Title:
LACTOBACILLUS CRISPATUS AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2015/067141
Kind Code:
A1
Abstract:
Provided are Lactobacillus crispatus 262-1 and inoculant containing the bacterial strain. The Lactobacillus crispatus 262-1 has the Deposit No. of CGMCC No. 6469 in the China General Microbiological Culture Collection Center, and has good acid production and H2O2 production capabilities, and good capability of adhering to vaginal epithelial cells, and dramatically resists bacterial vaginosis and various vaginal infections. Also provided are a use of the bacterial strain in preparation of drugs for preventing and/or treating gynecological diseases, and application thereof in woman health products such as medical instruments, disinfectant products or cosmetics.
Inventors:
LIU YANG (CN)
Application Number:
PCT/CN2014/089882
Publication Date:
May 14, 2015
Filing Date:
October 30, 2014
Export Citation:
Assignee:
SUZHOU OSEL BIO PHARM CO LTD (CN)
International Classes:
C12N1/20; A61K8/99; A61K35/74; A61P15/02; C12R1/225
Foreign References:
| CN103074270A | 2013-05-01 | |||
| CN1259874A | 2000-07-12 |
Other References:
DATABASE GENBANK [online] 2 November 2010 (2010-11-02), YAMAZAKI, M. ET AL.: "LACTOBACILLUS CRISPATUS GENE FOR 16S RRNA, PARTIAL SEQUENCE, STRAIN: CE3", XP055270263, retrieved from NCBI Database accession no. AB597000
DATABASE GENBANK [online] 31 January 2013 (2013-01-31), KANKAINEN, M. ET AL.: "LACTOBACILLUS CRISPATUS ST1 STRAIN ST1 16S RIBOSOMAL RNA, COMPLETE SEQUENCE", XP055270267, retrieved from NCBI Database accession no. NR_074986
HE, LIANG ET AL.: "16S rDNA Identification and Phylogenetic Analysis of Six Strains of Lactobacillus from Female Genital Tract", CHINESE JOURNAL OF GENERAL PRACTICE, vol. 11, no. 4, 30 April 2013 (2013-04-30), pages 617 - 618 AND 640, XP008180171
CHINESE PHARMACOPOEIA, 2010
See also references of EP 3040413A4
DATABASE GENBANK [online] 31 January 2013 (2013-01-31), KANKAINEN, M. ET AL.: "LACTOBACILLUS CRISPATUS ST1 STRAIN ST1 16S RIBOSOMAL RNA, COMPLETE SEQUENCE", XP055270267, retrieved from NCBI Database accession no. NR_074986
HE, LIANG ET AL.: "16S rDNA Identification and Phylogenetic Analysis of Six Strains of Lactobacillus from Female Genital Tract", CHINESE JOURNAL OF GENERAL PRACTICE, vol. 11, no. 4, 30 April 2013 (2013-04-30), pages 617 - 618 AND 640, XP008180171
CHINESE PHARMACOPOEIA, 2010
See also references of EP 3040413A4
Attorney, Agent or Firm:
SHIJIAZHUANG ZHONGZHIHUAQING INTELLECTUAL PROPERTY FIRM (SPECIAL GENERAL PARTNER) (CN)
石家庄众志华清知识产权事务所（特殊普通合伙） (CN)
石家庄众志华清知识产权事务所（特殊普通合伙） (CN)
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