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Title:
LACTICASEIBACILLUS RHAMNOSUS FOR PREVENTING AND/OR TREATING DISEASES CAUSED BY REPRODUCTIVE TRACT FLORA DISORDER AND/OR BONE LOSS
Document Type and Number:
WIPO Patent Application WO/2022/100632
Kind Code:
A1
Abstract:
Lacticaseibacillus rhamnosus for preventing and/or treating diseases caused by the reproductive tract flora disorder and/or bone loss and an application thereof. The Lacticaseibacillus rhamnosus is OF44-15Ph10T, and the accession number thereof is GDMCC No:60406. The strain is capable of producing secretions such as lactic acid and hydrogen peroxide to inhibit the growth of the reproductive tract infection pathogenic bacteria, and is used for preventing and/or treating the reproductive tract infection disease. The strain can also inhibit bone loss so as to treat and improve osteoporosis.

Inventors:
ZHANG XIAOWEI (CN)
LV JINLI (CN)
ZHAO SHAOWEI (CN)
GAO MENGYU (CN)
ZOU YUANQIANG (CN)
XIAO LIANG (CN)
Application Number:
PCT/CN2021/129909
Publication Date:
May 19, 2022
Filing Date:
November 10, 2021
Export Citation:
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Assignee:
BGI SHENZHEN (CN)
International Classes:
C12N1/20; A23C9/123; A23L2/39; A23L33/135; A61K35/747; A61P15/02; A61P19/10; A61P31/04; A61P31/10; A61P31/20; A61P31/22; A61P33/02; C12R1/225
Foreign References:
CN112760247A2021-05-07
CN110016442A2019-07-16
CN108004188A2018-05-08
CN103889241A2014-06-25
US7063836B22006-06-20
EP3318262A22018-05-09
Other References:
ZHONG YAN , INGE TARNOW , SUI LONG: "Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 for Treatment and Prevention of Vaginal Infections", JOURNAL OF INTERNATIONAL OBSTETRICS AND GYNECOLOGY, vol. 40, no. 5, 15 October 2013 (2013-10-15), pages 428 - 431, XP055929843, ISSN: 1674-1870
CHEN, CHEN: "The Effect and Mechanism Research of Intestinal Probiotics on Osteoporosis", CHINESE DOCTORAL DISSERTATIONS FULL-TEXT DATABASE, 1 May 2018 (2018-05-01), pages 1 - 108, XP055929847
DADARWAL DINESH; PALMER COLIN; GRIEBEL PHILIP: "Mucosal immunity of the postpartum bovine genital tract", THERIOGENOLOGY, vol. 104, 1 January 1900 (1900-01-01), US , pages 62 - 71, XP085228023, ISSN: 0093-691X, DOI: 10.1016/j.theriogenology.2017.08.010
Attorney, Agent or Firm:
ZHIFAN & PARTNERS (CN)
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