LACTOBACILLUS AMYLOVORUS LAM1345 ISOLATE, COMPOSITION INCLUDING THE SAME AND USE THEREOF

Title:

LACTOBACILLUS AMYLOVORUS LAM1345 ISOLATE, COMPOSITION INCLUDING THE SAME AND USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2022/151669

Kind Code:

A1

Abstract:

Provided is an isolated strain of Lactobacillus amylovorus LAM1345, which is deposited at Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH under an accession number DSM 33510. Also provided are a composition including the isolated strain of Lactobacillus amylovorus LAM1345 for reducing trimethylamine (TMA) and/or trimethylamine-n-oxide (TMAO) levels, and use of the isolated strain of Lactobacillus amylovorus LAM1345 for treating a disease associated with at least an elevated one of TMA and TMAO levels in a subject.

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Inventors:

YOUNG SAN-LAND (CN)
TSEN HAU-YANG (CN)
HUNG CHEN-YING (CN)
CHIANG YU-CHENG (CN)

Application Number:

PCT/CN2021/103607

Publication Date:

July 21, 2022

Filing Date:

June 30, 2021

Export Citation:

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Assignee:

SYNBIO TECH INC (CN)

International Classes:

C12N1/20; A61K35/74; A61P3/00; A61P7/00; A61P9/00; C12R1/225

Domestic Patent References:

WO2009141427A2

2009-11-26

Foreign References:

CN101668534A	2010-03-10
CN105154371A	2015-12-16
KR20130088817A	2013-08-08

Other References:

PARK SUNG-SOO, LEE YEON-JOO, KANG HYUNO, YANG GARAM, HONG EUN JEONG, LIM JIN YEONG, OH SEJONG, KIM EUNGSEOK: "Lactobacillus amylovorus KU4 ameliorates diet-induced obesity in mice by promoting adipose browning through PPARγ signaling", SCIENTIFIC REPORTS, vol. 9, no. 1, 1 December 2019 (2019-12-01), pages 20152, XP055950409, DOI: 10.1038/s41598-019-56817-w
SHI YUE, ET AL.: "Research Progress on Lactobacillus amylovorus Application", JOURNAL OF GRASSLAND AND FORAGE SCIENCE, no. 6, 31 December 2020 (2020-12-31), pages 1 - 6, XP055950412, ISSN: 2096-3971, DOI: 10.3969/j.issn.2096-3971.2020.06.001

Attorney, Agent or Firm:

LINDA LIU & PARTNERS (CN)

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