Title:
LIPOSOMAL OLIGONUCLEOTIDE COMPOSITIONS FOR MODULATING ras GENE EXPRESSION
Document Type and Number:
WIPO Patent Application WO1999022772
Kind Code:
A9
Abstract:
Pharmaceutical compostions comprising liposomes containing antisense oligonucleotides are provided for the modulation of expression of the human ras gene in both the normal (wildtype) and activated (mutant) forms.
Inventors:
HARDEE GREGORY E (US)
GEARY RICHARD S (US)
LEVIN ARTHUR (US)
TEMPLIN MICHAEL V (US)
HOWARD RANDY (US)
MEHTA RAHUL C (US)
GEARY RICHARD S (US)
LEVIN ARTHUR (US)
TEMPLIN MICHAEL V (US)
HOWARD RANDY (US)
MEHTA RAHUL C (US)
Application Number:
PCT/US1998/022821
Publication Date:
September 02, 1999
Filing Date:
October 28, 1998
Export Citation:
Assignee:
ISIS PHARMACEUTICALS INC (US)
HARDEE GREGORY E (US)
GEARY RICHARD S (US)
LEVIN ARTHUR (US)
TEMPLIN MICHAEL V (US)
HOWARD RANDY (US)
MEHTA RAHUL C (US)
HARDEE GREGORY E (US)
GEARY RICHARD S (US)
LEVIN ARTHUR (US)
TEMPLIN MICHAEL V (US)
HOWARD RANDY (US)
MEHTA RAHUL C (US)
International Classes:
A61K9/127; C07H21/00; C12N15/113; A61K38/00; (IPC1-7): A61K48/00; C07H21/02; C07H21/04; C12N15/11
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