12, no. 387, 1984
BLASTP, BLASTNFASTA (ATSCHUL, [S.] [F., J MOLEC BIOL, vol. 215, 1990, pages 403
"Guide to Huge Computers", 1994, ACADEMIC PRESS
CARILLO, SIAM J APPLIED MATH, vol. 48, 1988, pages 1073
NEEDLEMAN ET AL., J MOL BIOL., vol. 48, 1970, pages 443
GRIBSKOV ET AL., NUCL. ACIDS RES., vol. 14, 1986, pages 6745
"National Biomedical Research Foundation", 1979, article "Atlas Of Protein Sequence And Structure", pages: 353 - 358
SAMBROOK ET AL.: "Molecular Cloning", 1989, COLD SPRING HARBOR LABORATORY PRESS
VAN DER REST ET AL., APPL. MICROBIOL. BIOTECHNOL., vol. 52, 1999, pages 541 - 545
BINDER ET AL., GENOME BIOLOGY, vol. 13, 2012
R. WINKELS, S. ET AL., APPL. MICROBIOL. BIOTECHNOL., vol. 45, 1996, pages 612 - 620
S. MORBACH ET AL., APPL. ENVIRO. MICROBIOL., vol. 62, no. 12, 1996, pages 4345 - 4351
See also references of EP 3656863A4
Attorney, Agent or Firm:
SON, Min (KR)
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